Matcha Green Tea Effects at Rest and During Moderate-intensity Exercise in Females

Effects of Matcha Green Tea on Heart Rate Variability, Substrate Oxidation and Cardiovascular Response at Rest and During Moderate-intensity Exercise in Females

Intake of the green tea catechin epigallocatechin (EGCG) increased fat oxidation during walking. It is also known to reduce blood pressure and improve body composition. This research will expand the insight on the effects by Matcha green tea supplementation and address the effects on heart rate variability, substrate oxidation at rest, and cardiovascular responses at rest in addition to metabolic and physiologic responses for a 1-hr walk in healthy females.

Study Overview

• Status: Recruiting
• Conditions: No Condition
• Intervention / Treatment: Dietary supplement: Placebo; Dietary supplement: Matcha green tea

Detailed Description

Intake of the catechin epigallocatechin (EGCG) increased fat oxidation during walking. It is also known to reduce blood pressure and improve body composition. EGCG is the most abundant and potent bioactive compound (50-80% of the total catechin content) found in Matcha green tea (MGT) and is usually consumed as a drink or in a capsulated from unfermented tea leaves. MGT polyphenols have antioxidant and anti-inflammatory properties, providing numerous health benefits, such as the reduced risk of type 2 diabetes and obesity. MGT supplementation (3g over a 24hr period) has been shown to enhance fat oxidation during 30-min brisk walking as well as lower respiratory exchange ratio in females. Understanding the effectiveness of the bioactive compounds found in natural food sources in improving human health is key to informing the general population and the public health policies preceding them; the daily consumption of drinks and food naturally high in EGCG content could be recommended as an essential part of a healthy lifestyle. This research will expand the insight on Matcha green tea supplementation address the effect on heart rate variability, substrate oxidation at rest, and cardiovascular responses at rest in addition to metabolic and physiologic responses for a 1-hr walk in healthy females.

• Study Type: Interventional
• Enrollment (Estimated): 14
• Phase: Not Applicable

Contacts and Locations

• Study Contact: Name: Mark E Willems, PhD; Phone Number: +4401243816468; Email: m.willems@chi.ac.uk
• Study Contact Backup: Name: Charles Green, PhD; Email: c.green@chi.ac.uk

Study Locations

• United Kingdom
  • Chichester, United Kingdom
    • Recruiting
    • University of Chichester
    • Contact: Mark Willems
  • West Sussex
    • Chichester, West Sussex, United Kingdom, PO19 6PE
      • Recruiting
      • Mark Willems
      • Contact: Charles Green, PhD; Email: c.green@chi.ac.uk
      • Contact: Mark E Willems, PhD; Phone Number: 07807604749; Email: m.willems@chi.ac.uk

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult
• Accepts Healthy Volunteers: Yes

Description

Inclusion Criteria:

• healthy
• non-smokers
• not taking any supplements
• no known allergy to green tea

Exclusion Criteria:

• smokers
• known high blood pressure
• on medication

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Basic Science
• Allocation: Randomized
• Interventional Model: Crossover Assignment
• Masking: Single

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Placebo; Participants will be supplemented with a placebo.	Dietary supplement: Placebo; This is the condition with the placebo
Experimental: Matcha green tea; Participants will be supplemented with Matcha green tea.	Dietary supplement: Matcha green tea; This is the condition with the Matcha green tea

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Heart rate variability	Measurement of root mean square of standard deviation of RR intervals	Three weeks
Carbohydrate oxidation	Measurement of carbohydrate oxidation in grams/minute	Three weeks
Fat oxidation	Measurement of fat oxidation in grams/minute	Three weeks
Cardiac output	Measurement of cardiac output in liters per minute	Three weeks
Stroke volume	Measurement of stroke volume in milliliters	Three weeks
Total peripheral resistance	Measurement of total peripheral resistance in (mmHg x min) / mL	Three weeks

Collaborators and Investigators

• Sponsor: University of Chichester
• Investigators: Principal Investigator: Mark E Willems, University of Chichester

Study record dates

Study Major Dates

• Study Start (Actual): March 3, 2023
• Primary Completion (Estimated): July 26, 2023
• Study Completion (Estimated): August 15, 2023

Study Registration Dates

• First Submitted: May 17, 2023
• First Submitted That Met QC Criteria: May 26, 2023
• First Posted (Actual): May 31, 2023

Study Record Updates

• Last Update Posted (Actual): May 31, 2023
• Last Update Submitted That Met QC Criteria: May 26, 2023
• Last Verified: May 1, 2023

More Information

Terms related to this study

• Other Study ID Numbers: 22231905455

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No