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屋内の過熱が子供の生理的負担に与える影響

2026年11月9日 更新者:Glen P. Kenny、University of Ottawa

26°Cの室内温度制限が子どもの生理的反応に及ぼす効果に関する予備的研究

Communities worldwide are experiencing increasing heat extremes that challenge the limits of human thermoregulation, particularly among vulnerable populations such as children. Compared with adults, children are more susceptible to heat related illness due to less efficient thermoregulatory systems and difficulty recognizing early signs of heat stress. In addition, prolonged heat exposure can adversely affect their mental health, contributing to cognitive decline, heightened anxiety, and irritability. As children spend substantial time in hot environments at school and at home, and as these conditions intensify with climate change, actions to safeguard their health are essential. Yet our understanding of heat exposure effects in children remains incomplete, hindering the development of evidence based strategies to protect them.

To address this gap, the investigators aim to evaluate whether an indoor temperature limit of 26 °C (45 percent relative humidity), the upper threshold recommended to protect older adults, can effectively prevent dangerous increases in physiological strain and declines in cognitive function in children during a simulated daylong heatwave. The preliminary study will assess physiological and cognitive responses in children aged 10 to 15 years and adults aged 20 to 30 years during a 6 hour exposure (approximating a typical school day) to two conditions: (1) the recommended indoor temperature upper limit (26 °C) and (2) a high heat condition representative of homes and schools without air conditioning during extreme heat events (36 °C). In both conditions, children will remain seated at rest while wearing light clothing (t shirt and shorts), with the exception of performing 15 minutes of stepping exercise (6-6.5 METS) each hour (excluding the lunch period) to reflect typical daily activity in a school setting. This experimental design will allow investigators to determine whether maintaining indoor temperatures at the recommended upper limit for older adults sufficiently mitigates physiological strain in children.

調査の概要

状態

積極的、募集していない

研究の種類

介入

入学 (推定)

10

段階

  • 適用できない

連絡先と場所

このセクションには、調査を実施する担当者の連絡先の詳細と、この調査が実施されている場所に関する情報が記載されています。

研究場所

    • Ontario
      • Ottawa、Ontario、カナダ、K1N 6N5
        • University of Ottawa

参加基準

研究者は、適格基準と呼ばれる特定の説明に適合する人を探します。これらの基準のいくつかの例は、人の一般的な健康状態または以前の治療です。

適格基準

就学可能な年齢

10年~30年 (子、大人)

健康ボランティアの受け入れ

はい

受講資格のある性別

全て

説明

Inclusion Criteria:

  • English or French speaking.
  • Ability to provide informed assent.
  • Children aged 10-15 years and adults aged 20-30 years.

Exclusion Criteria:

  • Chronic health conditions
  • Endurance exercise training (greater than 3 sessions of vigorous exercise training per week for 30 minutes or more)
  • Restrictions to physical activity

研究計画

このセクションでは、研究がどのように設計され、研究が何を測定しているかなど、研究計画の詳細を提供します。

研究はどのように設計されていますか?

デザインの詳細

  • 主な目的:基礎科学
  • 割り当て:ランダム化
  • 介入モデル:クロスオーバー割り当て
  • マスキング:独身

武器と介入

参加者グループ / アーム
介入・治療
実験的:Exposure to indoor temperature upper limit of 26°C

Participants exposed daylong (6 hours) to an indoor temperature maintained at 26°C and 45% relative humidity (humidex equivalent of 29).

Children exposed to a 6-hour simulated heat exposure

実験的:Exposure to hot indoor environment of 36°C

Participants exposed daylong (6 hours) to an indoor temperature maintained at 36°C and 45% relative humidity (humidex equivalent of 45).

Children exposed to a 6-hour simulated heat exposure

この研究は何を測定していますか?

主要な結果の測定

結果測定
メジャーの説明
時間枠
Core temperature (Peak) during daylong exposure to indoor overheating
時間枠:End of 6 hour daylong exposure

Peak visceral temperature (15 min average) during exposure. Visceral temperature is measured continuously throughout the 6 hour exposure to the simulated indoor overheating. A 0.2°C between-group difference will be considered the smallest physiologically meaningful effect.

End of 6 hour daylong exposure

二次結果の測定

結果測定
メジャーの説明
時間枠
Fluid loss during daylong exposure to indoor overheating
時間枠:At end of 6 hour daylong exposure

Fluid loss calculated as the change in body mass during each exposure presented as a percentage of baseline body mass (corrected for food consumption).

At end of 6 hour daylong exposure
Fluid consumption during daylong exposure to indoor overheating
時間枠:At end of 6 hour daylong exposure

Average hourly fluid consumption calculated by weighing participant water intake at the start and end of each hour of exposure (normalized to the exposure duration).

At end of 6 hour daylong exposure
Hydration status during daylong exposure to indoor overheating
時間枠:At the start (hour 0) and end of 6 hour daylong exposure

Hydration status measured via assessing the urine specific gravity of a urine sample.

At the start (hour 0) and end of 6 hour daylong exposure
Executive function during daylong exposure to indoor overheating (cognitive function).
時間枠:At the start (hour 0) and end of 6 hour daylong exposure

Participants will be provided with a tablet device with the Sway Medical testing platform for the assessment of executive function. Participants will complete the Cued Stroop test, in which they are presented a sequence of congruent, neutral and incongruent color-word tasks.

At the start (hour 0) and end of 6 hour daylong exposure
CDC 4-Stage Balance Test during daylong exposure to indoor overheating (postural stability).
時間枠:At the start (hour 0) and end of 6 hour daylong exposure

To assess postural stability, participants hold a tablet to their chest, then auditory cues guide participants through four consecutive stances, feet side by side, instep of one foot touching the big toe of the other foot, tandem stand with one foot in front of the other, heel touching toe, and stand on one foot. The balance assessment will be evaluated based on movement detected by an accelerometer integrated into the hardware of the tablet device (Sway Medical Inc).

At the start (hour 0) and end of 6 hour daylong exposure
Memory recall during daylong exposure to indoor overheating (cognitive function).
時間枠:At the start (hour 0) and end of 6 hour daylong exposure

Participants will be provided with a tablet device with the Sway Medical testing platform for the assessment of memory recall. Participants complete both a delayed recall test and a working memory test.

At the start (hour 0) and end of 6 hour daylong exposure
Impulse control during daylong exposure to indoor overheating (cognitive function).
時間枠:At the start (hour 0) and end of 6 hour daylong exposure

Participants will be provided with a tablet device with the Sway Medical testing platform for the assessment of impulse control. Participants will be asked to respond to both "go" and "no-go" visual cues. In response to the "go" cue, participants will initiate a movement of the device.

At the start (hour 0) and end of 6 hour daylong exposure
Reaction time during daylong exposure to indoor overheating (cognitive function).
時間枠:At the start (hour 0) and end of 6 hour daylong exposure

Participants will be provided with a tablet device with the Sway Medical testing platform for the assessment of reaction time. Participants will be asked to initiate a movement of the device in response to a visual cue.

At the start (hour 0) and end of 6 hour daylong exposure
Diastolic blood pressure during daylong exposure to indoor overheating.
時間枠:At the start (hour 0) and end of 6 hour daylong exposure

Diastolic blood pressure measured in triplicate via automated oscillometry (~60 seconds between measures).

At the start (hour 0) and end of 6 hour daylong exposure
Systolic blood pressure during daylong exposure to indoor overheating
時間枠:At the start (hour 0) and end of 6 hour daylong exposure

Systolic blood pressure measured in triplicate via automated oscillometry (~60 seconds between measures).

At the start (hour 0) and end of 6 hour daylong exposure
Heart rate end of daylong exposure to indoor overheating
時間枠:End of 6 hour daylong exposure

Heart rate measured at hour 6 of exposure to indoor overheating (15-min average).

End of 6 hour daylong exposure
Heart rate (AUC) during daylong exposure to indoor overheating
時間枠:End of 6 hour daylong exposure

Areas under the curve (AUC) of heart rate during the 6 hour exposure to the simulate indoor overheating.

End of 6 hour daylong exposure
Heat rate (Peak) during daylong exposure to indoor overheating
時間枠:End of 6 hour daylong exposure

Peak heart rate (15 min average) during exposure. Heart rate is measured continuously throughout the 6 hour exposure to the simulated indoor overheating.

End of 6 hour daylong exposure
Mean skin temperature end of daylong exposure to indoor overheating
時間枠:End of 6 hour daylong exposure

Mean skin temperature measured over 7 body regions at hour 6 of exposure to indoor overheating (15-min average).

End of 6 hour daylong exposure
Mean skin temperature (AUC) during daylong exposure to indoor overheating
時間枠:End of 6 hour daylong exposure

Areas under the curve (AUC) of mean skin temperature as calculated over 7 body regions during the 6 hour exposure to the simulate indoor overheating.

End of 6 hour daylong exposure
Mean skin temperature (Peak) during daylong exposure to indoor overheating
時間枠:End of 6 hour daylong exposure

Peak mean skin temperature (15 min average) during exposure. Mean skin temperature as calculated from skin temperature measured across 7 body regions is measured continuously throughout the 6 hour exposure to the simulated indoor overheating.

End of 6 hour daylong exposure
Core temperature end of daylong exposure to indoor overheating
時間枠:End of 6 hour daylong exposure

Visceral temperature measured at hour 6 of exposure to indoor overheating (15-min average).

End of 6 hour daylong exposure
Core temperature (AUC) during daylong exposure to indoor overheating
時間枠:End of 6 hour daylong exposure

Areas under the curve (AUC) of visceral temperature during the 6 hour exposure to the simulate indoor overheating.

End of 6 hour daylong exposure
Profiles of Mood States (POMS) during daylong exposure to indoor overheating
時間枠:At the start (hour 0) and end of 6 hour daylong exposure

Potential changes in mood (7 subscales of mood: tension, anger, depression, fatigue, confusion, vigor and esteem related affect). The POMS-40 is a validated, self-administered questionnaire that examines seven distinct aspects of mood state across two positive subscales (Esteem-Related Affect, and Vigor) and five negative subscales (Fatigue, Tension, Confusion, Anger, and Depression), which are described across 40 distinct adjectives. For each individual item, participants were asked to describe "how you feel right now" by responding using a 5-point Likert scale (0 = "Not at all", 1 = "A little", 2 = "Moderately", 3 = "Quite a lot", or 4 = "Extremely"). The values of items associated with a specific subscale (e.g., Fatigue) were summed to calculate its score.

At the start (hour 0) and end of 6 hour daylong exposure
Environmental Symptoms Questionnaire (ESQ) during daylong exposure to indoor overheating
時間枠:At the start (hour 0) and end of 6 hour daylong exposure

Self-reported environmental reactions and medical symptomatology associated with prolonged heat exposure. The ESQ-IV is a validated 68-item, self-administered questionnaire that has been used successfully in identifying symptomatology during exposure to a wide variety of environmental conditions, including heat exposure.

Participants are asked to assess and described "how you have been feeling today" by responding to each item using a 6-point Likert scale (0 = "Not at all", 1 = "Slight", 2 = "Somewhat", 3 = "Moderate", 4 = "Quite a bit", or 5 = "Extreme"). Total Symptom Score was calculated from this data by taking the sum of the intensity ratings from all 68 individual items using reverse scores for the three positive items from the list ("I Felt Good", "I Felt Alert", and "I Felt Wide Awake").

At the start (hour 0) and end of 6 hour daylong exposure
Perceived exertion scale during daylong exposure to indoor temperature limit.
時間枠:At the start (hour 0) and end of 6 hour daylong exposure

Perceived exertional assessed via a visual analog scale ("How hard are you working?") ranging from "no exertional at all" to "maximal exertion"

At the start (hour 0) and end of 6 hour daylong exposure
Activity levels during daylong exposure to indoor overheating
時間枠:End of 6 hour daylong exposure

Activity levels assessed via a wearable monitor (Actical) containing an accelerometer worn on the wrist and hip.

End of 6 hour daylong exposure
Feel good scale during daylong exposure to indoor overheating
時間枠:At the start (hour 0) and end of 6 hour daylong exposure

Feel good scale assessed via a visual analog scale (How good do you feel?) ranging from "very good" to "very bad" (midpoint: neutral)

At the start (hour 0) and end of 6 hour daylong exposure
Thirst sensation scale during daylong exposure to indoor overheating
時間枠:At the start (hour 0) and end of 6 hour daylong exposure

Thirst sensation assessed via a visual analog scale ranging from very, very thirsty to not thirsty at all.

At the start (hour 0) and end of 6 hour daylong exposure
Thermal comfort scale during daylong exposure to indoor overheating
時間枠:At the start (hour 0) and end of 6 hour daylong exposure

Thermal comfort assessed via a visual analog scale ("How comfortable does your body temperature feel?") ranging from "very uncomfortable" to "comfortable".

At the start (hour 0) and end of 6 hour daylong exposure
Thermal sensation 2 scale during daylong exposure to indoor overheating
時間枠:At the start (hour 0) and end of 6 hour daylong exposure

Thermal sensation assessed via a visual analog scale ("How do you feel?") ranging from "hot" to "cold"(midpoint: neutral)

At the start (hour 0) and end of 6 hour daylong exposure
Thermal sensation scale during daylong exposure to indoor overheating
時間枠:At the start (hour 0) and end of 6 hour daylong exposure

Thermal sensation assessed via a visual analog scale (How hot do you feel?) ranging from "extremely hot" to "neutral".

At the start (hour 0) and end of 6 hour daylong exposure
BTrackS Balance Assessment during daylong exposure to indoor overheating (postural stability).
時間枠:At the start (hour 0) and end of 6 hour daylong exposure

To assess postural stability, participants will be asked to stand on a BTracks force plate with their feet spread out to shoulder width, hand on their hips and eyes closed. The assessment will comprise of four trials (one practice trial) lasting 20 seconds in length and 20 seconds between trials. Center of pressure (COP) vector data along vertical (y) and horizontal (x) axes will be summed for the total path excursion length (cm) during each trial

At the start (hour 0) and end of 6 hour daylong exposure

協力者と研究者

ここでは、この調査に関係する人々や組織を見つけることができます。

スポンサー

捜査官

  • 主任研究者:Glen P Kenny, PhD、University of Ottawa

研究記録日

これらの日付は、ClinicalTrials.gov への研究記録と要約結果の提出の進捗状況を追跡します。研究記録と報告された結果は、国立医学図書館 (NLM) によって審査され、公開 Web サイトに掲載される前に、特定の品質管理基準を満たしていることが確認されます。

主要日程の研究

研究開始 (実際)

2025年11月8日

一次修了 (実際)

2026年4月27日

研究の完了 (推定)

2026年12月31日

試験登録日

最初に提出

2025年11月21日

QC基準を満たした最初の提出物

2025年11月21日

最初の投稿 (実際)

2025年12月3日

学習記録の更新

投稿された最後の更新 (実際)

2026年11月12日

QC基準を満たした最後の更新が送信されました

2026年11月9日

最終確認日

2026年11月1日

詳しくは

本研究に関する用語

医薬品およびデバイス情報、研究文書

米国FDA規制医薬品の研究

いいえ

米国FDA規制機器製品の研究

いいえ

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