- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT05205226
Local Radiotherapy for Residual Tumor Lesions During the First-line Treatment
January 11, 2022 updated by: Yongchang Zhang, Hunan Province Tumor Hospital
Efficacy and Safety of Local Radiotherapy for Residual Tumor Lesions During the First-line Treatment of Advanced Non-small Cell Lung Cancer: a Retrospective-real World Study
This study aimed to confirmed that local radiotherapy for residual lesions can significantly prolong the efficacy of chemotherapy combined with immunotherapy in the initial treatment of advanced non-small cell lung cancer.
Study Overview
Status
Completed
Conditions
Study Type
Observational
Enrollment (Actual)
636
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
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Hunan
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Changsha, Hunan, China, 410013
- Hunan Cancer Hospital
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years and older (Adult, Older Adult)
Accepts Healthy Volunteers
N/A
Genders Eligible for Study
All
Sampling Method
Probability Sample
Study Population
Patients with non driver mutation advanced non-small-cell lung cancer non driver mutation
Description
Inclusion Criteria:
- ≥18,Advanced Non-small Cell Lung Cancer Confirmed by Histopathology Patients received platinum-based chemotherapy combined with immunotherapy
Exclusion Criteria:
- EGFR/ALK/ROS1 driver gene mutation
- Chemotherapy only
- Concurrent radio-chemotherapy
- Surgery
- Single-agent immunotherapy
- No treatment information available
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Observational Models: Cohort
- Time Perspectives: Retrospective
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
PFS
Time Frame: January 2018 to June 2021
|
Progression free survival time
|
January 2018 to June 2021
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
RT
Time Frame: January 2018 to June 2021
|
radiotherapy control time
|
January 2018 to June 2021
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
January 2, 2018
Primary Completion (Actual)
June 5, 2021
Study Completion (Actual)
January 2, 2022
Study Registration Dates
First Submitted
January 11, 2022
First Submitted That Met QC Criteria
January 11, 2022
First Posted (Actual)
January 25, 2022
Study Record Updates
Last Update Posted (Actual)
January 25, 2022
Last Update Submitted That Met QC Criteria
January 11, 2022
Last Verified
January 1, 2018
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- SPLENDOR
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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