Anatomical Assessment of Orbital Contents on Imaging (EACOI) (EACOI)

Anatomical Assessment of Orbital Contents on Imaging

This is a single-center retrospective study based on existing data. The study focuses on the anatomical content of the orbit, and in particular the anatomy of the oculomotor muscles in the orbit, which are involved in eye movements. There are 6 of these muscles, with the superior, inferior, medial and lateral rectus muscles, and the superior and inferior oblique muscles in each orbit. The study also covers the anatomy of the optic nerve and orbital fat.

Knowledge of the anatomy and biometry of the oculomotor muscles, and of methods for assessing these muscles, has implications for clinical, medical and surgical practice.

Study Overview

• Status: Recruiting
• Conditions: Anatomical Study

• Study Type: Observational
• Enrollment (Estimated): 190

Contacts and Locations

• Study Contact: Name: Brieg DISSAUX; Phone Number: +33 02983408034; Email: brieg.dissaux@chu-brest.fr

Study Locations

• France
  • Brest, France, 29609
    • Recruiting
    • CHU Brest

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: Yes

• Sampling Method: Non-Probability Sample

Study Population

Patients in the general population who underwent brain imaging (CT or MRI) in the medical imaging department

Description

Inclusion Criteria:

• Patients over 18
• No opposition to the participation
• Usable imaging test

Exclusion Criteria:

• Refusal to participate

Study Plan

How is the study designed?

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort
Oculomotor muscles study
Intraorbital content

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Intra- and inter-observer reproducibility of oculomotor muscle anatomical criteria in imaging	Evaluate the reproducibility of different oculomotor muscle measurements, such as volume (mm3), surface (mm2) or two-dimensional measurements (mm). Differences to the mean. Intraclass correlation coefficient (ICC).	1 year.

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Reproducibility of measurements of optic nerve size and orbital fat in imaging	Evaluate the reproducibility of different measurements to assess the size of the optic nerve (volume (mm3), surface (mm2), two-dimensional measurement (mm) and intra-orbital fat (mm3). Dfference to the mean. Intraclass correlation coefficient (ICC).	1 year.

Collaborators and Investigators

• Sponsor: University Hospital, Brest

Study record dates

Study Major Dates

• Study Start (Actual): May 1, 2024
• Primary Completion (Estimated): June 30, 2026
• Study Completion (Estimated): June 30, 2026

Study Registration Dates

• First Submitted: June 3, 2025
• First Submitted That Met QC Criteria: January 16, 2026
• First Posted (Actual): January 22, 2026

Study Record Updates

• Last Update Posted (Actual): January 22, 2026
• Last Update Submitted That Met QC Criteria: January 16, 2026
• Last Verified: January 1, 2025

More Information

Terms related to this study

• Other Study ID Numbers: 29BRC23.0315 - EACOI

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: UNDECIDED

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No