Clinical Trials on Symptomatic Atherosclerosis

Total 3400 results

National Cerebral and Cardiovascular Center

Unknown

Atheroma Progression and Vulnerability Under Continuous Glucose Monitoring (OPTIMAL)

Coronary Atherosclerosis

Japan
University of Chicago
Pfizer

Terminated

Asymptomatic Colonization With S. Aureus After Therapy With Linezolid or Clindamycin for Acute Skin Infections

Abscess | Skin Diseases, Bacterial

United States
Xiang Xie
Xinjiang Medical University

Not yet recruiting

Study on the Composite Endpoint Event of PCSK9 Inhibitor in Patients With Very High Risk of ASCVD and Cancer

Cancer | Atherosclerotic Cardiovascular Disease | ASCVD | Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitor
Icahn School of Medicine at Mount Sinai
Massachusetts General Hospital; National Heart, Lung, and Blood Institute (NHLBI) and other collaborators

Completed

Cardiovascular Inflammation Reduction Trial - Inflammation Imaging Study (CIRT)

Atherosclerotic Cardiovascular Disease | Vascular Inflammation

United States, Canada
AstraZeneca
The Cleveland Clinic; IQVIA RDS Inc.

Completed

Outcomes Study to Assess STatin Residual Risk Reduction With EpaNova in HiGh CV Risk PatienTs With Hypertriglyceridemia (STRENGTH)

Eligible Men or Women Considered High Risk for Atherosclerotic Cardiovascular Disease (CVD)

United States, Belgium, Italy, Netherlands, Denmark, Taiwan, Poland, Russian Federation, Korea, Republic of, Hungary, United Kingdom, China, New Zealand, Czechia, Australia, South Africa, Ukraine, Japan, Canada, Mexico, Lithuania, Estoni...
Erasmus Medical Center
Fondazione Policlinico Universitario Agostino Gemelli IRCCS; Dr Cipto Mangunkusumo...

Recruiting

Carbapenem-resistant Pseudomonas Aeruginosa: the SAMPAN Study. (SAMPAN)

Nosocomial Infection | Pseudomonas Aeruginosa | Colonization, Asymptomatic

Netherlands, Indonesia, Italy
Aristotle University Of Thessaloniki

Completed

Diagnosis and Therapy of Vulnerable Atherosclerotic Plaque

Stroke | Metabolic Syndrome | Type 2 Diabetes | Carotid Atherosclerosis

Greece
Kendall Healthcare Group, Ltd.

Completed

Urinalysis Results in Healthy Individuals

Asymptomatic Bacteriuria | Asymptomatic Pyuria

United States
Hôpital Européen Marseille

Completed

Evaluation of Vaginal Self-sampling Diagnostic Performances to Identify Genital Infections

Asymptomatic Infections | Genital Infection

France
Novo Nordisk A/S

Completed

A Research Study Looking at the Effect of Food Intake on How the Medicine NN0385-0434 Behaves in the Body of Healthy Participants

Healthy Volunteers | Elevated Cholesterol | Established Atherosclerotic Cardiovascular Disease (ASCVD) or ASCVD Risk

Germany
Brigham and Women's Hospital

Terminated

The Effect(s) of Sevelamer Carbonate (Renvela) on Atherosclerotic Plaque Inflammation Judged by FDG-PET Scan

Inflammation | Cardiovascular Disease | Atherosclerosis | Hyperphosphatemia | Dialysis

United States
Massachusetts General Hospital

Completed

Indocyanine Green Fluorescence Uptake in Human Carotid Artery Plaque (BRIGHT-CEA)

Atherosclerosis | Carotid Stenosis | Atherosclerotic Plaque

United States
Assistance Publique - Hôpitaux de Paris
Solvay Pharmaceuticals; French Health Products Safety Agency; FRM

Terminated

Dose Effects of Hormone Therapy (Two Doses of Estradiol Associated to Progesterone) on Inflammatory Markers (THS)

Healthy Symptomatic Menopausal Women

France
Singapore National Eye Centre
National Medical Research Council (NMRC), Singapore

Unknown

Asymptomatic Narrow Angles - Laser Iridotomy Study; Multicentric RCT

Asymptomatic Narrow Angles | Primary Angle Closure Suspects

Singapore
City of Hope Medical Center
National Cancer Institute (NCI); California Institute for Regenerative Medicine...

Active, not recruiting

Analysis of Coronavirus Disease 19 (COVID-19) Convalescent Plasma

Asymptomatic COVID-19 Infection Laboratory-Confirmed | Symptomatic COVID-19 Infection Laboratory-Confirmed

United States
Korea University Guro Hospital

Recruiting

Concurrent OCT and FFR-guided PCI in CAD (OPTICARE-CAD)

Coronary Artery Disease | Image | Atheroscleroses, Coronary

Korea, Republic of
Zimmer Biomet

Completed

Performance of the Hedrocel(R) Cervical Fusion Device

Symptomatic Cervical Disc Disease

United States
Boston Scientific Corporation

Completed

Symbiot III: A Prospective Randomized Trial Evaluating the Symbiot Covered Stent System in Saphenous Vein Grafts

Symptomatic Ischemic Saphenous Vein Graft Disease

United States, Canada
Leiden University Medical Center
Spaarne Gasthuis

Completed

Studying Respiratory Infections and Colonisation in Children Using Daily Minimally-invasive Nasal Sampling (SAMSAM)

Respiratory Tract; Infection, Upper (Acute) | Colonization, Asymptomatic

Netherlands
Jordan Collaborating Cardiology Group

Terminated

Tracking of Lipid Lowering Therapy in Jordan (JoLLA)

Dyslipidemias | Atherosclerotic Cardiovascular Disease

Jordan
Sheba Medical Center
Carmel Medical Center; University Hospital Goettingen; CVPath Institute Inc.

Unknown

Physical,Histological,and Genetic Analyses of Lipid-rich Atherosclerotic Plaques

Peripheral Vascular Diseases | Atherosclerosis | Aortic Aneurysm

Israel
Diagram B.V.
Isala; St. Jude Medical Nederland B.V.

Completed

Optical Coherence Tomography Morphologic and Fractional Flow Reserve Assessment in Diabetes Mellitus Patients (COMBINE)

Coronary Artery Disease | Diabetes Mellitus | Coronary Atheroscleroses

Netherlands
liuxingju
Beijing Municipal Science & Technology Commission

Unknown

Hybrid Operating Treatment of Coexistence of Intracranial Aneurysms and Cerebrovascular Stenosis (HOT-CIACS)

Intracranial Aneurysm | Atheroscleroses, Cerebral | Cerebrovascular Stenosis

China
Novartis Pharmaceuticals

Active, not recruiting

In Silico Study Assessing the Impact of Inclisiran on Major Adverse Cardiovascular Events in Patients With Established Cardiovascular Disease (SIRIUS)

Atherosclerotic Cardiovascular Disease

France
Esperion Therapeutics, Inc.

Completed

Assessment of the Long-Term Safety and Efficacy of Bempedoic Acid (CLEAR Harmony OLE)

Hypercholesterolemia | Atherosclerotic Cardiovascular Disease

United States
China National Center for Cardiovascular Diseases

Not yet recruiting

Natural History of Coronary Atherosclerosis (NASCENT)

Coronary Artery Disease Progression | Optical Coherence Tomography | Atherosclerotic Lesion | Radial Wall Strain
Korea University Guro Hospital

Recruiting

Comprehensive Assessment of Interconnection Between Brain Emotional Activity and Coronary Plaque Instability

Inflammation | Atherosclerosis | Acute Coronary Syndrome | Emotional Stress | Atherosclerosis, Coronary | Hematopoiesis | Atherosclerosis Coronary Artery With Angina Pectoris | Atheroma; Heart

Korea, Republic of
Greenwich Hospital
American Association of Neurological Surgeons

Completed

Neurosurgery Patient Outcomes in Treating Spinal Disorders (Neuropoint SD)

Symptomatic Lumbar Disc Herniation | Symptomatic Grade I Lumbar Spondylolisthesis

United States, Canada
Ionis Pharmaceuticals, Inc.

Active, not recruiting

A Study of Olezarsen (ISIS 678354) in Participants With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease, or With Severe Hypertriglyceridemia

Cardiovascular Diseases | Atherosclerosis | Hypertriglyceridemia

United States, Spain, Italy, Denmark, Hungary, Netherlands, Canada, France, Poland, Bulgaria, Czechia, Portugal, Slovakia, Norway
Brigham and Women's Hospital
Massachusetts General Hospital; Beth Israel Deaconess Medical Center

Terminated

Collar Immobilization Following a Posterior Cervical Laminectomy and Fusion

Cervical Spondylosis Symptomatic Neurological Compression

United States
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Active, not recruiting

Abbreviated Breast MRI and Digital Tomosynthesis Mammography in Screening Women With Dense Breasts

Asymptomatic

United States, Germany
Gazi University

Completed

The Immediate Effects of Kinesio-Taping on Scapular Muscle Endurance and Strength in Asymptomatic Subjects

Asymptomatic Subjects

Turkey
National Taiwan University Hospital

Unknown

High-intensity Focused Ultrasound (HIFU) for the Symptom Relief of Inoperable Abdominal Tumors (HIFU)

Symptomatic Abdominal Tumour

Taiwan
Northwell Health

Active, not recruiting

The Young Heart Study

Coronary Artery Disease | Atherosclerotic Cardiovascular Disease

United States
Sanofi
Regeneron Pharmaceuticals

Completed

ODYSSEY Outcomes: Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab

Atherosclerotic Cardiovascular Disease

China, Hong Kong, Austria, Bulgaria, Norway, Peru, France, Japan, Spain, Lithuania, Philippines, Israel, Belgium, Croatia, Poland, Hungary, Chile, Mexico, Latvia, Singapore, Switzerland, Colombia, Greece, Ukraine, Turkey, Finland, United States and more
Chinese University of Hong Kong

Completed

Anal Canal Functional Assessment Using EndoFLIP

Asymptomatic Condition | Faecal Incontinence

Hong Kong
Tabba Heart Institute
Getz Pharma

Recruiting

Pakistan Study of Premature Coronary Atherosclerosis in Young Adults (PAKSEHAT)

Stroke | Hypertension | Diabetes Mellitus, Type 2 | Atherosclerotic Plaque

Pakistan
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company

Completed

Treatment of High and Very High riSk Dyslipidemic pAtients for the PreveNTion of CardiOvasculaR Events (SANTORINI)

Cardiovascular Diseases | Dyslipidemia | Hypercholesterolemia | Atherosclerotic Cardiovascular Disease

Finland, Netherlands, Spain, Belgium, Sweden, Austria, United Kingdom, Switzerland, Denmark, France, Germany, Portugal, Italy, Ireland
Kimberly Blackwell

Terminated

Intrathecal Pertuzumab and Trastuzumab in Patients With New Untreated Asymptomatic or Low Symptomatic Brain Metastasis in HER2 Positive Breast Cancer

HER2 Positive Untreated Metastatic Breast Cancer | Asymptomatic or Low Symptomatic Brain Metastasis in Breast Cancer

United States
Aristotle University Of Thessaloniki

Unknown

Coronary Artery Geometry and the Severity of Coronary Atherosclerosis (GEOMETRY-CTA)

Coronary Artery Disease | Atherosclerosis | Stable Angina | Atherosclerotic Plaque

Greece
University Hospital, Clermont-Ferrand

Completed

Active Prevention of MSDs (Musculoskeletal Disorders, Upper and Spine Members) in the Context of Computer Screen Work (I-Preventive)

Symptomatic Musculoskeletal Diseases | Latent Musculoskeletal Diseases

France
Nantes University Hospital

Completed

Randomized Controlled Trial Comparing Transanal Doppler-guided Arterial Ligation With Mucopexy and Stapled Haemorrhoidopexy (LIGALONGO)

Symptomatic Haemorrhoidal Disease Requiring Surgical Management

France
Ionis Pharmaceuticals, Inc.

Completed

A Study of Olezarsen (Formerly Known as AKCEA-APOCIII-LRx) in Adults With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease (Established or at Increased Risk for), and/or With Severe Hypertriglyceridemia

Hypertriglyceridemia | Atherosclerotic Cardiovascular Disease | Severe Hypertriglyceridemia

United States, Canada
Celldex Therapeutics

Completed

A Single Dose Study of the Safety, Pharmacokinetics and Pharmacodynamics of CDX-0159 in Patients With Cold Contact Urticaria, Symptomatic Dermographism, or Cholinergic Urticaria

Cold Urticaria | Symptomatic Dermographism | Cholinergic Urticaria | Cold Contact Urticaria | Symptomatic Dermatographism

Germany
University of Louisville

Recruiting

Aggressive Risk-Prevention Therapies for Coronary Atherosclerotic Plaque (ART-CAP) (ARTCAP)

Coronary Artery Disease | Atherosclerosis | Heart Attack

United States
European Association of Cardiovascular Imaging

Unknown

Prognostic Impact of Myocardial Longitudinal Strain in Asymptomatic Aortic Stenosis: a Meta-Analysis

Aortic Valve Stenosis | Left Ventricular Function | Asymptomatic Conditions

France
University Hospital, Bonn

Not yet recruiting

Placebo Optimization of the Presurgical Long-term Video-EEG Monitoring (OPERA)

Symptomatic Epilepsy

Germany
Esperion Therapeutics, Inc.

Completed

Evaluation of Long-Term Efficacy of Bempedoic Acid (ETC-1002) in Patients With Hyperlipidemia at High Cardiovascular Risk (CLEAR Wisdom)

Hypercholesterolemia | Atherosclerotic Cardiovascular Disease

United States
Canadian Atherosclerosis Imaging Network
Canadian Institutes of Health Research (CIHR)

Completed

Correlation Between Coronary and Carotid Atherosclerotic Disease (CAD) and Links With Clinical Outcomes

Atherosclerosis

Canada
Assaf-Harofeh Medical Center

Completed

Carotid Atherosclerotic Disease Following Childhood Scalp Irradiation

Atherosclerosis

Israel

Clinical Trials on Symptomatic Atherosclerosis

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