Association Between Early Childhood Caries, Low Birth Weight and Nutritional Risk Factors: (Cohort Study)

The aim of this study is to assess the ECC experience in children aged from 12 to 36 month with low birth weight children in comparison to normal birth weight.

Study Overview

• Status: Unknown
• Conditions: ECC; LBW Children

Detailed Description

Dental caries is on the top list of most widespread chronic diseases in addition to be a major public health issue. Dental caries is the single most common chronic childhood disease; it is 5 times more common than asthma, 7 times more common than hay fever and 14 times more common than chronic bronchitis. Deciduous tooth decay was ranked as the 12th most prevalent condition, affecting 560 million children in the 2015 Global Burden of Disease Study.

Low birth weight and premature birth are highly related to infant mortality, perinatal infections and the poor growth and development of children. Some risk groups have been identified, and attention should be focused on them so that preventive and health promotion measures are taken in an attempt to reverse this situation. One of these risk groups is composed of children born prematurely. Prematurity may be a predisposing factor for the development of caries.

There is a strong relationship between birth weight and infant mortality and morbidity and chronic diseases later in life. Many studies discussed the association between birth weight and dental caries however the results were conflicting. Knowledge of the association between low birth weight and the risk factors of ECC and the associated nutritional risk factors will improve the preventive and health promotion measures for this population.

• Study Type: Observational
• Enrollment (Anticipated): 80

Contacts and Locations

• Study Contact: Name: dina morad; Phone Number: 01150316543; Email: dina_farrag@dentistry.cu.edu.eg

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 1 year to 3 years (Child)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

healthy, children aged from 12 to 36 month.

Description

Inclusion Criteria:

• Healthy children.
• Children aged from 12 to 36 month.

Exclusion Criteria:

• Refusal of participation from the parents.
• Medically compromised children
• Major illness
• Child with special needs
• Any systemic disease that may affect caries experience.
• Any congenital deformity that may affect caries experience.

Study Plan

How is the study designed?

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort
group A; children with low birth weight
group B; children with normal birth weight

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
early childhood caries	Dental examination	1 year

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Nutritional risk factors	questionnaire	1 year

Collaborators and Investigators

• Sponsor: Cairo University
• Investigators: Study Director: Ola Omar, Professor of Pediatric Dentistry and Dental Public Health; Study Chair: Marwa Ali, Lecturer of Pediatric Dentistry and Dental Public Health

Publications and helpful links

General Publications

• da Silva Castro CR, de Sousa Cabral MBB, Mota ELA, Cangussu MCT, Vianna MIP. Analysis of the influence of low birth weight on the time of eruption of dental caries in children in early childhood. J Public Health Dent. 2019 Dec;79(4):292-297. doi: 10.1111/jphd.12322. Epub 2019 May 13.
• Masumo R, Birungi N, Bardsen A, Fadnes LT, Astrom AN. Impact of low birthweight on early childhood caries in 6-36 months old infants in Uganda: A cross-sectional study. Acta Odontol Scand. 2014 May;72(4):312-20. doi: 10.3109/00016357.2014.880189. Epub 2014 Jan 27.

Study record dates

Study Major Dates

• Study Start (Anticipated): August 1, 2020
• Primary Completion (Anticipated): June 1, 2021
• Study Completion (Anticipated): July 1, 2021

Study Registration Dates

• First Submitted: February 5, 2020
• First Submitted That Met QC Criteria: April 12, 2020
• First Posted (Actual): April 14, 2020

Study Record Updates

• Last Update Posted (Actual): July 15, 2020
• Last Update Submitted That Met QC Criteria: July 13, 2020
• Last Verified: July 1, 2020

More Information

Terms related to this study

• Keywords: premature birth; ECC
• Additional Relevant MeSH Terms: Body Weight; Birth Weight
• Other Study ID Numbers: ECC in LBW children

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No