Head and Neck Paragangliomas: A 16-year Experience of a University Hospital in Turkey

The aim of the study is to examine the head and neck paraganglioma cases treated in Pamukkale University hospital between 2007-2023 and improve our understanding of these cases and contribute to the knowledge surrounding head and neck paragangliomas.

Study Overview

• Status: Completed
• Conditions: Head and Neck Paraganglioma

Detailed Description

39 patients were selected and analyzed retrospectively. Demographic informations, complaints at the time of admission, radiological examinations, paraganglioma types, stages, postoperative complications, and relapsed cases were recorded.Preoperative staging plays a crucial role in surgical planning and predicting potential intraoperative complications. In such cases, combination therapy alongside surgery may improve treatment outcomes.

• Study Type: Observational
• Enrollment (Actual): 39

Contacts and Locations

Study Locations

• Turkey
  • Denizli, Turkey, 20070
    • Pamukkale University

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child; Adult; Older Adult
• Accepts Healthy Volunteers: No

• Sampling Method: Probability Sample

Study Population

Patients who underwent head and neck surgeries at Pamukkale University Hospital between 2007 and 2023, resulting in a histopathological diagnosis of paraganglioma

Description

Inclusion Criteria:

• Histopathological diagnosis of carotid paraganglioma
• Histopathological diagnosis of vagal paraganglioma
• Histopathological diagnosis of jugular paraganglioma
• Histopathological diagnosis of tympanic paraganglioma

Exclusion Criteria:

-Inadequate information in files

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Postoperative recurrence	Incidence of recurrences after the surgery	may 2023-june 2023
Postoperative nerve paralysis	Incidence of facial, vagus, hypoglossus, accesorius nerve paralysis after surgery	may 2023-june 2023

Collaborators and Investigators

• Sponsor: Pamukkale University
• Investigators: Principal Investigator: Fazıl N Ardıç, MD, Pamukkale University

Study record dates

Study Major Dates

• Study Start (Actual): June 30, 2023
• Primary Completion (Actual): July 5, 2023
• Study Completion (Actual): July 5, 2023

Study Registration Dates

• First Submitted: June 30, 2023
• First Submitted That Met QC Criteria: July 11, 2023
• First Posted (Actual): July 12, 2023

Study Record Updates

• Last Update Posted (Actual): September 15, 2023
• Last Update Submitted That Met QC Criteria: September 14, 2023
• Last Verified: September 1, 2023

More Information

Terms related to this study

• Keywords: Paraganglioma; glomus
• Additional Relevant MeSH Terms: Neoplasms by Histologic Type; Neoplasms; Neuroectodermal Tumors; Neoplasms, Germ Cell and Embryonal; Neoplasms, Nerve Tissue; Neuroendocrine Tumors; Paraganglioma
• Other Study ID Numbers: 13

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No