Natural Course of Homocysteine After Uneventful Total Joint Arthroplasty

February 9, 2024 updated by: Cemil Burak DEMİRKIRAN, Bezmialem Vakif University

The goal of this observational study is to asses the natural course of blood homocysteine levels in patients who underwent primary total joint arthroplasty surgery. The main question[s] it aims to answer are:

  • İs homocysteine a good marker for determining periprosthetic joint infection ?
  • İs homocysteine more sensitive marker for periprosthetic joint infections ?

Study Overview

Status

Not yet recruiting

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Estimated)

80

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Turkey
      • Istanbul, Turkey, 34140
        • Bezmialem Vakif University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

Yes

Sampling Method

Probability Sample

Study Population

Healty volunteers who have undergone uneventful primary total joint arthroplasty

Description

Inclusion Criteria:

  • People who have undergone Total Knee Arthroplasty operation
  • People who have undergone Total Hip Arthroplasty operation

Exclusion Criteria:

  • People who have undergone total knee arthroplasty operation and developed a periprosthetic joint infection
  • People who have undergone total hip arthroplasty operation and developed a periprosthetic joint infection

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Arthroplasty Patients
Only one group that consist patients who underwent primary total joint arthroplasty
Diagnostic test: Blood works for homocysteine levels
In a single patient group of 80 people, the natural course of homocysteine after total joint arthroplasty will be examined by blood work analyzes at the 1,2,3,4 and 6th weeks after operation

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Homocysteine
Time Frame: 6 months
Homocysteine levels in patient blood works
6 months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Bezmialem Vakif University

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

April 10, 2024

Primary Completion (Estimated)

September 10, 2025

Study Completion (Estimated)

September 10, 2025

Study Registration Dates

First Submitted

August 5, 2023

First Submitted That Met QC Criteria

August 5, 2023

First Posted (Actual)

August 14, 2023

Study Record Updates

Last Update Posted (Actual)

February 12, 2024

Last Update Submitted That Met QC Criteria

February 9, 2024

Last Verified

February 1, 2024

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • cbdemirkan

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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