Cervical tsDCS on Stroke Patients (AMPLI-MOV)
Clinical and Neurophysiological Evaluation of the Effects of Cervical tsDCS on Stroke Patients With Distal Upper Limb Strength Deficit
The present project aims to evaluate the facilitatory modulation of motor responses of the limb upper limb by tsDCS in patients with arm/hand hyposthenia after cerebral ischemia to verify the possible therapeutic benefits that this type of stimulation can induce in terms of of strength, dexterity and effectiveness in acts of daily living.
調査の概要
研究の種類
入学 (推定)
段階
- 適用できない
連絡先と場所
研究連絡先
- 名前：Fabrizio Vecchio
- 電話番号：3478031201
- メール：fabrizio.vecchio@sanraffaele.it
研究場所
-
-
RM
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Roma、RM、イタリア、00166
- 募集
- IRCCS San Raffaele Roma
-
コンタクト：
- Fabrizio Vecchio
- 電話番号：+39-06-52253767
- メール：fabrizio.vecchio@sanraffaele.it
-
-
Rome
-
Rome、Rome、イタリア、00163
- まだ募集していません
- IRCCS San Raffaele Roma
-
コンタクト：
- Fabrizio v
- 電話番号：3478031201
- メール：fabrizio.vecchio@sanraffaele.it
-
-
参加基準
適格基準
就学可能な年齢
健康ボランティアの受け入れ
受講資格のある性別
説明
Group Stroke:
Inclusion criteria:
- age over 18 years;
- first ischemic/hemorrhagic stroke (within 30 days of onset);
- mild-to-moderate stroke (NIHSS scale score<16).
- residual function of the upper limb, assessed by the following scales: - MRC of the distal muscles of the upper limb: score between 2 and 4; - NHISS (items 5A and 5B): score between 1 and 3;
- ability to give informed consent and understand instructions.
Exclusion criteria:
- severe spasticity (Ashworth Scale score > 2);
- severe aphasia;
- severe neglect;
- history of disabling neurological disease;
- history of epilepsy;
- significant comorbidities;
- contraindications to tsDCS.
Healthy Group:
Inclusion criteria:
- age over 18 years;
- equalized in age with the patient group.
Exclusion criteria:
- history of stroke progress;
- history of severe neurological disease.
研究計画
研究はどのように設計されていますか？
デザインの詳細
- 主な目的：処理
- 割り当て：ランダム化
- 介入モデル：クロスオーバー割り当て
- マスキング：独身
武器と介入
参加者グループ / アーム |
介入・治療 |
|---|---|
|
実験的：健康
|
Transcranial direct current stimulation |
|
実験的：脳卒中
|
Transcranial direct current stimulation |
この研究は何を測定していますか？
主要な結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
|
improvement of paretic hand performance
時間枠：through study completion, an average of 1 year
|
The primary outcome measure is the improvement in hand strength and dexterity in individuals with upper limb motor impairment following cerebral ischemia, after the application of tsDCS at the cervical spinal level during Reaching |
through study completion, an average of 1 year
|
|
improvement of paretic hand performance
時間枠：through study completion, an average of 1 year
|
The primary outcome measure is the improvement in hand strength and dexterity in individuals with upper limb motor impairment following cerebral ischemia, after the application of tsDCS at the cervical spinal level during Grasping |
through study completion, an average of 1 year
|
|
improvement of paretic hand performance
時間枠：through study completion, an average of 1 year
|
The primary outcome measure is the improvement in hand strength and dexterity in individuals with upper limb motor impairment following cerebral ischemia, after the application of tsDCS at the cervical spinal level during Lifting test |
through study completion, an average of 1 year
|
|
improvement of paretic hand performance
時間枠：through study completion, an average of 1 year
|
The primary outcome measure is the improvement in hand strength and dexterity in individuals with upper limb motor impairment following cerebral ischemia, after the application of tsDCS at the cervical spinal level duringthe Nine Hole Peg test |
through study completion, an average of 1 year
|
|
improvement of paretic hand performance
時間枠：through study completion, an average of 1 year
|
The primary outcome measure is the improvement in hand strength and dexterity in individuals with upper limb motor impairment following cerebral ischemia, after the application of tsDCS at the cervical spinal level during finger mobility tests |
through study completion, an average of 1 year
|
協力者と研究者
スポンサー
研究記録日
主要日程の研究
研究開始 (実際)
一次修了 (推定)
研究の完了 (推定)
試験登録日
最初に提出
QC基準を満たした最初の提出物
最初の投稿 (実際)
学習記録の更新
投稿された最後の更新 (実際)
QC基準を満たした最後の更新が送信されました
最終確認日
詳しくは
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