Lateral Rectus Muscle Strangulation in Cases of Exotropia

January 22, 2026 updated by: Amr Mounir, Sohag University

Lateral Rectus Muscle Strangulation: A New Weakening Technique in Cases of Exotropia

The goal of our study to evaluate effect of lateral rectus muscle strangulation as a novel effective weakening technique in cases of exotropia.

It is a case-series intervensional study with a total 12 participant who are diagnosed as exophoria or intermittent exotropia who are older than 4 years old.

All patients will be assessed regarding their angle of deviation and then undergo lateral rectus muscle strangulation under general anesthesia and then will be followed- up at 1st day, 1st week, 1st month and 6th months.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

Under general anesthesia and after sterilization and draping of the eyes, an eye speculum is inserted. The muscle is exposed and hooked through either a fornix-based or limbal-based incision. Careful dissection is carried out to delineate the muscle edge, a previously measured blook of the lateral rectus muscle is sutured (strangulated) with proline 10/0 as in (fig-1). Patients will be followed-up next day after surgery then after 1 month and after 6 months.

Study Type

Interventional

Enrollment (Actual)

12

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Egypt
      • Sohag, Egypt
        • Sohag University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • intermittent exotropia

Exclusion Criteria:

  • previous squint surgery

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: N/A
  • Interventional Model: Single Group Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: lateral rectus muscle strangulation
lateral rectus muscle strangulation as a weakening technique in cases of exotropia.
Procedure: Muscle strangulation
lateral rectus muscle strangulation as a weakening technique in cases of exotropia.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Correction of strabismus
Time Frame: 12 months
the correction was done by lateral rectus muscle strangulation
12 months

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
orthophoria
Time Frame: 12 months
to make both eyes aligned together, and to maintain orthophoria
12 months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Sohag University

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Helpful Links

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

January 1, 2024

Primary Completion (Actual)

July 1, 2024

Study Completion (Actual)

February 2, 2025

Study Registration Dates

First Submitted

September 25, 2025

First Submitted That Met QC Criteria

January 22, 2026

First Posted (Actual)

January 28, 2026

Study Record Updates

Last Update Posted (Actual)

January 28, 2026

Last Update Submitted That Met QC Criteria

January 22, 2026

Last Verified

September 1, 2025

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • Soh-Med-24-09-12PD

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

UNDECIDED

IPD Plan Description

we havenot decided until now to share IPD with other researchers

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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