Clinical Trials on Age-related Wet Macular Degeneration in Singapore

Total 59 results

Singapore National Eye Centre
Bayer

Completed

An Open Label-study to Compare the Efficacy of Aflibercept Monotherapy for Polypoidal Choroidal Vasculopathy

Age Related Macular Degeneration | Polypoidal Choroidal Vasculopathy

Singapore
Hoffmann-La Roche

Recruiting

A Study of the Efficacy, Safety, and Pharmacokinetics of A 36-Week Refill Regimen for the Port Delivery System With Ranibizumab in Patients With Neovascular Age-Related Macular Degeneration (Velodrome)

Neovascular Age-related Macular Degeneration (nAMD)

Belgium, Korea, Republic of, Germany, Spain, United Kingdom, Australia, Italy, Argentina, Israel, Austria, Brazil, France, Singapore, Switzerland, Taiwan, Turkey
Hoffmann-La Roche

Active, not recruiting

A Study to Evaluate the Long-Term Safety and Tolerability of Faricimab in Participants With Neovascular Age-Related Macular Degeneration (AVONELLE-X)

Neovascular Age-related Macular Degeneration

United States, Korea, Republic of, United Kingdom, Japan, Canada, Turkey, Argentina, Australia, Denmark, France, Germany, Hungary, Italy, Poland, Spain, Singapore, Austria, Brazil, Hong Kong, Israel, Portugal, Russian Federation, Ta... and more
Chengdu Kanghong Biotech Co., Ltd.

Terminated

Efficacy and Safety Trial of Conbercept Intravitreal Injection for Neovascular AMD (PANDA-1)

Neovascular Age-related Macular Degeneration

United States, Argentina, Australia, Austria, Belgium, Canada, Chile, Colombia, Germany, Hong Kong, Lithuania, Mexico, Netherlands, New Zealand, Peru, Philippines, Poland, Portugal, Singapore, Spain, Switzerland, Taiwan
Bayer
Regeneron Pharmaceuticals

Active, not recruiting

Study of the Effects of High Dose Aflibercept Injected Into the Eye of Patients With an Age-related Disorder That Causes Loss of Vision Due to Growth of Abnormal Blood Vessels at the Back of the Eye (PULSAR)

Neovascular Age-Related Macular Degeneration

United States, Spain, Korea, Republic of, Czechia, Japan, Singapore, China, Serbia, Lithuania, Taiwan, Australia, Estonia, Austria, Israel, France, Italy, Switzerland, Slovakia, Ukraine, Bulgaria, Portugal, Latvia, Canada, Hungary, Arge... and more
National University of Singapore
National University Hospital, Singapore; Ministry of Education, Singapore

Active, not recruiting

Impact of Regular Consumption of Grapes on Eye Health in Singapore Older Adults

Age-related Macular Degeneration | Eye Health

Singapore
Novartis Pharmaceuticals

Completed

Observe the Effectiveness and Safety of Ranibizumab in Real Life Setting (LUMINOUS)

Diabetic Macular Edema | Retinal Vein Occlusion | Wet Age Related Macular Degeneration | Wet Age Related Macular Degeneration, Diabetic Macular Edema, Retinal Vein Occlusion

Spain, China, Colombia, Korea, Republic of, Belgium, Greece, Japan, Russian Federation, Turkey, United Kingdom, Egypt, Germany, Australia, Canada, France, Austria, Hong Kong, Hungary, Israel, Netherlands, Peru, Singapore, Slovakia, Sl... and more
Novartis Pharmaceuticals

Completed

UNcovering the Difference Between Ranibizumab and Aflibercept, Focusing on Systemic Anti-vascular Endothelial Growth Factor (VEGF) Effects in Patients With neovascuLar Age-related Macular Degeneration (AMD) (UNRAVEL)

Neovacular Age-related Macular Degeneration

Taiwan, Thailand, Israel, Korea, Republic of, Philippines, Singapore, Malaysia
Shanghai Henlius Biotech

Active, not recruiting

A Phase 3 Study to Compare the Efficacy and Safety of HLX04-O With Ranibizumab in Subjects With wAMD

Age Related Macular Degeneration

United States, Singapore, Spain, Germany, Slovakia, China, Hungary, Australia, Bulgaria, Poland, Latvia, Czechia, France, Italy, Serbia
Hoffmann-La Roche

Recruiting

A Real-World Study to Gain Clinical Insights Into Roche Ophthalmology Products (VOYAGER)

Diabetic Macular Edema | Neovascular Age-related Macular Degeneration

Germany, Japan, United Kingdom, Spain, United States, Italy, Switzerland, Canada, France, Australia, Singapore, Puerto Rico, United Arab Emirates, Bulgaria, Croatia, Chile
Novartis Pharmaceuticals

Completed

Visual Outcome in Patients With Symptomatic Macular Polypoidal Choroidal Vasculopathy (PCV) Treated With Either Ranibizumab as Monotherapy or Combined With Verteporfin Photodynamic Therapy (vPDT) (EVEREST II)

Age-related Macular Degeneration | Polypoidal Choroidal Vasculopathy

Japan, Taiwan, Hong Kong, Singapore, Thailand, Korea, Republic of, Malaysia
Singapore Eye Research Institute
University of Melbourne; Curtin University; Singapore National Eye Centre; Ministry...

Unknown

Living Successfully With Chronic Eye Diseases (ADAPT-LAH)

Glaucoma | Diabetic Retinopathy | Age-related Macular Degeneration | Low Vision | Chronic Diseases

Singapore
Hoffmann-La Roche

Completed

A Study to Evaluate the Efficacy and Safety of Faricimab in Participants With Neovascular Age-Related Macular Degeneration (LUCERNE)

Wet Macular Degeneration

Korea, Republic of, United States, China, Argentina, Australia, Denmark, France, Germany, Italy, Poland, Spain, Singapore, Austria, Brazil, Hong Kong, Hungary, Portugal, Russian Federation, Taiwan, Turkey, Bulgaria
National University of Singapore

Recruiting

Impact of Comprehensive Dietary Counseling on Dietary Quality, Mental Health, and Quality of Life in Older Adults

Aging | Age Problem | Age-related Cognitive Decline | Age-Related Atrophy

Singapore
National University of Singapore

Active, not recruiting

Youth Outlook on Life Opportunities Study

Anxiety | Educational Problems | Marriage Age | Childbearing, Delayed | Age Related Female Infertility

Singapore
Singapore National Eye Centre
Santen Pharmaceutical Co., Ltd.; Singapore Eye Research Institute

Unknown

Diabetic Macular Edema Asian Response (DEAR) Study: Biomarkers for Response to Aflibercept in Asian Patients With Center Involving DME

Diabetic Macular Edema

Singapore
Singapore National Eye Centre

Completed

Optical Coherence Tomography Imaging of the Posterior Segment in High Myopia.

Glaucoma | Myopia | Maculopathy

Singapore
Duke-NUS Graduate Medical School
Singapore General Hospital; Agency for Science, Technology and Research; Singapore... and other collaborators

Completed

Effectiveness of a Brain-Computer Interface Based System for Cognitive Enhancement in the Normal Elderly (3ECog)

Dementia | Mild Cognitive Impairment | Alzheimer's Disease | Age-Related Cognitive Decline

Singapore
Allergan

Completed

A Study of the Safety and Efficacy of a New Treatment for Diabetic Macular Edema

Diabetic Macular Edema

United Kingdom, Taiwan, Colombia, Korea, Republic of, Singapore, Brazil, New Zealand, Poland, Hungary, Italy, India, France, United States, Canada
Institute of Mental Health, Singapore
Singapore Clinical Research Institute

Completed

Lofexidine for Inpatient Opiate Detox in Singapore

Opiate Dependent Patients Who Are Undergoing Inpatient Detoxification in Singapore

Singapore
Duke-NUS Graduate Medical School
Singapore General Hospital; Tan Tock Seng Hospital; National University, Singapore and other collaborators

Completed

Brain-Computer Interface System for Training Memory and Attention in Elderly

Dementia | Mild Cognitive Impairment | Alzheimer's Disease | Age-Related Cognitive Decline

Singapore
Allergan

Completed

A Study of the Safety and Efficacy of a New Treatment for Macular Edema Resulting From Retinal Vein Occlusion

Macular Edema | Retinal Vein Occlusion

United States, Poland, United Kingdom, Colombia, Spain, Korea, Republic of, Singapore, Brazil, New Zealand, Hong Kong, Italy, Canada, India
Bayer
Regeneron Pharmaceuticals

Completed

Aflibercept in Polypoidal Choroidal Vasculopathy (PLANET)

Neovascular Macular Degeneration

Taiwan, Hong Kong, Korea, Republic of, Japan, Singapore, Australia, Hungary, Germany
Hoffmann-La Roche

Recruiting

Vamikibart in Participants With Uveitic Macular Edema (Sandcat)

Uveitic Macular Edema

India, United States, Japan, Australia, Singapore, Turkey, Argentina, Czechia, Spain, France, Germany, Switzerland
Novartis

Completed

Efficacy and Safety of Ranibizumab (Intravitreal Injections) in Patients With Visual Impairment Due to Diabetic Macular Edema (REVEAL)

Diabetic Macular Edema

Hong Kong, Taiwan, Singapore, Korea, Republic of, China, Japan
National Heart Centre Singapore
National University Hospital, Singapore

Unknown

SAPhIRE Statin Adverse Drug Reaction (STATIN)

Myopathy

Singapore
Novartis Pharmaceuticals

Completed

To Assess the Efficacy and Safety of Intravitreal Ranibizumab in People With Vision Loss Due to Macular Edema

Macular Edema (ME)

Russian Federation, Turkey, United Kingdom, Belgium, Australia, Hungary, Switzerland, Germany, Italy, Korea, Republic of, Israel, Spain, France, Latvia, Netherlands, Slovakia, Czech Republic, Singapore, Canada
Allergan

Completed

A Safety and Efficacy Study of Abicipar Pegol in Participants With Neovascular Age-related Macular Degeneration (CEDAR)

Macular Degeneration

Spain, United States, Korea, Republic of, Israel, Singapore, Argentina, Germany, France, Czechia, Austria, Philippines, Switzerland, Chile, Colombia, Hong Kong, Latvia, New Zealand
Hoffmann-La Roche

Completed

A Study to Evaluate the Long-Term Safety and Tolerability of Faricimab in Participants With Diabetic Macular Edema (Rhone-X)

Diabetic Macular Edema

United States, Korea, Republic of, United Kingdom, Brazil, Japan, Canada, Argentina, Australia, Austria, Denmark, France, Germany, Hungary, Italy, Poland, Slovakia, Spain, Singapore, Czechia, Hong Kong, Israel, Portugal, Russian Federation and more
Hoffmann-La Roche

Completed

A Study to Evaluate the Efficacy and Safety of Faricimab (RO6867461) in Participants With Diabetic Macular Edema (RHINE)

Diabetic Macular Edema

Korea, Republic of, United States, United Kingdom, Brazil, China, Canada, Argentina, Australia, Denmark, France, Italy, Poland, Spain, Germany, Singapore, Czechia, Hong Kong, Portugal, Russian Federation, Taiwan, Hungary, Switzerland and more
National Heart Centre Singapore
National University Hospital, Singapore; Khoo Teck Puat Hospital; Singapore General...

Not yet recruiting

REducing Diabetic macrovascUlar Complications duE to Peripheral Arterial Disease- REDUCE-PAD (REDUCE-PAD)

Diabetes Mellitus, Type 2 | Peripheral Arterial Disease

Singapore
Hoffmann-La Roche
Chugai Pharmaceutical

Completed

A Study to Evaluate the Efficacy and Safety of Faricimab in Participants With Macular Edema Secondary to Branch Retinal Vein Occlusion (BALATON)

Macular Edema | Branch Retinal Vein Occlusion

United States, Korea, Republic of, Brazil, Japan, United Kingdom, China, Argentina, Australia, France, Germany, Hungary, Italy, Poland, Spain, Singapore, Austria, Czechia, Hong Kong, Israel, Portugal, Russian Federation, Taiwan
Novartis Pharmaceuticals

Completed

A Study of the Efficacy and Safety of Brolucizumab vs. Aflibercept in Patients With Visual Impairment Due to Diabetic Macular Edema (KITE)

Diabetic Macular Edema

Czechia, India, Russian Federation, Taiwan, Turkey, Lebanon, Denmark, Estonia, France, Germany, Hungary, Korea, Republic of, Latvia, Lithuania, Bulgaria, Norway, Belgium, Malaysia, Sweden, Slovakia, Singapore, Poland, Switzerland
National Heart Centre Singapore
National Medical Research Council (NMRC), Singapore

Recruiting

Evaluating DyNamic Myocardial Blood Flow QUantitation As a Cost Effective Care ModeL for DiabEtic Patients With Coronary Artery DiSease (NUCLEuS)

Coronary Artery Disease | Diabetes Mellitus

Singapore
Bayer
Regeneron Pharmaceuticals

Completed

Vascular Endothelial Growth Factor (VEGF) Trap-Eye: Investigation of Efficacy and Safety in Wet Age-Related Macular Degeneration (AMD) (VIEW 2)

Macular Degeneration

Belgium, Israel, Italy, Spain, Korea, Republic of, Switzerland, Germany, Portugal, Japan, France, Australia, Netherlands, India, Austria, Brazil, Poland, United Kingdom, Singapore, Hungary, Latvia, Mexico, Czech Republic, Colombia, Ar... and more
Singapore National Eye Centre
National Medical Research Council (NMRC), Singapore; Singapore Eye Research... and other collaborators

Completed

Autologous ex Vivo Conjunctival Epithelial Cell Expansion for Ocular Surface Transplantation

Pterygium | Ocular Surface Disease | Chemical Injury | Stevens Johnson Syndrome

Singapore
National Heart Centre Singapore
Singapore National Eye Centre

Unknown

REWARD: Using the REtina as a Window To Detect Cardiac microvasculAR Dysfunction In Diabetes Mellitus

Microalbuminuria | Diastolic Dysfunction | Retinopathy, Diabetic

Singapore
Hoffmann-La Roche
Chugai Pharmaceutical

Completed

A Study to Evaluate the Efficacy and Safety of Faricimab in Participants With Macular Edema Secondary to Central Retinal or Hemiretinal Vein Occlusion (COMINO)

Central Retinal Vein Occlusion | Macular Edema | Hemiretinal Vein Occlusion

United States, Korea, Republic of, Brazil, Japan, United Kingdom, China, Argentina, Australia, France, Hungary, Italy, Poland, Spain, Singapore, Austria, Czechia, Germany, Hong Kong, Israel, Portugal, Russian Federation, Taiwan
Changi General Hospital
Khoo Teck Puat Hospital; Singapore General Hospital; Tan Tock Seng Hospital; National... and other collaborators

Completed

Primary Aldosteronism and Surgically Curable Forms in Hypertension Patients Using 11C-Metomidate

Primary Aldosteronism | Primary Aldosteronism Due to Aldosterone Producing Adenoma

Singapore
Changi General Hospital

Completed

Prevalence of Primary Aldosteronism in Patients With Stroke

Stroke | Primary Aldosteronism

Singapore
Changi General Hospital
Khoo Teck Puat Hospital; Singapore General Hospital; Tan Tock Seng Hospital; Sengkang... and other collaborators

Recruiting

11C-Metomidate PET/CT for Endocrine Hypertension and Characterisation of Adrenal Tumours

Primary Aldosteronism | Primary Aldosteronism Due to Aldosterone Producing Adenoma | Adrenal Tumors

Singapore
National Heart Centre Singapore

Recruiting

Molecular and Imaging Studies of Cardiovascular Health and Disease (Biobank)

Healthy | Ischemic Heart Disease | Dilated Cardiomyopathy | Hypertrophic Cardiomyopathy

Singapore
Singapore Chung Hwa Medical Institution
Ministry of Health, Singapore

Recruiting

Investigating the Syndrome Differentiation of Diabetic and Pre-diabetic Using Digitalized TCM Diagnostic Tools

Hypertension | Healthy | Diabete Mellitus | Pre-diabetes | Dyslipidemia Associated With Type II Diabetes Mellitus

Singapore
Changi General Hospital
ELO Water Pte. Ltd.

Completed

Assessing the Effects of ELO Water on Diabetic Foot Ulcers

Foot Ulcer, Diabetic

Singapore
Singapore General Hospital

Completed

An Observational Clinical Trial Examining the Effect of Topical Oxygen Therapy (NATROX™) on the Rates of Healing of Chronic Diabetic Foot Ulcers

Diabetic Foot Ulcer | Non-healing Wound

Singapore
National University of Singapore
National Heart Centre Singapore

Completed

Rapid Eye Movement Related OSA in Diabetic Versus Non-Diabetic Patients Treated With PCI

Coronary Artery Disease | Diabetes Mellitus | Obstructive Sleep Apnea

Singapore
Nanyang Technological University
Tan Tock Seng Hospital; Ministry of Health, Singapore

Completed

Diabetes Footcare Companion App for Patients and Carers

Diabetes Mellitus, Type 2 | Diabetic Foot | Diabetic Foot Infection | Ulcer Foot | Diabetes Mellitus Foot Ulcer | Ulcer, Leg

Singapore
National Heart Centre Singapore

Unknown

MRI Sequence and Imaging Protocol Development (BikeMRI)

Hypertension | Ischemic Heart Disease | Cardiomyopathy, Dilated | Cardiomyopathy, Hypertrophic | Left Ventricular Hypertrophy

Singapore
National University Hospital, Singapore
Celgene; International Myeloma Foundation; The Australasian Leukaemia & Lymphoma...

Unknown

Carfilzomib Thalidomide and Dexamethasone in Patients With Relapsed and/or Refractory Multiple Myeloma

Relapsed and/or Refractory Multiple Myeloma

Singapore, Hong Kong, Korea, Republic of, Taiwan
Novartis Pharmaceuticals

Completed

A Phase I-Ib/II Study to Determine the Maximum Tolerated Dose (MTD) of AUY922 Alone and in Combination With Bortezomib, With or Without Dexamethasone, in Patients With Relapsed or Refractory Multiple Myeloma.

Relapsed or Refractory Multiple Myeloma

Germany, Spain, Singapore, United States, Australia

Clinical Trials on Age-related Wet Macular Degeneration in Singapore

Sponsors and Collaborators

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CROs in Bosnia & Herzegovina

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