Three Dimensional Movement Analysis of Maxillary Impacted Canine: a Randomized Clincial Trial

Three Dimensional Movement Analysis of Maxillary Impacted Canine Using TADs: a Randomized Clinical Trial

Maxillary canines are the second-most frequently impacted teeth in the dental arch after the third molars. The suspicion of a maxilary canine impaction raises with the absence of the permanent canine in the arch after the normal period of eruption, and has to be confirmed by a clinical evaluation of the patient and a radiographic assessment.

The approaches to the management of impacted canines are many, but the preferred approach typically involves surgical exposure and guided orthodontic eruption.

The initial mechanical eruption can be achieved in several ways, but an important distinction has to be done according to the anchorage method. The aim of this study is comparing Temporary Anchorage Devices (TADs), and cantilevers with a TMA sectional, using the quantification of canines and molars displacement as the main parameter.

A TAD is a mini screw temporarily fixed to bone for the purpose of enhancing orthodontic anchorage either by supporting the reactive unit (the anchoring tooth) or by obviating the need for it at large, and is subsequently removed after use.

The mini screw employed in this clinical trial will be an alloy type IV titanium screw with 1.5mm diameter and 8-10 mm long, and under local anesthesia will be placed in an area between the first premolar and first molar, on the buccal or labial side according to the canine position and teeth position.

For the evaluation of the canines and molar displacement, two CBCT will be required: the first one before the beginning of the traction (T0), the second one after three months (T1). Both the CBCT will be imported in the MIMICS image processing software (Materialize Group, Leuven, Belgium). Limiting the tissue density ranges and restricting the anatomical area of interest, a cropped colored mask will be obtained from each CBCT. Then the co-registration, through the identification of 5 at least landmark points, will allow the overlap of the two masks. At this point, calculating the 3D surface models, the tooth pre- and post-treatment positions will be evident and the measurement of the displacement possible.

Study Overview

• Status: Completed
• Conditions: Complicated Impacted Tooth
• Intervention / Treatment: Device: TPA; Device: miniscrew

• Study Type: Observational
• Enrollment (Actual): 16

Contacts and Locations

Study Locations

• Italy
  • Genoa, Italy, 16100
    • Orthodontics Department, Dental School, Genoa University. Italy

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 10 years to 60 years (Child, Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

Patients referred to the Orthodontic Department, Genoa University.

Description

Inclusion Criteria:

• presence of one or two impacted maxillary canine requiring surgical exposure and orthodontic treatment

Exclusion Criteria:

• permanent teeth extraction-based treatment
• current or previous orthodontic treatment in the last 12 months
• current systemic disease
• current antibiotic or antinflammatory therapy that can may compromise the result

Study Plan

How is the study designed?

Design Details

• Observational Models: Cohort
• Time Perspectives: Prospective

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
group 1; Patient treated with Trans Palatal Arch as anchorage for canine traction	Device: TPA
Group 2; Patient treated with miniscrew as anchorage for canine traction	Device: miniscrew

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Canine movement	Superimposition of two consecutive TC cone beam using at least 5 landmarks point. Calculation of the 3D surface model and the measureament of the canine and first molar movement	baseline and 3 months after starting treatment

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Side effect of traction	Evaluation of Root cervical resorption of other teeth due to canine movement Bone density after three month of traction	baseline and end of treatment

Collaborators and Investigators

• Sponsor: University of Genova
• Collaborators: University of Michigan
• Investigators: Study Director: Armando Silvestrini Biavati, MD, DDS, Genoa University, Italy; Principal Investigator: Marco Migliorati, DDS, MSc, Genoa University, Italy

Publications and helpful links

General Publications

• Migliorati M, Cevidanes L, Sinfonico G, Drago S, Dalessandri D, Isola G, Biavati AS. Three dimensional movement analysis of maxillary impacted canine using TADs: a pilot study. Head Face Med. 2021 Jan 15;17(1):1. doi: 10.1186/s13005-020-00252-0.

Study record dates

Study Major Dates

• Study Start: September 1, 2011
• Primary Completion (Actual): April 1, 2019
• Study Completion (Actual): April 14, 2019

Study Registration Dates

• First Submitted: October 26, 2012
• First Submitted That Met QC Criteria: October 26, 2012
• First Posted (Estimate): October 30, 2012

Study Record Updates

• Last Update Posted (Actual): April 16, 2019
• Last Update Submitted That Met QC Criteria: April 14, 2019
• Last Verified: April 1, 2019

More Information

Terms related to this study

• Keywords: impacted canine; miniscrew; cone beam
• Additional Relevant MeSH Terms: Stomatognathic Diseases; Tooth Diseases; Tooth, Impacted
• Other Study ID Numbers: MVM1; GU-1 (Other Identifier: Genoa University)