Clinical Trials on Severe Symptomatic Aortic Stenosis

Total 1184 results

Sheba Medical Center

Suspended

Clinical Outcome of Patients With Low-gradient Severe Aortic Stenosis

Aortic Stenosis

Israel
Symetis SA

Completed

ACURATE Neo™ TA Delivery System in Patient With Severe Aortic Stenosis

Aortic Stenosis

Germany
Avicena LLC

Completed

Vivio AS (Aortic Stenosis) Detection Study

Aortic Stenosis

United States
Symetis SA

Completed

ACURATE Neo™ Aortic Bioprosthesis for Implantation Using the ACURATE TA™ LP Transapical Delivery System in Patients With Severe Aortic Stenosis (TALP-FIM)

Aortic Stenosis

Germany
University Hospital, Toulouse
Medtronic

Completed

Study of Platelet Activation by Severe Aortic Stenosis and Its Correction by Transcatheter Aortic Valve Implantation (TAVI)

Aortic Stenosis

France
Mayo Clinic
American Heart Association

Completed

Assessment of Myocardial Tissue Damage in Aortic Stenosis

Aortic Stenosis

United States
University Hospitals, Leicester

Completed

Microvascular Dysfunction in Aortic Stenosis (PRIMID-AS)

Aortic Stenosis

United Kingdom
Thebiosignals.com

Completed

Risk Prediction in Aortic Stenosis (PREDICT-AS)

Aortic Stenosis

Germany
The Cleveland Clinic
National Space Biomedical Research Institute

Terminated

Three Dimensional Imaging and Wireless Technologies to Enhance Medical Care in Space

Aortic Stenosis | Aortic Valve Insufficiency

United States
Centre Hospitalier Universitaire, Amiens

Withdrawn

Interest of Pulse Wave Velocity Measurement as a Predictor of Severity of Aortic Stenosis (VOPRABIO)

Aortic Stenosis | Pulse Wave

France
Lahey Clinic
Tufts Medical Center

Withdrawn

Ventricular Remodeling In Patients With Aortic Stenosis Assessed Echocardiography

Aortic Stenosis

United States
IRCCS SYNLAB SDN
Federico II University

Recruiting

Potential Role of Sirtuins as Epigenetic Biomarkers of the Patient With Atherosclerosis or Calcific Aortic Stenosis

Atherosclerosis and Calcific Aortic Stenosis With and Without Diabetes

Italy
Massachusetts General Hospital
Edwards Lifesciences

Recruiting

Electronic Physician Notification to Facilitate the Recognition and Management of Severe Aortic Stenosis: The DETECT AS Trial (DETECT AS)

Aortic Stenosis

United States
Beijing Anzhen Hospital
Beijing Municipal Health Commission

Recruiting

Effect of PCSK9 Inhibitors on Calcific Aortic Valve Stenosis (EPISODE)

Aortic Stenosis

China
Institut universitaire de cardiologie et de pneumologie...
Odense University Hospital

Recruiting

Angiotensin Receptor Blockers in Aortic Stenosis (ARBAS)

Aortic Stenosis

Denmark, Canada
University of British Columbia
Edwards Lifesciences

Recruiting

Standardized Invasive Hemodynamics for Elevated Gradients Post TAVR (DISCORDANCE TAVR)

Aortic Stenosis | Aortic Valve Stenosis

United States, Canada
Shanghai MicroPort CardioFlow Medtech Co., Ltd.

Recruiting

VitaFlow™ II Transcatheter Aortic Valve System Pre-market Trial

Aortic Stenosis

China
Organon and Co

Completed

An Investigational Drug on Clinical Outcomes in Patients With Aortic Stenosis (Narrowing of the Major Blood Vessel of the Heart)(MK-0653A-043 AM4)(COMPLETED)

Aortic Stenosis
University of Leipzig
National University of Ireland, Galway

Active, not recruiting

PROVE ACURATE neo2™ - Post Market Safety and Performance Surveillance in Aortic Stenosis (PROVE)

Aortic Stenosis

Germany, Switzerland, Sweden, France
American College of Radiology
Pennsylvania Department of Health

Completed

Cardiac MRI for Severe Aortic Stenosis

Aortic Stenosis

United States
Opsens, Inc.

Terminated

OpSens PRIME CLASS

Aortic Stenosis

Spain
Hospital do Coracao

Active, not recruiting

Treatment of Aortic Stenosis in Brazil: Cost-Utility Analysis of TAVI vs SAVR (TEAm-BR)

Aortic Stenosis

Brazil
Symetis SA

Completed

ACURATE Neo™ AS Aortic Bioprosthesis for Implantation Using the ACURATE neoTM AS TF Transfemoral Delivery System in Patients With Severe Aortic Stenosis

Aortic Stenosis

Germany, Denmark, Switzerland
Clinical Centre of Serbia

Completed

Aortic Valve Replacement Versus Conservative Treatment in Asymptomatic Severe Aortic Stenosis (AVATAR)

Aortic Stenosis

Ireland, Czechia, Lithuania, Belgium, Croatia, France, Italy, Poland, Serbia
Erasme University Hospital

Suspended

Aortic Stenosis Evaluated Via Modern Ballistocardiography and Seismocardiography (TAVI)

Aortic Stenosis

Belgium
University Hospital Southampton NHS Foundation...

Completed

Reactive Oxygen Species Following Aortic Valve Replacement (ROS)

Aortic Stenosis

United Kingdom
Baylor Research Institute

Completed

Prospective Balloon Aortic Valvuloplasty (BAV)

Aortic Stenosis

United States
United States Naval Medical Center, San Diego
The Geneva Foundation; 3M

Completed

Correlation of Auscultatory Severity of Aortic Stenosis With Trans Thoracic Echocardiography (Cassette)

Aortic Stenosis

United States
Nantes University Hospital

Completed

Genetics of Aortic Stenosis: From Family Forms to the Common Forms

Aortic Stenosis

France
Aarhus University Hospital

Completed

Myocardial Efficiency of the Left Ventricle in Asymptomatic Patients With Aortic Valve Stenosis - a Prognostic Marker and a Target for Intervention? (MELVAS)

Aortic Stenosis

Denmark
University of Manitoba
Health Sciences Centre Foundation, Manitoba; St. Boniface Hospital

Completed

The Effects of High Spinal Anesthesia on Heart Function, Stress Response and Pain Control in Aortic Valve Surgery

Aortic Stenosis

Canada
Haukeland University Hospital

Completed

Transcatheter Aortic Valve Implantation in Western NORway (TAVI-NOR)

Hypertension | Aortic Stenosis
Second Affiliated Hospital, School of Medicine,...

Recruiting

Down Sizing Strategy (HANGZHOU Solution) vs Standard Sizing Strategy TAVR in Bicuspid Aortic Stenosis (Type 0) (TAILOR-TAVR)

Aortic Stenosis With Bicuspid Valve

China
Second Affiliated Hospital, School of Medicine,...
The First Affiliated Hospital of Nanchang University; Chinese PLA General Hospital and other collaborators

Recruiting

HANGZHOU Solution in Bicuspid AS Undergoing TAVR

Aortic Stenosis | Aortic Stenosis With Bicuspid Valve

China
Heinrich-Heine University, Duesseldorf

Recruiting

Phenotyping Heterogeneity and Regionality of the Aorta (PHaRAo)

Aortic Stenosis | Aortic Aneurysm | Aortic Disease | Large Artery Stiffness

Germany
Spanish Society of Cardiology
Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III

Active, not recruiting

Dapagliflozin After Transcatheter Aortic Valve Implantation (DapaTAVI)

Aortic Stenosis | Transcatether Aortic Valve Implantation

Spain
North Florida Foundation for Research and Education
Malcom Randall VA Medical Center

Completed

Pressure Assessment to Improve Outcomes After TAVR: a Registry

Quality of Life | Hypertension | Heart Failure With Preserved Ejection Fraction | Aortic Stenosis, Calcific

United States
The Cleveland Clinic

Recruiting

Comparative Imaging Assessment of Valvular Heart Disease

Aortic Stenosis | Aortic Regurgitation | Valve Heart Disease

United States
University of Edinburgh
British Heart Foundation

Completed

The Role of Myocardial Fibrosis in Patients With Aortic Stenosis

Aortic Stenosis

United Kingdom
Hospital de Meixoeiro

Completed

Frailty and Mortality in Older Old With Severe Aortic Stenosis (SAS-frailty)

Aortic Stenosis

Spain
Minneapolis Heart Institute Foundation

Recruiting

Racial and Economic Disparities and Unmet Needs in Patients With Severe Aortic Valvular Disease

Aortic Valve Stenosis | Disparities in Treatment of Aortic Valve Stenosis

United States
Centre Hospitalier Universitaire, Amiens

Recruiting

Valvular Aortic Stenosis Prognosis Study (EPRAoV)

Morality

France
Imperial College Healthcare NHS Trust

Suspended

TAVI and Gender Outcomes Aortic Stenosis Undergoing Transfemoral Transcatheter Aortic Valve Implantation.

Aortic Stenosis | Surgery | Gender
Oslo University Hospital

Completed

Comparison of Blood and Crystalloid Cardioplegia

Aortic Stenosis | Myocardial Protection

Norway
Abbott Medical Devices

Recruiting

Post-Market Clinical Follow Up Study With Navitor Valve (VISTA)

Aortic Stenosis

Spain, Italy, France, Germany, Portugal, Switzerland
AUSL Romagna Rimini

Recruiting

Transfemoral Transcatheter Aortic Valve Implementation at Hospital Without On-site Cardiac Surgery: Early Clinical Outcome in Patients With Prohibitive Surgical Risk.

Aortic Stenosis

Italy
Medtronic Cardiac Surgery
Medtronic

Completed

PERIGON Japan Trial

Aortic Stenosis

Japan
Corcym S.r.l

Terminated

Sorin Universal REgistry on Aortic Valve Replacement (SURE-AVR)

Aortic Stenosis | Aortic Valve Disease

Belgium, France, Spain, Israel, United Kingdom, Australia, United States, Netherlands, Germany, Italy, Singapore, Switzerland, Austria, Bulgaria, Canada, Czechia, Slovakia
National and Kapodistrian University of Athens
University General Hospital of Heraklion; Naval Hospital, Athens; Silesian Centre... and other collaborators

Completed

Impact of Predilatation Between Self-expanding Valves (DIRECTII)

Aortic Stenosis

Greece
Boston Scientific Corporation

Completed

ACURATE Prime XL Human Feasibility Study

Aortic Stenosis

Australia

Clinical Trials on Severe Symptomatic Aortic Stenosis

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