Search clinical trials for: low risk

Total 36339 results

Ole De Backer
Boston Scientific Corporation; Abbott; Edwards Lifesciences; Symetis SA

Active, not recruiting

Comparison of TAVR With SAVR in Younger Low Surgical Risk Patients With Severe Aortic Stenosis (NOTION-2)

Heart Diseases | Cardiovascular Diseases | Aortic Valve Stenosis | Heart Valve Diseases | Ventricular Outflow Obstruction

Finland, Norway, Sweden, Denmark, Iceland
University of Alabama at Birmingham

Active, not recruiting

Obesity Risk in African American Women is Determined by a Diet-by-phenotype Interaction

Diet Modification

United States
Assistance Publique - Hôpitaux de Paris
Fonds de Dotation ACTION

Active, not recruiting

Assessment of Flecainide to Lower the Patent Foramen Ovale Closure Risk of Atrial Arrhythmia or Tachycardia (AFLOAT)

Patent Foramen Ovale | Cryptogenic Stroke | Atrial Arrhythmia

France
Dr. Graeme Smith

Terminated

Postpartum Low-Dose Aspirin After Preeclampsia for Optimization of Cardiovascular Risk (PAPVASC) (PAPVASC)

Cardiovascular Diseases | Primary Prevention | Preeclampsia Severe

Canada
Queen's University, Belfast

Completed

A Study Examining Effects of Apples/ Apple Products on Heart Disease Risk (APPS)

Cardiovascular Disease

United Kingdom
University of Wisconsin, Madison
National Cancer Institute (NCI); University of Michigan

Completed

The Effect of Surgeon Emotional Support on Treatment Choice for Low-risk Thyroid Cancer

Thyroid Cancer | Thyroid Nodule | Benign Thyroid Nodule

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Deslorelin Combined With Low-Dose Add-Back Estradiol and Testosterone in Preventing Breast Cancer in Premenopausal Women Who Are at High Risk for This Disease

Breast Cancer | brca1 Mutation Carrier | brca2 Mutation Carrier

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Diabetes Prevention Program With or Without Hunger Training in Helping to Lower Breast Cancer Risk in Obese Participants

Obesity | Overweight | Ductal Breast Carcinoma In Situ | Deleterious BRCA1 Gene Mutation | Deleterious BRCA2 Gene Mutation | Premalignant Lesion

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Low-Dose or High-Dose Vincristine and Combination Chemotherapy in Treating Young Patients With Relapsed B-Cell Acute Lymphoblastic Leukemia

B-cell Childhood Acute Lymphoblastic Leukemia | L1 Childhood Acute Lymphoblastic Leukemia | L2 Childhood Acute Lymphoblastic Leukemia | Intermediate Risk Recurrent Childhood Acute Lymphoblastic Leukemia

United States, Canada, Australia, Switzerland
Novartis Pharmaceuticals

Completed

Study in Primary Care Evaluating Inclisiran Delivery Implementation + Enhanced Support (SPIRIT)

Atherosclerotic Cardiovascular Disease | Atherosclerotic Cardiovascular Disease Risk Equivelents | Elevated Low Density Lipoprotein Cholesterol

United Kingdom
Lawson Health Research Institute
McGill University; University of Alberta; University of Oxford; Western University... and other collaborators

Completed

Oakland-Jairath Score Validation

Lower Gastrointestinal Bleeding

Canada
Fondazione IRCCS Istituto Nazionale dei Tumori,...
University of Milano Bicocca

Active, not recruiting

AI for Lung Cancer Risk Definition in Computed Tomography Screening Programs

Lung Cancer | Blood Biomarkers

Italy
Washington University School of Medicine

Active, not recruiting

Three Fraction Accelerated Partial Breast Irradiation as the Sole Method of Radiation Therapy for Low-risk Stage 0 and I Breast Carcinoma

Breast Cancer | Breast Carcinoma

United States
UNC Lineberger Comprehensive Cancer Center

Withdrawn

PSMA-PET/MRI Low- and Intermediate-Risk Prostate Cancer

Prostate Cancer

United States
University of Pernambuco
Universidade Federal de Pernambuco

Enrolling by invitation

Effects of Different Dietary Interventions on Abdominal Fat Components and Cardiometabolic Parameters.

Cardiac Disease | Metabolic Disease | Abdominal Obesity | Cardiometabolic Syndrome

Brazil
The Hospital of Vestfold
Oslo University Hospital

Active, not recruiting

Prevention of Coronary Heart Disease in Morbidly Obese Patients (SphCor)

Hypertension | Obstructive Sleep Apnea | Morbid Obesity | Osteoarthrosis | Type 2 DM

Norway
The Hospital of Vestfold
University of Oslo; AstraZeneca

Active, not recruiting

Impact of Body Weight and Weight Loss on Drug Bioavailability, Cardiovascular Risk Factors and Metabolic Biomarkers (COCKTAIL)

Obesity

Norway
VA Office of Research and Development
Medical University of South Carolina

Completed

Vitamin D3 Supplementation for Low-Risk Prostate Cancer: A Randomized Trial (VD3PCa)

Prostate Cancer

United States
Assistance Publique Hopitaux De Marseille

Active, not recruiting

Structuring of a Lung Cancer Screening Program Including Clinical, Radiological and Biological Phenotyping Useful for the Development of Individualized Risk Prediction Tools: PREVALUNG ETOILE (PREVALUNG*)

Lung Cancer | Chronic Bronchitis | Smoking-related Pathology | Atheroma | Non-progressive Cancer > 5 Years

France
NYU Langone Health

Completed

Clinician Decision Making Regarding Surveillance for Low-risk Intraductal Papillary Mucinous Neoplasms of The Pancreas

Surgery Risk Assessment

United States
Institute of Tropical Medicine, Belgium
University Ghent; Facultad Nacional de Salud Publica

Withdrawn

Evaluation of the Effectiveness of an Intervention to Reduce Gaps in Hypertension Care in Low-income Medellin, Colombia

Hypertension

Colombia
Vanderbilt University Medical Center

Withdrawn

Penicillin Allergy Risk-Stratification and Delabeling of Low-Risk Patients

Antibiotic Allergy

United States
Sanofi

Active, not recruiting

A Phase 3 Randomized, Open-label, Multicenter Study of Isatuximab (SAR650984) in Combination With Lenalidomide and Dexamethasone Versus Lenalidomide and Dexamethasone in Patients With High-risk Smoldering Multiple Myeloma

Plasma Cell Myeloma

Italy, Korea, Republic of, Norway, Canada, Spain, Germany, Greece, Lithuania, Sweden, Israel, Hungary, France, Japan, Australia, China, Denmark, Czechia, Turkey, United States, Brazil, Ireland, New Zealand, Poland, United Kingdom
Fondazione IRCCS Istituto Nazionale dei Tumori,...
Ministry of Health, Italy; Associazione Italiana per la Ricerca sul Cancro

Completed

Early Lung Cancer Detection in High Risk Individuals (MILD)

Lung Cancer

Italy
Bristol-Myers Squibb

Active, not recruiting

Real-World Practice Patterns and Outcomes of Lower-Risk Myelodysplastic Syndrome Patients in Japan

Lower-risk Myelodysplastic Syndromes

Japan
Karl Landsteiner University of Health Sciences
Paracelsus Medical University

Completed

Medication Intake of Solid Dosage Forms: A Risk Factor for Patients With Stroke-induced Dysphagia? (MedISID)

Stroke | Dysphagia | Cerebral Infarction | Stroke, Acute

Austria
Canadian Cancer Trials Group
Canadian Institutes of Health Research (CIHR); Institute of Cancer Research... and other collaborators

Active, not recruiting

Radical Versus Simple Hysterectomy and Pelvic Node Dissection With Low-risk Early Stage Cervical Cancer (SHAPE)

Cervical Cancer

Canada, France, Austria, Germany, Belgium, United Kingdom, Netherlands, China, Ireland, Norway, Russian Federation
UNC Lineberger Comprehensive Cancer Center

Active, not recruiting

De-intensification of Radiation and Chemotherapy for Low-Risk HPV-related Oropharyngeal SCC: Follow-up Study

Head and Neck Neoplasms | Carcinoma, Squamous Cell | Oropharyngeal Neoplasms

United States
Brigham and Women's Hospital

Active, not recruiting

Extended-Duration Low-Intensity Apixaban to Prevent Recurrence in High-Risk Patients With Provoked Venous Thromboembolism (HI-PRO)

Deep Vein Thrombosis | Venous Thromboembolism | Pulmonary Embolism

United States
Mount Sinai Hospital, Canada
Sunnybrook Health Sciences Centre; University of Iowa; The Rotunda Hospital; BC... and other collaborators

Active, not recruiting

Novel Echocardiographic Methods for Early Identification of Neonates at Risk for Chronic Pulmonary Hypertension

Pulmonary Hypertension | Infant, Premature

Canada, United States, Ireland, United Kingdom
Alliance Foundation Trials, LLC.
Patient-Centered Outcomes Research Institute; M.D. Anderson Cancer Center; Washington... and other collaborators

Active, not recruiting

Comparing an Operation to Monitoring, With or Without Endocrine Therapy (COMET) Trial For Low Risk DCIS (COMET)

Ductal Carcinoma in Situ | DCIS

United States
FibroGen
AstraZeneca; Astellas Pharma Inc

Terminated

Efficacy and Safety of Roxadustat for Treatment of Anemia in Participants With Lower Risk Myelodysplastic Syndrome With Low Red Blood Cell Transfusion Burden

Primary MDS (Very Low, Low or Intermediate IPSS-R With <5% Blasts)

United States, Australia, Belgium, Germany, Israel, Italy, Korea, Republic of, Russian Federation, Spain, United Kingdom, France, Turkey, Canada, Denmark, India, Poland
Groupe Francophone des Myelodysplasies
Novartis; Neovii Biotech

Active, not recruiting

Allogeneic Hematopoietic Stem Cell Transplantation in Patients With Myelodysplastic Syndrome Low Risk

MDS

France
Hospices Civils de Lyon

Active, not recruiting

Phase 3, Multicenter, Randomized Study, Evaluating the Efficacy and Tolerability of Focused HIFU (High Intensity Focused Ultrasound) Therapy Compared to Active Surveillance in Patients With Significant Low Risk Prostate Cancer (HIFUSA)

Prostate Cancer

France
Merck Sharp & Dohme LLC

Completed

Safety and Immunogenicity of V116 in Adults With Increased Risk for Pneumococcal Disease (V116-008) (STRIDE-8)

Pneumococcal Infection

United States, Australia, Canada, Chile, Japan, Korea, Republic of, New Zealand, Poland
Canadian Cancer Trials Group

Active, not recruiting

De-Escalation Radiotherapy in Patients With Low-Risk HPV-Related Oropharyngeal Squamous Cell Carcinoma (EVADER)

Oropharyngeal Cancer

Canada
Bayer

Terminated

A Study to Learn How Well the Study Treatment Asundexian Works and How Safe it is Compared to Apixaban to Prevent Stroke or Systemic Embolism in People With Irregular and Often Rapid Heartbeat (Atrial Fibrillation), and at Risk for Stroke (OCEANIC-AF)

Atrial Fibrillation | Prevention of Stroke or Systemic Embolism

Canada, United States, Israel, Korea, Republic of, China, Taiwan, Belgium, Australia, Singapore, Malaysia, Slovakia, United Kingdom, Czechia, Latvia, Japan, Brazil, Lithuania, Germany, France, Sweden, Turkey, Switzerland, Estonia, Bul... and more
Gesellschaft fur Medizinische Innovation - Hamatologie...
ClinAssess GmbH

Completed

Safety of Lenalidomide and Markers for Disease Progression in Patients With International Prognostic Scoring System (IPSS) Low- or Intermediate-1 Risk Myelodysplastic Syndromes (MDS) With Isolated del5q (MDS-LE-MON-5)

Myelodysplastic Syndromes

Germany
GWT-TUD GmbH

Active, not recruiting

Prospective German Very High Cardiovascular Risk Patients Dyslipidemia Treatment Indication Registry (PERI-DYS)

Dyslipoproteinemias

Germany
Helsinki University Central Hospital

Active, not recruiting

a. Reducing Radioiodine Treatment in Papillary Thyroid Cancer. RAILESS

to Omit Radioiodine Treatment Safely in Patients With Low -Risk Papillary Thyroid Cancer With Seize of 11-20mm
CSSS de Gatineau

Active, not recruiting

Study of High-dose Rate (HDR) Monotherapy for Low and Intermediate Risk Prostate Cancer

Prostate Cancer

Canada
MY01 Inc.
Nova Scotia Health Authority

Completed

Clinical Trial of a New Device for Real-Time Muscle Pressure Measurements in Patients at Risk for Acute Compartment Syndrome

Compartment Syndrome Traumatic Lower Extremity | Compartment Syndrome Traumatic Upper Extremity

Canada
Dana-Farber Cancer Institute
Janssen Pharmaceuticals; The Leukemia and Lymphoma Society; Multiple Myeloma... and other collaborators

Active, not recruiting

Phase II Study of the CD38 Antibody Daratumumab in Patients With High-Risk MGUS and Low-Risk Smoldering Multiple Myeloma

Smoldering Multiple Myeloma | Monoclonal Gammopathy

United States
China National Center for Cardiovascular Diseases

Completed

Effects of Intensive Systolic Blood Pressure Lowering Treatment in Reducing RIsk of Vascular evenTs (ESPRIT) Study (ESPRIT)

Hypertension

China
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company

Completed

Treatment of High and Very High riSk Dyslipidemic pAtients for the PreveNTion of CardiOvasculaR Events (SANTORINI)

Cardiovascular Diseases | Dyslipidemia | Hypercholesterolemia | Atherosclerotic Cardiovascular Disease

Finland, Netherlands, Spain, Belgium, Sweden, Austria, United Kingdom, Switzerland, Denmark, France, Germany, Portugal, Italy, Ireland
University Hospital Olomouc
Palacky University

Completed

Comparing the Efficiency of Two Approaches in Patients at Risk of Developing Intraoperative Floppy Iris Syndrome

Cataract | Age-related Cataract | Intraoperative Floppy Iris Syndrome | Adrenergic Receptor Antagonist Adverse Reaction

Czechia
Istituto Auxologico Italiano
European Society of Hypertension; Chinese Hypertension League

Completed

Optimal Blood Pressure and Cholesterol Targets for Preventing Recurrent Stroke in Hypertensives (ESH-CHL-SHOT)

Stroke | Hypertension | Transient Ischemic Attack

Russian Federation
Oslo Metropolitan University

Enrolling by invitation

Applying Artificial Intelligence in Developing Personalized and Sustainable Healthcare for Spinal Disorders (AID-Spine)

Low Back Pain | Neck Pain | Radiculopathy | Spinal Stenosis | Disc Degeneration | Disc Herniation

Norway
Novo Nordisk A/S

Completed

A Research Study Looking at How NNC0385-0434 Tablets Work to Lower Blood Cholesterol in People With Heart Disease or a High Risk of Heart Disease

Atherosclerotic Cardiovascular Disease

Germany, Poland, United States, Netherlands, Japan, Greece, Belgium
Purdue University

Completed

Effects of Proportioning Meat and Plant-based Protein-rich Foods on Cardiovascular Disease Risk Factors (S58)

Cardiovascular Risk Factor | Healthy Diet

United States

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