Performance of PLR as Predicting Preload Responsiveness (PLR)

May 21, 2023 updated by: Marc Kriege, MD, Johannes Gutenberg University Mainz

Evaluation of the Correct Performance and Knowledge About the Passive Leg Raise Test to Detect a Volume Reagibility in Critical Care Patients.

We aimed to establish current practice of correct application and interpretation of the PLR in critical care patients.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

The points of concern for PLR include the following: the indication and contraindication of PLR; the choice of initial position: starting from a semi-recumbent position or supine position for PLR; how to interpret and apply the changes of CO, blood pressure, and central venous pressure (CVP) to identify fluid response during PLR; and how to identify spontaneous variation and sympathetic stimulation during PLR.

Study Type

Observational

Enrollment (Actual)

292

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Germany
    • Rhineland-Palatinate
      • Mainz, Rhineland-Palatinate, Germany, D55131
        • Department of Anesthesiology,Prof. C. Werner, Universitätsmedizin of the JG University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult
  • Older Adult

Accepts Healthy Volunteers

N/A

Sampling Method

Non-Probability Sample

Study Population

All Critical care physicians

Description

Inclusion Criteria:

  • All Critical care physicians of different medical disciplines

Exclusion Criteria:

  • not completely responses

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
We aimed to establish current practice of correct application and interpretation of the PLR in critical care patients
Time Frame: through study completion, an average of Measurement in 5 Minutes
Application and Interpretation of correct effect size
through study completion, an average of Measurement in 5 Minutes

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Profession
Time Frame: < 10 Minutes
Profession of the respondents
< 10 Minutes
Measurement of cardiac output
Time Frame: < 10 Minutes
correct response of stroke volume
< 10 Minutes

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Johannes Gutenberg University Mainz

Investigators

  • Principal Investigator: Marc Kriege, University Medical Centre

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

December 1, 2021

Primary Completion (Actual)

January 31, 2022

Study Completion (Actual)

February 28, 2022

Study Registration Dates

First Submitted

May 11, 2023

First Submitted That Met QC Criteria

May 21, 2023

First Posted (Actual)

May 31, 2023

Study Record Updates

Last Update Posted (Actual)

May 31, 2023

Last Update Submitted That Met QC Criteria

May 21, 2023

Last Verified

May 1, 2023

More Information

Terms related to this study

Keywords

Other Study ID Numbers

  • JohannesGUVT

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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