- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT06808659
Effects of Neural Mobilization and Stretching in Piriformis Syndrome
January 29, 2025 updated by: Rabia Khan, Bahria University
Comparative Effects of Neural Mobilization of Sciatic Nerve Versus Stretching Among Patients With Piriformis Syndrome
This study compares the effects of piriformis stretching and neural mobilization of the sciatic nerve in individuals with piriformis syndrome, a condition that is frequently characterized by hip and buttock pain and discomfort brought on by the piriformis muscle compressing the sciatic nerve.
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Detailed Description
In a study involving 40 patients diagnosed with sciatica, researchers aimed to investigate whether neural mobilization of the sciatic nerve or stretching of the piriformis muscle was more effective in treating piriformis syndrome.
The patients were divided into two groups, each containing 20 individuals.
Group A underwent neural mobilization therapy, while Group B performed piriformis muscle stretches, with both groups receiving treatment three times a week for two weeks.
Assessments, including Visual Analog Scale (VAS) for pain, hip range of motion (ROM) in flexion, abduction, and external rotation, as well as the FAIR test, were conducted before and after the interventions.
Study Type
Interventional
Enrollment (Actual)
40
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
Sindh
-
Karachi, Sindh, Pakistan, 74700
- Isra Institute of Rehabilitation Sciences
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- Adult
- Older Adult
Accepts Healthy Volunteers
Yes
Description
Inclusion Criteria:
- Positive lasegue sign
- Positive piriformis sign
- Tenderness at sciatic notch (over piriformis muscle).
Exclusion Criteria:
• Prior surgery of lumbar spine (laminectomy)
- Unrecognized pelvic fracture
- Known case of renal stones
- Disc herniation in lumbar spine
- Myositis ossificans of piriformis muscle.
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: None (Open Label)
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
|---|---|
|
Experimental: Group A / Sciatic Nerve Mobilization
Sciatic Nerve Mobilization was given to group A participants.
|
A total of 20 patients were selected in Group A received neural mobilization of sciatic nerves treatment for 3 days a week for 2 weeks
Other Names:
|
|
Experimental: Group B / Piriformis Muscle Stretching
Piriformis Muscles was stretched in group B participants.
|
A total of 20 patients were selected in Group B received stretching of piriformis muscle treatment for 3 days a week for 2 weeks
Other Names:
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Pain Reduction
Time Frame: 2 weeks
|
Two different interventions were applied in groups after which pain was recorded before and after through visual analogue scale.
Highest score means high level of pain and lower score refers to low pain.
Maximum score 9 was reported pre study and minmum score 2 was reported after study by both groups on average.
|
2 weeks
|
|
Increase Range of Motion
Time Frame: 2 weeks
|
Through neural mobilization and piriformis stretching renage of motion was assessed through inclino meter before and after study
|
2 weeks
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Investigators
- Principal Investigator: Rabia Khan, Masters of Science
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
General Publications
- Danazumi MS, Yakasai AM, Ibrahim AA, Shehu UT, Ibrahim SU. Effect of integrated neuromuscular inhibition technique compared with positional release technique in the management of piriformis syndrome. J Osteopath Med. 2021 May 31;121(8):693-703. doi: 10.1515/jom-2020-0327.
- Shahzad M, Rafique N, Shakil-Ur-Rehman S, Ali Hussain S. Effects of ELDOA and post-facilitation stretching technique on pain and functional performance in patients with piriformis syndrome: A randomized controlled trial. J Back Musculoskelet Rehabil. 2020;33(6):983-988. doi: 10.3233/BMR-181290.
- Ahmad Siraj S, Dadgal R. Physiotherapy for Piriformis Syndrome Using Sciatic Nerve Mobilization and Piriformis Release. Cureus. 2022 Dec 26;14(12):e32952. doi: 10.7759/cureus.32952. eCollection 2022 Dec.
- Othman IK, Raj NB, Siew Kuan C, Sidek S, Wong LS, Djearamane S, Loganathan A, Selvaraj S. Association of Piriformis Thickness, Hip Muscle Strength, and Low Back Pain Patients with and without Piriformis Syndrome in Malaysia. Life (Basel). 2023 May 18;13(5):1208. doi: 10.3390/life13051208.
- Hu YE, Ho GWK, Tortland PD. Deep Gluteal Syndrome: A Pain in the Buttock. Curr Sports Med Rep. 2021 Jun 1;20(6):279-285. doi: 10.1249/JSR.0000000000000848.
- Burke CJ, Walter WR, Adler RS. Targeted Ultrasound-Guided Perineural Hydrodissection of the Sciatic Nerve for the Treatment of Piriformis Syndrome. Ultrasound Q. 2019 Jun;35(2):125-129. doi: 10.1097/RUQ.0000000000000360.
- Ankar P, Ratnani GR, Ramteke SU, Jaiswal PR. Effect of Neuromuscular Training and Neurodynamic Solutions for Asymptomatic Prolapsed Intervertebral Disc and Coexisting Piriformis Syndrome in a 19-Year-Old: A Comprehensive Case Report. Cureus. 2024 Jan 27;16(1):e53050. doi: 10.7759/cureus.53050. eCollection 2024 Jan.
Helpful Links
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
May 2, 2018
Primary Completion (Actual)
November 10, 2018
Study Completion (Actual)
December 28, 2018
Study Registration Dates
First Submitted
November 29, 2024
First Submitted That Met QC Criteria
January 29, 2025
First Posted (Actual)
March 25, 2025
Study Record Updates
Last Update Posted (Actual)
March 25, 2025
Last Update Submitted That Met QC Criteria
January 29, 2025
Last Verified
January 1, 2025
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- IERC/IIRS-IU-KC/18/005
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
NO
IPD Plan Description
Confidentiality
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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