Clinical Trials on Mitral Insufficiency and Aortic Stenosis

Total 32689 results

Assistance Publique - Hôpitaux de Paris

Unknown

Aortic Stenosis in Elderly : Determinant of Progression

Aortic Stenosis | Elderly Gravida

France
Abbott Medical Devices

Recruiting

Post-Market Clinical Follow Up Study With Navitor Valve (VISTA)

Aortic Stenosis

Spain, Italy, France, Germany, Portugal, Switzerland
AUSL Romagna Rimini

Recruiting

Transfemoral Transcatheter Aortic Valve Implementation at Hospital Without On-site Cardiac Surgery: Early Clinical Outcome in Patients With Prohibitive Surgical Risk.

Aortic Stenosis

Italy
Medtronic Cardiac Surgery
Medtronic

Completed

PERIGON Japan Trial

Aortic Stenosis

Japan
Corcym S.r.l

Terminated

Sorin Universal REgistry on Aortic Valve Replacement (SURE-AVR)

Aortic Stenosis | Aortic Valve Disease

Belgium, France, Spain, Israel, United Kingdom, Australia, United States, Netherlands, Germany, Italy, Singapore, Switzerland, Austria, Bulgaria, Canada, Czechia, Slovakia
National and Kapodistrian University of Athens
University General Hospital of Heraklion; Naval Hospital, Athens; Silesian Centre... and other collaborators

Completed

Impact of Predilatation Between Self-expanding Valves (DIRECTII)

Aortic Stenosis

Greece
Boston Scientific Corporation

Completed

ACURATE Prime XL Human Feasibility Study

Aortic Stenosis

Australia
Edwards Lifesciences

Completed

SOURCE 3: Observational Study to Evaluate Safety and Performance of SAPIEN 3 THV System in Real Life Practice (SOURCE 3)

Aortic Stenosis

United Kingdom, Denmark, Germany, Switzerland, France, Netherlands, Finland, Italy, Slovakia, Spain
Peijia Medical Technology (Suzhou) Co., Ltd.
General Hospital of Shenyang Military Region; Shanghai Zhongshan Hospital; China... and other collaborators

Completed

Safety and Efficacy of TaurusOne® Transcatheter Aortic Valve Replacement System With Retrievable Delivery Catheter System

Aortic Stenosis

China
Symetis SA

Terminated

CHANGE Neo™ TA Registry With ACURATE Neo™ Aortic Bioprosthesis and ACURATE Neo™ TA Transapical Delivery System

Aortic Stenosis

Germany
Keystone Heart

Completed

DEFLECT I: Keystone Heart Embolic Deflection Trial

Aortic Stenosis
Boston Scientific Corporation

Completed

Performance and Safety of the Lotus™ Valve With a FLEXible Delivery System

Aortic Stenosis

Australia
Montefiore Medical Center

Withdrawn

Conscious Sedation vs General Anesthesia in TAVR Patients

Aortic Stenosis
Boston Scientific Corporation

Completed

Self-Centering Guide Catheter Feasibility Study

Aortic Stenosis

United States
Medtronic Cardiovascular
Medtronic

Completed

The Medtronic CoreValve™ Evolut R™ CE Mark Clinical Study

Aortic Stenosis

New Zealand, United Kingdom, Australia
Symetis SA

Completed

ACURATE TA™ Valve Implantation Registry: SAVI 2 (TA-SAVI2)

Aortic Stenosis

Germany, Austria, Italy, Switzerland
Aarhus University Hospital Skejby

Completed

Transcatheter Heart Valve (THV) Sizing and Leakage After Transcatheter Aortic Valve Implantation (TAVI) Before and After Establishing Routine Preprocedure Multi Slice Computerized Tomography (MSCT) Aortic Assessment. A Retrospective Registry Study

Aortic Stenosis

Denmark
University of Edinburgh
British Heart Foundation

Completed

The Role of Myocardial Fibrosis in Patients With Aortic Stenosis

Aortic Stenosis

United Kingdom
Hospital de Meixoeiro

Completed

Frailty and Mortality in Older Old With Severe Aortic Stenosis (SAS-frailty)

Aortic Stenosis

Spain
Catholic University of the Sacred Heart
Francesca Graziani, MD; Stefano Cangemi, MD

Recruiting

LUS in Aortic Stenosis Patients Undergoing TAVR

Transcatheter Aortic Valve Replacement | Lung Ultrasound | Severe Aortic Valve Stenosis | Pulmonary Congestion

Italy
Charles University, Czech Republic

Unknown

Risk Factors Associated With Calcification of the Aortic Valve

Aortic Stenosis | Aortic Sclerosis

Czech Republic
EnCompass Technologies, Inc.

Not yet recruiting

U.S. Multicenter Feasibility Trial of the F2 Filter and Delivery System for Embolic Protection During TAVR

Aortic Stenosis
EnCompass Technologies, Inc.

Recruiting

Multicenter Feasibility Trial of the F2 Filter and Delivery System for Embolic Protection During TAVR

Aortic Stenosis

Australia
Oslo University Hospital
University of Oslo

Recruiting

AntiCoagulation Versus AcetylSalicylic Acid After Transcatheter Aortic Valve Implantation (ACASA-TAVI)

Aortic Stenosis

Norway
Medtronic Cardiac Surgery
Medtronic

Active, not recruiting

PERIGON Pivotal Trial (PERIGON)

Aortic Stenosis

France, United States, Germany, Switzerland, Canada, Netherlands, Italy, United Kingdom
Medical University Innsbruck
Klinikum Wels-Grieskirchen; Johannes Kepler University of Linz

Completed

Cardiac Magnetic Resonance Imaging Versus Computed Tomography to Guide Transcatheter Aortic Valve Replacement (TAVR-CMR)

Aortic Stenosis

Austria
Medstar Health Research Institute
Medtronic Cardiovascular

Active, not recruiting

CoreValve Evolut Pro Prospective Registry

Aortic Stenosis

United States
Yale University

Completed

Association of Type of Anesthetic and Outcomes in Transfemoral Aortic Valve Replacement

Aortic Stenosis
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Transmural Systems Transcaval Closure Device for Transcaval Access Ports During Transcatheter Aortic Valve Replacement

Aortic Stenosis

United States
Medtronic Cardiovascular

Completed

Medtronic CoreValve Evolut R U.S. Clinical Study

Aortic Stenosis

United States
Cedars-Sinai Medical Center

Active, not recruiting

18-F Sodium Fluoride (18F-NaF) PET for the Assessment of Bioprosthetic Aortic Valve Durability and Outcomes

Aortic Stenosis

United States
Centre Hospitalier Universitaire de Besancon

Completed

Impact of Pre-procedure Cognitive Status on Outcome at 3 Months After Transcatheter Aortic Valve Implantation (TAVI-Geriatrie)

Aortic Stenosis

France
Fundación EPIC

Active, not recruiting

PRospective Evaluation Complementing Investigation With Acurate Neo Device (PRECISA)

Aortic Stenosis

Spain
Leipzig Heart Institute GmbH
Charite University, Berlin, Germany; University Hospital Schleswig-Holstein... and other collaborators

Unknown

SecOnd-generation seLf-expandable Versus Balloon-expandable Valves and gEneral Versus Local Anesthesia in TAVI (SOLVE-TAVI)

Aortic Stenosis

Germany
Second Xiangya Hospital of Central South University
Xiangya Hospital of Central South University; West China Hospital; The Third... and other collaborators

Unknown

Cerebral Lesion and Neurocognitive Status Changes After TAVR (CLEVER-TAVR)

Aortic Stenosis

China
Baylor Research Institute

Completed

Non-contrast 3-dimensional Cardiac Magnetic Resonance Imaging

Aortic Stenosis

United States
Edwards Lifesciences

Completed

EDWARDS INTUITY Elite Valve System (MISSION)

Aortic Stenosis | Aortic Valve Disease

Spain, Germany, United Kingdom, Austria, Denmark, France, Italy, Luxembourg, Netherlands
University of California, Davis

Completed

Balloon Aortic Valvuloplasty During Surgical Aortic Valve Replacement (BAV-SAVR)

Aortic Stenosis

United States
Sahlgrenska University Hospital, Sweden

Completed

Microembolic Signals and Cerebrospinal Fluid Markers of Neuronal Damage After Surgical Aortic Valve Replacement

Aortic Stenosis

Sweden
Institut für Pharmakologie und Präventive Medizin

Completed

ROUTE Registry Of the Utilisation of the Transaortic (Tao) TAVI Approach Using the Edwards Sapien XT Valve (ROUTE)

Aortic Stenosis

Netherlands, France, Austria, Finland, Germany, Italy, Norway, Poland, United Kingdom
Hadassah Medical Organization

Withdrawn

Neuropsychological Testing in Patients Undergoing Transvascular Aortic Valve Implantation (TAVIPSYCH)

Aortic Stenosis

Israel
Hadassah Medical Organization

Unknown

Temporary Pacemaker in Transcatheter Aortic Valve Implantation Patients (PAMIT)

Aortic Stenosis
University Hospital, Grenoble

Completed

Interest of Cardiac Computed Tomography to Optimize and Improve the Procedure of TAVI (CT-TAVI)

Aortic Stenosis

France
Charles University, Czech Republic
Ministry of Health, Czech Republic

Completed

Clinical Significance of Collagen Metabolism Changes in Left Cardiac Ventricle

Aortic Stenosis

Czech Republic
Barts & The London NHS Trust
Imperial College London

Not yet recruiting

RESTORE-TAVI Pilot

Aortic Stenosis | Frailty
Insel Gruppe AG, University Hospital Bern

Not yet recruiting

Involvement of the Gut Microbiota in Calcified Aortic Stenosis (Gut-CAS)

Aortic Stenosis | Gastrointestinal Microbiome | Metabolomics
Royal Brompton & Harefield NHS Foundation Trust

Withdrawn

A Comparison of Advanced Imaging Techniques in Aortic Stenosis (AIm-AS)

Aortic Stenosis

United Kingdom
Deutsches Herzzentrum Muenchen

Recruiting

The Prospecive OBSERVational Munich Interventional MITRAl-Valve Registry (OBSERV-MITRA)

Mitral Valve Stenosis | Mitral Valve Regurgitation | Tricuspid Valve Regurgitation

Germany
Novartis Pharmaceuticals

Recruiting

A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis

Aortic Stenosis

Switzerland, Canada, Israel, United States, United Kingdom
Centre de Recherche de l'Institut Universitaire...

Completed

Erythropoietin + Iron Therapy for Anemic Patients Undergoing Aortic Valve Replacement (EPICURE)

Anemia | Aortic Stenosis

Canada

Clinical Trials on Mitral Insufficiency and Aortic Stenosis

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