Pattern of Treatment and Outcomes of Locally Advanced Rectal Carcinoma

January 14, 2026 updated by: Azhar Abdelgaber Moez Abdelraheem, Sohag University

Pattern of Treatment and Outcomes of Locally Advanced Rectal Carcinoma : a Retrospective Study

the study will discuss different pattern of treatment and the outcomes of locally advanced rectal carcinoma as a retrospective study.

The study will be conducted at Department of Clinical Oncology, Sohag University Hospital and Sohag Cancer center, Sohag, Egypt.

including patients diagnosed and treated between 2018 and 2025. and the data will be collected from reports .

Study Overview

Status

Not yet recruiting

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Estimated)

100

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Sampling Method

Non-Probability Sample

Study Population

The study will be conducted at Department of Clinical Oncology, Sohag University Hospital and Sohag Cancer center, Sohag, Egypt.

Description

Inclusion Criteria:

  • patients who were more than18 years old at time of diagnosis.
  • Patients with histologically confirmed rectal carcinoma.
  • Stage II-III (locally advanced) disease at initial diagnosis.

Exclusion Criteria:

  • Patients with distant metastasis at presentation.
  • Patients diagnosed with double malignancy.
  • Patients with incomplete medical records.
  • Organ failure

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Estimation of overall survival (OS ).
Time Frame: 2018 _ 2025
2018 _ 2025
Estimation of Response rate .
Time Frame: 2018-2025
2018-2025
Estimation of disease-free survival (DFS) .
Time Frame: 2018-2025
2018-2025

Secondary Outcome Measures

Outcome Measure
Time Frame
treatment-related toxicity: (graded by CTCAE v5).
Time Frame: 2018-2025
2018-2025

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Sohag University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

March 1, 2026

Primary Completion (Estimated)

July 1, 2026

Study Completion (Estimated)

October 1, 2026

Study Registration Dates

First Submitted

November 27, 2025

First Submitted That Met QC Criteria

January 14, 2026

First Posted (Actual)

January 23, 2026

Study Record Updates

Last Update Posted (Actual)

January 23, 2026

Last Update Submitted That Met QC Criteria

January 14, 2026

Last Verified

November 1, 2025

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • Soh-Med--25-11-2MS

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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