Search clinical trials for: Bendavia™

Total 5771 results

Stealth BioTherapeutics Inc.

Completed

Study to Evaluate Safety, Tolerability, and Pharmacokinetics (PK) of Intravenous (IV) Infusion of MTP-131 (Bendavia™) in Healthy Adults

Healthy

United States
Stealth BioTherapeutics Inc.

Completed

A Phase 1 Study Investigating the Safety and Pharmacokinetics of Repeat-dose Intravenous Infusion of MTP-131 in Subjects With Impaired Renal Function

Normal and Impaired Renal Function

United States
Stealth BioTherapeutics Inc.

Completed

A Phase 2 Study to Evaluate the Impact of MTP-131 (Bendavia™) on Skeletal Muscle Function in Elderly (MOTION)

Skeletal Muscle Mitochondrial Dysfunction in the Elderly

United States
Stealth BioTherapeutics Inc.

Withdrawn

A Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of Bendavia™ (MTP-131) in Patients With Heart Failure

Heart Failure

Bulgaria
Stealth BioTherapeutics Inc.

Completed

A Study Investigating the Safety, Tolerability, and Pharmacokinetics of MTP-131 in Subjects With Congestive Heart Failure

Congestive Heart Failure

Bulgaria
Stealth BioTherapeutics Inc.

Completed

Safety, Tolerability, and Efficacy of MTP-131 for the Treatment of Mitochondrial Myopathy (MMPOWER)

Mitochondrial Myopathy

United States
Stealth BioTherapeutics Inc.
Charite University, Berlin, Germany; SCIRENT Clinical Research and Science...

Completed

A Study to Evaluate the Effects of 4 Weeks Treatment With Subcutaneous Elamipretide on Left Ventricular Function in Subjects With Stable Heart Failure With Preserved Ejection Fraction

Chronic Heart Failure

Germany, Serbia
Stealth BioTherapeutics Inc.

Completed

A Phase 1 Study Examining the Pharmacokinetics and Tolerability of a Single Oral Dose of Bendavia (MTP-131)

Healthy

United States
Stealth BioTherapeutics Inc.

Completed

Safety and Pharmacokinetic (PK) Study of Oral Bendavia Administered for 7 Days

Healthy Volunteers

United States
Cairo University

Recruiting

A Comparative Study of Visual Outcome of Two Extended Depth of Focus Intraocular Lenses After Cataract Surgery

Visual To Compare the Visual Outcome Between AcrySof™ IQ Vivity™ and TECNIS Synergy™ Intraocular Lens (Model ZFR00V )

Egypt
Stealth BioTherapeutics Inc.

Completed

A Phase 2 Study to Evaluate the Cardiac and Renal Effects of Short Term Treatment With Elamipretide in Patients Hospitalized With Congestion Due to Heart Failure

Heart Failure

Spain, Hungary, Netherlands, United Kingdom, Serbia, France, Latvia, Belgium, Bulgaria, Poland
Stealth BioTherapeutics Inc.

Completed

Safety, Tolerability, Efficacy of MTP-131 for Treatment of Mitochondrial Disease in Subjects From the MMPOWER Study (MMPOWER-2)

Primary Mitochondrial Disease

United States
King Abdulaziz University

Completed

Effect of Carriere® Motion™ Appliance on Airway Dimensions

Effect of Carriere® Motion™ Appliance on Pharyngeal Airway Dimensions | Effect of Carriere® Motion™ Appliance on Skeletal and Dental Measurements

Saudi Arabia
Stealth BioTherapeutics Inc.

Completed

An Open-Label, Phase 1 Clinical Study to Evaluate the Safety and Tolerability of Subcutaneous Elamipretide in Subjects With Intermediate Age-Related Macular Degeneration

Age-Related Macular Degeneration

United States
Stealth BioTherapeutics Inc.

Terminated

Effects of Intravenous Bendavia™ on Reperfusion Injury in Patients Undergoing Angioplasty of the Renal Artery (EVOLVE)

Renal Artery Obstruction | Ischemia Reperfusion Injury | Hypertension, Renovascular

United States
Stealth BioTherapeutics Inc.

Completed

The Impact of Intravenous Bendavia™ on Endothelial Reactivity Dysfunction in Cigarette Smoking

Healthy Volunteers

United States
Stealth BioTherapeutics Inc.

Completed

Effect of Elamipretide on Left Ventricular Function in Subjects With Stable Heart Failure With Reduced Ejection Fraction

Heart Failure

Netherlands, Italy, United Kingdom
Stealth BioTherapeutics Inc.
ICON Clinical Research

Completed

Evaluation of Myocardial Effects of MTP-131 for Reducing Reperfusion Injury in Patients With Acute Coronary Events (EMBRACE)

Reperfusion Injury | STEMI

United States, Hungary, Germany, Poland
Technical University of Munich

Completed

Covering of the Abdominal Wall in Laparotomies: Differences in Surgical Site Infections Between an Approved Abdominal 3M™ Steri-Drape™ Wound Edge Protector and Standard Woven Swabs at Technische Universität München (BaFo)

Comparing the Number of Surgical Site Infections | Covering of the Abdominal Wall in Laparotomies With an Approved Abdominal 3M™ Steri-Drape™ Wound Edge Protector and Standard Woven | Swabs

Germany
University of Texas Southwestern Medical Center

Completed

Customized Laser Ablation: Comparing Results of LADAR Vision and VISX Platforms

Customized Laser Ablation

United States
Stealth BioTherapeutics Inc.

Completed

ReCLAIM-2 Study to Evaluate Safety,Efficacy & Pharmacokinetics of Elamipretide in Subjects With AMD With Non-central GA (ReCLAIM-2)

Age-related Macular Degeneration

United States
Aubrey Inc.

Unknown

Multi-Center, Prospective, Randomized, Comparison of AWBAT™-D vs. Xeroform™ or Glucan II™ for Treatment of Donor Sites in Burn Surgery (AWBAT-D)

Treatment of Donor Site Burns

United States
UCB Biopharma S.P.R.L.

Completed

Study to Evaluate the Impact of Using Wearable Devices in Addition to Standard Clinical Practice on Parkinson´s Subject Symptoms Management

Parkinson´s Disease

United States
Columbia University

Completed

Clinical Investigation of an Eye-Tracking Device as a Predictor of Delirium in the Recovery Room After Surgery With General Anesthesia

Delirium

United States
Prince of Songkla University

Completed

Requirements of Propofol With Target Controlled Infusions for Supraglottic Airway Devices

Complication of Device Insertion | Appropriate Affect

Thailand
Cairo University

Unknown

Shade Evaluation of Monochromatic Versus Polychromatic Layering Techniques Inrestoration of Fractured Incisal Angle

Anterior Teeth
Sanofi

Completed

Immunogenicity and Safety of TETRAXIM™ Given as a Booster Dose at 4 to 6 Years of Age

Pertussis | Tetanus | Diphtheria | Poliomyelitis

Thailand
Genomind, LLC
Medpace, Inc.

Completed

Genecept Assay™ vs. Treatment-as-Usual to Evaluate Efficacy of Assay-Guided Treatment in Adults With MDD

Major Depressive Disorder

United States
Deka Research and Development
CVS Kidney Care LLC.

Completed

An Open Label Study to Allow Patients Continuous Use of the HemoCare™ Hemodialysis System

End Stage Renal Disease

United States
Sanofi Pasteur, a Sanofi Company

Completed

Study of a Live Attenuated Japanese Encephalitis Chimeric Virus Vaccine (IMOJEV™) Compared to CD.JEVAX™ in Toddlers

Japanese Encephalitis | Japanese Encephalitis Virus Disease

Korea, Republic of
Merck KGaA, Darmstadt, Germany
Merck Ltd., Taiwan; Merck Pte. Ltd., Singapore; PT Merck Tbk., Indonesia, an...

Completed

To Assess the Level of Adherence of Subjects Receiving SAIZEN® Via Easypod™ (ECOS Taiwan, Indonesia, Singapore) (ECOS TW ID SG)

Growth Disorders

Singapore, Taiwan, Indonesia
Sanofi Pasteur, a Sanofi Company

Completed

A Study of Two Doses of Oral Cholera Vaccine (Shanchol™) in Subjects Aged 1 Year and Older in the Philippines

Cholera

Philippines
Ception Therapeutics
Cephalon

Completed

Efficacy and Safety Study of Reslizumab to Treat Poorly Controlled Asthma

Asthma

United States, Canada
GlaxoSmithKline

Completed

Long-Term Follow-Up Studies at Year 6, 7, 8, 9, 10: 2 Formulations of Combined Hepatitis A/B Vaccine Compared in Subjects Aged 12-15 Years

Hepatitis B | Hepatitis A

Belgium, Czech Republic
Medtronic Neurovascular Clinical Affairs

Completed

Apollo™ Onyx™ Delivery Microcatheter Post Market Safety Study

Arteriovenous Malformations

United States
Stealth BioTherapeutics Inc.

Completed

A Study Investigating the Safety, Tolerability, and Efficacy of Elamipretide Topical Ophthalmic Solution for Treatment of Leber's Hereditary Optic Neuropathy

Leber's Hereditary Optic Neuropathy

United States
Celldex Therapeutics

Terminated

A Study of Varlilumab (Anti-CD27) and Ipilimumab and CDX-1401 in Patients With Unresectable Stage III or IV Melanoma

Unresectable Stage III or Stage IV Melanoma

United States
Advanced Bionics

Completed

Evaluation of a HiRes™ Optima Sound Processing Strategy for the HiResolution™ Bionic Ear

Severe to Profound Hearing Loss | in Adult Users of Advanced Bionics HiResolution™ Bionic Ear System

United States
Federal University of São Paulo

Completed

A Comparative Study Minisling Versus Transobturator (TOT)Sling (sui)

Female Stress Urinary Incontinence

Brazil
H. Lee Moffitt Cancer Center and Research Institute
Elucent Medical

Completed

Evaluation of EnVisio SmartClip for Intraoperative Localization of Breast Masses

Breast Cancer

United States
Astellas Gene Therapies

Completed

A Medical Chart Review of Patients With X-Linked Myotubular Myopathy (XLMTM)

Males With X-linked Myotubular Myopathy (XLMTM)

United States, United Kingdom
Portsmouth Hospitals NHS Trust
University of Portsmouth

Completed

Endorings™ Assisted Colonoscopy Versus Standard Colonoscopy for Polyp Detection (Erings™)

Intestinal Neoplasms | Digestive System Disease | Gastrointestinal Disease | Colorectal Neoplasia | Intestinal Disease | Gastrointestinal Neoplasm | Digestive Neoplasms

United Kingdom
Sanofi Pasteur, a Sanofi Company

Completed

A Study of Two Doses of Oral Cholera Vaccine (Shanchol™) in Subjects Aged 1 Year and Older in Dominican Republic

Cholera

Dominican Republic
Advanced Bionics

Completed

Benefits of the HiResolution Bionic Ear System in Adults With Asymmetric Hearing Loss

Otorhinolaryngologic Diseases | Ear Diseases | Hearing Loss | Hearing Disorders | Asymmetrical Hearing Loss | Single-Sided Deafness

United States
Centre Hospitalier Universitaire Vaudois

Unknown

FFR-CT to Detect the Absence of Hemodynamically Significant Lesions in Patients With High-risk Acute Coronary Syndrome

Acute Coronary Syndrome

Switzerland
Smith & Nephew Pte Ltd

Active, not recruiting

Safety and Efficacy of the ANTHEM™ CR Total Knee System (Anthem CR)

Non-inflammatory Degenerative Joint Disease

India, Korea, Republic of, Italy, South Africa
Sanofi Pasteur, a Sanofi Company

Completed

A Safety Study of IMOVAX Polio Vaccine in Selected Cities in China

Poliomyelitis | Polio

China
BaroNova, Inc.

Completed

A Study of the TransPyloric Shuttle™ (TPS™) for Weight Reduction in Obese Subjects

Obesity

Australia
PureIMS B.V.
Cooperative Clinical Drug Research and Development AG (CCDRD AG)

Completed

A Pilot Comparative Bioavailability Study of Levodopa Administered Via Levodopa Cyclops™ Relative to INBRIJA®

Parkinson Disease | Parkinson | Parkinson's Disease and Parkinsonism

Bulgaria
Centre Hospitalier Universitaire de Nīmes

Completed

Evaluation of Endoscopic Treatment of Zenker's Diverticulum Using LigaSure (ZENKER LS)

Zenker Diverticulum

France

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