Clinical Trials on Pleural Diseases in United Kingdom

Total 147308 results

European Organisation for Research and Treatment...

Completed

Bortezomib and Cisplatin as First-Line Therapy in Treating Patients With Malignant Mesothelioma

Malignant Mesothelioma

United Kingdom
Polaris Group

Terminated

Ph 1 Study in Subjects With Tumors Requiring Arginine to Assess ADI-PEG 20 With Pemetrexed and Cisplatin (TRAP)

Glioma | Hepatocellular Carcinoma | Uveal Melanoma | Sarcomatoid Carcinoma | Pleural Mesothelioma Malignant Advanced | Peritoneal Mesothelioma Malignant Advanced | Non-squamous Non-small Cell Lung Carcinoma

United States, United Kingdom
Brigham and Women's Hospital
General Electric

Completed

Evaluation of a Pocket-Sized Ultrasound Device As an Aid to the Physical Examination

Pleural Effusion | Splenomegaly

United States
Beth Israel Deaconess Medical Center

Completed

Fibrinolysis Compared to Thoracoscopy for Pleural Infection

Pleural Diseases | Pleural Infection

United States
O'Brien, Jeana D., MD, FACP, FCCP
Genentech, Inc.; Texas A&M University; Scott and White Hospital & Clinic; Scott...

Unknown

Alteplase for Treatment of Empyema and Complicated Parapneumonic Effusion

Pleural Effusion | Empyema

United States
University of Washington
National Cancer Institute (NCI)

Completed

Imatinib Mesylate and Paclitaxel in Treating Older Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer

Stage IIIB Non-small Cell Lung Cancer | Recurrent Non-small Cell Lung Cancer | Stage IV Non-small Cell Lung Cancer | Malignant Pleural Effusion

United States
Dana-Farber Cancer Institute
Brigham and Women's Hospital

Completed

Pleurectomy/Decortication Followed by Intrathoracic/Intraperitoneal Heated Cisplatin for Malignant Pleural Mesothelioma

Malignant Pleural Mesothelioma | Pleural Mesothelioma

United States
National Cancer Institute (NCI)

Completed

Bortezomib Plus Gemcitabine and Carboplatin in Treating Patients With Advanced or Recurrent Non-Small Cell Lung Cancer

Stage IIIB Non-small Cell Lung Cancer | Recurrent Non-small Cell Lung Cancer | Stage IV Non-small Cell Lung Cancer | Malignant Pleural Effusion

United States
Dana-Farber Cancer Institute
Brigham and Women's Hospital

Terminated

Pleurectomy/Decortication With Intraoperative Intrathoracic/Intraperitoneal Heated Cisplatin With Sodium Thiosulfate

Malignant Pleural Mesothelioma | Pleural Mesothelioma

United States
Dana-Farber Cancer Institute
Brigham and Women's Hospital

Completed

Extrapleural Pneumonectomy With Intraoperative Intrathoracic/Intraperitoneal Heated Cisplatin With Amifostine and Sodium Thiosulfate

Malignant Pleural Mesothelioma | Pleural Mesothelioma

United States
Medical Research Council

Completed

Active Symptom Control With or Without Chemotherapy in Treating Patients With Malignant Pleural Mesothelioma

Malignant Mesothelioma

United Kingdom
Tulane University

Completed

Fibrinolysis Compared to Thoracoscopy for Pleural Infection

Pleural Diseases | Pleural Infection | Empyema | Parapneumonic Effusion

United States
University of California, Los Angeles

Withdrawn

Tunneled Pleural Catheters for Refractory Effusions Attributed to Congestive Heart Failure (TREAT-CHF) Trial (TREAT-CHF)

Congestive Heart Failure | Shortness of Breath | Pleural Effusions, Chronic

United States
University of Chicago

Recruiting

A Pilot Window-Of-Opportunity Study of the Anti-PD-1 Antibody Pembrolizumab in Patients With Resectable Malignant Pleural Mesothelioma

Pleural Mesothelioma

United States
Ascension South East Michigan
Fujirebio Diagnostics, Inc.; International Association of Heat and Frost Insulators... and other collaborators

Terminated

Mesothelioma Early Detection by VOCs (MED-VOC)

Pleural Mesothelioma | Asbestos Exposure | Pleural Plaque

United States
Fox Chase Cancer Center
National Cancer Institute (NCI)

Terminated

Genetic Sequencing-Informed Targeted Therapy in Treating Patients With Stage IIIB-IV Non-small Cell Lung Cancer

Stage IIIB Non-small Cell Lung Cancer | Recurrent Non-small Cell Lung Cancer | Stage IV Non-small Cell Lung Cancer | Malignant Pleural Effusion | Malignant Pericardial Effusion

United States
University of Glasgow

Completed

Radiation Therapy in Preventing Metastatic Cancer in Patients Who Have Diagnostic Procedures to Identify Malignant Mesothelioma

Malignant Mesothelioma | Perioperative/Postoperative Complications

United Kingdom
Abramson Cancer Center at Penn Medicine

Recruiting

Phase II Trial of Radical Pleurectomy With or Without Intraoperative PDT for Malignant Pleural Mesothelioma (MPM-PDT)

Epitheliod Malignant Pleural Mesothelioma

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Transarterial Chemoembolization for the Treatment of Lung Cancer

Lung Non-Small Cell Carcinoma | Mediastinal Neoplasm | Pleural Neoplasm

United States
Jonsson Comprehensive Cancer Center

Terminated

Accelerated Hypofractionated Radiation Therapy Immediately Before Surgery in Treating Patients With Malignant Pleural Mesothelioma

Pleural Epithelioid Mesothelioma | Pleural Malignant Mesothelioma

United States
University of Chicago

Withdrawn

A Phase Ib Trial of a Maintenance Multipeptide Vaccine (S-588210) in Patients With Unresectable Malignant Pleural Mesothelioma Without Progression After First-Line Chemotherapy

Malignant Pleural Mesothelioma (MPM)

United States
Swedish Medical Center

Completed

Management of Pleural Space Infections

Empyema, Pleural | Parapneumonic Effusion

United States
National Cancer Institute (NCI)

Active, not recruiting

Atezolizumab, Pemetrexed Disodium, Cisplatin, and Surgery With or Without Radiation Therapy in Treating Patients With Stage I-III Pleural Malignant Mesothelioma

Biphasic Mesothelioma | Epithelioid Mesothelioma | Stage III Pleural Malignant Mesothelioma AJCC v7 | Stage I Pleural Malignant Mesothelioma AJCC v7 | Stage IA Pleural Malignant Mesothelioma AJCC v7 | Stage IB Pleural Malignant Mesothelioma AJCC v7 | Stage II Pleural Malignant Mesothelioma AJCC...

United States
University College, London
Cancer Research UK

Recruiting

TRAcking Thoracic Cancer Evolution Through Therapy (Rx) EVO

Small Cell Lung Cancer | Lung Cancer, Non-small Cell | Pleural Mesothelioma

United Kingdom
National Cancer Institute (NCI)

Terminated

Tivantinib in Treating Patients With Previously Treated Malignant Mesothelioma

Epithelioid Mesothelioma | Sarcomatoid Mesothelioma | Stage IV Pleural Mesothelioma | Recurrent Malignant Mesothelioma | Stage II Pleural Mesothelioma | Stage III Pleural Mesothelioma

United States
ETOP IBCSG Partners Foundation
Hoffmann-La Roche

Active, not recruiting

BEAT-meso: Bevacizumab and Atezolizumab in Malignant Pleural Mesothelioma (BEAT-meso)

Pleural Mesothelioma Malignant Advanced

Switzerland, United Kingdom, Belgium, Spain, France, Italy
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Treatment With Octreotide in Patients With Lymphangioleiomyomatosis

Ascites | Lymphangioleiomyomatosis | Lymphangiomyomas | Pleural Effusions

United States
University of Minnesota

Withdrawn

Determination of Pneumothorax Post Lung Biopsy

Pneumothorax

United States
Children's Healthcare of Atlanta

Terminated

Chylothorax Following Heart Surgery

Chylothorax

United States
Memorial Sloan Kettering Cancer Center

Completed

Ph I:Bevacizumab + Chemotherapy in Pts w/Malig Pleural Effusion Due to Adv NSCLC

Carcinoma, Non-Small-Cell Lung

United States
Papworth Hospital NHS Foundation Trust

Completed

Video-Assisted Surgery or Talc Pleurodesis in Treating Patients With Malignant Mesothelioma (MesoVATS)

Metastatic Cancer | Malignant Mesothelioma

United Kingdom
NYU Langone Health

Completed

Data Visualization of Kidney and Prostate Tumors Using Routine Pre-Operative Imaging, 3D Printed, and 3D Virtual Reality Models

Pleural Effusion

United States
H. Lee Moffitt Cancer Center and Research Institute
Eli Lilly and Company; Aventis Pharmaceuticals

Completed

The 'MADe IT' Clinical Trial: Molecular Analyses Directed Individualized Therapy for Advanced Non-Small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung

United States
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Completed

Nintedanib in Treating Patients With Malignant Pleural Mesothelioma That Is Recurrent

Recurrent Pleural Malignant Mesothelioma | Stage IV Pleural Mesothelioma

United States
The Leeds Teaching Hospitals NHS Trust

Unknown

Self-taken Penile Meatal Swabs for Chlamydia, Gonorrhoea and Mycoplasma Genitalium Detection (Me-swab)

Sexually Transmitted Diseases, Bacterial

United Kingdom
Novartis Pharmaceuticals

Completed

Non-small Cell Lung Cancer Registry

Pleural Effusion, Malignant | Non-Small-Cell Lung Cancer

United States
Bayer

Completed

First-in-human Study of BAY2287411 Injection, a Thorium-227 Labeled Antibody-chelator Conjugate, in Patients With Tumors Known to Express Mesothelin

Advanced Recurrent Malignant Pleural Epithelioid Mesothelioma | Advanced Recurrent Malignant Peritoneal Epithelioid Mesothelioma | Advanced Recurrent Serous Ovarian Cancer | Advanced Pancreatic Ductal Adenocarcinoma (Optional, Dose Expansion, Not Initiated)

United States, Sweden, Netherlands, United Kingdom, Finland
Roswell Park Cancer Institute
Lumeda,Inc.

Active, not recruiting

Light Dosimetry for Photodynamic Therapy With Porfimer Sodium in Treating Participants With Malignant Mesothelioma or Non-Small Cell Lung Cancer With Pleural Disease Undergoing Surgery

Malignant Mesothelioma | Non-Small Cell Lung Carcinoma | Pleural Disorder

United States
Amphera BV
TMC Pharma

Completed

DENdritic Cell Immunotherapy for Mesothelioma (DENIM)

Mesothelioma

Netherlands, France, United Kingdom, Belgium, Italy
Verastem, Inc.

Terminated

A Phase 1 Dose Escalation Study of VS-5584 Administered in Combination With VS-6063, in Subjects With Relapsed Malignant Mesothelioma

Relapsed Malignant Mesothelioma

United States, United Kingdom
Denver Health and Hospital Authority

Completed

Treatment of Complicated Parapneumonic Effusion With Fibrinolytic Therapy Versus VATs Decortication

Coagulopathy | Empyema, Pleural | Parapneumonic Effusion

United States
University of Leeds
The Leeds Teaching Hospitals NHS Trust; Iqvia Pty Ltd

Completed

eRAPID: Online Symptom Reporting in Lung Cancer

Thoracic Cancer | Non-small Cell Lung Cancer | Small-cell Lung Cancer | Pleural Mesothelioma

United Kingdom
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Recruiting

Testing the Addition of Immunotherapy Before Surgery for Patients With Sarcomatoid Mesothelioma

Pleural Biphasic Mesothelioma | Pleural Sarcomatoid Mesothelioma

United States
National Cancer Institute (NCI)

Completed

Phase I Study of Gene Induction Mediated by Sequential Decitabine/Depsipeptide Infusion With or Without Concurrent Celecoxib in Subjects With Pulmonary and Pleural Malignancies

Non-Small-Cell Lung Carcinoma | Cancers of Non-thoracic Origin With Metastases to the Lungs or Pleura | Advanced Esophageal Cancers | Primary Small Cell Lung Cancers | Pleural Mesotheliomas

United States
University of Oklahoma

Recruiting

Use of Endobronchial Ultrasound Scope (EBUS) Transducer to Identify Pneumothorax-A Feasibility Study

Pneumothorax

United States
National Cancer Institute (NCI)

Completed

Docetaxel With Either Cetuximab or Bortezomib as First-Line Therapy in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer

Stage IIIB Non-small Cell Lung Cancer | Recurrent Non-small Cell Lung Cancer | Stage IV Non-small Cell Lung Cancer | Squamous Cell Lung Cancer | Adenocarcinoma of the Lung | Large Cell Lung Cancer | Malignant Pleural Effusion | Adenosquamous Cell Lung Cancer

United States
Morphotek

Terminated

Study of the Safety and Efficacy of Amatuximab in Combination With Pemetrexed and Cisplatin in Subjects With Unresectable Malignant Pleural Mesothelioma (MPM) (ARTEMIS)

Mesothelioma, Malignant

France, United Kingdom, United States, Germany, Australia, Italy
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; Sheffield Hallam University

Not yet recruiting

Exercise to Boost Immunity in Advanced Cancer (BICEP)

Pancreatic Cancer | Mesothelioma; Lung

United Kingdom
Johns Hopkins University

Recruiting

Pleural Manometry for the Characterization of Spontaneous and Tension Pneumothorax

Pneumothorax | Tension Pneumothorax

United States
University of Rochester

Withdrawn

Duration of Chest Tube Suction in Traumatic Pneumothorax

Traumatic Pneumothorax

United States

Clinical Trials on Pleural Diseases in United Kingdom

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