Search clinical trials for: Oral 9-Nitrocamptothecin

Total 9019 results

Amgen

Completed

Study to Evaluate Bioavailability of Apremilast Oral Suspension Relative to Tablet and to Assess Effect of Food on the Pharmacokinetics (PK) of the Oral Suspension

Healthy Volunteers

United States
Shire

Completed

Subcutaneous Treatment With Icatibant for Acute Attacks of Hereditary Angioedema (HAE) (FAST2)

Hereditary Angioedema

Italy
Acacia Pharma Ltd

Completed

Dose-finding Study of APD403 to Prevent Nausea and Vomiting After Chemotherapy

CINV

Denmark
Marion Coe
National Institute on Drug Abuse (NIDA)

Completed

Sedative-Anxiolytic Effects on Simulated Driving Performance

Psychomotor Impairment

United States
Safaa AA Khaled

Unknown

Viral Hepatitis B and C Infection in Patients With Idiopathic Thrombocytopenic Purpura Treated With Triple Therapy

Viral Hepatitis | ITP - Immune Thrombocytopenic Purpura
Michael Cohen-Wolkowiez
The Emmes Company, LLC

Completed

Antibiotic Safety (SCAMP) (SCAMP)

Complicated Intra Abdominal Infections

United States, Canada
Boehringer Ingelheim

Completed

Efficacy and Safety Study of Meloxicam Versus Mefenamic Acid in Patients With Dysmenorrhea

Dysmenorrhea
Pulmotect, Inc.
WCCT Global

Completed

Effect of Pre-Treatment With Cromolyn or Albuterol on Response to PUL-042 Inhalation Solution (PUL-042)

Healthy

United States
Duke University
National Institute of Mental Health (NIMH)

Completed

Comparing the Effectiveness of New Versus Older Treatments for Attention Deficit Hyperactivity Disorder (The NOTA Study)

Attention Deficit Disorder With Hyperactivity

United States
Pfizer

Completed

Trial Of Irinotecan In Combination With Three Methods Of Administration Of Fluoropyrimidine.

Colorectal Neoplasms

Australia, Canada, United States, New Zealand
Chen, Catherine, M.D.
Eastern Virginia Medical School; Williams, Judith V., M.D.; Hubbard, Thomas W...

Completed

Selenium Sulfide, Ketoconazole and Ciclopirox Shampoo as Additional Treatments for Tinea Capitis (Scalp Ringworm)

Tinea Capitis

United States
Ohio State University Comprehensive Cancer Center
National Cancer Institute (NCI)

Not yet recruiting

Informing Oral Nicotine Pouch Regulations to Promote Public Health

Tobacco-Related Carcinoma

United States
Oncotherapeutics
Incyte Corporation

Not yet recruiting

Pilot Study Using Changes in Serum BCMA to Determine Disease Progression in Multiple Myeloma

Multiple Myeloma
Corey Hawes
National Center for Advancing Translational Sciences (NCATS)

Recruiting

Pediatric Oncology Nutrition Intervention Trial (POINT)

Pediatric Cancer | Nutrition Aspect of Cancer | Muscle Loss | Malnutrition, Child | Nutrition Related Cancer

United States
University of Louisville
Osteo Science Foundation

Not yet recruiting

Efficacy of Oral vs IV Antibiotics in the Treatment of Orofacial Osteomyelitis

Osteomyelitis of Jaw

United States
Zagazig University

Recruiting

Intralesional Voriconazole, or Intralesional Cryotherapy, or Oral Doxycycline in the Treatment of Cutaneous Leishmaniasis

Leishmaniasis, Cutaneous

Libyan Arab Jamahiriya
Janssen Research & Development, LLC

Recruiting

A Study of Amivantamab in Participants With Advanced or Metastatic Solid Tumors Including Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer (PALOMA-2)

Carcinoma, Non-small-Cell Lung

United States, Korea, Republic of, Italy, Israel, Malaysia, United Kingdom, China, Brazil, Spain, Germany, Japan, France
Cancer Institute and Hospital, Chinese Academy...
Beijing Huanxing Cancer Hospital

Recruiting

Safety and Efficacy of Toripalimab in HER2- Metastatic Breast Cancer Patients Treated With Metronomic Vinorelbine

Metastatic Breast Cancer

China
The Hospital for Sick Children
Children's Hospital of Philadelphia; Canadian Institutes of Health Research... and other collaborators

Recruiting

The Antibiotic Rifampin to Reduce High Levels of Blood and Urine Calcium in IIH

Idiopathic Infantile Hypercalcemia - Mild Form

Canada
Oncotherapeutics
Incyte Corporation

Recruiting

A Phase 1 Study of Ruxolitinib, Steroids and Lenalidomide for Relapsed/Refractory Multiple Myeloma (RRMM) Patients

Multiple Myeloma

United States
National Cancer Institute (NCI)

Active, not recruiting

Topotecan Hydrochloride and Carboplatin With or Without Veliparib in Treating Advanced Myeloproliferative Disorders and Acute Myeloid Leukemia or Chronic Myelomonocytic Leukemia

Acute Myeloid Leukemia | Polycythemia Vera | Essential Thrombocythemia | Myelofibrosis | Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Chronic Myelomonocytic Leukemia | Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Myelodysplastic/Myeloproliferative... and other conditions

United States
National Cancer Institute (NCI)

Active, not recruiting

Veliparib and Topotecan With or Without Carboplatin in Treating Patients With Relapsed or Refractory Acute Leukemia, High-Risk Myelodysplasia, or Aggressive Myeloproliferative Disorders

Hematopoietic and Lymphoid Cell Neoplasm | Polycythemia Vera | Essential Thrombocythemia | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Myelodysplastic Syndrome | Recurrent Adult Acute Lymphoblastic Leukemia | Secondary Myelodysplastic Syndrome | de Novo Myelodysplastic... and other conditions

United States
Stanford University
Washington University School of Medicine; Duke University; University of Washington and other collaborators

Enrolling by invitation

Antibiotic Prophylaxis in Rhinoplasty

Nasal Obstruction | Nasal Surgical Procedures

United States
Centre Hospitalier Universitaire Vaudois
Ecole Polytechnique Fédérale de Lausanne

Completed

Acute Effects of Pharmacological Neuromodulation on Leg Motor Activity in Patients With SCI Treated With EES (STIMO-PHARMA)

Drug Effect | Spinal Cord Injuries

Switzerland
Radboud University Medical Center
The PATH Malaria Vaccine Initiative (MVI)

Terminated

Safety and Efficacy of NF135 CPS Immunization (CPS135)

Malaria,Falciparum | Controlled Human Malaria Infection | Immunization; Infection

Netherlands
Arbor Pharmaceuticals, Inc.

Completed

An Efficacy and Safety Study in Children 6 to Less Than 18 Years of Age With Hypertension

Hypertension

United States, Brazil, Turkey, Poland, Mexico, Colombia, Italy, Argentina, Bulgaria, Hungary, South Africa, Ukraine
The Affiliated Nanjing Drum Tower Hospital of Nanjing...
The First Affiliated Hospital of Soochow University; The Affiliated Hospital... and other collaborators

Active, not recruiting

The Efficacy and Safety of Prostatectomy for Castration-Naive Oligometastatic Prostate Cancer

Prostatectomy | Oligometastatic Prostate Cancer | Abiraterone

China
Roswell Park Cancer Institute

Completed

Combination Chemotherapy and Donor Stem Cell Transplant in Treating Patients With Aplastic Anemia or Hematologic Cancer

Lymphoma | Unspecified Childhood Solid Tumor, Protocol Specific | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Unspecified Adult Solid Tumor, Protocol Specific | Myelodysplastic/Myeloproliferative Diseases | Nonmalignant Neoplasm

United States
Hams Hamed Abdelrahman

Completed

Glutamine With Topical Corticosteroids for Lichen Planus Treatment

Lichen Penis Planus

Egypt
Marmara University

Unknown

Turkish Validation of The Drooling Impact Scale

Cerebral Palsy | Hypersalivation

Turkey
The First Affiliated Hospital with Nanjing Medical...

Unknown

Lenalidomide, Rituximab, Gemcitabine, Oxaliplatin and Dexamethasone in Relapse and Refractory DLBCL (R2-GOD)

Diffuse Large B-cell Lymphoma Recurrent | Diffuse Large B Cell Lymphoma Refractory

China
Bayer

Completed

Epidemiological Study on the Safety of Aspirin in The Health Improvement Network (THIN) (EPISAT)

Stroke | Coronary Heart Disease | Ischemic Heart Disease | Secondary Prevention

United Kingdom
University of Sao Paulo

Unknown

Cost-efficacy of Sealing Moderate Caries Lesions in Occlusal Surfaces of Primary Molars

Dental Caries

Brazil
Fresenius Kabi

Completed

Blood Glucose Response After Oral Intake of Lactulose in Healthy Volunteers

Blood Glucose

Germany
AbbVie (prior sponsor, Abbott)
Abbott Japan Co.,Ltd

Completed

Study of Safety, Tolerability, Pharmacokinetics, and Efficacy of ABT-SLV187 in Subjects With Advanced Parkinson's Disease

Advanced Parkinson's Disease
Taipei Medical University Hospital
National Health Research Institutes, Taiwan

Completed

Treatment Strategy for Refractory Schizophrenia: Drug Interaction Between Clozapine and Fluvoxamine

Schizophrenia

Taiwan
Eastern Cooperative Oncology Group
National Cancer Institute (NCI); Southwest Oncology Group; Cancer and Leukemia...

Completed

Flutamide, Suramin, and Hydrocortisone in Treating Patients With Prostate Cancer

Prostate Cancer

United States
Shahid Beheshti University of Medical Sciences

Unknown

Oral Colchicine Combined With Intravitreal Infusion of Dexamethasone, LMW Heparin and 5-FU for Management of Proliferative Vitreoretinopathy (PVR)

Proliferative Vitreoretinopathy

Iran, Islamic Republic of
University of Washington
Washington State University

Not yet recruiting

Single-Dose Pharmacokinetics of Oral Testosterone Undecanoate With and Without Concomitant Inhibition of UGT2B17 (OralT12)

Hypogonadism, Male
Jules Bordet Institute
KU Leuven; University of Milan

Not yet recruiting

Ketorolac and Pregabalin Effects on breaSt Cancer (KePreSt) (KePreSt)

Early-stage Breast Cancer | Estrogen-receptor-positive Breast Cancer

Belgium
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Recruiting

Testing the Addition of Duvelisib or CC-486 to the Usual Treatment for Peripheral T-Cell Lymphoma

Angioimmunoblastic T-cell Lymphoma | Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma | Enteropathy-Associated T-Cell Lymphoma | Peripheral T-Cell Lymphoma, Not Otherwise Specified | Monomorphic Epitheliotropic Intestinal T-Cell Lymphoma | Follicular T-Cell Lymphoma | Nodal Peripheral T-Cell Lymphoma...

United States
Grupo Español de Linfomas y Transplante Autólogo...
Takeda

Active, not recruiting

BrEPEM-LH-22017 for Older Patients With Untreated Hodgkin Lymphoma (HL)

Hodgkin Lymphoma

Spain
Michael Hoelscher
Radboud University Medical Center; German Federal Ministry of Education and... and other collaborators

Completed

PanACEA Sutezolid Dose-finding and Combination Evaluation (SUDOCU)

Pulmonary Tuberculosis | Other Specified Pulmonary Tuberculosis

South Africa, Tanzania
Shire

Completed

Co-Administration of LDX (SPD489) and Venlafaxine XR (EFFEXOR XR) in Healthy Volunteers

Healthy

United States
University of Minnesota
National Institute of Allergy and Infectious Diseases (NIAID); Mbarara University... and other collaborators

Terminated

Cryptococcal Antigen Screening Plus Sertraline (C-ASSERT)

Cryptococcosis | AIDS-Related Opportunistic Infections | Cryptococcal Infections

Uganda
National Cancer Institute (NCI)

Completed

Tivantinib and Topotecan Hydrochloride in Treating Patients With Advanced or Metastatic Solid Tumors

Adult Solid Neoplasm

United States
University of Glasgow
GlaxoSmithKline; Chief Scientist Office of the Scottish Government; Chest, Heart...

Completed

Rosiglitazone Versus Theophylline in Asthmatic Smokers

Asthma

United Kingdom
Royal Marsden NHS Foundation Trust
Cancer Research UK; European Organisation for Research and Treatment of Cancer... and other collaborators

Unknown

International Multicentre Study in Advanced Anal Cancer Comparing Cisplatin Plus 5 FU vs Carboplatin Plus Weekly Paclitaxel (InterAACT)

Squamous Cell Carcinoma of the Anus

United States, Australia, United Kingdom
Gilead Sciences

Completed

Multicenter, Randomized, Double-Blind, Double-Dummy, Phase 3 Study of the Safety and Efficacy of Elvitegravir Versus Raltegravir

HIV Infection

Canada, Germany, United States, Spain, France, Australia, Puerto Rico, Italy, Belgium, Mexico, Switzerland, Portugal, Netherlands, United Kingdom
Fred Hutchinson Cancer Center

Completed

Treosulfan, Fludarabine Phosphate, and Total-Body Irradiation in Treating Patients With Hematological Cancer Who Are Undergoing Umbilical Cord Blood Transplant

Myelodysplastic Syndrome (MDS) | Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Acute Biphenotypic Leukemia | Acute Myeloid Leukemia in Remission | Acute Lymphoblastic Leukemia in Remission | Blasts Under 5 Percent of Bone Marrow...

United States

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