The Influence of Different Mood States and Emotions on the Physiologic, Metabolic, and Perceptual Responses to Feeding Before Exercise

March 17, 2025 updated by: Patrick Wilson, PhD, Old Dominion University
Many athletes anecdotally report modifying their nutritional intake before competition in order to avoid gut problems, but no studies have evaluated whether emotional state impacts tolerance to pre-exercise feeding. Therefore, this study will use movie clips (stressful, horror, and funny/amusing) to induce different mood states and emotions, which will be followed by ingestion of food before endurance running on a treadmill. In addition, metabolic and physiologic responses to mood induction will be evaluated.

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Estimated)

90

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

  • United States
    • Virginia
      • Norfolk, Virginia, United States, 23529
        • Recruiting
        • Human Performance Laboratory
        • Contact:

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 55 years (Adult)

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  1. Aged 18 to 55 years
  2. Able to run for 30 min at a moderate-to-vigorous intensity without stopping
  3. No diagnosis or signs/symptoms of cardiovascular disease (CVD) or metabolic disorders
  4. Currently physically active (at least 3 days/week of exercise at a moderate or higher intensity)
  5. No visual or hearing impairments interfering with ability to see and hear video clips
  6. No allergies to ingredients in Boost drink

Exclusion Criteria:

  1. Aged <18 or >55 years
  2. Unable to run for 30 min at a moderate-to-vigorous intensity without stopping
  3. A diagnosis or signs/symptoms of CVD or metabolic disorders
  4. Currently physically inactive (< 3 days/week of exercise at a moderate or higher intensity)
  5. Visual or hearing impairments interfering with ability to see and hear video clips
  6. Allergies to ingredients in Boost drink

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Basic Science
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Funny/Amusing Video Clips
Participants will watch 5-7-min video clips that are meant to be funny/amusing
Other: Funny/Amusing Video Clips
Participants watch 5-7 minutes of video clips that are funny/amusing in nature
Experimental: Horror/Scary Video Clips
Participants will watch 5-7-min video clips that are meant to be scary
Other: Horror/Scary Video Clips
Participants watch 5-7 minutes of video clips that are scary in nature
Experimental: Thrilling/Suspenseful Video Clips
Participants will watch 5-7-min video clips that are meant to be thrilling/suspenseful
Other: Thrilling/Suspenseful Video Clips
Participants watch 5-7 minutes of video clips that are thrilling/suspenseful in nature

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Total exercise gastrointestinal symptom burden
Time Frame: Total GI symptom burden over a 30-minute jogging/running protocol.
The severity of several gastrointestinal symptoms will be assessed on a validated 0-10 scale. Ratings will be collected every 5 minutes during a 30-minute treadmill jogging/running test. Scores from every 5-minute collection will be summed to calculate total GI symptom scores.
Total GI symptom burden over a 30-minute jogging/running protocol.
Change in emotion ratings
Time Frame: Change in emotion ratings between immediately pre-video and immediately post-video.
Anxiety, fear, happiness, amusement, disgust, sadness, and anger on a 0-9 Likert scale. Emotions will be assessed before watching video clips and immediately after watching video clips.
Change in emotion ratings between immediately pre-video and immediately post-video.

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Change over time in exercise heart rate
Time Frame: Heart rate will be measured throughout a 30-minute treadmill jogging/running test. Change over time will be evaluated using mixed ANOVA.
Heart rate will be measured with a chest-strap (Polar) monitor.
Heart rate will be measured throughout a 30-minute treadmill jogging/running test. Change over time will be evaluated using mixed ANOVA.
Substrate use
Time Frame: Carbohydrate and fat oxidation rates will be measured during the last 5 min of a 30-minute treadmill jogging/running test.
Carbohydrate and fat oxidation rates will be estimated from the volumes of oxygen consumption and carbon dioxide production during exercise
Carbohydrate and fat oxidation rates will be measured during the last 5 min of a 30-minute treadmill jogging/running test.
Feeling Scale
Time Frame: Ratings on the Feeling Scale will be measured at rest before watching video clips and throughout (every 5 min) a subsequent 30-minute treadmill jogging/running test.
The Feeling Scale is a bipolar numerical rating scale ranging from -5 to +5, with descriptors of "very bad" at -5, "neutral" at 0, and "very good" at +5.
Ratings on the Feeling Scale will be measured at rest before watching video clips and throughout (every 5 min) a subsequent 30-minute treadmill jogging/running test.
Fatigue Scale
Time Frame: Ratings on the Fatigue Scale will be measured at rest before watching video clips and throughout (every 5 min) a subsequent 30-minute treadmill jogging/running test.
The Fatigue Scale is Likert-type scale that ranges from 0 (Not Fatigued at All) to 10 (Total Fatigue).
Ratings on the Fatigue Scale will be measured at rest before watching video clips and throughout (every 5 min) a subsequent 30-minute treadmill jogging/running test.
Heart rate post-video
Time Frame: Heart rate will be recorded immediately after videos are viewed.
Heart rate will be measured with a chest-strap (Polar) monitor.
Heart rate will be recorded immediately after videos are viewed.

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Old Dominion University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

April 1, 2022

Primary Completion (Estimated)

December 1, 2025

Study Completion (Estimated)

December 31, 2025

Study Registration Dates

First Submitted

December 21, 2021

First Submitted That Met QC Criteria

January 20, 2022

First Posted (Actual)

February 1, 2022

Study Record Updates

Last Update Posted (Actual)

March 25, 2025

Last Update Submitted That Met QC Criteria

March 17, 2025

Last Verified

March 1, 2025

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 21-180

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

UNDECIDED

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

product manufactured in and exported from the U.S.

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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