Effect of Topical Application of Hyaluronic Acid on Stability of Immediate Loading Dental Implant in Posterior Maxilla

June 1, 2022 updated by: Mansoura University
Effect of Topical Application of Hyaluronic Acid on Stability of Immediate Loading Dental Implant in Posterior Maxilla

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

Patients were randomly divided into two groups:

Group I (Control group):

Ten implants were placed in posterior maxilla and immediately loaded.

Group II (Study group):

Ten implants were coated with HA before placement in posterior maxilla and immediately loaded.

Study Type

Interventional

Enrollment (Actual)

20

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Egypt
      • Mansoura, Egypt
        • Merna Elhadidi

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

16 years to 56 years (Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • Highly motivated patients with good oral hygiene.
  • Age 18 years or older.
  • Adequate alveolar bone volume at the implant site, at least 6mm in width and 15 mm in height.
  • Free from any parafunctional habits

Exclusion Criteria:

  • Patients suffering from any systemic or local disease that contraindicate implant placement or surgery.
  • Pregnancy.
  • Smokers.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Other
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Active Comparator: control
Each implant was placed into the prepared implant site.
Other: conventional implant placement
immediate placement of dental implant without application of hyaluronic acid on implant surface
Experimental: Hyaluronic acid
Each implant was placed after topical application of HA on its surface
Other: Hyaluronic acid
immediate placement of dental implant after topical application of hyaluronic acid on implant surface

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
implant stability
Time Frame: immediately after surgery
using radiofrequency analysis
immediately after surgery
implant stability
Time Frame: one month
using radiofrequency analysis
one month
implant stability
Time Frame: three months
using radiofrequency analysis
three months
implant stability
Time Frame: six months
using radiofrequency analysis
six months
bone density
Time Frame: three months
bone density around the implant is measured in cone beam computed tomography
three months

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
propping depth
Time Frame: six months
The distance between the gingival margin and the base of the pocket
six months
bleeding inex
Time Frame: six months
Modified sulcus bleeding index
six months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Mansoura University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

March 1, 2019

Primary Completion (Actual)

March 1, 2020

Study Completion (Actual)

March 1, 2020

Study Registration Dates

First Submitted

May 20, 2022

First Submitted That Met QC Criteria

June 1, 2022

First Posted (Actual)

June 3, 2022

Study Record Updates

Last Update Posted (Actual)

June 3, 2022

Last Update Submitted That Met QC Criteria

June 1, 2022

Last Verified

May 1, 2022

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 01010119

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

No

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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