Clinical Characteristics and Epidemiology of Chronic Critically Ill Patients in China

This study aims to enroll chronic critically ill patients in ICU to investigate the epidemiology of chronic critically ill in China and identify risk factors of poor outcomes among those patients. The main question it aims to answer is:

What is the one year mortality of chronic critically ill patients in China? We conduct semi-structured telephone follow-ups to investigate the long-term outcomes of chronic critically ill patients.

Study Overview

• Status: Recruiting
• Conditions: Chronic Critically Ill

• Study Type: Observational
• Enrollment (Estimated): 459

Contacts and Locations

Study Locations

• China
  • Sichuan
    • Chengdu, Sichuan, China, 610041
      • Recruiting
      • West China Hospital of Sichuan University
      • Contact: Xuepeng Zhang, PhD; Phone Number: 8615882249643; Email: zhang_xuepeng@wchscu.cn

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: No

• Sampling Method: Probability Sample

Study Population

This is a prospective cohort study that will consecutively enroll patients meeting the criteria for Chronic Critical Illness (CCI) from the Intensive Care Units of several hospitals in China over a one-year period starting March 2025.

Description

Inclusion Criteria:

- Must meet: Age greater than 18 years old; Stay in ICU for 8 days or more.

Meet any of the following criteria:

Tracheotomy; Continuous mechanical ventilation for over 96 hours; Multiple organ failure; Sepsis or severe infection; Severe trauma; Severe brain injury;

Exclusion Criteria:

- Refusing to accept follow-up; Patients who have been lost to follow-up;

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
one year mortality	one year mortality	one year

Collaborators and Investigators

• Sponsor: West China Hospital

Study record dates

Study Major Dates

• Study Start (Actual): March 29, 2025
• Primary Completion (Estimated): February 1, 2029
• Study Completion (Estimated): June 1, 2029

Study Registration Dates

• First Submitted: January 19, 2026
• First Submitted That Met QC Criteria: January 19, 2026
• First Posted (Actual): January 28, 2026

Study Record Updates

• Last Update Posted (Actual): January 28, 2026
• Last Update Submitted That Met QC Criteria: January 19, 2026
• Last Verified: January 1, 2026

More Information

Terms related to this study

• Other Study ID Numbers: 2026-01-12

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No