Comparative Effects of Strain Counter Strain and Myofascial Release in Patients With Knee Osteoarthritris

February 23, 2026 updated by: Riphah International University

Comparative Effects of Strain Counter Strain and Myofascial Release on Pain, Function and Quality of Life in Patients With Knee Osteoarthritis

Osteoarthritis is a degenerative disease, the cartilage present in the joint gets damaged and the bones become hypertrophied. In US, the most commonly occuring arthritis is osteoarthritis. Myofascial release focuses on fascia. Strain counter strain is positional release

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

44

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Pakistan
    • Punjab Province
      • Lahore, Punjab Province, Pakistan, 54000
        • Psrd Hospital

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • Both males and females were included in the study.
  • Patients aged 40 to 65 with clinical diagnosis of osteoarthritis
  • Patient with Grade 2 osteoarthritis
  • Patient with Grade 2 osteoarthritis
  • Patients who have not undergone any surgical intervention on the Knee in the past 6 months.
  • Overweight and obese people with (BMI of 25-29.9), BMI of 30 or above

Exclusion Criteria:

  • Patients with history of knee surgery or joint replacement
  • Patients with neurological conditions that could affect mobility or perception of pain.
  • Patients with infections in the knee area
  • Patients with any traumatic injury
  • Pregnant Patients

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Double

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: experimental: Strain Counter Strain
Strain Counter Strain involves positioning of hypertonic muscles and dysfunctional joints towards position of comfort. Initial session 2 to 3 times per week. Hot packs 2 to 3 times per week. Tens 2 to 3 times per week. Each session lasts 30 to 60 minutes holding the position for 90 seconds to 2 minutes. Exercises includes.
Other: Strain Counter Strain
Strain Counter Strain involves passive positioning of hypertonic muscles and dysfunctional joints towards position of comfort. Conventional treatment includes Hot pack, Tens 2 to 3 times per week. Isometric exercises of Quadriceps, Hamstrings, Adductors and Calf muscles
Active Comparator: Active Comparator: Myofascial Release
Myofascial release focuses on the fascia , connective tissue that surrounds muscles, bones and organs which becomes tight and restrict movement. ,Myo fascial release 2 to 3 times per week. 60 seconds per area. Hot packs 2 to 3 times per week. Low frequency TENS. Foam rolling for Calves and Hamstrings. Quadriceps isometric Contraction holds for 10 to 15 seconds with 2 to 4 sets of each exercise. Hamstrings and Adductor isometric contractions.
Other: Myofascial Release
Perform myofascial release technique 2 to 3 times per week. Time 60 seconds per area. Frequency 3 times a week. Hot packs applied 2 to 3 times per week Tens 2 to 3 times per week. Isometric contractions of Quadriceps, Hamstrings , Adductors and Calf muscles hold 10 to 15 seconds then gradually increase 30 seconds with 2 to 4 sets of each exercise

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Numeric Pain Rating Scale
Time Frame: at the baseline and at the end of 4 week
The Numeric Pain Rating Scale is a very common tool to asses pain in clinical settings. It is 0 to 10 pain rating scale in which 0 indicates no pain and 10 indicates worse pain.
at the baseline and at the end of 4 week
Quality of Life (QoL)
Time Frame: at the baseline of 4 weeks
QoL is 26 item tool for reliability, validity and responsiveness to changes in health.
at the baseline of 4 weeks

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Time Up and Go Test TUG
Time Frame: at the baseline and at the end of 4 weeks
In the Time Up and Go Test (TUG), Subjects are asked to rise from a standard armchair, walk from a marker 3m away, turn, walk back and sit down again. This test is reliable and valid test for quantifying functional mobility that may also be useful in following clinical change over time.
at the baseline and at the end of 4 weeks

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Riphah International University

Investigators

  • Principal Investigator: Naila kanwal, TPT, Riphah International University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

January 13, 2025

Primary Completion (Actual)

November 17, 2025

Study Completion (Actual)

November 17, 2025

Study Registration Dates

First Submitted

February 4, 2026

First Submitted That Met QC Criteria

February 4, 2026

First Posted (Actual)

February 11, 2026

Study Record Updates

Last Update Posted (Actual)

February 25, 2026

Last Update Submitted That Met QC Criteria

February 23, 2026

Last Verified

February 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • REC/RCR & AHS/24/0194

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Clinical Trials on Knee Osteoarthritis

Clinical Trials on Strain Counter Strain

Search Similar Trials

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Armenia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations

Subscribe