Impacted Tooth With Immediate Implant Placement (ImmediateIMP)

March 9, 2026 updated by: Giuseppe D'Albis, University of Bari Aldo Moro

Surgical Extraction of an Impacted Canine and Immediate Implant Placement: A Prosthetically Guided Digital Approach

This is a prospective study, in which there are involved four clinical cases of surgical extraction of impacted maxillary canines followed by immediate implant placement and immediate screw-retained temporary crown using a full-digital workflow that included performing a CBCT, an intraoral scan, AI-assisted segmentation, a virtual wax-up, and the design of a surgical guide and a 30° angled abutment. Then, the follow-up lasting two years is performed to verify the functional and esthetical outcomes. The patients included in this report are part of an ongoing clinical trial, and the complete data set will be published separately upon study completion. The aims is to present clinical outcomes and synthesize evidence comparing placing implant to avoid buccal augmentation using angles abutments versus performing guided bone regeneration (GBR) to allow ideal implant placement with straight abutments, and to evaluate the risk of abutment screw loosening.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

5

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Italy
      • Bari, Italy, 70124
        • Dr. Giuseppe D'Albis

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • Refuse Orthodontic treatments
  • Patients had to be healthy according to System of the American Society of Anesthesiology (ASA) and aged 18 years or older
  • No general medical condition representing a contraindication to implant therapy
  • minimum 2 missing teeth in the maxilla or mandible from the canine to the second molar
  • No periodontal disease (periodontal probing depth <4 mm) or treated periodontitis
  • Good oral hygiene (full mouth plaque index<25%)
  • Adequate control of inflammation (full mouth bleeding on probing<25%)

Exclusion Criteria:

  • smoking of more than 15 cigarettes a day
  • untreated periodontal disease
  • pregnancy or breastfeeding at date of inclusion
  • acute infections
  • keratinized mucosal tissue less than 2 mm

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: N/A
  • Interventional Model: Single Group Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Patients with impacted tooth
Patient with impacted Maxillary Canine.
Procedure: Implantology
Following local anesthetic infiltration and a minimally invasive access, the atraumatic extraction of the impacted canine is performed, preserving the vestibular soft and bone tissues. The implant site is then prepared, and the implant is placed using the surgical guide, with the required insertion torque to achieve primary implant stability.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Periimplant chart
Time Frame: 3 month after implant insertion, 1 year, 2 years
Probing the implant in 6 site.
3 month after implant insertion, 1 year, 2 years
ISQ
Time Frame: At implant insertion and after 3 months
Implant stability quotient. ( 0 - 100)
At implant insertion and after 3 months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

University of Bari Aldo Moro

Investigators

  • Principal Investigator: Giuseppe D'Albis, Dr., University of Bari Aldo Moro
  • Study Director: Saverio Capodiferro, Prof. Dr., University of Bari Aldo Moro
  • Principal Investigator: Francesco Colacicco, University of Bari Aldo Moro
  • Study Director: Massimo Corsalini, Prof. Dr., University of Bari Aldo Moro

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

January 1, 2024

Primary Completion (Actual)

March 1, 2026

Study Completion (Actual)

March 1, 2026

Study Registration Dates

First Submitted

March 2, 2026

First Submitted That Met QC Criteria

March 2, 2026

First Posted (Actual)

March 6, 2026

Study Record Updates

Last Update Posted (Actual)

March 11, 2026

Last Update Submitted That Met QC Criteria

March 9, 2026

Last Verified

March 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • TiltedImplant2026

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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