Compare the Quadriceps Function of Adductor Canal Block Versus Femoral Nerve Block With Electromyography Following Total Knee Arthroplasty

Adductor canal block and femoral nerve block are the most commonly used nerve blocks for pain control after total knee arthroplasty. The block area for adductor canal is a sensory branch near the knee area, which can potentially reduce the effect of motor blockage of quadriceps muscle. We try to proof adductor canal block can reduce the pain level after surgery effectively and preserve the muscle power of quadriceps muscle. Therefore, the rehabilitation course can be reduced and further lowering the risks of falling and complications.

Study Overview

• Status: Completed
• Conditions: Quadriceps Function Monitored With Electromyography
• Intervention / Treatment: Procedure: Nerve block

• Study Type: Interventional
• Enrollment (Actual): 80
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Taiwan
  • Kaohsiung, Taiwan, 80145
    • Kaohsiung Municipal Ta-Tung Hospital

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 50 years to 100 years (Adult, Older Adult)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• Age at least 50 years old, not exceed 100 years old
• Diagnosed Primary Knee Osteoarthritis
• Accepted Total Knee Arthroplasty

Exclusion Criteria:

• Diagnosed Osteonecrosis
• Diagnosed inflammatory Arthritis、Rheumatoid Arthritis
• Accepted Revision Total Knee Arthroplasty
• Quadriceps muscle rupture, suture or repair history
• Neurological or orthopedic disorders that could affect quadriceps muscle power
• Allergy to amide anesthetics
• Patients who cannot obey or follow directions

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Double

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Adductor canal block group	Procedure: Nerve block; Two different nerve block types, Adductor canal block group and Femoral nerve block group
Experimental: Femoral nerve block group	Procedure: Nerve block; Two different nerve block types, Adductor canal block group and Femoral nerve block group

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Quadriceps muscle Electromyography voltage level change before and after nerve block	surface electromyography level	compare difference of Quadriceps muscle Electromyography voltage level 12 weeks after surgery,data were measured post operation day 1, day 2, day 5, 2 weeks, 6 weeks and 12 weeks

Collaborators and Investigators

• Sponsor: Kaohsiung Medical University Chung-Ho Memorial Hospital
• Investigators: Study Director: Hsuan-Ti Huang, M.D, Kaohsiung Medical University

Study record dates

Study Major Dates

• Study Start (Actual): February 24, 2021
• Primary Completion (Actual): October 18, 2021
• Study Completion (Actual): November 29, 2021

Study Registration Dates

• First Submitted: February 25, 2021
• First Submitted That Met QC Criteria: February 28, 2021
• First Posted (Actual): March 3, 2021

Study Record Updates

• Last Update Posted (Actual): March 2, 2022
• Last Update Submitted That Met QC Criteria: February 28, 2022
• Last Verified: February 1, 2021

More Information

Terms related to this study

• Other Study ID Numbers: KMUHIRB-F(I)-20200031

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No