Search clinical trials for: Adverse drug events geriatric risk score

Total 272232 results

Centre Hospitalier Universitaire de Nīmes

Completed

Impact of Multidisciplinary Review of Drug Prescriptions on Patient Safety in a Residence for Dependent Elderly (Rev-EHPAD)

Geriatrics | Health Services for the Aged | Residence for Dependent Elderly

France
Eli Lilly and Company

Recruiting

The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Renal Function in Adults Living With Obesity (TRIUMPH-OUTCOMES)

Overweight and Obesity

United States, Australia, Italy, Hungary, Spain, Canada, Germany, Argentina, Belgium, Czechia, Greece, Israel, Austria, Brazil, Mexico, Netherlands, Romania, India, United Kingdom, Slovakia, Poland, Turkey, Puerto Rico, France, Denmark
Centre Hospitalier Universitaire, Amiens

Recruiting

Predictive Value of Systolic Rise Time of the Plantar Arch on the Risk of Major Adverse Limb Events (MALE) and Major Adverse Cardiovascular Events (MACE) in Peripheral Artery Disease (PAD) at Critical Ischaemia Stage (TAMIS)

Peripheral Artery Disease | Critical Limb Ischemia | Major Adverse Cardiovascular Events | Major Adverse Limb Events | Hemodynamic Measure

France
University Hospital, Montpellier

Recruiting

Impact of Assessment and Management of Comorbidities in Internal Medicine on Cardiovascular Risk (COMMEDCARDIO)

Major Adverse Cardiac Events | Adverse Cardiac Event

France
Dana-Farber Cancer Institute
EMD Serono; National Comprehensive Cancer Network

Recruiting

Management of Cisplatin-Ineligible Patients With Metastatic Bladder Cancer and The Role of Geriatric Assessments

Bladder Cancer | Urothelial Carcinoma | Metastatic Bladder Cancer | Unresectable Bladder Carcinoma

United States
Currax Pharmaceuticals

Recruiting

Effect of Naltrexone Hydrochloride ER and Bupropion Hydrochloride ER Combination (Contrave®/Mysimba®) on Major Adverse Cardiovascular Events (MACE) (INFORMUS)

Obesity

United States
Chinese Academy of Medical Sciences, Fuwai Hospital

Recruiting

Intensive Lipid-lowering for Plaque and Major Adverse Cardiovascular Events in Low to Intermediate 10-year ASCVD Risk Population (ILLUMINATION)

Coronary Artery Disease Progression

China
RWTH Aachen University
B. Braun-Stiftung

Not yet recruiting

Individual Risk Profiles for Adverse Drug Reactions in Geriatric Patients

Drug-Related Side Effects and Adverse Reactions | Pharmacogenetics | Polypharmacy | Pharmacogenomic Testing
University Hospital, Bordeaux

Recruiting

Treatment Pause Versus Treatment Continuation in IMDC Good or Intermediate Risk With Only One Adverse Prognostic Factor in mRCC Patients With an Objective Response at 12 Months of Treatment With PD1/ PDL1 ICIs + VEGFR-Tyrosine Kinase Inhibitors (SPICI)

Metastatic Renal Cell Carcinoma | Good or Only One Adverse Prognostic Factor Intermediate Risk Per IMDC Score

France
Grigore T. Popa University of Medicine and Pharmacy

Not yet recruiting

The Usefulness of Assessing Heart Rate Variability in Patients With Acute Myocardial Infarction (HeaRt-V-AMI)

Myocardial Infarction | Autonomic Dysfunction

Romania
Mingzhi Zhang

Recruiting

A Prospective Clinical Study of BTK Inhibitor, PD-1 and Formustine in the First-line Treatment of Primary Central Nervous System Lymphoma

Primary Central Nervous System Lymphoma

China
Women's Hospital School Of Medicine Zhejiang University
Qilu Hospital of Shandong University; Huazhong University of Science and Technology and other collaborators

Recruiting

Combination of Methotrexate(MTX) and Actinomycin(ACTD) in the Low Risk Gestational Trophoblastic Neoplasma （GTN） Patients With Score of 5-6

Gestational Trophoblastic Tumor | Effects of Chemotherapy | Drug Toxicity

China
BioDelivery Sciences International
HealthCore, Inc.

Recruiting

Risk of Major Adverse Cardiovascular Events for Naldemedine and Other Medications for Opioid Induced Constipation in Adults With Chronic Non-Cancer Pain

Opioid-induced Constipation

United States
AbbVie

Completed

Study of Oral Venetoclax Tablets to Evaluate Adverse Events and Change in Disease Activity in Participants of Any Age With Acute Myeloid Leukemia

Acute Myeloid Leukemia (AML)

Japan
National Defense Medical Center, Taiwan

Completed

Effects of OAGB and DJB-SG on 10-year and Lifetime Risks of MACE

Obesity
Canadian Network for Observational Drug Effect...
Canadian Institutes of Health Research (CIHR); Drug Safety and Effectiveness...

Completed

Domperidone and Risk of Sudden Cardiac Death

Parkinson's Disease

Canada
University of Pennsylvania

Terminated

Incidence of Adverse Airway Events in High Risk Patients Undergoing Upper GI Endoscopy Under Anesthesia (SEDLine)

Adverse Events | SEDLine | Accoustic Respiratory Monitor RAD87 | Advanced Endoscopic Procedures

United States
Centro Cardiologico Monzino
Istituto Europeo di Oncologia

Completed

Coronary Artery Calcium and Cardiovascular Risk Factors Analysis After RT or Breast Cancer (RadioTherapy)

Breast Cancer

Italy
Esperion Therapeutics, Inc.
The Cleveland Clinic

Completed

Evaluation of Major Cardiovascular Events in Participants With, or at High Risk for, Cardiovascular Disease Who Are Statin Intolerant Treated With Bempedoic Acid (ETC-1002) or Placebo (CLEAR Outcomes)

Cardiovascular Diseases | Statin Adverse Reaction

Belgium, Germany, United States, Austria, Estonia, Mexico, New Zealand, Spain, Russian Federation, Netherlands, Hungary, Australia, Denmark, South Africa, United Kingdom, Bulgaria, Argentina, Romania, Turkey, Croatia, Serbia, Canada, Lithuan... and more
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Acupuncture for the Treatment of Intravesical BCG-Related Adverse Events in High-Risk Non-muscle Invasive Bladder Cancer

Recurrent Bladder Urothelial Carcinoma | Bladder Urothelial Carcinoma In Situ | Stage 0a Bladder Cancer AJCC v8 | Stage 0is Bladder Cancer AJCC v8 | Stage I Bladder Cancer AJCC v8 | Superficial Bladder Urothelial Carcinoma

United States
Yonsei University

Active, not recruiting

A Randomized Comparison of CLOpidogrel Monotherapy Versus Extended Dual-antiplatelet Therapy Beyond 12 Months After Implantation of Drug-eluting StEnts in High-risk Lesions or Patients; A-CLOSE Trial

Coronary Artery Disease | DES

Korea, Republic of
University of California, San Francisco
Patient-Centered Outcomes Research Institute; Kaiser Permanente

Completed

Anticoagulation Length of ThErapy and Risk of New Adverse evenTs In Venous thromboEmbolism Study (ALTERNATIVE)

Venous Thromboembolism | Anticoagulants and Bleeding Disorders

United States
Lexicon Pharmaceuticals
Sanofi

Terminated

Effect of Sotagliflozin on Cardiovascular and Renal Events in Participants With Type 2 Diabetes and Moderate Renal Impairment Who Are at Cardiovascular Risk (SCORED)

Heart Failure | Chronic Kidney Diseases | Type 2 Diabetes Mellitus

Estonia, Belgium, Sweden, Italy, China, United States, Canada, Bulgaria, Chile, Denmark, Hungary, Latvia, Mexico, Russian Federation, Serbia, Spain, Portugal, Romania, Turkey, Poland, Lithuania, Argentina, Australia, Brazil, Czechia, France, Georg... and more
Tabula Rasa HealthCare
Cambia Health Solutions

Enrolling by invitation

Simulation of Risk of Adverse Drug Events Associated With the Initiation of Drugs Repurposed for the Treatment of COVID-19 in Adults With Polypharmacy Using Data From Large Medicare and Commercially Insured Populations

COVID | Drug Effect | Adverse Drug Event | Drug Interaction

United States
Tabula Rasa HealthCare

Enrolling by invitation

Simulation of Risk of Adverse Drug Events Associated With the Initiation of Drugs Repurposed for the Treatment of COVID-19 in Frail Elderly Adults With Polypharmacy

COVID | Drug Effect | Adverse Drug Event | Drug Interaction

United States
Universitaire Ziekenhuizen KU Leuven

Completed

The Impact of a Pharmacist Intervention on Post-discharge Hypnotic Drug Discontinuation in Geriatric Inpatients

Hypnotic Withdrawal
Qian geng

Completed

Predictive Value of Cardiovascular Magnetic Resonance Related Parameters in STEMI Patients After Primary PCI for Adverse Left Ventricular Remodeling and Major Adverse Cardiovascular Events

Cardiovascular Diseases

China
Clinique Bizet

Completed

Evaluation and Comparison of Two Biomarkers (VOP and SCC) for the Prognosis of the Occurrence of Clinical Cardiovascular Events (VOP-SCC)

Cardiovascular Risk Factor

France
Methodist Health System

Completed

Effectiveness of an ADE-related Hospitalization Risk Prediction Tool for Patients (ADE-RED)

Adverse Drug Event

United States
Resverlogix Corp
PPD; ICON plc; Medidata Solutions

Completed

Effect of RVX000222 on Time to Major Adverse Cardiovascular Events in High-Risk T2DM Subjects With CAD (BETonMACE)

Coronary Artery Disease | Diabetes Mellitus, Type 2

Netherlands, Taiwan, Argentina, Israel, Poland, Russian Federation, Australia, Belgium, Serbia, Bulgaria, Hungary, Slovakia, Mexico, Croatia, Germany
University of Monastir

Completed

Prognostic Accuracy of the HEART Score in Undifferentiated Chest Pain: A Multicenter Validation Study

Coronary Disease | Risk Factor, Cardiovascular | Coronary Syndrome | Major Adverse Cardiovascular Events

Tunisia
Chinese University of Hong Kong
Prince of Wales Hospital, Shatin, Hong Kong; Food and Health Bureau, Hong Kong

Completed

Early Risk Stratification in ED Chest Pain Patients

Acute Coronary Syndrome

China
University of Florida
National Institute on Aging (NIA); US Department of Health and Human Services

Completed

Development of a Risk Prediction Screening Tool for Opioid-Prescription Injury (STOP Injury) in Older Adults Initiated on Opioids From the Emergency Department (STOP Injury)

Opioid Use

United States
Miodrag Filipovic, Prof. Dr. med.

Completed

Biomarkers, Blood Pressure, BIS: Risk Stratification/Management of Patients at Cardiac Risk in Major Noncardiac Surgery (BBB)

Heart Failure | Stroke | Postoperative Complications | Renal Insufficiency, Chronic | Death | Acute Coronary Syndrome | Acute Kidney Injury | Hypotension | Coronary Occlusion

Switzerland
Sahlgrenska University Hospital, Sweden
MetaboGen AB

Completed

Tolerability and Risk of Adverse Events With a Probiotic Supplement

Healthy Individuals

Sweden
Fox Chase Cancer Center

Completed

Dose Dense MVAC for Muscle Invasive Bladder Cancer

Muscle Invasive Bladder Cancer | High Risk Urothelial Carcinoma of the Upper Urinary Tracts

United States
Eisai Inc.
Thrombolysis In Myocardial Infarction (TIMI) Academic Research Organization

Completed

A Study to Evaluate the Effect of Long-term Treatment With BELVIQ (Lorcaserin HCl) on the Incidence of Major Adverse Cardiovascular Events and Conversion to Type 2 Diabetes Mellitus in Obese and Overweight Subjects With Cardiovascular Disease or Multiple Cardiovascular Risk Factors (CAMELLIA-TIMI)

Obesity | Cardiovascular Disease | Overweight | Type 2 Diabetes | High Cardiovascular Risk

United States, Canada, Poland, Australia, Mexico, New Zealand, Bahamas, Chile
RAND
University of California, Los Angeles; Northwestern University; University of... and other collaborators

Unknown

Reducing High-Risk Geriatric Polypharmacy Via EHR Nudges: Pilot Phase

Fall | Congestive Heart Failure | Adverse Drug Event | Chronic Kidney Failure

United States
Guangdong Provincial People's Hospital
Xiangya Hospital of Central South University; First Affiliated Hospital, Sun... and other collaborators

Unknown

Multi-omics Study of Clinical Endpoints in CHD (OmiDETCHD)

Coronary Heart Disease

China
Pfizer

Terminated

The Evaluation of Bococizumab (PF-04950615;RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects (SPIRE-1)

Cardiovascular Disease

Finland, United States, Netherlands, Spain, Korea, Republic of, China, Israel, Belgium, Germany, Australia, Czechia, Taiwan, Denmark, United Kingdom, Hungary, Poland, France, Mexico, Turkey, Canada, New Zealand, Colombia, Switzerland, Irelan... and more
National Institute of Diabetes and Digestive and...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Diabetes Prevention Program

Glucose Intolerance | Diabetes Mellitus, Non-Insulin-Dependent

United States
GlaxoSmithKline
United Biosource Corporation (UBC)

Completed

A 7-year Assessment on Subject Understanding of ZYBAN/ WELLBUTRIN Associated Risks

Depressive Disorder, Major
AHEPA University Hospital
LABNET IAE - Private Reference Diagnostic Laboratory

Unknown

Development of a Risk Prediction Algorithm Through the Investigation of Genetic Risk Factors and the Complexity of Coronary Artery Disease to Estimate Future Risk of Cardiovascular Events: Angiographic (SYNTAX Score), Clinical and Pharmacogenetic Analysis. (GESS)

Coronary Artery Disease

Greece
Genelex Corporation
University of Utah

Completed

YouScript IMPACT Registry (IMPACT)

Drug Interaction Potentiation | Adverse Drug Events | Adverse Drug Reactions | Poor Metabolizer Due to Cytochrome P450 CYP2C9 Variant | Drug Metabolism, Poor, CYP2D6-RELATED | Drug Metabolism, Poor, CYP2C19-RELATED | Cytochrome P450 Enzyme Deficiency | Cytochrome P450 CYP2D6 Enzyme Deficiency | Cytochrome... and other conditions

United States
Boehringer Ingelheim

Completed

Combined Bronchodilators in Chronic Obstructive Pulmonary Disease and the Risk of Adverse Cardio-pulmonary Events

Pulmonary Disease, Chronic Obstructive

Canada
VA Office of Research and Development

Completed

Implementation of Real-time ADE Surveillance and Decision Support (VA ADE)

Adverse Drug Events

United States
Astellas Pharma Inc

Completed

Drug Use-Results Survey of Betanis Tablets in Japan

Overactive Bladder

Japan
US Department of Veterans Affairs

Completed

Patient Profiling and Provider Feedback to Reduce Adverse Drug Events

Adverse Drug Events

United States
University of Massachusetts, Worcester
Agency for Healthcare Research and Quality (AHRQ); Baycrest Centre for Geriatric...

Withdrawn

Reducing Adverse Drug Events in the Nursing Home

Adverse Drug Events
GlaxoSmithKline

Completed

SB-480848 in Major Adverse Cardiovascular Events - Integrated Summary of Efficacy and Safety From the STABILITY Trial (LPL100601) and the SOLID-TIMI-52 Trial (SB-480848/033)

Coronary Heart Disease

Search clinical trials for: Adverse drug events geriatric risk score

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