Effects of Remifentanil Infusion on Emergence Delirium After Dental Surgery in Children

In this study, the investigators tried to show the effect of remifentanil on emergence delirium caused by sevoflurane used in general anesthesia.We planned a retrospective study. We formed two groups of 80 participants. One group included patients who were received remifentanil infusion during general anesthesia.The other group included patients who were received only sevoflurane inhalation anesthesia.

The patients included in the study were evaluated for emergence delirium in the postoperative period be evaluating the past recorded informations.

Study Overview

• Status: Completed
• Conditions: Emergence Delirium
• Intervention / Treatment: Other: The Paediatric Anaesthesia Emergence Delirium scale assesment which was recorded postoperatively

• Study Type: Observational
• Enrollment (Actual): 80

Contacts and Locations

Study Locations

• Turkey
  • Erzincan, Turkey
    • Nurcan Kutluer Karaca

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 2 years to 6 years (CHILD)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

All patients between 2 and 6 years old having American Society of Anesthesiologists score 1-2.

Description

Inclusion Criteria American Society of Anesthesiologists score 1-2

-

Exclusion Criteria:

• neurological disease, psychiatric illness

Study Plan

How is the study designed?

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Sevoflurane only; inhalation of sevoflurane during general anesthesia	Other: The Paediatric Anaesthesia Emergence Delirium scale assesment which was recorded postoperatively; routine remifentanil infusion during general anesthesia
Remifentanil and Sevoflurane; remifentanil infusion and inhalation of sevoflurane during general anesthesia	Other: The Paediatric Anaesthesia Emergence Delirium scale assesment which was recorded postoperatively; routine remifentanil infusion during general anesthesia

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
emergence delirium	incidence of emergence delirium	30 minute after operation

Collaborators and Investigators

• Sponsor: Erzincan University

Study record dates

Study Major Dates

• Study Start (ACTUAL): March 1, 2019
• Primary Completion (ACTUAL): September 30, 2019
• Study Completion (ACTUAL): September 30, 2019

Study Registration Dates

• First Submitted: November 8, 2019
• First Submitted That Met QC Criteria: March 6, 2020
• First Posted (ACTUAL): March 9, 2020

Study Record Updates

• Last Update Posted (ACTUAL): June 4, 2020
• Last Update Submitted That Met QC Criteria: June 2, 2020
• Last Verified: June 1, 2020

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Mental Disorders; Pathologic Processes; Nervous System Diseases; Postoperative Complications; Neurologic Manifestations; Confusion; Neurobehavioral Manifestations; Neurocognitive Disorders; Delirium; Emergence Delirium; Physiological Effects of Drugs; Central Nervous System Depressants; Anesthetics
• Other Study ID Numbers: Erzincan Universty

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No
• product manufactured in and exported from the U.S.: No