Is Sjögren's Syndrome Associated With Meibomian Gland Dysfunction ?

Is Sjögren's Syndrome Associated With Meibomian Gland Dysfunction ?

Sponsoren

Hauptsponsor: Tung Wah Hospital

Quelle Tung Wah Hospital
Kurze Zusammenfassung

The investigators hypothesize that the dry eye caused by SS may include the evaporative type, resulting from the MGD. Furthermore, the investigators hypothesize that both pSS and sSS are associated with MGD.To test our hypothesis, we conducted a prospective clinical study in patients with SS (both pSS and sSS) and MGD, and the normal population All subjects were matched for both age and gender and assessed for tear function and ocular surface signs and symptoms.

Gesamtstatus Unknown status
Anfangsdatum May 1, 2017
Fertigstellungstermin September 1, 2017
Primäres Abschlussdatum August 1, 2017
Phase N/A
Studientyp Interventional
Primärer Ausgang
Messen Zeitfenster
meibomian gland function up to 3 months after tear substitutes apply
Ocular Surface Disease Index up to 3 months after tear substitutes apply
noninvasive tear breakup time up to 3 months after tear substitutes apply
fluorescein staining of the cornea up to 3 months after tear substitutes apply
Schirmer's test with and without anesthesia up to 3 months after tear substitutes apply
tear meniscus up to 3 months after tear substitutes apply
Sekundäres Ergebnis
Messen Zeitfenster
rose bengal staining of the conjunctiva up to 3 months after tear substitutes apply
Einschreibung 80
Bedingung
Intervention

Interventionsart: Drug

Interventionsname: Tears Naturale Forte

Beschreibung: This medication is used to relieve dry, irritated eyes

Anderer Name: DEXTRAN/HYPROMELLOSE/GLYCERIN

Interventionsart: Drug

Interventionsname: liposic

Beschreibung: Liposic eye gel contain the active ingredient carbomer, which is a type of medicine known as an eye lubricant. It is used for the treatment of the symptoms of dry eye.

Anderer Name: Carbomer

Teilnahmeberechtigung

Kriterien:

Inclusion Criteria:

- All the subjects are female and age between 50-60 years

- Patients with primary SS fulfilled the criteria established by the European Study Group

- Patients with SLE and RA met the criteria set by the American College of Rheumatology

Exclusion Criteria:

- The control history of autoimmune disease

Geschlecht: Female

Mindestalter: 50 Years

Maximales Alter: 60 Years

Gesunde Freiwillige: Accepts Healthy Volunteers

Insgesamt offiziell
Nachname Rolle Zugehörigkeit
Shaolin Du, MD,PhD Principal Investigator Tungwah Hospital of Sun Yat-Sen University
Gesamtkontakt

Nachname: Chi Zhang, MD,PhD

Telefon: +8613790077756

Email: [email protected]

Ort
Einrichtung: Status: Kontakt: Tungwah Hospital of Sun Yat-sen University Chi Zhang, MD,PhD +8613790077756 [email protected]
Standort Länder

China

Überprüfungsdatum

May 2017

Verantwortliche Partei

Art: Sponsor

Schlüsselwörter
Hat den Zugriff erweitert No
Bedingung Durchsuchen
Anzahl der Waffen 4
Armgruppe

Etikette: primary Sjögren's syndrome

Art: Experimental

Beschreibung: The female patients with primary Sjögren's syndrome receive the Tears Naturale Forte and Liposic.

Etikette: secondary Sjögren's syndrome

Art: Experimental

Beschreibung: The female patients with secondary Sjögren's syndrome receive Tears Naturale Forte and Liposic.

Etikette: meibomian gland dysfunction

Art: Experimental

Beschreibung: The female patients with meibomian gland dysfunction receive the Tears Naturale Forte and Liposic.

Etikette: control

Art: Experimental

Beschreibung: the female had no history of autoimmune disease receive the Tears Naturale Forte and Liposic.

Studiendesign Info

Zuweisung: Non-Randomized

Interventionsmodell: Parallel Assignment

Hauptzweck: Treatment

Maskierung: None (Open Label)

Quelle: ClinicalTrials.gov