Impact of a Structured Therapeutic Education Session on the Practice of Adapted Physical Activity in Chronic Inflammatory Bowel Diseases (ETAP-MICI)

Chronic inflammatory bowel diseases (IBD; including Crohn's disease and ulcerative colitis) significantly impact patients' quality of life. Among non-pharmacological therapies, adapted physical activity (APA) has demonstrated its beneficial impact, particularly on fatigue, anxiety, digestive symptoms, and the overall quality of life of patients with IBD.

The real-world implementation of APA remains insufficient, primarily due to limited patient adherence to this prescription.

Patient therapeutic education (PTE) represents a potentially powerful lever for promoting engagement in APA by addressing barriers related to a lack of awareness (fear of symptom worsening) and lack of motivation. No dedicated study has specifically evaluated the effect of targeted PTE sessions on adherence to physical activity in IBD.

The objective of the present feasibility study will be to determine whether a single therapeutic education session focused on the digestive and systemic benefits of APA has an impact on the rate of physical activity practice in the medium term among patients with IBD in clinical remission for at least 3 months.

Study Overview

• Status: Recruiting
• Conditions: Chronic Inflammatory Bowel Disease
• Intervention / Treatment: Diagnostic test: Inflammatory Bowek Disk Questionnaires; Other: Short-International Physical Activity Questionnaries

• Study Type: Observational
• Enrollment (Estimated): 71

Contacts and Locations

• Study Contact: Name: Cyrielle GILLETTA, MD; Phone Number: +33 05 61 31 22 31; Email: gilletta.c@chu-toulouse.fr

Study Locations

• France
  • Toulouse, France, 31059
    • Recruiting
    • Service de Gastro-Entérologie, CHU Toulouse, Hôpital Rangueil, 1 avenue Jean Poulhès
    • Contact: Emeline Muller; Phone Number: +33 05 61 77 87 07; Email: muller.E@chu-toulouse.Fr

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: No

• Sampling Method: Non-Probability Sample

Study Population

patients with chronic inflammatory bowel disease in clinical remission (Crohn's disease or ulcerative colitis)

Description

Inclusion Criteria:

• Confirmed diagnosis of Inflammatory Bowel Disease
• Crohn's disease in clinical remission (defined by a Harvey Bradshaw Index ≤ 5) or ulcerative colitis in clinical remission (defined by a Mayo score < 3 and no subscore > 1) for at least 3 months
• Social Security coverage

Exclusion Criteria:

• Pregnant or breastfeeding woman
• Patient under legal guardianship
• Cardiovascular or rheumatic conditions contraindicating participation in sports
• Neurological conditions with residual deficits contraindicating participation in sports
• Refusal or inability to consent to participation

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
patients with chronic inflammatory bowel disease; patients with chronic inflammatory bowel disease in clinical remission	Diagnostic test: Inflammatory Bowek Disk Questionnaires; Patients will be asked to complete the questionnaires regarding bowel inflammation at enrollment, 6 months later, and 12 months later.; Other: Short-International Physical Activity Questionnaries; Patients will be asked to complete the physical activity questionnaire 6 months later and 12 months later.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Effectiveness of therapeutic education intervention on physical activity practice	Measure the amount of metabolic equivalent or MET/Week (Metabolic Equivalent Task) at 12 months, based on the short-IPAQ questionnaire assessing physical activities reported by the patient over the last 7 days.	12 months after the inclusion

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
study the impact on quality of life at 6 months	measure of quality of life with the IBD disk questionnaires answers at 6 months	6 months after the inclusion
Study the impact on quality of life in 12 months	measure of quality of life with the IBD disk questionnaires answers at 12 months	12 months after the inclusion
study the impact on fatigue reported at 6 months	Measure of fatigue reported according to one of the items of the IBD Disk questionnaire at 6 months	6 months after the inclusion
study the impact on fatigue reported at 12 months	Measure of fatigue reported according to one of the items of the IBD Disk questionnaire at 12 months	12 months after the inclusion
study the correlation between increased overall muscle strength and improved quality of life	Measurement of estimated muscle strength using a hand grip test before and after intervention as part of annual malnutrition screening and response to the quality of life questionnaire	12 months after the inclusion
Study of the impact on the evolution of IBD activity at 6 months	measurement of clinical activity in chronic inflammatory bowel disease at 6 months	6 months after the inclusion
Study of the impact on the evolution of IBD activity at 12 months	measurement of clinical activity in chronic inflammatory bowel disease at 12 months	12 months after the inclusion
study the impact on the monitoring of the prescription of adapted physical activity	Monitoring of the APA prescription estimated according to the proportion of patients who completed at least 12 APA sessions (i.e. 1 weekly session for 3 months) and the average number of APA sessions completed.	12 months after the inclusion

Collaborators and Investigators

• Sponsor: University Hospital, Toulouse

Study record dates

Study Major Dates

• Study Start (Actual): February 10, 2026
• Primary Completion (Estimated): August 10, 2027
• Study Completion (Estimated): February 10, 2029

Study Registration Dates

• First Submitted: December 12, 2025
• First Submitted That Met QC Criteria: December 12, 2025
• First Posted (Actual): December 26, 2025

Study Record Updates

• Last Update Posted (Actual): February 13, 2026
• Last Update Submitted That Met QC Criteria: February 10, 2026
• Last Verified: February 1, 2026

More Information

Terms related to this study

• Keywords: physical activity; ulcerative colitis; crohn disease
• Additional Relevant MeSH Terms: Intestinal Diseases; Digestive System Diseases; Gastrointestinal Diseases; Colonic Diseases; Gastroenteritis; Inflammatory Bowel Diseases; Colitis; Behavior; Colitis, Ulcerative; Crohn Disease; Motor Activity
• Other Study ID Numbers: RC31/25/0588; ID-RCB (Other Identifier: 2023-A01756-39)

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No