The Effect of Circadian Rhythm on Physical Performance in Healthy Male Individuals

The Effect of Chronotype and Circadian Rhythm on Physical Performance in Healthy Male Individuals

Little is known about optimizing the timing of exercise periods to maximize the health benefits of exercise. Furthermore, exercise is a potent modulator of skeletal muscle metabolism and it is clear that skeletal muscle has a robust circadian profile. Circadian rhythms can be observed in behavior, physiology, and metabolism. Various studies show that exercise changes the rhythm of the clock machines in skeletal muscle. Studies examining the relationship between exercise, especially strength training, and circadian rhythm are quite limited in the literature. Although some studies have shown that force peaks in the afternoon/evening hours, regardless of muscle group and contraction speed, there are no studies on how much this time interval varies from person to person and chronotype.

The aim of this study is to investigate to what extent strength training given at appropriate times for morning, evening and intermediate chronotypes creates changes in performance in healthy adult male individuals.

Study Overview

• Status: Not yet recruiting
• Conditions: Exercise; Chronotype
• Intervention / Treatment: Other: Theraband Strengthening Exercise Program

Detailed Description

After participants are informed about the research, evaluation and exercise protocol, their signed consent will be obtained.

The Morningness-Eveningness Questionnaire will be applied until 30 participants with morning type and 30 evening type chronotypes are reached. (Estimated for 100 students) After determining 30 morning type and 30 evening type participants, isokinetic evaluations will be made and vertical jump heights will be measured (T0).

Then, 15 morning type participants will be included in the morning exercise program (08:00) and 15 morning type participants will be included in the evening exercise program (18:00).

15 evening type participants will be included in the morning exercise program (08:00) and 15 evening type participants will be included in the evening exercise program (18:00).

Thus, some of the participants from both morning and evening groups will be included in strength training for 6 weeks, at a time appropriate to their chronotypes, and some at a time incompatible with their chronotypes. Isokinetic evaluations and vertical jump height measurements will be repeated at the end of the strengthening exercise program, which will last 3 days a week for 6 weeks, a total of 18 sessions.

• Study Type: Interventional
• Enrollment (Estimated): 60
• Phase: Not Applicable

Contacts and Locations

• Study Contact: Name: Furkan Cakir, MSc; Phone Number: +90 5426033944; Email: fztfurkancakir@gmail.com

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult
• Accepts Healthy Volunteers: Yes

Description

Inclusion Criteria:

• Being male,
• Between the ages of 18-30
• Having a chronotype that was morning person or evening person in the Morningness-Eveningness Questionnaire

Exclusion Criteria:

• Being female
• Having an intermediate chronotype in the Morningness-Eveningness Questionnaire
• Having a history of surgery or limitation in the knee area
• Having a metabolic, neurological, or orthopedic disorder.

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Screening
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Single

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Morning chronotype; Participants who score between 59-70 in the Morningness Eveningness Questionnaire will be assigned to the morning chronotype group.	Other: Theraband Strengthening Exercise Program; Resisted knee flexion in prone position and resisted knee extension in seated position (for dominant leg) and bilateral squats were practiced in 3 sets of 12 repetitions. Participants rested for 30 seconds between sets. The program, which lasted approximately 30 minutes in total, continued for a total of 6 weeks, the first 3 weeks with the red theraband and the last 3 weeks with the black theraband. 15 morning type participants will be included in the morning exercise program (08:00) and 15 morning type participants will be included in the evening exercise program (18:00). 15 evening type participants will be included in the morning exercise program (08:00) and 15 evening type participants will be included in the evening exercise program (18:00).
Experimental: Evening chronotype; Participants who score between 16-41 in the Morningness Eveningness Questionnaire will be assigned to the evening chronotype group.	Other: Theraband Strengthening Exercise Program; Resisted knee flexion in prone position and resisted knee extension in seated position (for dominant leg) and bilateral squats were practiced in 3 sets of 12 repetitions. Participants rested for 30 seconds between sets. The program, which lasted approximately 30 minutes in total, continued for a total of 6 weeks, the first 3 weeks with the red theraband and the last 3 weeks with the black theraband. 15 morning type participants will be included in the morning exercise program (08:00) and 15 morning type participants will be included in the evening exercise program (18:00). 15 evening type participants will be included in the morning exercise program (08:00) and 15 evening type participants will be included in the evening exercise program (18:00).

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Isokinetic strength test	Isokinetic evaluations will be made with the 'Biodex® System3 Isokinetic (Biodex Medical Systems, Inc, New York, New York, USA)' brand isokinetic dynamometer. The study will be performed on the dominant side lower extremity knee flexor and extensor muscle groups. Individuals' isokinetic quadriceps and hamstring muscle strengths will be evaluated at different angular velocities (60°/sec and 180°/sec). Quadriceps and hamstring muscle strengths will be evaluated with a protocol consisting of 5 repetitions of 60°/sec flexion-extension concentric-concentric movement, and 1 set of 10 repetitions of 180°/sec flexion-extension concentric-concentric movement. There will be 1-minute rest breaks between sets. Maximum voluntary contraction, peak torque and peak torque/body weight values will be recorded.	T0 and T1 (Baseline and after 6 week exercise program)
Vertical jump test	For vertical jump height measurement, participants were asked to stand next to the wall on the dominant foot to be evaluated (jumping leg). The participant touched the wall, which was graded in centimeters, with one hand. The participant was asked to jump with all his strength and touch the highest point he could touch. The height of the jump made by the participant with the dominant foot was measured by recording the height of the vertical tip of the hand in the starting position and the test height. This test was repeated three times, with a 60-second rest interval between each jump. The best value obtained was recorded in centimeters (cm).	T0 and T1 (Baseline and after 6 week exercise program)

Collaborators and Investigators

• Sponsor: Istanbul Bilgi University
• Investigators: Study Director: Mine Gulden Polat, PhD, Marmara University; Study Director: Ilksan Demirbuken, PhD, Marmara University, Faculty of Health Sciences; Study Director: Ender Ersin Avci, PhD, Marmara University, Faculty of Health Sciences

Study record dates

Study Major Dates

• Study Start (Estimated): April 1, 2024
• Primary Completion (Estimated): August 1, 2024
• Study Completion (Estimated): October 1, 2024

Study Registration Dates

• First Submitted: March 7, 2024
• First Submitted That Met QC Criteria: March 13, 2024
• First Posted (Actual): March 15, 2024

Study Record Updates

• Last Update Posted (Actual): March 15, 2024
• Last Update Submitted That Met QC Criteria: March 13, 2024
• Last Verified: March 1, 2024

More Information

Terms related to this study

• Keywords: physical performance; circadian rhythm; chronotype
• Other Study ID Numbers: IstanbulBUFC4

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No