Search clinical trials for: hypomethylating therapy

Total 51508 results

The First Affiliated Hospital of Soochow University

Recruiting

Maintenance Therapy of Hypomethylating Agent (HMA) in Favorable Risk Acute Myeloid Leukemia (AML) Patients

Acute Myeloid Leukemia

China
University of Florida

Not yet recruiting

Trial of Cladribine and Low-Dose Cytarabine (LoDAC) Alternating With Decitabine vs. Hypomethylating Agents (HMA) Plus Venetoclax as Frontline Therapy for AML or High-Grade MDS in Patients Unfit for Intensive Induction

Acute Myeloid Leukemia | Myelodysplastic Syndromes
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Fostamatinib for the Treatment of Lower-risk Myelodysplastic Syndromes or Chronic Myelomonocytic Leukemia Who Have Failed Therapy With Hypomethylating Agents

Refractory Chronic Myelomonocytic Leukemia | Refractory Myelodysplastic Syndrome

United States
Affiliated Hospital to Academy of Military Medical...

Recruiting

Hypomemylating Agents Combination With eDC Therapy for Elderly Patients With Myelodysplastic Syndrome (eDC-MDS)

Myelodysplastic Syndromes | Immunotherapy | Dendritic Cell | Hypomethylating Agents

China
Case Comprehensive Cancer Center

Recruiting

CPX-351 Therapy for MDS After Hypomethylating Agent Failure

Myelodysplastic Syndrome (MDS)

United States
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

Allo vs Hypomethylating/Best Supportive Care in MDS (BMTCTN1102)

MDS

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Withdrawn

CPI-613 and Hydroxychloroquine for Patients With High Risk Myelodysplastic Syndrome

Myelodysplastic Syndromes | Progressive Disease

United States
Novartis Pharmaceuticals

Completed

A Phase Ib/IIb, Open-label, Multi-center, Study of Oral Panobinostat Administered With 5-Azacitidine (in Adult Patients With Myelodysplastic Syndromes (MDS), Chronic Myelomonocytic Leukemia (CMML), or Acute Myeloid Leukemia (AML).

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Chronic Myelomonocytic Leukemia

Belgium, Hungary, Spain, Germany, Canada, Switzerland, Thailand, Korea, Republic of, United Kingdom, Italy, Austria, Sweden, France, United States
Weill Medical College of Cornell University
Sunesis Pharmaceuticals

Completed

Vosaroxin for Intermediate 2 or High-risk MDS After Failure With Hypomethylating Agent-based Therapy

Myelodysplastic Syndrome

United States
GWT-TUD GmbH

Terminated

Single Agent JNJ-56022473 in MDS and AML Patients FAILING HYPOMETHYLATING AGENT BASED THERAPY (SAMBA)

Acute Myeloid Leukemia (AML) | Myelodysplastic Syndrome (MDS)

France, Germany
Nanfang Hospital of Southern Medical University

Unknown

HMA+DLI vs DLI Preemptive Therapy Based on MRD for AL Undergoing Allo-HSCT

Minimal Residual Disease,Acute Leukemia, Hypomethylating Agents, Donor Lymphocyte Infusion, Allogeneic Hematopoietic Cell Transplantation

China
University of Utah
Genzyme, a Sanofi Company

Terminated

Low-dose Oral Clofarabine for the Treatment of IPSS INT-1, INT-2 or HIGH Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia

Cancer | Chronic Myelomonocytic Leukemia

United States
Janssen Korea, Ltd., Korea

Completed

An Observational Study for Dacogen Long-Term Treatment in Patients With Myelodysplastic Syndrome

Myelodysplastic Syndromes

Korea, Republic of
Nordic MDS Group

Completed

Evaluation of Azacitidine in Transfusion Dependent Patients With Low-risk Myelodysplastic Syndrome (MDS) or Chronic Myelomonocytic Leukemia (CMML)

Chronic Myelomonocytic Leukemia | Myelodysplastic Syndrome

Denmark, Norway, Sweden
Janssen Korea, Ltd., Korea

Completed

A Study for Dacogen Treatment in Patients With Myelodysplastic Syndrome

Myelodysplastic Syndrome
Boston Medical Group

Recruiting

Effectiveness and Safety of TENS Therapy for Premature Ejaculation (TENSPE2)

Premature Ejaculation | TEN | Sex Disorder

Mexico
Hospices Civils de Lyon

Not yet recruiting

Macrohemodynamic Impact of Fluid Removal With Net Ultrafiltration in Patients With Continuous Renal Replacement Therapy

Fluid Overload | Critically Ill | Continuous Renal Replacement Therapy | Fluid Removal

France
Dartmouth-Hitchcock Medical Center
Dartmouth College; University of Massachusetts, Worcester

Not yet recruiting

Self-administered ONe-of-a Kind Approach to Epilepsy Therapy Through a Web-based Music Application (SONATA)

Epilepsy | Refractory Epilepsy | Music

United States
Ohio State University Comprehensive Cancer Center

Not yet recruiting

A Bowel Management Program (Retrograde Rectal Enema) for the Treatment of Low Anterior Resection Syndrome in Rectal Cancer Patients

Low Anterior Resection Syndrome | Rectal Carcinoma

United States
Boston Medical Group

Recruiting

Effectiveness of Pelvic Floor Therapy for the Management of Erectile Dysfunction and Premature Ejaculation.

Erectile Dysfunction | Premature Ejaculation | Pelvic Floor; Weak | Premature (Early) Ejaculation

Colombia
Stanford University
American Heart Association

Not yet recruiting

Efficacy of Targeted Medical Therapy in Angina and Nonobstructive Coronary Arteries (MVP-ANOCA)

Angina Pectoris | Microvascular Angina | Vasospastic Angina | Myocardial Bridge of Coronary Artery

United States
Cook Children's Health Care System

Recruiting

Massage Therapy After Thoracic or Lumbar Surgery

Scoliosis; Adolescence | Adolescent Idiopathic Scoliosis, Thoracic Region | Adolescent Idiopathic Scoliosis, Lumbar Region

United States
University Hospital, Rouen

Not yet recruiting

Evaluation of the Influence of Aromatherapy and Music Therapy on Stress During the Management of Cerebral Arteriography (HERMES)

Patients Scheduled for Cerebral Arteriography for Diagnostic or Therapeutic Purposes
Fondation Hôpital Saint-Joseph

Not yet recruiting

Impact of Performing a Rapid Antibiotic Susceptibility Test on Antibiotic Therapy Adaptation in Adult Patients With Enterobacterales Bacteremia (MHR-Blood)

Bacteremia
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Not yet recruiting

Study of Avelumab and Tuvusertib in Participants With Advanced Urothelial Cancer That Has Progressed on Prior Anti-PD-(L)1 Therapy (JAVELIN DDRiver Bladder)

Urothelial Carcinoma

United States, Germany
Beijing Cancer Prevention & Treatment Society
Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Recruiting

A Prospective, Multicenter, Non-interventional, Real-world Study to Characterize Changes in Molecular Markers After Three Weeks of Targeted Therapy With Oxitinib in EGFRm NSCLC (pre-FLAME)

Non Small Cell Lung Cancer

China
Neurona Therapeutics

Not yet recruiting

Effect of NRTX-1001, a Cellular Therapy Product, for the Treatment of Refractory Bilateral TLE

Epilepsy, Temporal Lobe
Fudan University

Not yet recruiting

Fruquintinib Plus Camrelizumab and HAIC in the Treatment of Non-MSI-H Advanced Colorectal Cancer

Colorectal Cancer

China
Shanghai Zhongshan Hospital

Not yet recruiting

PD-1/PD-L1 Inhibitors and Anti-angiogenic Therapy Combined With/Without TACE/HAIC in Patients With BCLC B/C Hepatocellular Carcinoma Beyond Up-to-7

Hepatocellular Carcinoma
Adai Technology (Beijing) Co., Ltd.

Recruiting

Digital Cognitive Behavioral Therapy for Depressive Disorders

Depression | Anxiety

China
Gaffree & Guinle Universitary Hospital
Rio de Janeiro State Research Supporting Foundation (FAPERJ)

Recruiting

Efficacy of Photobiomodulation in the Rehabilitation of Olfactory Dysfunctions Induced by Long COVID-19

COVID-19 | Rehabilitation | Anosmia | Laser Therapy | Ageusia

Brazil
Ibn Haldun University

Not yet recruiting

The Effectiveness of Transdiagnostic CBT Protocol on Anxiety Disorders

Anxiety Disorders | Generalized Anxiety Disorder | Social Anxiety Disorder | Panic Disorder | Anxiety Disorder NOS

Turkey
AstraZeneca
Premier HealthCare Solutions Inc.

Recruiting

Combination Short-Acting BroNchodilator and Inhaled Corticosteroid Rescue Therapy on Health Outcomes in Routine Care (ANCHOR)

Asthma

United States
Claudia Aristizábal
Sanitas University

Not yet recruiting

Music Therapy Songwriting and Mental Health in Neonatel Intensive Care Unit (NICU) Parents

Mental Health Impairment

Colombia, Poland
Çankırı Karatekin University

Recruiting

Comparison of Maternal Role Preparation and Awareness-Centred Occupational Therapy Trainings in Pregnant Women

Pregnancy Related | Postpartum Complication

Turkey
University of Southern California
National Cancer Institute (NCI)

Not yet recruiting

Access to Genetic Testing in Underserved Patients With Cancer

Malignant Solid Neoplasm | Breast Carcinoma | Metastatic Prostate Carcinoma | Ovarian Carcinoma | Triple-Negative Breast Carcinoma | Male Breast Carcinoma | Pancreatic Exocrine Neoplasm | Stage IVB Prostate Cancer American Joint Committee on Cancer v8

United States
Universidad Católica San Antonio de Murcia

Not yet recruiting

Upper Limb Blood Flow Restriction in Handball Players

Sports Physical Therapy

Spain
Takeda

Recruiting

A Study Evaluating Soticlestat in Participants With Dravet Syndrome or Lennox-Gastaut Syndrome Who Have Been Exposed to Fenfluramine

Dravet Syndrome (DS) | Lennox-Gastaut Syndrome (LGS)

United Kingdom, Denmark
Universidad Católica San Antonio de Murcia

Not yet recruiting

Plyometric and Stability Exercise Protocol in Female Basketball Players

Sports Physical Therapy

Spain
Rocket Pharmaceuticals Inc.

Not yet recruiting

Clinical Trial to Evaluate the Efficacy of Gene Therapy for Pyruvate Kinase Deficiency

Pyruvate Kinase Deficiency

Spain, United States
NeuFit - Neurological Fitness and Education

Recruiting

Impact of Direct Current Electrical Stimulation on Treatment of Lumbosacral Radiculopathy

Radiculopathy Lumbar | Radiculopathy Sacral | Radiculopathy Multiple Sites

United States
Chen Xiaoping

Not yet recruiting

Neoadjuvant Therapy in Patients With Resectable HCC Screened by a Multimodal Deep Learning Model

HCC
McGill University

Recruiting

Accuracy of a Continuous Ketone Monitoring (CKM) System in Individuals With Type 1 Diabetes on Insulin Pump Therapy. (CKM 1)

type1diabetes

Canada
First Affiliated Hospital of Fujian Medical University

Not yet recruiting

FAPI and FDG PET/MRI in Diagnosis and Therapy Prediction of Bladder Cancer

Urinary Bladder Neoplasms
Cancer Institute and Hospital, Chinese Academy...

Recruiting

Induction Chemoimmunotherapy Combined With Chemoradiotherapy in Esophageal Cancer

Esophageal Cancer | Surgery | Immunotherapy | Chemoradiotherapy | Induction Therapy

China
Sun Yat-sen University

Recruiting

Prebiotics and the Management of Hyperuricemia

Subjects With Hyperuricemia

China
Peking University Third Hospital
Biotech Pharmaceutical Co., Ltd.

Not yet recruiting

SBRT Combined With Nimotuzumab and Mono-chemotherapy in Locally Advanced Pancreatic Cancer (Nim-PC-28)

Advanced Pancreatic Cancer
The Christie NHS Foundation Trust
Royal Marsden NHS Foundation Trust; University College London Hospitals

Not yet recruiting

Investigating the Role of Adjuvant Proton Beam Therapy in Patients With Parotid Carcinoma (PRONTO)

Parotid Cancer
Bristol-Myers Squibb

Recruiting

Observational Study in Japanese Patients With Peripheral T-Cell Lymphoma Who Received Second-Line Therapy

Peripheral T-cell Lymphoma

Japan
GeneCradle Inc

Recruiting

Evaluation of Safety and Efficacy of Gene Therapy Drug in the Treatment of Spinal Muscular Atrophy (SMA) Type 3 Patients

Spinal Muscular Atrophy Type 3

China

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