Could Computerized Tomography be an Alternative to Colonoscopies for Screening for Colorectal Cancer?

January 6, 2026 updated by: Mucahit UNAL, Bilecik Seyh Edebali Universitesi

Could Computerized Tomography (CT) Scans be Used as an Alternative to Colonoscopies for Colorectal Cancer Screenings?

The aim of this observational study is to investigate whether computed tomography can be used as an alternative to colonoscopy in colon cancer screening. The main question the study aims to answer is:

Can colon cancer screening be performed as effectively with computed tomography as with colonoscopy?

Participants in the colon cancer screening group will be divided into two groups: those who underwent colonoscopy and those who underwent computed tomography. The screening effectiveness of the two methods will be compared.

Study Overview

Status

Active, not recruiting

Conditions

Study Type

Observational

Enrollment (Estimated)

600

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Turkey (Türkiye)
    • Bilecik
      • Bilecik, Bilecik, Turkey (Türkiye), 11000
        • Bilecik Seyh Edebali University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Sampling Method

Probability Sample

Study Population

CT scans and colonoscopies performed on patients aged 50-70 at Bilecik Research and Training Hospital between January 1, 2023, and December 31, 2024, will be examined.

Description

Inclusion Criteria:

  • All participants aged 50-70 who have undergone colonoscopy screening
  • All participants aged 50-70 who have undergone abdominal computed tomography

Exclusion Criteria:

- The patient has a history of colon cancer

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
colonscopy
participant screened by colonoscopy
tomography
participant screened by tomography

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
polyp/cancer incidance
Time Frame: when the pathology results are available after a colonoscopy or when the report is written after a CT scan through study completion, an average of 2 years
Number of patients with polyps and cancer detected by screening
when the pathology results are available after a colonoscopy or when the report is written after a CT scan through study completion, an average of 2 years

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Bilecik Seyh Edebali Universitesi

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

July 15, 2025

Primary Completion (Estimated)

March 1, 2026

Study Completion (Estimated)

September 1, 2026

Study Registration Dates

First Submitted

December 21, 2025

First Submitted That Met QC Criteria

January 6, 2026

First Posted (Actual)

January 15, 2026

Study Record Updates

Last Update Posted (Actual)

January 15, 2026

Last Update Submitted That Met QC Criteria

January 6, 2026

Last Verified

January 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • E-10333602-050.04-339197

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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