Search clinical trials for: Multiple VS-105/placebo to HD subjects

Total 115 results

Vidasym, Inc.

Completed

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of VS 105

Chronic-kidney Disease Stage 5D on Stable Hemodialysis

United States
Pfizer

Completed

Study To Assess Local Tolerability of Crisaborole 2% Ointment and Vehicle Ointment In Healthy Participants Using Subject-reported Assessments and Objective Measurements

Healthy

United States
Longbio Pharma

Recruiting

A Study of Single and Multiple Doses of LP-005 in Healthy Adult Participants

Paroxysmal Nocturnal Hemoglobinuria (PNH)

China
Noema Pharma AG

Completed

A 10-week Efficacy Study of NOE-105 in Childhood Onset Fluency Disorder (Orpheus)

Childhood-Onset Fluency Disorder

United States, Australia
NP Therapeutics

Completed

Study to Assess Safety, Tolerability and Pharmacokinetics of XC7 (Which is Planned Use in the Treatment of COVID-19) in Healthy Volunteers

Covid19 | Healthy Volunteers

Russian Federation
Emerald Health Pharmaceuticals

Completed

To Evaluate the Safety and Tolerability, Pharmacokinetics, Food-effect and Pharmacodynamics of EHP-101 in Healthy Volunteers

Healthy

Australia
NEURALIS s.a.

Recruiting

Single and Multiple Intravenous Administrations of Estetrol (E4) in Healthy Adult Volunteers

Pharmacokinetics | Safety

Bulgaria
Taiwan Liposome Company

Completed

Phase IIa, Randomized, Double Blinded, Placebo Controlled, Dose Finding Study for TLC599 in OA Patients

Osteoarthritis of the Knee

Taiwan, Australia
Desentum Oy

Completed

Study to Evaluate Safety and Tolerability of sc Immunotherapy With DM-101 in Adults With Birch Pollen Allergy

Birch Pollen Allergy

Finland
PHARMENTERPRISES LLC

Completed

Double-blind, Randomized, Placebo-controlled Study of the Safety, Tolerability and Pharmacokinetics of Ascending Doses of XC243 After Single and Multiple Oral Administration in Healthy Volunteers.

Healthy Volunteers

Russian Federation
Pfizer

Completed

First Safety Study in Humans of a Single Dose of CPG 52364

Healthy Volunteers

United States
Ornovi, Inc.

Withdrawn

A First in Human Single and Multiple Ascending Dose and Open Label Food Effect Study of OR-101 in Healthy Subjects

Alopecia Areata

Australia
Hospital Regional de Alta Especialidad del Bajio
Braulio Omar Manzo Pérez; Edson Dazaeb Flores Hernández; Pompeyo Stalin Alarcón...

Unknown

Holmium Vs Trilogy Kidney Stones GUY's 1-2 (TriHolmium)

Kidney Diseases | Kidney Calculi | Kidney Stone

Mexico
SecuraBio

Completed

A Phase 2a, Efficacy and Safety Study of Duvelisib in Mild Asthmatic Subjects

Asthma

Germany, United Kingdom
YMD Eye and Face

Completed

Split-Face Prospective Study Comparing Botox to Xeomin for the Treatment of Facial Wrinkles

Facial Wrinkles

United States
Protalix

Recruiting

A Study to Evaluate the Safety, Tolerability, PK, and PD Properties of PRX-115 in Adult Volunteers With Elevated Uric Acid Levels

Gout

New Zealand
Genentech, Inc.

Completed

A Study of Vismodegib (GDC-0449, Hedgehog Pathway Inhibitor) As Maintenance Therapy in Patients With Ovarian Cancer in a Second or Third Complete Remission

Ovarian Cancer
Epygenix

Not yet recruiting

EPX-100 (Clemizole Hydrochloride) as Adjunctive Therapy in Children With Lennox Gastaut Syndrome (LGS)

Lennox Gastaut Syndrome
University of the Incarnate Word
National Eye Institute (NEI)

Completed

Impact of Color Correcting Lenses on Color Vision Deficiency

Color Vision Defects | Color Blindness | Color Blindness, Red | Color Blindness, Green

United States
AstraZeneca

Completed

A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD5718 After Single and Multiple Ascending Dose Administration to Healthy Male Subjects

Cardiovascular Disease | Healthy Male Subjects

United Kingdom
Epygenix
Forest Hills Lab; Liberyx Therapeutics

Recruiting

EPX-100 (Clemizole Hydrochloride) as Add-on Therapy to Control Convulsive Seizures in Patients With Dravet Syndrome (ARGUS)

Dravet Syndrome

United States, Canada, Spain, Georgia, Hungary
Novartis Pharmaceuticals

Completed

Canakinumab in the Treatment of Acute Gout Flares and Prevention of New Flares in Patients Unable to Use Non-steroidal Anti-inflammatory Drugs (NSAIDs) and/or Colchicines Including a 12 Week Extension and a 1 Year Open-label Extension Study. (β-RELIEVED-II)

Acute Gout

United States, Canada, Russian Federation, Netherlands, China
Novartis Pharmaceuticals

Completed

Safety and Efficacy of DNK333 in Atopic Dermatitis Patients

Pruritus in Patients With Atopic Dermatitis

Germany
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Subcutaneous Secukinumab for Moderate to Severe Chronic Plaque-type Psoriasis for up to 1 Year (ERASURE)

Moderate to Severe Plaque-type Psoriasis

United States, Colombia, Estonia, Japan, Taiwan, Israel, Canada, Lithuania, Argentina, Latvia, Iceland, Mexico
Sprout Pharmaceuticals, Inc

Terminated

12 Week Safety Trial of Flibanserin in Depressed Women Taking an SSRI or SNRI With Decreased Sexual Desire and Distress

Depression | Sexual Dysfunctions, Psychological

United States
Novartis

Completed

Efficacy and Safety of Indacaterol in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

United States, New Zealand, Belgium
Emerald Health Pharmaceuticals

Suspended

Evaluation of Safety, Tolerability and Preliminary Efficacy of EHP-101 in Diffuse Cutaneous Systemic Sclerosis

Diffuse Cutaneous Systemic Sclerosis

United States, Puerto Rico, Australia, New Zealand
University of California, San Francisco
San Francisco VA Health Care System

Completed

Pilot Human Lab Study of Lacosamide in Alcohol Use Disorder (AUD) (ACGT)

Alcohol Use Disorder

United States
Novartis Pharmaceuticals

Completed

Study of Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Inclisiran in Chinese Participants With Elevated Serum LDL-C (ORION-14)

Hyperlipidemia

China
Organon and Co

Completed

MK-0954A in Japanese Patients With Essential Hypertension Not Adequately Controlled With Losartan (MK-0954A-352)

Hypertension
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Indacaterol in Adults (40 Years and Above) With Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease (COPD)

China, Australia, India
Veralox Therapeutics

Recruiting

A Phase 2 Study of VLX-1005 Versus Placebo in Suspected Heparin Induced Thrombocytopenia

Heparin Induced Thrombocytopenia | Thrombocytopenia, Immune

United States
Dr. Kirk Brower
National Institute on Alcohol Abuse and Alcoholism (NIAAA); National Institutes...

Completed

Pharmacotherapy and Mechanisms of Sleep Disturbance in Alcohol Dependence (MA)

Alcohol Dependence | Insomnia

United States
Sung Kwang Medical Foundation

Completed

Allogenic Umbilical Cord Blood and Erythropoietin Combination Therapy for Cerebral Palsy

Cerebral Palsy

Korea, Republic of
Cingulate Therapeutics
Rho, Inc.

Completed

Phase 3 Efficacy and Safety Study in Adults With ADHD Using CTx-1301.

ADHD | Attention Deficit Hyperactivity Disorder | ADHD - Combined Type | Attention Deficit Hyperactivity Disorder Combined

United States
Amgen

Completed

Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects -2 (GAUSS-2)

Hyperlipidemia

United States, Denmark, Belgium, Germany, Hong Kong, Netherlands, France, Australia, Canada, South Africa, United Kingdom, Spain, Poland, Switzerland
Amgen

Completed

Monoclonal Antibody Against PCSK9 to Reduce Elevated LDL-C in Subjects Currently Not Receiving Drug Therapy for Easing Lipid Levels-2 (MENDEL-2)

Hyperlipidemia

United States, Denmark, Taiwan, Korea, Republic of, Australia, Belgium, Canada, South Africa, France, Turkey
Duke University

Completed

Femoral Peri-arterial Local Anesthetic Injection Decreases Tourniquet Associated Ischemic Hypertension

Total Ankle Arthroplasty | Tourniquet Hypertension | Intraoperative Hypertension | Ankle Fusion

United States
Novartis Pharmaceuticals

Completed

A Study to Assess the Efficacy and Tolerability of Diclofenac Potassium Soft Gelatin Capsules Compared With Ibuprofen Tablets in Patients With Moderate to Severe Postoperative Dental Pain

Post Operative Dental Pain

United States
Optimer Pharmaceuticals LLC

Completed

Fidaxomicin Versus Vancomycin for the Treatment of Clostridium Difficile-Associated Diarrhea (CDAD) (MK-5119-018)

Diarrhea | Clostridium Infections
Lundquist Institute for Biomedical Innovation at...
Abbott Nutrition; DaVita Dialysis

Completed

Anit-Inflammatory and Anti-Oxidative Nutrition in Dialysis Patients (AIONID)

Inflammation | Oxidative Stress | Hypoalbuminemia | Protein-energy Malnutrition | Chronic Kidney Disease (CKD) Hemodialysis

United States
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Pharmacokinetics and the Effect on Cardiac Repolarization of Odalasvir Administered as a Single Dose Tablet Under Fed Conditions in Healthy Participants

Healthy

United States
Gilead Sciences

Completed

Safety, Tolerability, Pharmacokinetics and Antiviral Activity of GS-9669 in Subjects With Chronic Hepatitis C Virus Infection

Hepatitis C

United States, Puerto Rico
Wake Forest University Health Sciences

Active, not recruiting

Study of Nasal Insulin to Fight Forgetfulness - Device Study

Cognitive Impairment | Mild Cognitive Impairment

United States
Boehringer Ingelheim

Completed

Dabigatran Etexilate for Secondary Stroke Prevention in Patients With Embolic Stroke of Undetermined Source (RE-SPECT ESUS)

Stroke | Secondary Prevention

Korea, Republic of, United States, Spain, Canada, Germany, Taiwan, Belgium, Australia, Hong Kong, India, Singapore, Thailand, Greece, Italy, Japan, China, Turkey, Russian Federation, Serbia, Switzerland, Israel, South Africa, Malaysia, Fran... and more
Swedish Orphan Biovitrum

Completed

A Study to Evaluate Efficacy and Safety of Anakinra in the Treatment of Acute Gouty Arthritis (anaGO)

Acute Gouty Arthritis

United States
Merck Sharp & Dohme LLC

Completed

Study of Telcagepant (MK-0974) in Participants With Moderate to Severe Acute Migraine With or Without Aura (MK-0974-011)

Migraine
Taichung Veterans General Hospital

Completed

L-carnitine and Coenzyme Q10 in Relation to the Oxidative Stress, Antioxidant Enzymes Activities, Inflammation, and the Risk of Coronary Artery Disease

Coronary Artery Disease

Taiwan
Amgen

Completed

Effects on Lipoprotein Metabolism From PCSK9 Inhibition Utilizing a Monoclonal Antibody (FLOREY)

Primary Hyperlipidemia and Mixed Dyslipidemia

Australia
Verona Pharma plc
Iqvia Pty Ltd; LGC Limited

Completed

Study Investigating the Effect of 4 Doses of RPL554 Given in Addition to Tiotropium to Patients With COPD

COPD

United States

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