Search clinical trials for: Adaptive trial

Total 42010 results

Rocket Pharmaceuticals Inc.

Not yet recruiting

Clinical Trial to Evaluate the Efficacy of Gene Therapy for Pyruvate Kinase Deficiency

Pyruvate Kinase Deficiency

Spain, United States
Barcelona Institute for Global Health

Not yet recruiting

A Rapid Triage Test to Improve Risk-stratification of Febrile Children (EChiLiBRiST, Clinical Trial 1, Outpatients)

Infectious Disease | Child, Only | Febrile Illness
Nordlandssykehuset HF
Olympus

Not yet recruiting

Evaluating the Role of SURGical TElementoring in Acquisition of Surgical Skills of Laparoscopic Cholecystectomy. SURGTEACH Trial (SURGTEACH)

Surgical Education | Surgical Telementoring

Norway
Mayo Clinic

Not yet recruiting

NXP800 for the Treatment of Patients With Advanced or Metastatic Cholangiocarcinoma

Stage III Intrahepatic Cholangiocarcinoma AJCC v8 | Metastatic Cholangiocarcinoma | Refractory Cholangiocarcinoma | Stage III Hilar Cholangiocarcinoma AJCC v8 | Stage IV Hilar Cholangiocarcinoma AJCC v8 | Stage IV Intrahepatic Cholangiocarcinoma AJCC v8 | Advanced Cholangiocarcinoma

United States
Fundacion Rioja Salud
Universidad de Granada; Instituto de Salud Carlos III; Pharmamel S.L.

Not yet recruiting

Clinical Trial for the Evaluation of Melatonin in the Treatment of Pressure Ulcers

Pressure Ulcer
National Cheng-Kung University Hospital

Not yet recruiting

Precise Endoscopic Application of Tranexamic Acid and Sucralfate in Gastrointestinal Bleeding: A Randomized Controlled Trial

Bleed Ulcer
Regeneron Pharmaceuticals

Not yet recruiting

A Study to Test the Safety, Tolerability, and Efficacy of an Antibody, REGN7999, Injected Under the Skin for the Treatment of Iron Overload in Adult Participants With Non-Transfusion Dependent β-thalassemia, Using MRI Scans to Measure Iron Levels in the Body (FERVENT-1)

Non-transfusion Dependent Beta-thalassemia (NTDT)
Universidad de la Sabana
Universidad de Boyacá; Hospital Universitario de La Samaritana; Universidade...

Not yet recruiting

Maternal Self-efficacy and Motor Development in Premature Infants: Clinical Trial Protocol

Premature Birth | Mothers of Newborn Infants
University of Hail

Not yet recruiting

A Randomized Controlled Trial Comparing Controlled Active Motion and Early Passive Mobilization Protocols for Rehabilitation of Repaired Flexor Tendons in Zone II

Flexor Tendon Rupture

Saudi Arabia
Jinghui Wang

Recruiting

A Prospective, Single-arm, Phase II Clinical Trial to Evaluate the Efficacy and Safety of Tafolecimab and Sintilimab Combined With Chemotherapy in Patients With Advanced or Metastatic Driver Gene-negative Non-small Cell Lung Cancer After Failure of First-line Immunotherapy.

Lung Cancer

China
National Research Center for Hematology, Russia
St. Petersburg State Pavlov Medical University; Federal State Budgetary Institution...

Recruiting

IMPACT-AML: Randomized Pragmatic Clinical Trial for Relapsed or Refractory AML

Refractory Acute Myeloid Leukemia | Early Relapses of Acute Myeloid Leukemia

Russian Federation
Lan Zhu

Not yet recruiting

A Randomized Controlled Trial of Modified Ischial Spinous Fascia Fixation and Sacrospinous Ligament Fixation in the Treatment of Pelvic Organ Prolapse

Pelvic Organ Prolapse
University of Florida

Not yet recruiting

Clinical Trial to Compare Clear Aligners' Auxiliaries on Rotational Accuracy

Rotation of Tooth
89bio, Inc.

Not yet recruiting

Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH

Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis
University of Southern California
National Institute of Mental Health (NIMH)

Recruiting

Cognitive Behavioral Immersion: A Randomized Control Trial of Peer-Based Coaching in the Metaverse

Depression, Anxiety

United States
Melanoma and Skin Cancer Trials Limited

Not yet recruiting

Neoadjuvant PD-1 Inhibitor and EGFR Inhibitor in Locally Advanced Cutaneous Squamous Cell Carcinoma (NEOPECS)

Locally Advanced Cutaneous Squamous Cell Carcinoma
Beijing 302 Hospital

Not yet recruiting

Adebrelimab Plus Apatinib and Etoposide for the Treatment of HER2-Negative Breast Cancer Brain Metastasis

HER2-negative Breast Cancer Brain Metastases

China
Shanghai Changzheng Hospital

Not yet recruiting

A Clinical Trial Evaluating the Safety and Efficacy of Intravenous CD-801 in Treating Advanced HCC Patients

Advanced Hepatocellular Carcinoma
Hospital Italiano de Buenos Aires

Not yet recruiting

Mortality of MBL-producing Enterobacteriaceae Bacteremias With the Combined Use of Ceftazidime-avibactam and Aztreonam vs. Other Active Antibiotics. A Multicenter Target Trial Emulation.

Bacteremia
Second Affiliated Hospital, School of Medicine,...

Recruiting

Efficacy and Safety Trial of Using Ultra-Pulsed Shockwaves to Deliver Tranexamic Acid for the Treatment of Melasma

Chloasma

China
Aventure AB
Lund University; Carbiotix AB

Recruiting

The Effects of Fermented Brown Seaweed Intake on Glucose Metabolism and Gut Health (SEAPRO01)

Healthy Subjects

Sweden
University of Nevada, Las Vegas

Not yet recruiting

Prosthetic Performance Enhancement Trial (PROSPER)

Lower Limb Amputation Below Knee (Injury) | Lower Limb Amputation Above Knee (Injury) | Amputation | Lower Limb Amputation Knee | Lower Limb Amputation at Ankle (Injury) | Lower Limb Amputation at Hip (Injury)

United States
Assistance Publique - Hôpitaux de Paris
Institut Pasteur

Recruiting

Physiology and Pathologies Linked to Human Splenic Function : Direct and Ex-vivo Perfusion Explorations (SPLEENVIVO)

Splenectomy

France
VA Office of Research and Development

Not yet recruiting

Ketamine-assisted Integrative Treatment for Veterans With Chronic Low Back Pain and Comorbid Depression

Depression | Chronic Low Back Pain

United States
University of California, San Francisco

Not yet recruiting

Randomized Directly Observed Therapy Study to Interpret Clinical Trials of Doxy-PEP (DOT-Doxy-PEP)

Sexually Transmitted Diseases, Bacterial

United States
Leslie Ballas

Not yet recruiting

Bladder Preservation for Patients With Muscle Invasive Bladder Cancer (MIBC) With Variant Histology

Muscle-Invasive Bladder Carcinoma | Tumor

United States
Duke University
Moi University

Not yet recruiting

An Evaluation of a Family Counseling Intervention ("Tuko Pamoja") in Kenya: a Pilot Randomized Controlled Trial (C0058 (4C))

Child Abuse | Parent-Child Relations | Parenting | Child Behavior | Child Mental Disorder | Domestic Violence | Family Relations | Family Conflict | Mental Health Issue | Adolescent - Emotional Problem | Adolescent Problem Behavior | Marital Conflict

Kenya
Columbia University
National Institute on Minority Health and Health Disparities (NIMHD)

Not yet recruiting

A Single Arm Clinical Trial Assessing the Maternal Outcome Monitoring Systems" (MOMS)

Pregnancy Related Death

United States
University of Minnesota

Recruiting

Optimizing the Dose of Flucytosine for the Treatment of Cryptococcal Meningitis

Cryptococcal Meningitis

Uganda
Bayer

Not yet recruiting

A Study to Learn About Whether BAY H006689 Causes an Allergic Reaction When Applied as a Topical Gel in Healthy Participants

Pain | Healthy Volunteers

United States
Shanghai Hengrui Pharmaceutical Co., Ltd.

Not yet recruiting

A Trial of SHR-A2102 With or Without Antitumor Therapy in Advanced Solid Tumors

Advanced Solid Tumors
Gruppo Oncologico Italiano di Ricerca Clinica

Recruiting

Durvalumab With Carboplatin and Etoposide Chemotherapy in Pulmonary Large-cell Neuroendocrine Carcinoma (LCNEC) (DUPLE)

Pulmonary Large-cell Neuroendocrine Carcinoma

Italy
University of Cincinnati

Not yet recruiting

Lattice Radiotherapy for Dose-Escalated Palliation of Bulky Tumors

Cancer | Metastatic Cancer | Locally Advanced Solid Tumor | Locally Advanced | Locally Advanced Carcinoma

United States
AlaMab Therapeutics (Shanghai) Inc.

Not yet recruiting

A Study to Evaluate the Efficacy of ALMB-0168 in Solid Tumor Patients With Bone Metastatic Whose Prior Standard Treatment Have Failed

Advanced Solid Tumors With Bone Only Metastasis
Vaxxas Pty Ltd
Biomedical Advanced Research and Development Authority

Not yet recruiting

Influenza A (H7N9) Vaccine Delivered Intradermally by High-density Microarray Patch (HD-MAP) (HD-MAP)

H7N9 Influenza

Australia
Instituto Nacional de Investigacao em Saude, Angola
FUNDAÇAO CALOUSTE GULBENKIAN; FUNDACIÓN BANCARIA CAIXA D'ESTALVIS I PENSIONS... and other collaborators

Recruiting

LEARNER- Low dosE AspiRiN prEterm tRial (Angola) (LEARNER)

Pregnancy Complications | Pregnancy Related | Sickle Cell Disease | Pre-Eclampsia

Angola
Sanofi
Regeneron Pharmaceuticals

Not yet recruiting

Study in Paediatric Patients With Atopic Dermatitis Treated With Dupilumab in Spain (PROADAP)

Atopic Dermatitis
Fondazione Policlinico Universitario Agostino Gemelli...

Not yet recruiting

Minimally Invasive Simple Hysterectomy in Low Risk Cervical Cancer (LASH)

Cervical Cancer | Cervix Cancer
Ultragenyx Pharmaceutical Inc

Not yet recruiting

Long-term Extension of GTX-102 in Angelman Syndrome

Angelman Syndrome

United States, Australia, Canada, Germany, United Kingdom, Israel, France, Spain
TAO An

Recruiting

Home-based Psychoeducation for Older Adults With Frailty: A Randomised Controlled Trial

Frailty | Well-Being, Psychological

Hong Kong
TriHealth Inc.

Not yet recruiting

Histologic Comparison of Ablative Techniques for Endometriosis - a Randomized Trial

Endometriosis | Endometriosis-related Pain | Endometriosis; Peritoneum | Endometriosis Pelvic

United States
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Not yet recruiting

A Clinical Trial of TQB3117 Tablets in Patients With Advanced Malignant Cancer

Advanced Malignant Cancer

China
Lan Li

Recruiting

Effects of FMS Functional Movement Training on Body Posture Control in College Female Aerobics Athletes

Postural Balance

China
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

Clinical Trial of HR091506 Tablets in Treatment of Gout With Hyperuricemia in Adults

Gout With Hyperuricemia in Adults
Osel, Inc.
City of Hope Comprehensive Cancer Center; Miyarisan Pharmaceutical Co., Ltd.

Recruiting

Dose Finding Study of CBM588 in Combination With Nivolumab/Ipilimumab in Advanced Stage Renal Cell Carcinoma

Advanced or Metastatic Renal Cell Carcinoma

United States
Bayer

Not yet recruiting

A Study to Learn About How Much Emodepside Gets Absorbed in the Blood and How Food Affects Its Absorption When Given as a New Type of Tablet to Healthy Participants

Soil-transmitted Helminth Infection | Onchocerciasis (River Blindness)
Unilever R&D
Atlantia Food Clinical Trials

Not yet recruiting

A Randomised, Double-blind, Placebo-controlled, Crossover Study to Evaluate the Effects of a Food Ingredient on Self-reported Stress in Healthy Adults

Stress

Ireland
Eli Lilly and Company

Not yet recruiting

A Study Comparing Abemaciclib Plus Temozolomide to Temozolomide Monotherapy in Children and Young Adults With High-grade Glioma Following Radiotherapy

Glioma

United States
Brooklyn Clinical Research

Not yet recruiting

Triage Survey for Cardiovascular, Obesity, and Related Endocrine Trial Eligibility (SWIFT-CORE-101)

Cardiovascular Diseases | Obesity | Metabolic Syndrome | PreDiabetes | Diabetes Type 2

United States
Pakistan Society for Rehabilitation of Differently...
University of Karachi

Recruiting

Adaptive Response of Brain Towards Resistance Training in Healthy Individuals

Resistance Training

Pakistan

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