Search clinical trials for: RP-G28

Total 827 results

McGill University Health Centre/Research Institute...
Dairy Farmers of Canada

Not yet recruiting

Effect of Dairy Product Matrices on Insulin Resistance in People With Overweight and Obesity and Prediabetes

PreDiabetes | Overweight and Obesity

Canada
National Cancer Institute (NCI)

Completed

Daunorubicin Hydrochloride, Cytarabine and Oblimersen Sodium in Treating Patients With Previously Untreated Acute Myeloid Leukemia

Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult Acute Myeloid Leukemia With t(8;21)(q22;q22) | Secondary Acute Myeloid Leukemia | Untreated Adult Acute Myeloid Leukemia and other conditions

United States
University of Padova

Completed

Effect of Rocuronium on BIS Values

Breast Cancer | General Anaesthesia

Italy
National Cancer Institute (NCI)
NRG Oncology

Completed

Veliparib, Pembrolizumab, and Combination Chemotherapy in Treating Patient With Locally Advanced Rectal Cancer

Rectal Adenocarcinoma | Stage III Rectal Cancer AJCC v7 | Stage II Rectal Cancer AJCC v7

United States, Puerto Rico
IrsiCaixa
José Moltó Marhuenda, PhD, MD; Beatriz Mothe Pujadas PhD,MD; Susana Benet Garrabé... and other collaborators

Completed

A Phase I, Randomized, Double-Blind, Placebo-Controlled Safety, Tolerability and Immunogenicity Study of Candidate HIV-1 Vaccines ChAdOx1.HTI and MVA.HTI With Recombinant HIV-1 Envelope Protein ConM SOSIP.v7 gp140 Vaccine, Adjuvanted With MPLA Liposomes in ART-Suppressed HIV-1 Positive Individuals

HIV Infection

Spain
The Hospital for Sick Children
The Physicians' Services Incorporated Foundation

Unknown

Continuous Versus Cyclic Use of Oral Contraceptive Pills in Adolescents

Contraception

Canada
Radboud University Medical Center

Terminated

Cediranib as Palliative Treatment in Patients With Symptomatic Malignant Ascites or Pleural Effusion

Malignant Ascites | Malignant Pleural Effusion

Netherlands
Teva Women's Health

Completed

A Multicenter Study to Evaluate the Effects of a 91-Day Extended Cycle Oral Contraceptive on Hemostatic Parameters in Healthy Women

Oral Contraceptive | Hemostasis

United States, Italy
Gary Schwartz

Withdrawn

Neoadjuvant Run-In Study With TAK-228 Followed by Letrozole/TAK-228 in Women With High-Risk ER+/HER2- Breast Cancer

Breast Cancer

United States
Children's Hospital of Philadelphia
Penn State University; Newcastle University

Completed

Nutritional Outcomes After Vitamin A Supplementation in Subjects With SCD

Sickle Cell Anemia in Children | Vitamin A Deficiency in Children

United States
Academisch Medisch Centrum - Universiteit van Amsterdam...
Merck Sharp & Dohme LLC

Completed

Deep Neuromuscular Relaxation in Patients for Thoraco-laparoscopic Esophagectomy (DEPTH)

Esophageal Cancer | Surgery | Neuromuscular Block

Netherlands
Regional Hospital Holstebro

Completed

L-NMMA Dose-response Study in Healthy Subjects

Healthy

Denmark
Dwight Owen
Genentech, Inc.

Recruiting

Temozolomide and Atezolizumab as Second or Third Line for the Treatment of Metastatic or Recurrent Small Cell Lung Cancer

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Extensive Stage Lung Small Cell Carcinoma | Metastatic Lung Small Cell Carcinoma | Recurrent Lung Small Cell Carcinoma

United States
National Cancer Institute (NCI)

Active, not recruiting

Vorinostat and Temozolomide in Treating Patients With Malignant Gliomas

Adult Anaplastic Astrocytoma | Adult Anaplastic Oligodendroglioma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Recurrent Adult Brain Neoplasm

United States
National Cancer Institute (NCI)

Completed

Temozolomide With or Without Veliparib in Treating Patients With Relapsed or Refractory Small Cell Lung Cancer

Recurrent Small Cell Lung Carcinoma

United States
National Cancer Institute (NCI)

Completed

Oblimersen, Cytarabine, and Daunorubicin in Treating Older Patients With Acute Myeloid Leukemia

Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult Acute Myeloid Leukemia With t(8;21)(q22;q22) | Secondary Acute Myeloid Leukemia | Untreated Adult Acute Myeloid Leukemia

United States
National Cancer Institute (NCI)

Completed

Combination Chemotherapy With or Without Valspodar in Treating Patients With Previously Untreated Acute Myeloid Leukemia

Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic Leukemia With Maturation (M2) | Adult Acute Myeloblastic Leukemia Without Maturation... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Peposertib and Radiation Therapy, Followed by Temozolomide for the Treatment of Patients With Newly Diagnosed MGMT Unmethylated Glioblastoma or Gliosarcoma

Glioblastoma | Gliosarcoma

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Acalabrutinib, Umbralisib, and Ublituximab for the Treatment of Previously Untreated Mantle Cell Lymphoma

Mantle Cell Lymphoma

United States
National Cancer Institute (NCI)
Gynecologic Oncology Group

Completed

Carboplatin and Paclitaxel With or Without Bevacizumab Compared to Docetaxel, Carboplatin, and Paclitaxel in Treating Patients With Stage II, Stage III, or Stage IV Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cavity Carcinoma (Cancer)

Fallopian Tube Cancer | Ovarian Clear Cell Cystadenocarcinoma | Ovarian Endometrioid Adenocarcinoma | Ovarian Serous Cystadenocarcinoma | Stage IV Ovarian Epithelial Cancer | Primary Peritoneal Cavity Cancer | Brenner Tumor | Stage II Ovarian Epithelial Cancer | Stage III Ovarian Epithelial Cancer | Ovarian... and other conditions

United States
Northwestern University
National Cancer Institute (NCI); Merck Sharp & Dohme LLC

Terminated

Radiation Therapy With Temozolomide and Pembrolizumab in Treating Patients With Newly Diagnosed Glioblastoma

Adult Glioblastoma

United States
Stanford University

Completed

Phase 2 Sequential and Concurrent Chemoradiation for Advanced Nasopharyngeal Carcinoma (NPC)

Stage II Lymphoepithelioma of the Nasopharynx | Stage II Squamous Cell Carcinoma of the Nasopharynx | Stage III Lymphoepithelioma of the Nasopharynx | Stage III Squamous Cell Carcinoma of the Nasopharynx | Stage IV Lymphoepithelioma of the Nasopharynx | Stage IV Squamous Cell Carcinoma of the...

United States
National Cancer Institute (NCI)

Completed

Suramin and Either Docetaxel or Gemcitabine in Treating Patients With Stage IIIB or Stage IV Platinum-Refractory Non-Small Cell Lung Cancer

Stage IIIB Non-small Cell Lung Cancer | Recurrent Non-small Cell Lung Cancer | Stage IV Non-small Cell Lung Cancer

United States
The Cleveland Clinic
National Institute on Aging (NIA)

Completed

Effects of Donepezil HCL on Task-Activated fMRI Brain Activation in Healthy Older Adults at Genetic Risk for Alzheimer's Disease

Genetic Risk for Alzheimer's Disease

United States
Innocrin Pharmaceutical

Completed

A Study to Evaluate Oral VT-464 in Patients With Castration-Resistant Prostate Cancer

Castration-resistant Prostate Cancer | CRPC

United States, Greece, Switzerland, United Kingdom
Akron Children's Hospital
Cystic Fibrosis Foundation

Completed

Effect of Simvastatin on CF Airway Inflammation

Cystic Fibrosis

United States
Radboud University Medical Center
Merck Sharp & Dohme LLC

Recruiting

Impact of Deep Neuromuscular Blockade During Total Hip Replacement Surgery on Postoperative Recovery and Immune Function (HIPPO)

Quality of Life | Postoperative Complications | Neuromuscular Blockade | Innate Inflammatory Response

Netherlands
Proteostasis Therapeutics, Inc.

Completed

Study to Assess the Safety, Tolerability, PK, ECG Effects, Food Effect, and Drug-drug Interaction (DDI) of Hormonal Contraceptives of PTI-428 in Healthy Female Volunteers

Healthy Volunteer

United States
Hospices Civils de Lyon

Recruiting

Staphylococcus Aureus in Atopic Dermatitis Immunopathology (STADE)

Atopic Dermatitis

France
University of Nottingham

Unknown

Dysfunction of Nutritive Blood Flow as a Determinant of Anabolic Resistance With Age; the Role of Amino Acids in Modulating Muscle Metabolism (Ajinomoto1A)

Old Age (Focus; Not a Recognized Condition)

United Kingdom
The Lymphoma Academic Research Organisation

Recruiting

Mosunetuzumab-Lenalidomide Versus Investigator Choices in Patients With Relapsed or Refractory Marginal Zone Lymphoma

Marginal Zone Lymphoma

France
Jiangsu Province Centers for Disease Control and...
Academy of Military Medical Sciences，Academy of Military Sciences，PLA; ZHONGYIANKE... and other collaborators

Recruiting

Phase I Trial of a Recombinant COVID-19 Vaccine (CHO Cell)

COVID-19

China
Rupert Lanzenberger

Completed

Investigation of Intranasal Ketamine Related Changes in Attentional Brain Networks With Functional and Structural MRI

Ketamine Treatment

Austria
University Medical Centre Ljubljana
Medical University of Vienna; Harvard University; University of Ljubljana School...

Unknown

Laboratory Characteristics in Chronic Atrophic Acrodermatitis

Chronic Atrophic Acrodermatitis

Slovenia
Stryker Orthopaedics

Terminated

A Comparative Study of In-vivo Wear Between 28 mm and 40 mm Metal Heads (X3largeheads)

Arthroplasty, Replacement, Hip

Netherlands
Amgen

Completed

Study of Denosumab in Subjects With Giant Cell Tumor of Bone

Cancer | Giant Cell Tumor of Bone | Giant Cell Tumors | Benign Giant Cell Tumors

United States, Canada, Sweden, Poland, Germany, Netherlands, Australia, Italy, Austria, Spain, France, United Kingdom
Innocrin Pharmaceutical
Prostate Cancer Foundation; Prostate Cancer Clinical Trials Consortium

Completed

Once-daily Oral Seviteronel in Patients With Castration-Resistant Prostate Cancer Progressing on Enzalutamide or Abiraterone.

Prostate Cancer

United States
M.D. Anderson Cancer Center

Recruiting

Chemotherapy and Radiation Therapy for the Treatment of IDH Wildtype Gliomas or Non-histological (Molecular) Glioblastomas

Glioblastoma | Anaplastic Oligoastrocytoma | Oligoastrocytoma | Oligodendroglioma | Anaplastic Oligodendroglioma | WHO Grade III Glioma | Diffuse Astrocytoma, IDH-Wildtype | WHO Grade II Glioma | Anaplastic Astrocytoma, IDH-Wildtype

United States
National Cancer Institute (NCI)

Active, not recruiting

Temozolomide With or Without Veliparib in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Glioblastoma | Gliosarcoma

United States, Puerto Rico
National Cancer Institute (NCI)

Active, not recruiting

M6620 and Carboplatin With or Without Docetaxel in Treating Patients With Metastatic Castration-Resistant Prostate Cancer

Castration-Resistant Prostate Carcinoma | Metastatic Prostate Carcinoma | Stage IV Prostate Cancer AJCC v8

United States
Lawrence D Recht
Sanofi

Recruiting

Whole Brain Radiation Therapy With Standard Temozolomide Chemo-Radiotherapy and Plerixafor in Treating Patients With Glioblastoma

Glioblastoma | Malignant Glioma | Gliosarcoma | Glioblastoma With Primitive Neuronal Component | Oligodendroglial Component Present

United States
PATH
Liverpool School of Tropical Medicine; University of Rwanda; Rwanda Biomedical...

Completed

Estimating the Malaria Prevention Impact of New Nets: Observational Analyses to Evaluate the Evidence Generated During Piloted New Net Distributions in Rwanda

Malaria

Rwanda
Arjun Mittra
National Cancer Institute (NCI)

Recruiting

Intraperitoneal Oxaliplatin and Fluorouracil for the Treatment of Patients With Peritoneal Metastases From Colorectal Cancer

Metastatic Colorectal Carcinoma | Stage IV Colorectal Cancer AJCC v8 | Metastatic Malignant Neoplasm in the Peritoneum

United States
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S1505: Combination Chemotherapy or Gemcitabine Hydrochloride and Paclitaxel Albumin-Stabilized Nanoparticle Formulation Before Surgery in Treating Patients With Pancreatic Cancer That Can Be Removed by Surgery

Pancreatic Adenocarcinoma | Resectable Pancreatic Carcinoma

United States
Centocor, Inc.

Terminated

A Safety and Efficacy Study of Siltuximab (CNTO 328) in Male Subjects With Metastatic Hormone-Refractory Prostate Cancer (HRPC)

Cancer, Prostate

United States, United Kingdom, Belgium, Germany, Spain, France, Austria
Universitaire Ziekenhuizen KU Leuven
Celgene Corporation

Completed

Quality of Life in Locally Advanced or Metastatic Pancreatic Cancer Treated With Gemcitabine and Nab-paclitaxel (QOLINPAC)

Pancreatic Cancer

Belgium
Federal University of Paraíba

Completed

Evaluation of a Low Fluoride Dentifrice for Caries Control

Dental Caries

Brazil
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

NBTXR3, Chemotherapy, and Radiation Therapy for the Treatment of Esophageal Cancer

Gastroesophageal Junction Adenocarcinoma | Clinical Stage II Esophageal Adenocarcinoma AJCC v8 | Clinical Stage IIA Esophageal Adenocarcinoma AJCC v8 | Clinical Stage III Esophageal Adenocarcinoma AJCC v8 | Pathologic Stage II Esophageal Adenocarcinoma AJCC v8 | Pathologic Stage IIA Esophageal... and other conditions

United States
National Cancer Institute (NCI)

Completed

Alisertib and Combination Chemotherapy in Treating Patients With Gastrointestinal Tumors

Malignant Digestive System Neoplasm

United States
Medical University of Warsaw
Children's Memorial Health Institute, Poland

Recruiting

Prolonged Remission Induced by Phenofibrate in Children Newly Diagnosed With Type 1 Diabetes. (PRIFEN)

Diabetes Mellitus, Type 1

Poland

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