Erector Spinae Plane Block Versus Quadratus Lumborum Block For Postoperative Analgesia After Abdominal Hysterectomy

Erector Spinae Plane Block Versus Quadratus Lumborum Block For Postoperative Analgesia After Abdominal Hysterectomy; A Randomized Comparative Study

The aim of this study is to compare the analgesic efficacy of erector spinae plane block and quadratus lumborum block after abdominal hysterectomy surgery and postoperative opioid consumption.

Study Overview

• Status: Completed
• Conditions: Anesthesia
• Intervention / Treatment: Procedure: peripheral nerve block

• Study Type: Interventional
• Enrollment (Actual): 64
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Egypt
  • Cairo, Egypt
    • Ain shams univerisity

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 36 years to 76 years (Adult, Older Adult)
• Accepts Healthy Volunteers: No

Description

Inclusion Criteria:

• Patients with American Society of Anesthesiologists (ASA) physical status 1-3.
• scheduled for abdominal hysterectomy surgery.

Exclusion Criteria:

• History of allergy to the medications used in the study.
• Contraindication to regional anesthesia as coagulopathy, local infection.
• Severe hepatic impairment (child C).
• Sever Renal dysfunction (creatinine clearance < 30).
• Psychiatric or mental disorder affecting patient ability to interpret VAS score.
• Body mass index (BMI) ≥ 40 or ≤ 18 kg/m2.
• ASA IV.
• Patient refusal.

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Supportive Care
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Double

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Active Comparator: ESPB; Erector Spinae Plane Block group	Procedure: peripheral nerve block; ultrasound guided nerve block
Active Comparator: QLB; Quadratus Lumborum Block group	Procedure: peripheral nerve block; ultrasound guided nerve block

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Post-operative pain	Post-operative pain severity assessed by visual analog scale (VAS) (range from 0-10., 0 no pain, 10 worst pain ).	24 hours

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Cumulative post-operative opioid consumption	opioid consumption	24 hours
The onset of 1st analgesic request	time needed for 1st request of rescue analgesia	24 hours

Other Outcome Measures

Outcome Measure	Measure Description	Time Frame
Incidence of complications	postoperative nausea and vomiting(PONV), hematoma, local anaesthetic toxicity (LAT)	24 hours

Collaborators and Investigators

• Sponsor: Ain Shams University

Study record dates

Study Major Dates

• Study Start (Actual): July 7, 2022
• Primary Completion (Actual): January 20, 2023
• Study Completion (Actual): February 10, 2023

Study Registration Dates

• First Submitted: September 13, 2022
• First Submitted That Met QC Criteria: September 13, 2022
• First Posted (Actual): September 15, 2022

Study Record Updates

• Last Update Posted (Actual): July 29, 2024
• Last Update Submitted That Met QC Criteria: July 26, 2024
• Last Verified: July 1, 2024

More Information

Terms related to this study

• Other Study ID Numbers: ASUKH1

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No