Canadian University Health Network conducts a clinical trial of Multicenter Validation of a Predictor Model of ACHD Patients and Cardiac Surgery
The University Health Network, Toronto is conducting the clinical trial Multicenter Validation of a Predictor Model of ACHD Patients and Cardiac Surgery.
This study is to validate prediction modeling for the ACHD population undergoing cardiac surgery. The validation of this prediction model will support and generalize its use as a risk stratification tool in the ACHD population.
It is planned to include 1000 participants.
Actual study start date is March 10, 2020. The researchers expect to complete the study by March 2023.
One primary outcome measure is Composite adverse events, The composite adverse outcome is defined by in-hospital mortality, prolonged ventilation (exceeding seven days), or acute kidney injury requiring dialysis.
Among study population are all ACHD patients undergoing cardiac surgery in TGH and the other collaborating cardiac centers.
Among collaborators are: Providence Healthcare, Montreal Heart Institute, Westmead Hospital, (Sydney, New South Wales, Australia), the Prince Charles Hospital, Royal Children's Hospital, Auckland City Hospital, Mater Misericordiae University Hospital, and Newcastle-upon-Tyne Hospitals NHS Trust.
There are a number of conditions that do not allow participation, such as:
- CHD patients <16 years of age
- ACHD patients undergoing chest wall debridement and chest re-explorations for bleeding
- Non-cardiac surgery procedures and cardiology laboratory interventions
The location of the study is as follows (further details can be found here https://ichgcp.net/clinical-trials-registry/NCT04787705) Toronto, Canada.
