Search clinical trials for: Prolactin Receptor (PRLR)

Total 17989 results

AbbVie

Terminated

A Study Evaluating the Safety, Pharmacokinetics and Anti-Tumor Activity of ABBV-176 in Subjects With Advanced Solid Tumors Likely to Express Prolactin Receptor (PRLR)

Advanced Solid Tumors Cancer

United States, Australia, Denmark, Spain
MedSIR
Stemline Therapeutics, Inc.

Not yet recruiting

Elacestrant + Everolimus in Patients ER+/HER2-, ESR1mut, Advanced Breast Cancer Progressing to ET and CDK4/6i. (ADELA)

Advanced Breast Cancer | ER-positive Breast Cancer | HER2-negative Breast Cancer | ESR1 Gene Mutation
Novartis Pharmaceuticals

Not yet recruiting

NEPC Study: An Exploratory Safety and Efficacy Study With PSMA, SSTR2 and GRPR Targeted Radioligand Therapy in Metastatic Neuroendocrine Prostate Cancer.

Metastatic Neuroendocrine Prostate Cancer
University of Washington
Breast Cancer Research Foundation

Not yet recruiting

Functional Imaging in Prediction of Response to Abemaciclib for Advanced Hormone Receptor-Positive, HER2-Negative Breast Cancer

Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Metastatic HER2-Negative Breast Carcinoma | Metastatic Hormone Receptor-Positive Breast Carcinoma | Locally Advanced Unresectable HER2-Negative Breast Carcinoma | Locally Advanced Unresectable Hormone Receptor-Positive...

United States
AstraZeneca

Recruiting

Phase III Study to Assess AZD9833+ CDK4/6 Inhibitor in HR+/HER2-MBC With Detectable ESR1m Before Progression (SERENA-6) (SERENA-6)

ER-Positive HER2-Negative Breast Cancer

United States, Israel, Spain, Korea, Republic of, Italy, Poland, Belgium, Norway, Bulgaria, France, Germany, United Kingdom, Japan, Taiwan, Canada, Hungary, Australia, Austria, Portugal, Turkey, Russian Federation, Slovakia, Switzer...
Carmen Clapp
Universidad Autónoma de Querétaro; Instituto Mexicano de Oftalmologia (IMO); General... and other collaborators

Recruiting

Effect of Levosulpiride on Retinal Alterations in Patients With Diabetic Retinopathy and Diabetic Macular Edema

Diabetic Retinopathy | Diabetic Macular Edema

Mexico
Rutgers, The State University of New Jersey
National Cancer Institute (NCI)

Recruiting

Androgen Receptor Antagonist ARN-509 With or Without Abiraterone Acetate, Gonadotropin-Releasing Hormone Analog, and Prednisone in Treating Patients With High-Risk Prostate Cancer Undergoing Surgery

Stage II Prostate Adenocarcinoma | Stage III Prostate Adenocarcinoma

United States
AstraZeneca

Active, not recruiting

A Comparative Study of AZD9833 Plus Palbociclib Versus Anastrozole Plus Palbociclib in Patients With ER-Positive HER2 Negative Breast Cancer Who Have Not Received Any Systemic Treatment for Advanced Disease (SERENA-4)

ER-Positive HER2-Negative Breast Cancer

Austria, Belgium, France, Germany, Italy, United Kingdom, United States, Canada, India, Taiwan, Russian Federation, Korea, Republic of, Hungary, Japan, Mexico, Turkey, China, Malaysia, Spain, Czechia, Portugal, Poland, Norway, Bulgaria, Slovaki... and more
Novartis Pharmaceuticals

Completed

Phase I Study of LFA102 in Patients With Prolactin Receptor-positive Castration-resistant Prostate Cancer or Prolactin Receptor-positive Metastatic Breast Cancer

Metastatic Breast Cancer | Castration-resistant Prostate Cancer | Uterine Leiomyoma

Spain, Belgium, Italy, United States
Cairo University

Completed

Comparative Study Between Single Versus Dual Trigger for Poor Responders in GnRH-antagonist ICSI Cycles

Assisted Reproduction

Egypt
RenJi Hospital

Unknown

Pulsatile Gonadotropin-releasing Hormone for Infertility in Non-obese Patients With Polycystic Ovary Syndrome

Polycystic Ovary Syndrome | Infertility | Ovulation Disorder

China
Seoul National University Hospital

Completed

Validation of Receptor Occupancy Simulation

Schizophrenia | Dopamine Receptor Occupancy | Medication Satisfaction | Prolactin Level

Korea, Republic of
Zhebao Wu
Peking Union Medical College Hospital; Beijing Tiantan Hospital; Chinese PLA... and other collaborators

Unknown

Dopamine D2 Receptors(D2R) Imaging in Prolactinomas

Prolactinoma
German Breast Group
Pfizer

Completed

Tamoxifen +/- GnRH Analogue vs Aromatase Inhibitor + GnRH Analogue in Male Breast Cancer Patients (MALE)

Male Breast Cancer

Germany
Oncolix, Inc.

Unknown

Study of Prolanta™ in Recurrent or Persistent Epithelial Ovarian Cancer (ProlantaOC)

Ovarian Cancer | Fallopian Tube Cancer | Peritoneal Cancer

United States
National Heart, Lung, and Blood Institute (NHLBI)

Withdrawn

Metoclopramide to Treat Anemia in Patients With Myelodysplastic Syndrome (MDS)

Myelodysplastic Syndromes

United States
Universidade Federal do Rio de Janeiro

Completed

Response to Cabergoline and Pasireotide in Non-functioning Pituitary Adenomas and Resistant Prolactinomas

Non-functioning Pituitary Adenomas | Prolactinomas

Brazil
Ferring Pharmaceuticals

Completed

Study to Assess the Efficacy and Safety of Three Dosage Strengths of Pulsatile GnRH Delivered From a Iontophoretic Patch Compared to Oral Treatment With Clomiphene or Placebo in Infertile Females

Infertility

United States
University of Oxford
National Institute for Health Research, United Kingdom

Completed

Aripiprazole and Prolactin Study (APS)

Hyperprolactinemia

United Kingdom
Novartis Pharmaceuticals

Completed

A Phase I Study of LFA102 in Japanese Patients

Castration-resistant Prostate Cancer, Advanced Breast Cancer

Japan
Pınar Özcan Cenksoy

Unknown

The Comparison of Effect of Four Different Treatment Protocols on IVF Outcomes in Poor Responders Undergoing in Vitro Fertilization.

Poor Responders Undergoing IVF
Assistance Publique - Hôpitaux de Paris
Institut Pasteur

Completed

Prolactin Receptor and Breast Diseases (Prolacsein)

Breast Cancer | Benign Breast Disease

France
Ferring Pharmaceuticals

Completed

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Three Dosage Strengths of Pulsatile GnRH

InFertility

United States
Federal University of São Paulo

Completed

Clomiphene in Males With Prolactinomas and Persistent Hypogonadism

Hypogonadotropic Hypogonadism | Prolactinoma

Brazil
Yu-Li Hospital

Unknown

The Monitor of Serum Prolactin Level in a 3 Months Aripiprazole Trial

Schizophrenia, Tardive Dyskinesia, Metabolic Syndrome

Taiwan
Aswan University

Recruiting

Systemic Versus Local Dexmedetomidine as An Adjuvant to Bupivacaine in Ultrasound Guided Erector Spinae Block

Dexmedetomidine | Erector Spinae Block

Egypt
Assiut University

Not yet recruiting

Intravenous Labetalol vs Phentolamine for the Management of Severe Preeclampsia.

Severe Pre-eclampsia
McGill University Health Centre/Research Institute...

Not yet recruiting

Alleviating Carbohydrate Counting for Patients With Type-1 Diabetes Using a Closed Loop System With Weekly Subcutaneous Semaglutide (SEMA SMA)

Diabetes Mellitus | Type 1 Diabetes

Canada
Aswan University

Recruiting

Fentanyl Versus Dexmedetomidine as an Adjuvant to Bupivacaine in Spinal Anesthesia ; Peritoneal Symptomatic Effects

Dexmedetomidine | Fentanyl

Egypt
Boston Immune Technologies and Therapeutics

Not yet recruiting

A Clinical Trial in Adults With Non-Hodgkin Lymphoma (NHL), With a Particular Emphasis on Cutaneous T Cell Lymphoma (CTCL), Testing the Safety and Activity of a Novel Drug to Inhibit a Protein Called Tumor Necrosis Factor Receptor 2 That Drives Both Lymphoma Growth and Escape of the Immune System

Peripheral T-cell Lymphoma | NHL | Cutaneous T Cell Lymphoma
M.D. Anderson Cancer Center

Not yet recruiting

Phase I/II Study of Engineered T Cell Receptor-Modified NK Cells Targeting PRAME in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapse/Refractory Myeloid Malignancies

Myeloid Malignancies | Lymphodepleting Chemotherapy

United States
The First Affiliated Hospital of Soochow University
Shanghai Unicar-Therapy Bio-medicine Technology Co.,Ltd; Suzhou Hongci Hematology...

Recruiting

Clinical Study of CAR-T Cell Therapy Following ASCT for R/R B-cell Non-Hodgkin's Lymphoma

Lymphoma, B-Cell | Autologous Stem Cell Transplantation

China
The Affiliated Nanjing Drum Tower Hospital of Nanjing...

Recruiting

The Clinical Efficacy and Safety of Finerenone in the Treatment of Primary Aldosteronism

Primary Aldosteronism | Mineralocorticoid Receptor Antagonist | Finerenone

China
Primus Pharmaceuticals
Sun Valley Arthritis Center

Recruiting

Effect of Metaxalone 640 mg (M640) on Truck Driving Ability and Cognition Compared to Other Skeletal Muscle Relaxants

Cognitive Impairment

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Adaptive Platform Trial for Personnalisation of Sepsis Treatment in Children and Adults: a Multi-national, Treatable Traits-guided, Adaptive, Bayesian Basket Trial (PALETTE)

Sepsis
Wayne State University

Not yet recruiting

Warrior CARE: Cannabis Behavioral Health (CBH)

Suicide | Post Traumatic Stress Disorder | Cannabis Use | Veterans | Marijuana

United States
Indonesia University

Not yet recruiting

Opioid Free Versus Opioid Balanced Anesthesia in Ophthalmic Surgery

Anesthesia and Analgesia | Anesthesia, Endotracheal
AstraZeneca

Not yet recruiting

Saruparib (AZD5305) Plus Camizestrant Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer (EvoPAR-BR01)

Advanced Breast Cancer

Canada
Montefiore Medical Center

Not yet recruiting

Antiemetic Fosaprepitant To Remedy Nausea and Vomiting (AFTR NV RCT)

Nausea | Vomiting | Nausea and Vomiting

United States
Changzhou No.2 People's Hospital

Not yet recruiting

An Clinical Study of NKG2D-CAR-NK Cells for the Treatment of Refractory Recurrent Multiple Myeloma

Multiple Myeloma

China
Mayo Clinic

Not yet recruiting

Stereotactic Body Radiation Therapy Plus Androgen Receptor Pathway Inhibitor and Androgen Deprivation Therapy for Treatment of Metastatic, Recurrent Hormone-Sensitive Prostate Cancer, DIVINE Trial (DIVINE)

Recurrent Prostate Cancer | Castration-resistant Prostate Cancer | Stage IVB Prostate Cancer AJCC v8 | Recurrent Castration-Sensitive Prostate Carcinoma

United States
Johns Hopkins University
National Institutes of Health (NIH)

Not yet recruiting

Behavioral Pharmacology of Orally Administered THC and D-limonene

THC | Subjective Drug Effects | D-limonene

United States
Shanghai JMT-Bio Inc.

Not yet recruiting

JMT101 in Combination With Osimertinib, Versus Cisplatin-pemetrexed in Participants With Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) Characterized by Epithermal Growth Factor Receptor (EGFR) Exon 20ins Mutations

Local Advanced or Metastatic NSCLC
University of Novi Sad

Recruiting

Intraoperative Dexmedetomidine and Coronary Artery Bypass Graft Surgery

Acute Kidney Injury

Serbia
Instituto de Investigación Biomédica de Salamanca
Spanish Clinical Research Network - SCReN; Fundación Canaria de Investigación... and other collaborators

Recruiting

Treatment of Relapsed or Refractory B-cell Lymphoma With Chimeric Antigen Receptor (CAR) T-cell Therapy Produced by a New Technology (TranspoCART19)

B-cell Lymphoma Recurrent | Refractory B-Cell Lymphoma

Spain
National Medical Research Center for Cardiology...

Recruiting

Study of Microvascular Dysfunction, CFR and Cardioprotective Effect of Early Administration of Esmolol in MI (ESMO-VASCMI)

Myocardial Infarction | Coronary Stenosis | Coronary Microvascular Dysfunction

Russian Federation
AstraZeneca

Not yet recruiting

Osimertinib With Chemotherapy as First-line Therapy for EGFR Mutation-positive NSCLC (FOREFRONT)

Neoplasms | Respiratory Tract Diseases | Lung Diseases | Neoplasms by Site | Carcinoma, Non-Small-Cell Lung | Lung Neoplasms | Respiratory Tract Neoplasms | Thoracic Neoplasms | Carcinoma, Bronchogenic | Bronchial Neoplasms

China
Catharina Ziekenhuis Eindhoven
Maastricht University

Not yet recruiting

The Contractile Response of the Thoracic Aorta to Vasoactive Substances (AorticContract)

Human Thoracic Aorta Contractility

Netherlands
Novartis Pharmaceuticals

Not yet recruiting

A Phase I Study of [177Lu]Lu-EVS459 in Patients With Ovarian and Lung Cancers

Ovarian Cancer | Lung Cancer
Ali Aminian

Not yet recruiting

Fibrosis Lessens After Metabolic Surgery (FLAMES)

Obesity | Liver Fibrosis | Non-Alcoholic Fatty Liver Disease | Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD) | Metabolic Dysfunction-Associated Steatohepatitis (MASH)

United States, Sweden, Ireland, Finland, United Kingdom, Spain, Switzerland, Brazil, Canada, Italy, Kuwait, India, Mexico

Search clinical trials for: Prolactin Receptor (PRLR)

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