Search clinical trials for: circadian rhythm,

Total 1438 results

Taipei Veterans General Hospital, Taiwan
Taipei Medical University; Ministry of Science and Technology, Taiwan

Recruiting

Effects of Chronobiology-guided Lifestyle Interventions on Insomnia Severity, Cognitive Performance, and Sleepiness

Circadian Rhythm Sleep Disorder

Taiwan
Sakarya University

Completed

The Effect of Nursing Care on Circadian Rhythm

Sleep Quality | Circadian Rhythm | Chronobiology Disorders | Nursing Care | Biological Clock Disturbance

Turkey
Electrophysiology Research Foundation

Recruiting

Treatment Of Atrial Fibrillation In Preserved Cardiac Function Heart Failure (TAP-CHF)

Heart Failure | Atrial Fibrillation | Diastolic Heart Failure

United States, Germany, Switzerland
University of Pittsburgh

Completed

Psychosocial Therapy Plus Maintenance Pharmacotherapy for Treating Bipolar Disorder

Bipolar Disorder

United States
University of Alabama at Birmingham

Completed

The Diurnal Rhythm in Natriuretic Peptide Levels

Obesity | Nocturnal Blood Pressure | Natriuretic Peptides

United States
Aix Marseille Université
University of Roma La Sapienza; WHO Collaborating Centre for Maternal and Child...

Completed

Rhythm and Music to Rehabilitate Reading Disorders (ReMus)

Reading Disability
Datascope Patient Monitoring

Completed

PREVENT - Prospective Rhythm Event Surveillance in the ER With NetGuard (PREVENT)

Cardiac Event

United States
The University of Tennessee, Knoxville
University of Tennessee Graduate School of Medicine

Recruiting

Time to Move in Pregnancy Hyperglycemia (TtM)

Hyperglycemia | Physical Activity | Glucose Intolerance | Exercise | Circadian Rhythm | GDM

United States
Medical University of Warsaw

Completed

Heart Rhythm After Intravenous Methylprednisolone Administration

Heart Failure | Hypertension | Graves Ophthalmopathy | Graves Disease | Blood Pressure | Heart Rhythm Disorder
Rhythm Pharmaceuticals, Inc.

Active, not recruiting

DAYBREAK: A Study of Setmelanotide in Patients With Specific Gene Variants in the MC4R Pathway

Genetic Obesity

United States, Spain, Netherlands, Germany, United Kingdom, Canada, Israel, Greece
Rhythm Pharmaceuticals, Inc.

Completed

Open-Label Study of Setmelanotide in Hypothalamic Obesity

Hypothalamic Obesity

United States
Rhythm Pharmaceuticals, Inc.

Completed

Phase 1b/2a Study to Evaluate Safety and Efficacy of Setmelanotide in Obese Patients

Overweight and Obesity

United States
Rhythm Pharmaceuticals, Inc.

Completed

Setmelanotide for the Treatment of Leptin Receptor (LEPR) Deficiency Obesity

Leptin Receptor Deficiency Obesity

Netherlands, Germany, United Kingdom, Canada, France, Réunion
Rhythm Pharmaceuticals, Inc.

Approved for marketing

An Expanded Access Protocol for Setmelanotide for Treatment of Bardet-Biedl Syndrome (BBS)

Obesity | Bardet-Biedl Syndrome (BBS)
Rhythm Pharmaceuticals, Inc.

Completed

Setmelanotide in a Single Patient With Partial Lipodystrophy

Obesity | Hypertriglyceridemia

United States
Rhythm Pharmaceuticals, Inc.

Completed

An Observational,Prospective Natural History Study of Early-Onset Extreme Obesity Due to Bi-Allelic Loss-of-Function Mutations in the POMC, PCSK1 or LEPR Genes (NHS)

POMC Deficiency Obesity | PCSK1 Deficiency Obesity | LEPR Deficiency Obesity

Turkey
Rhythm Pharmaceuticals, Inc.

Completed

A Phase 1 Study to Evaluate the Pharmacokinetics of Setmelanotide in Subjects With Varying Degrees of Renal Impairment

Renal Insufficiency

United States
Rhythm Pharmaceuticals, Inc.

Completed

The TEMPO (Tracing the Effect of the MC4 Pathway in Obesity) Registry

Genetic Forms of Extreme Obesity

United States, Canada
Rhythm Pharmaceuticals, Inc.

Completed

Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RM-493 Administered to Healthy, Obese, Non-diabetic Volunteers

Overweight | Obese
National Yang Ming University
Bened Biomedical Co., Ltd.

Recruiting

Efficacy Assessment of Probiotics in Improving Sleep Indices

Insomnia

Taiwan
Danish Headache Center

Completed

Circadian Rhythm and Attack-timing in Episodic Cluster Headache Patients in- and Outside of Bout: an Actigraphic Study

Cluster Headache

Denmark
Huashan Hospital

Completed

the Effects of Different Dietary Phosphorus Intake on the Circadian Pattern of Serum Phosphate in Normal Subjects

Healthy

China
American University of Beirut Medical Center

Recruiting

Exploring CBTi's Dual Effect on Sleep, Diet, & Chrononutrition

Insomnia

Lebanon
University of California, Berkeley
University of British Columbia; University College, London; Wellcome Trust; Salk... and other collaborators

Not yet recruiting

Healthy Lifestyles for Bipolar Disorder (HL)

Time Restricted Eating | Diet, Mediterranean

United States
University of Aarhus
Aarhus University Hospital

Recruiting

Cushing's Syndrome Before and After Treatment (CORRECT) (CORRECT)

Cushing Syndrome

Denmark
Uppsala University
Uppsala County Council, Sweden

Completed

Does Cognitive Behaviour Therapy (CBT) Improve the Effect of Light Therapy

Delayed Sleep Phase Syndrome

Sweden
University of Washington
National Institute of Mental Health (NIMH)

Completed

Interpersonal and Social Rhythm Therapy for Adolescents With Bipolar Disorder

Bipolar Disorder

United States
The Second Affiliated Hospital of Chongqing Medical...

Not yet recruiting

Circadian Rhythm Status and CS (Cesarean Section) Postoperative Pain

Circadian Rhythm

China
University of Erlangen-Nürnberg Medical School
Biotronik SE & Co. KG

Completed

The Circadian Rhythm of Potassium and Cystatin C (Potassium)

Sudden Cardiac Death | Cardiac Arrhythmias

Germany
University of Nottingham

Completed

Circadian Rhythm In Tobramycin Elimination In Cystic Fibrosis (CRITIC)

Cystic Fibrosis

United Kingdom
Shandong Provincial Hospital

Recruiting

The Biological Rhythm of Human Metabolite

Metabolism and Nutrition Disorder | Rhythm Nodal | Metabolism Disorder, Lipid

China
Rhythm Pharmaceuticals, Inc.

Active, not recruiting

Long Term Extension Trial of Setmelanotide

Obesity Associated With Defects in Leptin-melanocortin Pathway

United States, Netherlands, Canada, Germany, United Kingdom, France, Greece, Spain
Rhythm Pharmaceuticals, Inc.

Completed

Setmelanotide (RM-493), Melanocortin-4 Receptor (MC4R) Agonist, in Bardet-Biedl Syndrome (BBS) and Alström Syndrome (AS) Participants With Moderate to Severe Obesity

Bardet Biedl Syndrome (BBS) | Alström Syndrome (AS)

United States, United Kingdom, France, Canada, Puerto Rico, Spain
Rhythm Pharmaceuticals, Inc.

Completed

Setmelanotide in Pediatric Patients With Rare Genetic Diseases of Obesity

Bardet-Biedl Syndrome | POMC Deficiency Obesity | PCSK1 Deficiency Obesity | LEPR Deficiency Obesity

United States, Australia, Spain, United Kingdom
Rhythm Pharmaceuticals, Inc.

Completed

Setmelanotide for the Treatment of Early-Onset Pro-Opiomelanocortin (POMC) Deficiency Obesity

Pro-opiomelanocortin (POMC) Deficiency Obesity

Belgium, United States, Canada, France, Germany, Spain, United Kingdom
Rhythm Pharmaceuticals, Inc.

Completed

Setmelanotide Phase 2 Treatment Trial in Participants With Rare Genetic Disorders of Obesity

Obesity | Genetic Obesity | Obesity Due to Melanocortin 4 Receptor Deficiency

United States, United Kingdom, Germany, Netherlands, France, Canada, Greece, Israel, Spain
Leiden University Medical Center

Recruiting

Effect of Continuous Versus Cyclic Daytime Enteral Nutrition on Circadian Rhythms in Critical Illness (CIRCLES)

Critical Illness | Sleep | Enteral Nutrition | Circadian Rhythm | Intensive Care Unit

Netherlands
Kansas City Heart Rhythm Research Foundation
Kansas City Heart Rhythm Institute, Overland Park, Kansas; Texas Cardiac Arrythmia... and other collaborators

Recruiting

Left Atrial Appendage Closure With WATCHMAN FLX Device in Recurrent Gastrointestinal Bleeding: The GI-FLX Registry

Atrial Fibrillation | GI Bleeding

United States
GlaxoSmithKline

Completed

Evaluation of Fondaparinux in Patients With a Heart Rhythm Disturbance Who Undergo Restoration of Normal Heart Rhythm

Fibrillation, Atrial

France, Germany
Istanbul Bilgi University

Not yet recruiting

The Effect of Circadian Rhythm on Physical Performance in Healthy Male Individuals

Exercise | Chronotype
Brigham and Women's Hospital

Completed

Sleep Duration Required to Restore Performance During Chronic Sleep Restriction

Sleep | Sleep Deprivation | Insufficient Sleep Syndrome

United States
Westat
National Institute of Neurological Disorders and Stroke (NINDS)

Terminated

Clinical Trial of Sodium Phenylbutyrate in Children With Spinal Muscular Atrophy Type I (NPTUNE 02)

Spinal Muscular Atrophy Type I

United States
Emory University

Terminated

Rhythm Disturbances After Ventricular Septal Defects

Heart Block After Surgery

United States
University of Miami

Completed

Sleep & Postoperative Delirium in Hispanic/ Latino Patients After Cardiothoracic Surgery

Sleep Disturbance | Delirium in Old Age | Circadian Rhythm Sleep Disorder

United States
Rhythm Pharmaceuticals, Inc.

Completed

Study of Setmelanotide Effects on QTc (Corrected QT) Interval in Healthy Participants

Healthy

United States
Rhythm Pharmaceuticals, Inc.

Completed

Phase 3 Crossover Trial of Two Formulations of Setmelanotide in Patients With Specific Gene Defects in the MC4R Pathway

Bardet-Biedl Syndrome | POMC Deficiency

Netherlands, United States, Germany, Canada, Puerto Rico, United Kingdom
Rhythm Pharmaceuticals, Inc.

Completed

Phase 2 Study to Evaluate Safety and Efficacy of RM-493 in Obese Participants

Overweight

United States
Rhythm Pharmaceuticals, Inc.

Completed

Phase 2 Trial to Evaluate Safety and Efficacy of Setmelanotide (RM-493) in Obese Participants With Prader-Willi Syndrome

Prader-Willi Syndrome

United States
Rhythm Pharmaceuticals, Inc.

Completed

Genetic Testing and Phenotypic Characterization of Severely Obese Pediatric and Adult Volunteers

Pro-opiomelanocortin (POMC), Proprotein Convertase Subtilisin/Kexin Type 1 (PCSK1) and Leptin Receptor (LepR) Gene Mutations

United States, Israel, Canada, Germany, Greece, Italy, Portugal
Rhythm Diagnostic Systems

Completed

RDS MultiSense® SpO2 Validation Study

Hypoxia

United States

Search clinical trials for: circadian rhythm,

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