Search clinical trials for: substrate metabolism

Total 27531 results

Chiesi Farmaceutici S.p.A.

Recruiting

Effect of Erythromycin on the Absorption, Metabolism and Elimination of CHF6001 in Healthy Volunteers

Chronic Obstructive Pulmonary Disease

Bulgaria
University of Aarhus
Aarhus University Hospital

Recruiting

CIRcadian Rhythms and CortisoL. Effects on Substrate Metabolism and Clock Gene Expression and Functioning (CIRCLE)

Healthy

Denmark
Maastricht University Medical Center

Recruiting

Timing Exercise Training as Strategy to Improve Insulin Sensitivity and Substrate Metabolism in Men and Woman With Pre-diabetes (Timed Training)

Overweight and Obesity | Pre-diabetes

Netherlands
University of British Columbia
University of Otago

Not yet recruiting

Brain Substrate Switch to Ketones and Lactate (BSS)

Metabolic Diseases | Aging Problems

Canada
Heinrich-Heine University, Duesseldorf

Recruiting

Mitochondrial Substrate Utilization in the Diabetic Human Heart

Heart Failure | Mitochondrial Diseases | Insulin Resistance | Diabetic Cardiomyopathies | Type2diabetes

Germany
Kirsten Bell
McMaster University

Recruiting

Sex Differences in Metabolism Following a High-fat Meal (HFM)

Healthy Nutrition

Canada
Karolinska University Hospital
Karolinska Institutet

Recruiting

A Longitudinal Investigation of Energy Expenditure and Substrate Utilization in Critically Ill Patients (EPIC)

Critical Illness

Australia, Switzerland, Sweden, Netherlands
Université de Sherbrooke
Maastricht University Medical Center; McMaster University; University of Calgary and other collaborators

Recruiting

Restoring 24-hour Substrate Rhythmicity to Improve Glycemic Control by Timing of Lifestyle Factors (TIMED)

Prediabetic State

Canada
Touro University, California

Recruiting

Fructose: Substrate, Stimulus, or Both?

Insulin Resistance | Insulin Sensitivity | Pre Diabetes

United States
Cambridge University Hospitals NHS Foundation Trust
Medical Research Council; National Institute for Health Research, United Kingdom

Recruiting

Gaucherite - A Study to Stratify Gaucher Disease (Gaucherite)

Gaucher Disease, Type III | Gaucher Disease, Type I

United Kingdom
University of Bath

Completed

Body Composition and Lipid Metabolism at Rest and During Exercise: A Cross-Sectional Analysis.

Exercise | Lipid Metabolism | Substrate Metabolism

United Kingdom
Shire

Terminated

A Study of VPRIV in Participants With Gaucher Disease Previously Treated With Other Enzyme Replacement Therapies or Substrate Reduction Therapies

Gaucher Disease

Canada
University of Pennsylvania

Active, not recruiting

Nicotinic Hepatic Metabolism on Neuroreceptor Substrates of Nicotine Addiction

Smoking, Tobacco

United States
Rivus Pharmaceuticals, Inc.

Withdrawn

Ph 2a Study of HU6 on Energy Metabolism, Muscle and Liver Substrate Metabolism, and Mitochondrial Function in Subjects Who Are Overweight or Obese With Type 2 Diabetes

Obesity | Diabete Type 2

United States
Takeda

Completed

A Study of Enzyme Replacement Therapy (VPRIV) in People With Type 1 Gaucher Disease Who Were Previously Treated With Substrate Reduction Therapy (SWITCH)

Gaucher Disease

United States
University of Vienna
Medical University of Vienna

Completed

Glycaemic Index and Substrate Metabolism (GI)

Substrate Metabolism During Exercise

Austria
Bristol-Myers Squibb

Completed

A Study to Assess the Effect of BMS-986419 on the Single Dose Drug Levels of Probe Substrates in Healthy Participants

Healthy Volunteers

United States
Alexion

Completed

Study of ALXN1840 on the Metabolism of a CYP2B6 Substrate in Healthy Participants

Wilson Disease

United States
Alexion

Completed

Phase 1 Study of ALXN1840 on the Metabolism of a CYP2C9 Substrate in Healthy Participants.

Wilson Disease

United States
University of Liverpool
Metabolic Health Solutions UK

Completed

Energy Expenditure From ECAL Indirect Calorimeter in a Multicomponent Weight Management Service (ECAL)

Obesity | Severe Obesity | Sleep Apnoea

United Kingdom
University of Aarhus

Active, not recruiting

Effects of Intermittent Fasting on Insulin Resistance, Cardiac Metabolism, and Cerebral Perfusion

Obesity | Insulin Resistance

Denmark
University of Illinois at Chicago
Oregon State University

Completed

Licorice Botanical Dietary Supplements - Metabolism and Safety in Women

Food-drug Interaction

United States
University Hospital, Ghent
Pfizer

Completed

Growth Hormone, IGF-1 and Medical Treatment in Acromegaly: Are There Effects on Gut Hormone Physiology and Postprandial Substrate Metabolism?

Acromegaly

Belgium
Emalex Biosciences Inc.
ICON Early Phase Services; Nuventra

Completed

Drug-Drug Interaction Study to Evaluate the Effects of Ecopipam on the Pharmacokinetics of Multiple Substrates for Drug Metabolism and Transport

Drug Interaction

United States
Rigshospitalet, Denmark

Completed

Meal-regulated Substrate Metabolism, Influence of Obesity and IL-6

Healthy | Obesity

Denmark
United States Army Research Institute of Environmental...

Active, not recruiting

Ketone Supplements and Substrate Oxidation and Physical Performance

Ketosis | Glucose Metabolism

United States
Southern Illinois University Edwardsville

Terminated

Effects of Resistance Training on Substrate Metabolism During the Menstrual Cycle

Menstrual Cycle | Substrate Metabolism

United States
Maastricht University
AstraZeneca

Completed

Effects of 2 Weeks Treatment With Dapagliflozin in Subjects With an Impaired Glucose Homeostasis on Nocturnal Substrate Oxidation (MaasFlex)

Prediabetic State | Substrate Oxidation

Netherlands
University of Primorska

Completed

Helichrysum Italicum Infusion Ingestion in Humans (SMILJ)

Blood Pressure | Energy Expenditure | Substrate Oxidation

Slovenia
University of Minnesota

Completed

Identifying the Brain Substrates of Hypoglycemia Unawareness in Type 1 Diabetes

Hypoglycemia

United States
Rigshospitalet, Denmark

Completed

IL-6 Regulation of Substrate Metabolism and Influence of Obesity

Healthy | Obesity

Denmark
Northern Illinois University

Completed

Pre-workout Supplement Versus Caffeine on Energy Expenditure.

Healthy

United States
Maastricht University Medical Center

Completed

Inulin and Acetate Production and Human Substrate Metabolism

Obesity | Pre Diabetes

Netherlands
University of Alberta
Almased Wellness GmbH

Completed

The Impact of a High Protein Diet on Substrate Oxidation and Energy Metabolism

Dietary Modification

Canada
Plexus Worldwide
George Mason University

Unknown

The Acute Effect of Grains of Paradise (Aframomum Melegueta) on REE

Obesity
University of Bath

Completed

Substrate Metabolism During Exercise Following Ingestion of Ethanol

Exercise Metabolism Following Ethanol Ingestion

United Kingdom
University Hospital, Clermont-Ferrand

Unknown

Comparison of the Use of Energy Substrates and Hormonal Regulation of Blood Sugar During Exercise of Increasing Intensity Between Children With Type 1 Diabetes and Non-diabetic Control Children. (DIABSPORT)

Type 1 Diabetes

France
Amicus Therapeutics

Completed

A 12-Week Safety and Pharmacodynamic Study of AT1001 (Migalastat Hydrochloride) in Participants With Fabry Disease

Fabry Disease

Australia, Brazil
Amicus Therapeutics

Completed

Study of the Effects of Oral AT1001 (Migalastat Hydrochloride) in Patients With Fabry Disease

Fabry Disease

United States, Italy, Spain, Turkey, Brazil, Canada, United Kingdom, France, Poland, Australia, Egypt, Argentina, Denmark
Amicus Therapeutics

Completed

A Study of AT1001 (Migalastat Hydrochloride) in Participants With Fabry Disease

Fabry Disease

United States
University of Lausanne

Completed

Fructose Extra-splanchnic Metabolism and Its Effects on Systemic Flux of Substrates (FruPP) (FruPP)

Test Meal

Switzerland
Amicus Therapeutics

Completed

A 12-Week Safety and Pharmacodynamic Study of AT1001 (Migalastat Hydrochloride) in Female Participants With Fabry Disease

Fabry Disease

United States, Australia, France, United Kingdom, Brazil, Canada
Amicus Therapeutics

Terminated

Open-label Long-term Safety Study of AT1001 (Migalastat Hydrochloride) in Participants With Fabry Disease Who Have Completed a Previous AT1001 Study

Fabry Disease

United Kingdom, United States, Australia, Brazil, France
Amicus Therapeutics

Completed

A 24-Week Safety and Pharmacodynamic Study of AT1001 (Migalastat Hydrochloride) in Participants With Fabry Disease

Fabry Disease

France, United Kingdom
Maastricht University Medical Center
Nederlandse Zuivel Organisatie

Completed

Effect of Different Protein Diets on Glucose and Insulin Metabolism and Substrate Partitioning

Insulin | Glucose Metabolism
Ottawa Heart Institute Research Corporation
Heart and Stroke Foundation of Ontario

Completed

Rt Ventricular Substrate Metabolism as a Predictor of Rt Heart Failure in Patients With Pulmonary Arterial Hypertension (RVMET)

Pulmonary Arterial Hypertension

Canada
Northumbria University
Bayer

Completed

Effects of Supradyn® Energy 3RDA on Fatigue/Stress, Substrate Metabolism During Exercise and Demanding Cognitive Tasks

Healthy

United Kingdom
University of Aarhus
Aarhus University Hospital

Completed

Substrate Metabolism and Insulin Sensitivity in Acromegalic Patients Before and After Treatment

Insulin Resistance | Acromegaly | Excessive Growth Hormone Secretion

Denmark
University of Aarhus
Aarhus University Hospital

Withdrawn

Substrate Metabolism and Insulin Sensitivity in Patients With Hyperprolactinemia Before and After Treatment

Insulin Resistance | Hyperprolactinemia

Denmark
University of Aarhus
Aarhus University Hospital

Terminated

Insulin Sensitivity and Substrate Metabolism in Patients With Cushing's Syndrome

Insulin Resistance | Cushing's Syndrome

Denmark

Search clinical trials for: substrate metabolism

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