Silent Lumbar Disc Herniation Syndrome

LDH is a common phenomenon that is often described in association with various pathological processes affecting the neuromuscular and locomotor systems. It is not only associated with pathology but it can also be observed in healthy individuals with no evidence of any dysfunction. Since LDH is observed in such a large percentage of healthy subjects, it is probably more appropriate to perceive it as a physiological phenomenon with silent clinical biomechanical changes

Study Overview

• Status: Recruiting
• Conditions: Disc Herniation
• Intervention / Treatment: Other: Physical therapy

Detailed Description

An observational study will be conducted on 180 individuals without any back or lower extremity symptoms. Individuals who agree to participate in the study will be divided into 3 groups based on their MRI findings. Group 1 (silent disc herniation group): has LDH and root compression confirmed by the MRI but has no back or lower extremity symptoms. Group 2 (had a history of disc herniation with an improvement of their symptoms after receiving physical therapy intervention): has LDH and root compression confirmed by the MRI but has no back or lower extremity symptoms. Group 3 (control group): absence of LDH and root compression confirmed by the MRI has no back or lower extremity symptoms. The isokinetic peak torque for knee and ankle muscles and the H reflex will be assessed for all the individual investigating the influence of silent LDH on the isokinetic parameters and the H-reflex of the lower extremity may help in better guiding for lower extremity screening to identify individuals at risk for lower extremity injuries. It is hoped that clinicians will incorporate such information to understand the importance of confirming the improvemnt obtained from the physical therapy intervention with an MRI before discharging the patients to reduce the risk of recurrence……………………………………………………………………………..…………………………………………………………………………………………………………………..

• Study Type: Observational
• Enrollment (Estimated): 180

Contacts and Locations

Study Locations

• Egypt
  • Giza, Egypt, 12556
    • Recruiting
    • Faculty of Physical Therapy
    • Contact: Abeer Farag, PhD; Phone Number: 01063044443; Email: abeerfarag22@gmail.com

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult
• Accepts Healthy Volunteers: Yes

• Sampling Method: Non-Probability Sample

Study Population

A convenience sample of 180 adult males with a mean age of 40-50 years will be recruited to participate in the study. Inclusion criteria for the study groups (Group 1 and 2) LDH and root compression with no back or lower extremity symtoms. Inclusion criteria for the control group (Group 3) absence of LDH and root compression, no back or lower extremity symptoms. Exclusion criteria: Any previous history that would affect the alignment or the motion to lower extremity joints as fractures or surgery. Any fixed deformity True leg length discrepancy (>5mm).Any medical condition affecting peripheral nerves as diabetes mellitus.Any neuromuscular dysfunction and vestibular disorder.Sacroiliac pain or dysfunction low back pain.Radicular or referred or radiating pain Previous lower extremity injury

Description

Inclusion Criteria:

• Inclusion criteria patients with LDH and root compression with no back or lower extremity symptoms.

Exclusion Criteria:

• Any previous history that would affect the alignment or the motion to lower extremity joints as fractures or surgery.

Any fixed deformity True leg length discrepancy (>5mm). Any medical condition affecting peripheral nerves as diabetes mellitus. Any neuromuscular dysfunction and vestibular disorder.Sacroiliac pain or dysfunction low back pain.

Radicular or referred or radiating pain Previous lower extremity injury

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
physical therapy; core stability exercise	Other: Physical therapy; ultrasound for 5 minutes,Tens and hot packs for 20 minutes, back exercise

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
MRI of lumbar disc	presence or absence of disc herniation will be confirmed by MRI	three months

Collaborators and Investigators

• Sponsor: Noha Khaled Shoukry

Study record dates

Study Major Dates

• Study Start (Actual): February 1, 2023
• Primary Completion (Estimated): September 1, 2024
• Study Completion (Estimated): September 1, 2024

Study Registration Dates

• First Submitted: June 4, 2024
• First Submitted That Met QC Criteria: June 9, 2024
• First Posted (Actual): June 11, 2024

Study Record Updates

• Last Update Posted (Actual): June 11, 2024
• Last Update Submitted That Met QC Criteria: June 9, 2024
• Last Verified: June 1, 2024

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Musculoskeletal Diseases; Pathological Conditions, Anatomical; Spinal Diseases; Bone Diseases; Hernia; Intervertebral Disc Displacement
• Other Study ID Numbers: PCU

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: UNDECIDED

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No