Preoperative BNP and MINS in AAA Open Repair
November 15, 2023 updated by: Sung Yeon Ham, Gangnam Severance Hospital
Prognostic Impact of Preoperative B-type Natriuretic Peptide for Predicting Myocardial Injury After Non-cardiac Surgery in Patients Who Underwent Open Repair for Abdominal Aortic Aneurysm: a Retrospective Study
The aim of this study was to investigate whether preoperative B-type natriuretic peptides serves as an independent predictor of myocardial injury after non-cardiac surgery (MINS) in abdominal aortic aneurysm open repair.
Study Overview
Status
Active, not recruiting
Conditions
Intervention / Treatment
Detailed Description
The incidence of MINS was compared between the lower BNP and higher BNP groups, and a stepwise logistic regression analysis was performed to evaluate the predictors for MINS.
Study Type
Observational
Enrollment (Actual)
198
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
-
Seoul, Korea, Republic of
- Gangnam Severance Hospital
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- Adult
- Older Adult
Accepts Healthy Volunteers
No
Sampling Method
Probability Sample
Study Population
patients who underwent AAA open repair
Description
Inclusion Criteria:
patients who underwent open repair with AAA from September 2010 to October 2021
Exclusion Criteria:
- Ruptured AAA
- Traumatic aortic injury
- Absence of troponin-T value within 30 days of surgery
- Diagnosis of elevation of troponin-T due to non-ischemic cause (ex: sepsis, pulmonary embolism, atrial fibrillation, cardioversion, etc.)
- Insufficient medical records
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
Cohorts and Interventions
Group / Cohort |
Intervention / Treatment |
|---|---|
|
Lower BNP
preoperative Lower BNP
|
preoperative BNP value
|
|
Higher BNP
preoperative higher BNP
|
preoperative BNP value
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
MINS
Time Frame: 30 days after surgery
|
MINS is defined as an elevated Troponin-T within 30 days of surgery.
The patients were divided into two groups based on their preoperative BNP levels, and the incidence of MINS was compared between the two groups.
|
30 days after surgery
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
January 1, 2022
Primary Completion (Actual)
March 30, 2023
Study Completion (Estimated)
July 6, 2024
Study Registration Dates
First Submitted
October 6, 2023
First Submitted That Met QC Criteria
October 12, 2023
First Posted (Actual)
October 18, 2023
Study Record Updates
Last Update Posted (Estimated)
November 17, 2023
Last Update Submitted That Met QC Criteria
November 15, 2023
Last Verified
November 1, 2023
More Information
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.