Clinical Trials on Bone Fractures in Czechia

Total 378 results

University Hospital Ostrava

Completed

Comparison of Conservative and Operative Treatment of Jones Fracture

Fracture of Fifth Metatarsal Bone

Czechia
GlaxoSmithKline

Terminated

A Phase IIa Study Of Men And Post-Menopausal Women With A Fractured Distal Radius

Fracture Healing

Russian Federation, Argentina, Hong Kong, Netherlands, Spain, Taiwan, Korea, Republic of, Australia, United Kingdom, Czech Republic, South Africa, Romania, Sweden
University Hospital Ostrava

Recruiting

Postoperative Pain Relieve for Patients Undergoing Surgical Treatment of Femoral Fracture

Proximal Femur Fracture

Czechia
Brno University Hospital
St. Anne's University Hospital Brno, Czech Republic

Completed

Mortality Following Surgery for Proximal Femoral Fractures (HipMo)

Fracture of Neck of Femur (Hip)

Czech Republic
Bone Therapeutics S.A
ICON plc

Recruiting

Study to Assess the Efficacy and Safety of Allogeneic Osteoblastic Cells (ALLOB®) Single Implantation in Tibial Fracture (ALLOB-TF2)

Tibial Fracture

Belgium, Czechia, France, Germany, Hungary, Poland, Spain
Bayside Health
National Health and Medical Research Council, Australia; Monash University

Completed

Hyperbaric Oxygen in Lower Leg Trauma

Tibial Fracture | Soft Tissue Injury

Australia, Sweden, Chile, United States, Austria, India, Italy, Portugal, Czechia
Charles University, Czech Republic
Faculty Hospital Kralovske Vinohrady

Completed

Celecoxib in Postoperative Analgesia for Radius Fracture Surgery

Pain, Postoperative

Czechia
Eli Lilly and Company

Completed

A Study That Will Compare the Effect of Two Drugs on Participants With Low Bone Mass and a Recent Hip Fracture (MOVE)

Osteoporosis

United States, Spain, France, Mexico, Italy, Greece, Croatia, Denmark, Germany, Czechia, Canada, Norway
AO Clinical Investigation and Publishing Documentation

Terminated

Spine FA3 - a Prospective, International, Multicenter Cohort Study on Treatment of of AO A3 Thoracolumbar Fractures (FA3)

Single Level Stable Thoracolumbar Fracture Type AO A3 | Multiple Level Stable Thoracolumbar Fracture Type AO A3

Brazil, Germany, Chile, Czechia, Italy, Portugal
Kuros Biosurgery AG
Baxter BioScience

Completed

Adjunctive Therapy to Treat Tibial Shaft Fractures (TSF)

Trauma

Bulgaria, Czech Republic, Finland, France, Germany, Hungary, Italy, Romania, Serbia, Slovakia, Slovenia, Switzerland
Petr Routner

Recruiting

Diagnostic Ultrasonography in Physiotherapy (SonograPHY)

Ankle Injuries | Ankle Fractures | Ankle Sprains | Ankle Edema | Ankle Impingement

Czechia
Charles University, Czech Republic

Completed

Vaginal Birth After Caesarean Section and Levator Ani Avulsion

Birth Injuries

Czechia
Eli Lilly and Company

Completed

VERtebral Fracture Treatment Comparisons in Osteoporotic Women (VERO)

Postmenopausal Osteoporosis

United States, Germany, Hungary, Italy, Spain, Belgium, France, Poland, Austria, Canada, Puerto Rico, Argentina, Greece, Brazil, Czechia
vTv Therapeutics

Completed

Factor IX Inhibition in Thrombosis Prevention (The FIXIT Trial)

Embolism and Thrombosis | Hip Fractures | Venous Thromboembolism

Denmark, Czech Republic, Norway, Sweden
Jan Malecek

Completed

Can Ammonium Inhalants Maintain Performance in Sleep Deprived Soldiers?

Sleep | Cognitive Change | Sleep Deprivation | Military Activity | Military Combat Stress Reaction

Czechia
Sanofi

Completed

Evaluation of AVE5026 as Compared to Enoxaparin for the Prevention of Thromboembolism in Patients Undergoing Hip Fracture Surgery (SAVE-HIP2)

Venous Thromboembolism

United States, Canada, Poland, Romania, Russian Federation, Ukraine, Italy, Portugal, Spain, Sweden, Turkey, Bulgaria, India, Czech Republic, Mexico, Argentina, Denmark, Finland, Peru, Chile, Belarus, China, South Africa, Greece, Colombia
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of Bimagrumab in Patients After Hip Fracture Surgery

Muscle Wasting (Atrophy) After Hip Fracture Surgery

Colombia, Belgium, Hungary, Taiwan, Spain, Czechia, United States, France, Germany, Turkey, Japan, Russian Federation, United Kingdom, Argentina, Australia, Mexico, Chile, Switzerland, Austria
DePuy International

Terminated

A Single Centre Study to Assess the Long-term Performance of the Pinnacle™ Cup With a Ceramic-on-ceramic Bearing in Primary Total Hip Replacement

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Traumatic Femoral Fractures | Nonunion of Femoral Fractures

Czech Republic
Europainclinics z.ú.

Terminated

EuroPainClinics® Study I (Prospective Trial) (EPCSI)

Lumbar Spinal Stenosis

Czechia
Vericel Corporation

Completed

Superiority of MACI® Versus Microfracture Treatment in Patients With Symptomatic Articular Cartilage Defects in the Knee (SUMMIT)

Articular Cartilage Defect

Netherlands, Norway, France, Czechia, Sweden, Poland, United Kingdom
Enzene Biosciences Ltd.
Alkem Laboratories Ltd

Recruiting

A Phase 3 Study to Compare Biosimilar Denosumab With Prolia®

Postmenopausal Osteoporosis

Czechia
Tetec AG

Active, not recruiting

Phase III Study to Evaluate Safety and Effectiveness of NOVOCART 3D Plus vs. Microfracture in Knee Cartilage Defects (N3D)

Traumatic Articular Cartilage Defects in the Knee Joint

United Kingdom, Hungary, Czechia, Germany, Lithuania, Austria, France, Latvia, Poland, Switzerland
Europainclinics z.ú.

Completed

EuroPainClinics® Study II (Prospective Trial) (EPCSII)

Lumbar Spinal Stenosis

Czechia
Charles University, Czech Republic
University Hospital, Motol; Bulovka Hospital

Recruiting

T2MR PCR Detection of ESKAPE Pathogens in Patients With Pyogenic Spondylodiscitis and Infective Endocarditis

Endocarditis, Bacterial | Osteomyelitis; Vertebra

Czechia
Brno University Hospital

Recruiting

Anesthesiologic Management Effect on Perioperative Outcome in Scoliosis Surgery (SCOL)

Scoliosis

Czechia
DePuy International

Terminated

Multi-Centre Study to Assess the Long-term Performance of the DePuy ASR™ System in Resurfacing and Primary Total Hip Replacement

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Nonunion of Femoral Fractures

Austria, Czech Republic, Finland, Germany, Norway, Portugal, Switzerland, United Kingdom
Masaryk Memorial Cancer Institute

Recruiting

Optimization of Fractionation Schedules of Heel Spur Radiotherapy Prospective Randomized Open-label Trial

Heel Spur

Czechia
GlaxoSmithKline
Novartis Vaccines

Completed

Study to Evaluate Long Term Immunogenicity up to 10 Years After the First Booster Immunization With Tick Borne Encephalitis Vaccine in Adults Who Received 1 of 3 Different Primary Vaccination Schedules

Virus Diseases | Tick Borne Encephalitis

Czechia
Europainclinics z.ú.

Terminated

EuroPainClinics® Study III (Prospective Observational Study) (EPCSIII)

Disc Herniations

Czechia
Charles University, Czech Republic

Completed

Function of Inner Ear Such as Balance and Perception of Verticality in Children With Idiopathic Scoliosis

Idiopathic Scoliosis | Vestibular Abnormality

Czechia
Charles University, Czech Republic

Completed

Load During Sweep Rowing and the Influence on the Posture

Postural; Defect | Muscle Hypertonia | Postural Scoliosis

Czechia
Military University Hospital, Prague
University Hospital, Motol

Recruiting

The SPINUS II Study: Spinal Fusion for Multilevel SPECT/CT Positive Lumbar Degeneration

Degenerative Disc Disease | Back Pain Lower Back Chronic | Facet Joint Arthropathy | Facet Syndrome of Lumbar Spine

Czechia
Military University Hospital, Prague
University Hospital, Motol

Completed

The SPINUS I Study: Spinal Fusion for a Single Level SPECT/CT Positive Lumbar Degenerative Disc Disease

Degenerative Disc Disease | Back Pain, Low

Czechia
Masaryk University
Palacky University

Recruiting

Quantitative MR Parameters in Non-myelopathic Degenerative Cervical Spinal Cord Compression: a Longitudinal Study. (NOLOST)

Degenerative Cervical Spinal Myelopathy | Cervical Spinal Cord Compression

Czechia
Carebot s.r.o.

Completed

Retrospective Study of Carebot AI CXR Performance in Preclinical Practice

Pneumonia | Lung Diseases | Pneumothorax | Lung Cancer | Cardiomegaly | Artificial Intelligence | Pulmonary Edema | Pleural Effusion | Atelectasis | Consolidation | Hilar Calcification | Fracture Rib

Czechia
Aesculap AG
Raylytic GmbH

Recruiting

Post-Market Clinical Follow-Up Study on the Safety and Performance of Ennovate® Complex (COSINE)

Idiopathic Scoliosis | Hyperlordosis | Neuromuscular Scoliosis | Hyperkyphosis | Congenital Scoliosis

Czechia, Malaysia
Charles University, Czech Republic

Enrolling by invitation

The Comparison of Effectivity Therapy by HILT and TRT in Muscle Hypertonus

Muscle Tone Abnormalities | Muscle Spasm

Czechia
GlaxoSmithKline

Completed

The Aim of This Study is to Investigate the Persistence of Antibody Response in Adults up to 15 Years After One Booster Dose of GlaxoSmithKline (GSK) Biologicals' Encepur Adults Vaccine

Virus Diseases

Czechia
Brno University Hospital

Recruiting

Effect of Prophylactic Fibrinogen Concentrate In Scoliosis Surgery (EFISS)

Bleeding | Spine Deformity | Coagulopathy, Consumption | Fibrinogen

Czechia
Eli Lilly and Company

Completed

Bone Effects of Teriparatide Following Alendronate

Osteoporosis

Austria, Czech Republic
Novadip Biosciences

Completed

Safety and Preliminary Effectiveness of NVD-001 for the Treatment of Low Grade Degenerative Lumbar Spondylolisthesis (Spine1)

Spondylolisthesis

Czechia, Poland, Belgium
Amgen

Completed

A Randomized Phase 3 Study to Evaluate Two Formulations of Romosozumab in Postmenopausal Women With Osteoporosis

Postmenopausal Osteoporosis

United States, Poland, Czechia
Novartis Pharmaceuticals

Completed

Proof of Concept Study to Assess the Efficacy, Safety and Pharmacokinetics of LFG316 in Patients With Paroxysmal Nocturnal Hemoglobinuria

Paroxysmal Nocturnal Hemoglobinuria PNH

Lithuania, Japan, Czechia
St. Anna Kinderkrebsforschung

Completed

Allogeneic Stem Cell Transplantation for Children With CML

Chronic Myeloid Leukemia

Austria, Czechia, Italy
Isofol Medical AB

Completed

Investigation of [6R] 5,10-methylenetetrahydrofolate (Arfolitixorin) as Rescue Therapy for Osteosarcoma Patients Treated With HDMTX.

Osteosarcoma

Poland, Czechia, Hungary, Sweden
Faculty Hospital Kralovske Vinohrady

Completed

The Epidemiology, Management and Comorbidities in Alopecia Areata in Czech Republic

Infections | Multiple Sclerosis | Autoimmune Diseases | Diabetes Mellitus, Type 1 | Rheumatoid Arthritis | Vaccine Reaction | Inflammatory Bowel Diseases | Psoriasis | Crohn Disease | Ulcerative Colitis | Down Syndrome | Atopic Dermatitis | Vitiligo | Alopecia Areata | COVID-19 Pandemic | Ankylosing Spondylitis | Lupus Erythematosus and other conditions

Czechia
GlaxoSmithKline

Completed

Evaluation of Immune Memory to Twinrix or Comparator by Challenge Dose Administration 4 Years After Primary Vaccination

Hepatitis B | Hepatitis A

Belgium, Czechia
Sandoz
Hexal AG

Completed

Study Investigating PK, PD, Efficacy, Safety, and Immunogenicity of Biosimilar Denosumab (GP2411) in Patients With Postmenopausal Osteoporosis

Postmenopausal Women With Osteoporosis

United States, Bulgaria, Czechia, Japan, Poland, Spain
European Society for Blood and Marrow Transplantation
Novartis

Completed

Non Interventional Study on Iron Toxicity After First Allo-transplant in MDS/CMML

MDS | CMML

Germany, Belgium, Czechia
GlaxoSmithKline

Completed

Evaluation of Antibody Persistence & Immune Memory in Subjects Vaccinated During Adolescence With Twinrix™

Hepatitis B | Hepatitis A

Belgium, Czechia

Clinical Trials on Bone Fractures in Czechia

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