Deze pagina is automatisch vertaald en de nauwkeurigheid van de vertaling kan niet worden gegarandeerd. Raadpleeg de Engelse versie voor een brontekst.

Gerichte therapie op basis van genetische tests bij de behandeling van patiënten met vergevorderde refractaire vaste tumoren, lymfomen of multipel myeloom (de MATCH-screeningproef)

23 oktober 2026 bijgewerkt door: National Cancer Institute (NCI)

Moleculaire analyse voor therapiekeuze (MATCH)

This phase II MATCH screening and multi-sub-trial studies how well treatment that is directed by genetic testing works in patients with solid tumors, lymphomas, or multiple myelomas that may have spread from where it first started to nearby tissue, lymph nodes, or distant parts of the body (advanced) and does not respond to treatment (refractory). Patients must have progressed following at least one line of standard treatment or for which no agreed upon treatment approach exists. Genetic tests look at the unique genetic material (genes) of patients' tumor cells. Patients with genetic abnormalities (such as mutations, amplifications, or translocations) may benefit more from treatment which targets their tumor's particular genetic abnormality. Identifying these genetic abnormalities first may help doctors plan better treatment for patients with solid tumors, lymphomas, or multiple myeloma.

Studie Overzicht

Toestand

Toestand

Geeft de huidige wervingsstatus of de uitgebreide toegangsstatus aan.
Actief, niet wervend

Conditie

Conditie

De ziekte, stoornis, syndroom, aandoening of verwonding die wordt bestudeerd. Op ClinicalTrials.gov kunnen aandoeningen ook andere gezondheidsgerelateerde problemen omvatten, zoals levensduur, kwaliteit van leven en gezondheidsrisico's.

Interventie / Behandeling

Interventie / Behandeling

Een proces of actie die centraal staat in een klinische studie. Interventies omvatten medicijnen, medische hulpmiddelen, procedures, vaccins en andere producten die in onderzoek zijn of al beschikbaar zijn. Interventies kunnen ook niet-invasieve benaderingen omvatten, zoals onderwijs of het aanpassen van voeding en lichaamsbeweging.

Gedetailleerde beschrijving

PRIMARY OBJECTIVE:

I. To evaluate the proportion of patients with objective response (OR) to targeted study agent(s) in patients with advanced refractory cancers/lymphomas/multiple myeloma.

SECONDARY OBJECTIVES:

I. To evaluate the proportion of patients alive and progression free at 6 months of treatment with targeted study agent in patients with advanced refractory cancers/lymphomas/multiple myeloma.

II. To evaluate time until death or disease progression. III. To identify potential predictive biomarkers beyond the genomic alteration by which treatment is assigned or resistance mechanisms using additional genomic, ribonucleic acid (RNA), protein and imaging-based assessment platforms.

IV. To assess whether radiomic phenotypes obtained from pre-treatment imaging and changes from pre- through post-therapy imaging can predict objective response and progression free survival and to evaluate the association between pre-treatment radiomic phenotypes and targeted gene mutation patterns of tumor biopsy specimens.

OUTLINE:

STEP 0 (Screening): Patients undergo biopsy along with molecular characterization of the biopsy material for specific, pre-defined mutations, amplifications, or translocations of interest via tumor sequencing and immunohistochemistry. Consenting patients also undergo collection of blood samples for research purposes.

STEPS 1, 3, 5, 7 (Treatment): Patients are assigned to 1 of 38 treatment subprotocols based on molecularly-defined subgroup. (See Arms Section)

STEPS 2, 4, 6 (Screening): Patients experiencing disease progression on the prior Step treatment or who could not tolerate the assigned treatment undergo review of their previous biopsy results to determine if another treatment is available or undergo another biopsy. Patients may have a maximum of 2 screening biopsies and 2 treatments per biopsy.

STEP 8 (Optional Research): Consenting patients undergo end-of-treatment biopsy and collection of blood samples for research purposes.

Additionally, patients may undergo a computed tomography (CT) scan, magnetic resonance imaging, and/or radionuclide imaging throughout the trial.

After completion of study treatment, patients are followed up every 3 months for 2 years and then every 6 months for 1 year.

Studietype

Studietype

Beschrijft de aard van een klinische studie. Onderzoekstypen omvatten interventionele studies (ook wel klinische studies genoemd), observationele studies (inclusief patiëntenregistraties) en uitgebreide toegang.
Ingrijpend

Inschrijving (Geschat)

Inschrijving

Het aantal deelnemers aan een klinische studie. De "verwachte" inschrijving is het beoogde aantal deelnemers dat de onderzoekers nodig hebben voor het onderzoek.
6452

Fase

Fase

De fase van een klinische proef waarin een medicijn of biologisch product wordt bestudeerd, gebaseerd op definities die zijn ontwikkeld door de Amerikaanse Food and Drug Administration (FDA). De fase is gebaseerd op het doel van het onderzoek, het aantal deelnemers en andere kenmerken. Er zijn vijf fasen: vroege fase 1 (voorheen vermeld als fase 0), fase 1, fase 2, fase 3 en fase 4. Niet van toepassing wordt gebruikt om onderzoeken te beschrijven zonder door de FDA gedefinieerde fasen, inclusief onderzoeken van apparaten of gedragsinterventies.
  • Fase 2

Contacten en locaties

In dit gedeelte vindt u de contactgegevens van degenen die het onderzoek uitvoeren en informatie over waar dit onderzoek wordt uitgevoerd.

Studie Locaties

  • Guam
      • Tamuning, Guam, 96913
        • FHP Health Center-Guam
  • Puerto Rico
      • Bayamón, Puerto Rico, 00959-5060
        • Cancer Center-Metro Medical Center Bayamon
      • Manati, Puerto Rico, 00674
        • Doctors Cancer Center
      • San Juan, Puerto Rico, 00917
        • San Juan Community Oncology Group
      • San Juan, Puerto Rico, 00936
        • San Juan City Hospital
  • Verenigde Staten
    • Alabama
      • Birmingham, Alabama, Verenigde Staten, 35233
        • University of Alabama at Birmingham Cancer Center
      • Fairhope, Alabama, Verenigde Staten, 36532
        • Thomas Hospital
      • Mobile, Alabama, Verenigde Staten, 36688
        • University of South Alabama Mitchell Cancer Institute
      • Mobile, Alabama, Verenigde Staten, 36607
        • Mobile Infirmary Medical Center
    • Alaska
      • Anchorage, Alaska, Verenigde Staten, 98508
        • Anchorage Associates in Radiation Medicine
      • Anchorage, Alaska, Verenigde Staten, 99508
        • Alaska Breast Care and Surgery LLC
      • Anchorage, Alaska, Verenigde Staten, 99508
        • Alaska Oncology and Hematology LLC
      • Anchorage, Alaska, Verenigde Staten, 99508
        • Alaska Women's Cancer Care
      • Anchorage, Alaska, Verenigde Staten, 99508
        • Anchorage Oncology Centre
      • Anchorage, Alaska, Verenigde Staten, 99508
        • Katmai Oncology Group
      • Anchorage, Alaska, Verenigde Staten, 99508
        • Providence Alaska Medical Center
      • Anchorage, Alaska, Verenigde Staten, 99504
        • Anchorage Radiation Therapy Center
      • Anchorage, Alaska, Verenigde Staten, 99508
        • Alaska Regional Hospital
      • Fairbanks, Alaska, Verenigde Staten, 99701
        • Fairbanks Memorial Hospital
    • Arizona
      • Goodyear, Arizona, Verenigde Staten, 85338
        • CTCA at Western Regional Medical Center
      • Kingman, Arizona, Verenigde Staten, 86401
        • Kingman Regional Medical Center
      • Phoenix, Arizona, Verenigde Staten, 85054
        • Mayo Clinic Hospital in Arizona
      • Phoenix, Arizona, Verenigde Staten, 85004
        • Cancer Center at Saint Joseph's
      • Phoenix, Arizona, Verenigde Staten, 85013
        • Saint Joseph's Hospital and Medical Center
      • Scottsdale, Arizona, Verenigde Staten, 85259
        • Mayo Clinic in Arizona
    • Arkansas
      • Fort Smith, Arkansas, Verenigde Staten, 72903
        • Mercy Hospital Fort Smith
      • Hot Springs, Arkansas, Verenigde Staten, 71913
        • CHI Saint Vincent Cancer Center Hot Springs
      • Jonesboro, Arkansas, Verenigde Staten, 72401
        • NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro
      • Little Rock, Arkansas, Verenigde Staten, 72205
        • University of Arkansas for Medical Sciences
    • California
      • Anaheim, California, Verenigde Staten, 92806
        • Kaiser Permanente-Anaheim
      • Antioch, California, Verenigde Staten, 94531
        • Kaiser Permanente-Deer Valley Medical Center
      • Arroyo Grande, California, Verenigde Staten, 93420
        • PCR Oncology
      • Arroyo Grande, California, Verenigde Staten, 93420
        • Mission Hope Medical Oncology - Arroyo Grande
      • Auburn, California, Verenigde Staten, 95602
        • Sutter Auburn Faith Hospital
      • Auburn, California, Verenigde Staten, 95603
        • Sutter Cancer Centers Radiation Oncology Services-Auburn
      • Bakersfield, California, Verenigde Staten, 93301
        • AIS Cancer Center at San Joaquin Community Hospital
      • Baldwin Park, California, Verenigde Staten, 91706
        • Kaiser Permanente-Baldwin Park
      • Bellflower, California, Verenigde Staten, 90706
        • Kaiser Permanente-Bellflower
      • Berkeley, California, Verenigde Staten, 94704
        • Alta Bates Summit Medical Center-Herrick Campus
      • Burbank, California, Verenigde Staten, 91505
        • Providence Saint Joseph Medical Center/Disney Family Cancer Center
      • Burlingame, California, Verenigde Staten, 94010
        • Mills-Peninsula Medical Center
      • Cameron Park, California, Verenigde Staten, 95682
        • Sutter Cancer Centers Radiation Oncology Services-Cameron Park
      • Castro Valley, California, Verenigde Staten, 94546
        • Eden Hospital Medical Center
      • Clovis, California, Verenigde Staten, 93611
        • Community Cancer Institute
      • Clovis, California, Verenigde Staten, 93611
        • University Oncology Associates
      • Concord, California, Verenigde Staten, 94520
        • John Muir Medical Center-Concord
      • Corona, California, Verenigde Staten, 92882
        • City of Hope Corona
      • Costa Mesa, California, Verenigde Staten, 92627
        • UC Irvine Health Cancer Center-Newport
      • Davis, California, Verenigde Staten, 95616
        • Sutter Davis Hospital
      • Duarte, California, Verenigde Staten, 91010
        • City of Hope Comprehensive Cancer Center
      • Dublin, California, Verenigde Staten, 94568
        • Kaiser Permanente Dublin
      • Dublin, California, Verenigde Staten, 94568
        • Epic Care-Dublin
      • Emeryville, California, Verenigde Staten, 94608
        • Bay Area Breast Surgeons Inc
      • Emeryville, California, Verenigde Staten, 94608
        • Epic Care Partners in Cancer Care
      • Fontana, California, Verenigde Staten, 92335
        • Kaiser Permanente-Fontana
      • Fremont, California, Verenigde Staten, 94538
        • Kaiser Permanente-Fremont
      • Fremont, California, Verenigde Staten, 94538
        • Palo Alto Medical Foundation-Fremont
      • Fresno, California, Verenigde Staten, 93720
        • Kaiser Permanente-Fresno
      • Fresno, California, Verenigde Staten, 93720
        • Fresno Cancer Center
      • Fullerton, California, Verenigde Staten, 92835
        • Saint Jude Medical Center
      • Greenbrae, California, Verenigde Staten, 94904
        • Marin Cancer Care Inc
      • Greenbrae, California, Verenigde Staten, 94904
        • Marin General Hospital
      • Harbor City, California, Verenigde Staten, 90710
        • Kaiser Permanente South Bay
      • Irvine, California, Verenigde Staten, 92618
        • Kaiser Permanente-Irvine
      • La Jolla, California, Verenigde Staten, 92093
        • UC San Diego Moores Cancer Center
      • Loma Linda, California, Verenigde Staten, 92354
        • Loma Linda University Medical Center
      • Los Angeles, California, Verenigde Staten, 90033
        • USC / Norris Comprehensive Cancer Center
      • Los Angeles, California, Verenigde Staten, 90048
        • Cedars-Sinai Medical Center
      • Los Angeles, California, Verenigde Staten, 90027
        • Kaiser Permanente Los Angeles Medical Center
      • Los Angeles, California, Verenigde Staten, 90034
        • Kaiser Permanente West Los Angeles
      • Los Angeles, California, Verenigde Staten, 90033
        • Los Angeles General Medical Center
      • Martinez, California, Verenigde Staten, 94553-3156
        • Contra Costa Regional Medical Center
      • Marysville, California, Verenigde Staten, 95901
        • Fremont - Rideout Cancer Center
      • Modesto, California, Verenigde Staten, 95355
        • Memorial Medical Center
      • Modesto, California, Verenigde Staten, 95356
        • Kaiser Permanente-Modesto
      • Monterey, California, Verenigde Staten, 93940
        • Community Hospital of Monterey Peninsula
      • Monterey, California, Verenigde Staten, 93940
        • Pacific Cancer Care-Monterey
      • Mountain View, California, Verenigde Staten, 94040
        • Palo Alto Medical Foundation-Camino Division
      • Mountain View, California, Verenigde Staten, 94040
        • Palo Alto Medical Foundation-Gynecologic Oncology
      • Newport Beach, California, Verenigde Staten, 92663
        • USC Norris Oncology/Hematology-Newport Beach
      • Novato, California, Verenigde Staten, 94945
        • Sutter Cancer Research Consortium
      • Oakland, California, Verenigde Staten, 94611
        • Kaiser Permanente-Oakland
      • Oakland, California, Verenigde Staten, 94611
        • Kaiser Permanente Oakland-Broadway
      • Oakland, California, Verenigde Staten, 94609
        • Alta Bates Summit Medical Center - Summit Campus
      • Oakland, California, Verenigde Staten, 94609
        • Bay Area Tumor Institute
      • Ontario, California, Verenigde Staten, 91761
        • Kaiser Permanente-Ontario
      • Orange, California, Verenigde Staten, 92868
        • UC Irvine Health/Chao Family Comprehensive Cancer Center
      • Orange, California, Verenigde Staten, 92868
        • Saint Joseph Hospital - Orange
      • Palm Springs, California, Verenigde Staten, 92262
        • Desert Regional Medical Center
      • Palo Alto, California, Verenigde Staten, 94304
        • VA Palo Alto Health Care System
      • Palo Alto, California, Verenigde Staten, 94304
        • Stanford Cancer Institute Palo Alto
      • Palo Alto, California, Verenigde Staten, 94301
        • Palo Alto Medical Foundation Health Care
      • Panorama City, California, Verenigde Staten, 91402
        • Kaiser Permanente - Panorama City
      • Pasadena, California, Verenigde Staten, 91105
        • Keck Medical Center of USC Pasadena
      • Rancho Cordova, California, Verenigde Staten, 95670
        • Kaiser Permanente-Rancho Cordova Cancer Center
      • Rancho Mirage, California, Verenigde Staten, 92270
        • Eisenhower Medical Center
      • Redwood City, California, Verenigde Staten, 94063
        • Kaiser Permanente-Redwood City
      • Redwood City, California, Verenigde Staten, 94063
        • Kaiser Permanente- Marshall Medical Offices
      • Richmond, California, Verenigde Staten, 94801
        • Kaiser Permanente-Richmond
      • Riverside, California, Verenigde Staten, 92505
        • Kaiser Permanente-Riverside
      • Rohnert Park, California, Verenigde Staten, 94928
        • Rohnert Park Cancer Center
      • Roseville, California, Verenigde Staten, 95678
        • The Permanente Medical Group-Roseville Radiation Oncology
      • Roseville, California, Verenigde Staten, 95661
        • Kaiser Permanente-Roseville
      • Roseville, California, Verenigde Staten, 95661
        • Sutter Cancer Centers Radiation Oncology Services-Roseville
      • Roseville, California, Verenigde Staten, 95661
        • Sutter Roseville Medical Center
      • Sacramento, California, Verenigde Staten, 95816
        • Sutter Medical Center Sacramento
      • Sacramento, California, Verenigde Staten, 95817
        • University of California Davis Comprehensive Cancer Center
      • Sacramento, California, Verenigde Staten, 95814
        • Kaiser Permanente Downtown Commons
      • Sacramento, California, Verenigde Staten, 95823
        • Kaiser Permanente-South Sacramento
      • Sacramento, California, Verenigde Staten, 95823
        • South Sacramento Cancer Center
      • Sacramento, California, Verenigde Staten, 95825
        • Kaiser Permanente Sacramento Medical Center
      • Sacramento, California, Verenigde Staten, 95816
        • Mercy Cancer Center - Sacramento
      • San Diego, California, Verenigde Staten, 92123
        • Rady Children's Hospital - San Diego
      • San Diego, California, Verenigde Staten, 92120
        • Kaiser Permanente-San Diego Zion
      • San Diego, California, Verenigde Staten, 92134
        • Naval Medical Center -San Diego
      • San Diego, California, Verenigde Staten, 92123
        • Sharp Memorial Hospital
      • San Diego, California, Verenigde Staten, 92103
        • UC San Diego Medical Center - Hillcrest
      • San Diego, California, Verenigde Staten, 92108
        • Kaiser Permanente-Rio San Diego
      • San Francisco, California, Verenigde Staten, 94115
        • Kaiser Permanente-San Francisco
      • San Francisco, California, Verenigde Staten, 94115
        • California Pacific Medical Center-Pacific Campus
      • San Jose, California, Verenigde Staten, 95119
        • Kaiser Permanente-Santa Teresa-San Jose
      • San Leandro, California, Verenigde Staten, 94577
        • Kaiser Permanente San Leandro
      • San Luis Obispo, California, Verenigde Staten, 93401
        • Pacific Central Coast Health Center-San Luis Obispo
      • San Marcos, California, Verenigde Staten, 92078
        • Kaiser Permanente-San Marcos
      • San Mateo, California, Verenigde Staten, 94401
        • Mills Health Center
      • San Rafael, California, Verenigde Staten, 94903
        • Kaiser San Rafael-Gallinas
      • San Rafael, California, Verenigde Staten, 94903
        • Kaiser Permanente-San Rafael
      • Santa Clara, California, Verenigde Staten, 95051
        • Kaiser Permanente Medical Center - Santa Clara
      • Santa Cruz, California, Verenigde Staten, 95065
        • Palo Alto Medical Foundation-Santa Cruz
      • Santa Maria, California, Verenigde Staten, 93444
        • Mission Hope Medical Oncology - Santa Maria
      • Santa Rosa, California, Verenigde Staten, 95403
        • Kaiser Permanente-Santa Rosa
      • Santa Rosa, California, Verenigde Staten, 95403
        • Sutter Pacific Medical Foundation
      • South San Francisco, California, Verenigde Staten, 94080
        • Kaiser Permanente Cancer Treatment Center
      • South San Francisco, California, Verenigde Staten, 94080
        • Kaiser Permanente-South San Francisco
      • St. Helena, California, Verenigde Staten, 94574
        • Saint Helena Hospital
      • Stockton, California, Verenigde Staten, 95210
        • Kaiser Permanente-Stockton
      • Stockton, California, Verenigde Staten, 95204
        • Saint Joseph's Medical Center
      • Sunnyvale, California, Verenigde Staten, 94086
        • Palo Alto Medical Foundation-Sunnyvale
      • Truckee, California, Verenigde Staten, 96161
        • Gene Upshaw Memorial Tahoe Forest Cancer Center
      • Upland, California, Verenigde Staten, 91786
        • City of Hope Upland
      • Vacaville, California, Verenigde Staten, 95688
        • Kaiser Permanente Medical Center-Vacaville
      • Vallejo, California, Verenigde Staten, 94589
        • Kaiser Permanente-Vallejo
      • Vallejo, California, Verenigde Staten, 94589
        • Sutter Solano Medical Center/Cancer Center
      • Walnut Creek, California, Verenigde Staten, 94596
        • Kaiser Permanente-Walnut Creek
      • Walnut Creek, California, Verenigde Staten, 94598
        • John Muir Medical Center-Walnut Creek
      • Walnut Creek, California, Verenigde Staten, 94597
        • Epic Care Cyberknife Center
      • West Covina, California, Verenigde Staten, 91790
        • City of Hope West Covina
      • Whittier, California, Verenigde Staten, 90602
        • Presbyterian Intercommunity Hospital
      • Woodland, California, Verenigde Staten, 95695
        • Woodland Memorial Hospital
      • Woodland Hills, California, Verenigde Staten, 91367
        • Kaiser Permanente-Woodland Hills
    • Colorado
      • Aurora, Colorado, Verenigde Staten, 80012
        • Rocky Mountain Cancer Centers-Aurora
      • Aurora, Colorado, Verenigde Staten, 80012
        • The Medical Center of Aurora
      • Aurora, Colorado, Verenigde Staten, 80045
        • UCHealth University of Colorado Hospital
      • Boulder, Colorado, Verenigde Staten, 80303
        • Boulder Community Foothills Hospital
      • Boulder, Colorado, Verenigde Staten, 80304
        • Rocky Mountain Cancer Centers-Boulder
      • Centennial, Colorado, Verenigde Staten, 80112
        • Rocky Mountain Cancer Centers - Centennial
      • Colorado Springs, Colorado, Verenigde Staten, 80907
        • Penrose-Saint Francis Healthcare
      • Colorado Springs, Colorado, Verenigde Staten, 80909
        • UCHealth Memorial Hospital Central
      • Colorado Springs, Colorado, Verenigde Staten, 80907
        • Rocky Mountain Cancer Centers-Penrose
      • Colorado Springs, Colorado, Verenigde Staten, 80920
        • Memorial Hospital North
      • Colorado Springs, Colorado, Verenigde Staten, 80923
        • Saint Francis Cancer Center
      • Denver, Colorado, Verenigde Staten, 80205
        • Kaiser Permanente-Franklin
      • Denver, Colorado, Verenigde Staten, 80218
        • Presbyterian - Saint Lukes Medical Center - Health One
      • Denver, Colorado, Verenigde Staten, 80220
        • Rose Medical Center
      • Denver, Colorado, Verenigde Staten, 80218
        • Rocky Mountain Cancer Centers-Midtown
      • Denver, Colorado, Verenigde Staten, 80220
        • Rocky Mountain Cancer Centers-Rose
      • Denver, Colorado, Verenigde Staten, 80204
        • Denver Health Medical Center
      • Denver, Colorado, Verenigde Staten, 80218
        • Colorado Blood Cancer Institute
      • Denver, Colorado, Verenigde Staten, 80204
        • Cancer Center of Colorado at Sloan's Lake
      • Denver, Colorado, Verenigde Staten, 80209
        • The Women's Imaging Center
      • Denver, Colorado, Verenigde Staten, 80206
        • National Jewish Health-Main Campus
      • Denver, Colorado, Verenigde Staten, 80218
        • Saint Joseph Hospital - Cancer Centers of Colorado
      • Denver, Colorado, Verenigde Staten, 80210
        • AdventHealth Porter
      • Durango, Colorado, Verenigde Staten, 81301
        • Mercy Medical Center
      • Durango, Colorado, Verenigde Staten, 81301
        • CommonSpirit Cancer Center Mercy
      • Englewood, Colorado, Verenigde Staten, 80113
        • Mountain Blue Cancer Care Center - Swedish
      • Englewood, Colorado, Verenigde Staten, 80113
        • Swedish Medical Center
      • Englewood, Colorado, Verenigde Staten, 80113
        • Rocky Mountain Cancer Centers - Swedish
      • Fort Collins, Colorado, Verenigde Staten, 80524
        • Poudre Valley Hospital
      • Golden, Colorado, Verenigde Staten, 80401
        • Mountain Blue Cancer Care Center
      • Golden, Colorado, Verenigde Staten, 80401
        • National Jewish Health-Western Hematology Oncology
      • Grand Junction, Colorado, Verenigde Staten, 81501
        • Saint Mary's Hospital and Regional Medical Center
      • Grand Junction, Colorado, Verenigde Staten, 81505
        • Grand Valley Oncology
      • Greeley, Colorado, Verenigde Staten, 80631
        • Banner North Colorado Medical Center
      • Greenwood Village, Colorado, Verenigde Staten, 80111
        • Rocky Mountain Cancer Centers-Greenwood Village
      • Lafayette, Colorado, Verenigde Staten, 80026
        • Kaiser Permanente-Rock Creek
      • Lafayette, Colorado, Verenigde Staten, 80026
        • Good Samaritan Hospital - Cancer Centers of Colorado
      • Lakewood, Colorado, Verenigde Staten, 80228
        • Rocky Mountain Cancer Centers-Lakewood
      • Lakewood, Colorado, Verenigde Staten, 80228
        • CommonSpirit Saint Anthony Hospital Cancer Center
      • Littleton, Colorado, Verenigde Staten, 80120
        • Rocky Mountain Cancer Centers-Littleton
      • Littleton, Colorado, Verenigde Staten, 80122
        • AdventHealth Littleton
      • Lone Tree, Colorado, Verenigde Staten, 80124
        • Kaiser Permanente-Lone Tree
      • Lone Tree, Colorado, Verenigde Staten, 80124
        • Sky Ridge Medical Center
      • Lone Tree, Colorado, Verenigde Staten, 80124
        • Rocky Mountain Cancer Centers-Sky Ridge
      • Longmont, Colorado, Verenigde Staten, 80501
        • Longmont United Hospital
      • Longmont, Colorado, Verenigde Staten, 80501
        • Rocky Mountain Cancer Centers-Longmont
      • Loveland, Colorado, Verenigde Staten, 80539
        • Banner North Colorado Medical Center - Loveland Campus
      • Parker, Colorado, Verenigde Staten, 80138
        • Rocky Mountain Cancer Centers-Parker
      • Parker, Colorado, Verenigde Staten, 80138
        • AdventHealth Parker
      • Pueblo, Colorado, Verenigde Staten, 81004
        • Saint Mary Corwin Medical Center
      • Pueblo, Colorado, Verenigde Staten, 81008
        • Rocky Mountain Cancer Centers - Pueblo
      • Thornton, Colorado, Verenigde Staten, 80260
        • Rocky Mountain Cancer Centers-Thornton
      • Thornton, Colorado, Verenigde Staten, 80260
        • National Jewish Health-Northern Hematology Oncology
      • Wheat Ridge, Colorado, Verenigde Staten, 80401
        • Intermountain Health Lutheran Hospital
    • Connecticut
      • Derby, Connecticut, Verenigde Staten, 06418
        • Smilow Cancer Hospital-Derby Care Center
      • Fairfield, Connecticut, Verenigde Staten, 06824
        • Smilow Cancer Hospital Care Center-Fairfield
      • Glastonbury, Connecticut, Verenigde Staten, 06033
        • Smilow Cancer Hospital Care Center at Glastonbury
      • Greenwich, Connecticut, Verenigde Staten, 06830
        • Smilow Cancer Hospital Care Center at Greenwich
      • Guilford, Connecticut, Verenigde Staten, 06437
        • Smilow Cancer Hospital Care Center - Guilford
      • Hartford, Connecticut, Verenigde Staten, 06105
        • Smilow Cancer Hospital Care Center at Saint Francis
      • New Haven, Connecticut, Verenigde Staten, 06520
        • Yale University
      • New Haven, Connecticut, Verenigde Staten, 06510
        • Smilow Cancer Center/Yale-New Haven Hospital
      • North Haven, Connecticut, Verenigde Staten, 06473
        • Yale-New Haven Hospital North Haven Medical Center
      • Norwich, Connecticut, Verenigde Staten, 06360
        • Eastern Connecticut Hematology and Oncology Associates
      • Orange, Connecticut, Verenigde Staten, 06477
        • Smilow Cancer Hospital-Orange Care Center
      • Stamford, Connecticut, Verenigde Staten, 06904
        • Stamford Hospital/Bennett Cancer Center
      • Torrington, Connecticut, Verenigde Staten, 06790
        • Smilow Cancer Hospital-Torrington Care Center
      • Trumbull, Connecticut, Verenigde Staten, 06611
        • Smilow Cancer Hospital Care Center-Trumbull
      • Waterbury, Connecticut, Verenigde Staten, 06708
        • Smilow Cancer Hospital-Waterbury Care Center
      • Waterford, Connecticut, Verenigde Staten, 06385
        • Smilow Cancer Hospital Care Center - Waterford
      • West Haven, Connecticut, Verenigde Staten, 06516
        • Veterans Affairs Connecticut Healthcare System-West Haven Campus
    • Delaware
      • Lewes, Delaware, Verenigde Staten, 19958
        • Beebe Medical Center
      • Millville, Delaware, Verenigde Staten, 19967
        • Beebe South Coastal Health Campus
      • Newark, Delaware, Verenigde Staten, 19713
        • Helen F Graham Cancer Center
      • Newark, Delaware, Verenigde Staten, 19713
        • Delaware Clinical and Laboratory Physicians PA
      • Newark, Delaware, Verenigde Staten, 19713
        • Medical Oncology Hematology Consultants PA
      • Newark, Delaware, Verenigde Staten, 19718
        • Christiana Care Health System-Christiana Hospital
      • Rehoboth Beach, Delaware, Verenigde Staten, 19971
        • Beebe Health Campus
      • Seaford, Delaware, Verenigde Staten, 19973
        • TidalHealth Nanticoke / Allen Cancer Center
      • Wilmington, Delaware, Verenigde Staten, 19801
        • Christiana Care Health System-Wilmington Hospital
    • District of Columbia
      • Washington D.C., District of Columbia, Verenigde Staten, 20010
        • MedStar Washington Hospital Center
      • Washington D.C., District of Columbia, Verenigde Staten, 20007
        • MedStar Georgetown University Hospital
      • Washington D.C., District of Columbia, Verenigde Staten, 20016
        • Sibley Memorial Hospital
    • Florida
      • Aventura, Florida, Verenigde Staten, 33180
        • Mount Sinai Comprehensive Cancer Center at Aventura
      • Coral Gables, Florida, Verenigde Staten, 33146
        • UM Sylvester Comprehensive Cancer Center at Coral Gables
      • Coral Springs, Florida, Verenigde Staten, 33065
        • UM Sylvester Comprehensive Cancer Center at Coral Springs
      • Deerfield Beach, Florida, Verenigde Staten, 33442
        • UM Sylvester Comprehensive Cancer Center at Deerfield Beach
      • Deerfield Beach, Florida, Verenigde Staten, 33064
        • Broward Health North
      • Fort Lauderdale, Florida, Verenigde Staten, 33316
        • Broward Health Medical Center
      • Fort Lauderdale, Florida, Verenigde Staten, 33308
        • Holy Cross Hospital
      • Gainesville, Florida, Verenigde Staten, 32610
        • UF Health Cancer Institute - Gainesville
      • Hollywood, Florida, Verenigde Staten, 33021
        • Memorial Regional Hospital/Joe DiMaggio Children's Hospital
      • Hollywood, Florida, Verenigde Staten, 33021
        • UM Sylvester Comprehensive Cancer Center at Hollywood
      • Jacksonville, Florida, Verenigde Staten, 32224-9980
        • Mayo Clinic in Florida
      • Lakeland, Florida, Verenigde Staten, 33805
        • The Watson Clinic
      • Miami, Florida, Verenigde Staten, 33136
        • University of Miami Miller School of Medicine-Sylvester Cancer Center
      • Miami, Florida, Verenigde Staten, 33176
        • Miami Cancer Institute
      • Miami, Florida, Verenigde Staten, 33176
        • UM Sylvester Comprehensive Cancer Center at Kendall
      • Miami Beach, Florida, Verenigde Staten, 33140
        • Mount Sinai Medical Center
      • Ocoee, Florida, Verenigde Staten, 34761
        • Health Central
      • Orlando, Florida, Verenigde Staten, 32806
        • Orlando Health Cancer Institute
      • Pembroke Pines, Florida, Verenigde Staten, 33028
        • Memorial Hospital West
      • Plantation, Florida, Verenigde Staten, 33324
        • UM Sylvester Comprehensive Cancer Center at Plantation
      • Tampa, Florida, Verenigde Staten, 33612
        • Moffitt Cancer Center
      • Tampa, Florida, Verenigde Staten, 33607
        • Saint Joseph's Hospital/Children's Hospital-Tampa
      • Vero Beach, Florida, Verenigde Staten, 32960
        • Indian River Medical Center
    • Georgia
      • Athens, Georgia, Verenigde Staten, 30607
        • University Cancer and Blood Center LLC
      • Atlanta, Georgia, Verenigde Staten, 30308
        • Emory University Hospital Midtown
      • Atlanta, Georgia, Verenigde Staten, 30322
        • Emory University Hospital/Winship Cancer Institute
      • Atlanta, Georgia, Verenigde Staten, 30342
        • Emory Saint Joseph's Hospital
      • Atlanta, Georgia, Verenigde Staten, 30309
        • Piedmont Hospital
      • Atlanta, Georgia, Verenigde Staten, 30342
        • Northside Hospital
      • Augusta, Georgia, Verenigde Staten, 30912
        • Augusta University Medical Center
      • Braselton, Georgia, Verenigde Staten, 30517
        • Northeast Georgia Medical Center Braselton
      • Columbus, Georgia, Verenigde Staten, 31904
        • John B Amos Cancer Center
      • Cumming, Georgia, Verenigde Staten, 30041
        • Northside Hospital-Forsyth
      • Decatur, Georgia, Verenigde Staten, 30033
        • Emory Decatur Hospital
      • Duluth, Georgia, Verenigde Staten, 30096
        • Northside Hospital - Duluth
      • Gainesville, Georgia, Verenigde Staten, 30501
        • Northeast Georgia Medical Center-Gainesville
      • Gainesville, Georgia, Verenigde Staten, 30501
        • The Longstreet Clinic - Gainesville
      • Lawrenceville, Georgia, Verenigde Staten, 30046
        • Northside Hospital - Gwinnett
      • Macon, Georgia, Verenigde Staten, 31201
        • Central Georgia Gynecologic Oncology
      • Macon, Georgia, Verenigde Staten, 31201
        • Atrium Health Navicent
      • Newnan, Georgia, Verenigde Staten, 30265
        • CTCA at Southeastern Regional Medical Center
      • Rome, Georgia, Verenigde Staten, 30165
        • Harbin Clinic Medical Oncology and Clinical Research
      • Savannah, Georgia, Verenigde Staten, 31405
        • Lewis Cancer and Research Pavilion at Saint Joseph's/Candler
      • Savannah, Georgia, Verenigde Staten, 31404
        • Memorial Health University Medical Center
      • Savannah, Georgia, Verenigde Staten, 31404
        • Summit Cancer Care-Memorial
      • Savannah, Georgia, Verenigde Staten, 31405
        • Summit Cancer Care-Candler
      • Savannah, Georgia, Verenigde Staten, 31404
        • Low Country Cancer Care
      • Snellville, Georgia, Verenigde Staten, 30078
        • Suburban Hematology Oncology Associates - Snellville
      • Thomasville, Georgia, Verenigde Staten, 31792
        • Lewis Hall Singletary Oncology Center
      • Valdosta, Georgia, Verenigde Staten, 31602
        • South Georgia Medical Center/Pearlman Cancer Center
    • Hawaii
      • Honolulu, Hawaii, Verenigde Staten, 96813
        • Queen's Medical Center
      • Honolulu, Hawaii, Verenigde Staten, 96817
        • The Cancer Center of Hawaii-Liliha
      • Honolulu, Hawaii, Verenigde Staten, 96813
        • Hawaii Cancer Care Inc - Waterfront Plaza
      • Honolulu, Hawaii, Verenigde Staten, 96813
        • Queen's Cancer Cenrer - POB I
      • Honolulu, Hawaii, Verenigde Staten, 96813
        • Straub Clinic and Hospital
      • Honolulu, Hawaii, Verenigde Staten, 96813
        • University of Hawaii Cancer Center
      • Honolulu, Hawaii, Verenigde Staten, 96817
        • Hawaii Cancer Care Inc-Liliha
      • Honolulu, Hawaii, Verenigde Staten, 96817
        • Kuakini Medical Center
      • Honolulu, Hawaii, Verenigde Staten, 96817
        • Queen's Cancer Center - Kuakini
      • Honolulu, Hawaii, Verenigde Staten, 96826
        • Kapiolani Medical Center for Women and Children
      • Honolulu, Hawaii, Verenigde Staten, 96813
        • Island Urology
      • Honolulu, Hawaii, Verenigde Staten, 96819
        • Kaiser Permanente Moanalua Medical Center
      • Honolulu, Hawaii, Verenigde Staten, 96817
        • Hawaii Diagnostic Radiology Services LLC
      • Kahului, Hawaii, Verenigde Staten, 96732
        • Straub Medical Center - Kahului Clinic
      • Kailua, Hawaii, Verenigde Staten, 96734
        • Castle Medical Center
      • Lihue, Hawaii, Verenigde Staten, 96766
        • Wilcox Memorial Hospital and Kauai Medical Clinic
      • ‘Aiea, Hawaii, Verenigde Staten, 96701
        • Hawaii Cancer Care - Westridge
      • ‘Aiea, Hawaii, Verenigde Staten, 96701
        • Pali Momi Medical Center
      • ‘Aiea, Hawaii, Verenigde Staten, 96701
        • Queen's Cancer Center - Pearlridge
      • ‘Aiea, Hawaii, Verenigde Staten, 96701
        • The Cancer Center of Hawaii-Pali Momi
      • ‘Aiea, Hawaii, Verenigde Staten, 96701
        • Straub Pearlridge Clinic
      • ‘Ewa Beach, Hawaii, Verenigde Staten, 96706
        • The Queen's Medical Center - West Oahu
    • Idaho
      • Boise, Idaho, Verenigde Staten, 83706
        • Saint Alphonsus Cancer Care Center-Boise
      • Boise, Idaho, Verenigde Staten, 83712
        • Saint Luke's Cancer Institute - Boise
      • Caldwell, Idaho, Verenigde Staten, 83605
        • Saint Alphonsus Cancer Care Center-Caldwell
      • Coeur d'Alene, Idaho, Verenigde Staten, 83814
        • Kootenai Health - Coeur d'Alene
      • Emmett, Idaho, Verenigde Staten, 83617
        • Walter Knox Memorial Hospital
      • Fruitland, Idaho, Verenigde Staten, 83619
        • Saint Luke's Cancer Institute - Fruitland
      • Meridian, Idaho, Verenigde Staten, 83642
        • Idaho Urologic Institute-Meridian
      • Meridian, Idaho, Verenigde Staten, 83642
        • Saint Luke's Cancer Institute - Meridian
      • Nampa, Idaho, Verenigde Staten, 83687
        • Saint Alphonsus Cancer Care Center-Nampa
      • Nampa, Idaho, Verenigde Staten, 83687
        • Saint Luke's Cancer Institute - Nampa
      • Post Falls, Idaho, Verenigde Staten, 83854
        • Kootenai Clinic Cancer Services - Post Falls
      • Sandpoint, Idaho, Verenigde Staten, 83864
        • Kootenai Clinic Cancer Services - Sandpoint
      • Twin Falls, Idaho, Verenigde Staten, 83301
        • Saint Luke's Cancer Institute - Twin Falls
    • Illinois
      • Alton, Illinois, Verenigde Staten, 62002
        • OSF Saint Anthony's Health Center
      • Aurora, Illinois, Verenigde Staten, 60504
        • Rush-Copley Medical Center
      • Bloomington, Illinois, Verenigde Staten, 61704
        • Illinois CancerCare-Bloomington
      • Bloomington, Illinois, Verenigde Staten, 61701
        • OSF Saint Joseph Medical Center
      • Canton, Illinois, Verenigde Staten, 61520
        • Illinois CancerCare-Canton
      • Carbondale, Illinois, Verenigde Staten, 62902
        • Memorial Hospital of Carbondale
      • Carterville, Illinois, Verenigde Staten, 62918
        • SIH Cancer Institute
      • Carthage, Illinois, Verenigde Staten, 62321
        • Illinois CancerCare-Carthage
      • Centralia, Illinois, Verenigde Staten, 62801
        • Centralia Oncology Clinic
      • Chicago, Illinois, Verenigde Staten, 60611
        • Northwestern University
      • Chicago, Illinois, Verenigde Staten, 60637
        • University of Chicago Comprehensive Cancer Center
      • Chicago, Illinois, Verenigde Staten, 60612
        • University of Illinois
      • Chicago, Illinois, Verenigde Staten, 60612
        • John H Stroger Jr Hospital of Cook County
      • Chicago, Illinois, Verenigde Staten, 60608
        • Mount Sinai Hospital Medical Center
      • Chicago, Illinois, Verenigde Staten, 60625
        • Swedish Covenant Hospital
      • Chicago, Illinois, Verenigde Staten, 60657
        • Advocate Illinois Masonic Medical Center
      • Chicago, Illinois, Verenigde Staten, 60612
        • Rush MD Anderson Cancer Center
      • Crystal Lake, Illinois, Verenigde Staten, 60014
        • AMG Crystal Lake - Oncology
      • Danville, Illinois, Verenigde Staten, 61832
        • Carle at The Riverfront
      • DeKalb, Illinois, Verenigde Staten, 60115
        • Northwestern Medicine Cancer Center Kishwaukee
      • Decatur, Illinois, Verenigde Staten, 62526
        • Decatur Memorial Hospital
      • Decatur, Illinois, Verenigde Staten, 62526
        • Cancer Care Specialists of Illinois - Decatur
      • Dixon, Illinois, Verenigde Staten, 61021
        • Illinois CancerCare-Dixon
      • Effingham, Illinois, Verenigde Staten, 62401
        • Crossroads Cancer Center
      • Effingham, Illinois, Verenigde Staten, 62401
        • Carle Physician Group-Effingham
      • Elk Grove Village, Illinois, Verenigde Staten, 60007
        • Ascension Alexian Brothers - Elk Grove Village
      • Elmhurst, Illinois, Verenigde Staten, 60126
        • Elmhurst Memorial Hospital
      • Eureka, Illinois, Verenigde Staten, 61530
        • Illinois CancerCare-Eureka
      • Evanston, Illinois, Verenigde Staten, 60201
        • NorthShore University HealthSystem-Evanston Hospital
      • Evanston, Illinois, Verenigde Staten, 60202
        • Saint Francis Hospital
      • Galesburg, Illinois, Verenigde Staten, 61401
        • Western Illinois Cancer Treatment Center
      • Galesburg, Illinois, Verenigde Staten, 61401
        • Illinois CancerCare-Galesburg
      • Geneva, Illinois, Verenigde Staten, 60134
        • Northwestern Medicine Cancer Center Delnor
      • Glenview, Illinois, Verenigde Staten, 60026
        • NorthShore University HealthSystem-Glenbrook Hospital
      • Harvey, Illinois, Verenigde Staten, 60426
        • Ingalls Memorial Hospital
      • Highland Park, Illinois, Verenigde Staten, 60035
        • NorthShore University HealthSystem-Highland Park Hospital
      • Joliet, Illinois, Verenigde Staten, 60435
        • Duly Health and Care Joliet
      • Kankakee, Illinois, Verenigde Staten, 60901
        • Presence Saint Mary's Hospital
      • Kewanee, Illinois, Verenigde Staten, 61443
        • Illinois CancerCare-Kewanee Clinic
      • Lake Forest, Illinois, Verenigde Staten, 60045
        • Northwestern Medicine Lake Forest Hospital
      • Libertyville, Illinois, Verenigde Staten, 60048
        • AMG Libertyville - Oncology
      • Macomb, Illinois, Verenigde Staten, 61455
        • Illinois CancerCare-Macomb
      • Mattoon, Illinois, Verenigde Staten, 61938
        • Carle Physician Group-Mattoon/Charleston
      • Maywood, Illinois, Verenigde Staten, 60153
        • Loyola University Medical Center
      • Melrose Park, Illinois, Verenigde Staten, 60160
        • Marjorie Weinberg Cancer Center at Loyola-Gottlieb
      • Moline, Illinois, Verenigde Staten, 61265
        • Trinity Medical Center
      • Mount Vernon, Illinois, Verenigde Staten, 62864
        • SSM Health Good Samaritan
      • Naperville, Illinois, Verenigde Staten, 60540
        • Edward Hospital/Cancer Center
      • New Lenox, Illinois, Verenigde Staten, 60451
        • UC Comprehensive Cancer Center at Silver Cross
      • O'Fallon, Illinois, Verenigde Staten, 62269
        • Cancer Care Center of O'Fallon
      • Orland Park, Illinois, Verenigde Staten, 60462
        • University of Chicago Medicine-Orland Park
      • Ottawa, Illinois, Verenigde Staten, 61350
        • Illinois CancerCare-Ottawa Clinic
      • Ottawa, Illinois, Verenigde Staten, 61350
        • Radiation Oncology of Northern Illinois
      • Pekin, Illinois, Verenigde Staten, 61554
        • Illinois CancerCare-Pekin
      • Pekin, Illinois, Verenigde Staten, 61554
        • OSF Saint Francis Radiation Oncology at Pekin
      • Peoria, Illinois, Verenigde Staten, 61636
        • Methodist Medical Center of Illinois
      • Peoria, Illinois, Verenigde Staten, 61637
        • OSF Saint Francis Medical Center
      • Peoria, Illinois, Verenigde Staten, 61615
        • Illinois CancerCare-Peoria
      • Peoria, Illinois, Verenigde Staten, 61615
        • OSF Saint Francis Radiation Oncology at Peoria Cancer Center
      • Peru, Illinois, Verenigde Staten, 61354
        • Illinois CancerCare-Peru
      • Peru, Illinois, Verenigde Staten, 61354
        • Valley Radiation Oncology
      • Plainfield, Illinois, Verenigde Staten, 60585
        • Edward Hospital/Cancer Center?Plainfield
      • Princeton, Illinois, Verenigde Staten, 61356
        • Illinois CancerCare-Princeton
      • Skokie, Illinois, Verenigde Staten, 60076
        • Hematology Oncology Associates of Illinois - Skokie
      • Skokie, Illinois, Verenigde Staten, 60076
        • North Shore Medical Center
      • Springfield, Illinois, Verenigde Staten, 62702
        • Southern Illinois University School of Medicine
      • Springfield, Illinois, Verenigde Staten, 62702
        • Springfield Clinic
      • Springfield, Illinois, Verenigde Staten, 62702
        • Central Illinois Hematology Oncology Center
      • Springfield, Illinois, Verenigde Staten, 62781
        • Springfield Memorial Hospital
      • Swansea, Illinois, Verenigde Staten, 62226
        • Southwest Illinois Health Services LLP
      • Urbana, Illinois, Verenigde Staten, 61801
        • Carle Cancer Center
      • Urbana, Illinois, Verenigde Staten, 61801
        • The Carle Foundation Hospital
      • Warrenville, Illinois, Verenigde Staten, 60555
        • Northwestern Medicine Cancer Center Warrenville
      • Washington, Illinois, Verenigde Staten, 61571
        • Illinois CancerCare - Washington
      • Yorkville, Illinois, Verenigde Staten, 60560
        • Rush-Copley Healthcare Center
      • Zion, Illinois, Verenigde Staten, 60099
        • Midwestern Regional Medical Center
    • Indiana
      • Crown Point, Indiana, Verenigde Staten, 46307
        • Michiana Hematology Oncology PC-Crown Point
      • Elkhart, Indiana, Verenigde Staten, 46514
        • Michiana Hematology Oncology PC-Elkhart
      • Evansville, Indiana, Verenigde Staten, 47713
        • Deaconess Clinic Downtown
      • Indianapolis, Indiana, Verenigde Staten, 46202
        • Indiana University/Melvin and Bren Simon Cancer Center
      • Indianapolis, Indiana, Verenigde Staten, 46219
        • Community Cancer Center East
      • Indianapolis, Indiana, Verenigde Staten, 46227
        • Community Cancer Center South
      • Indianapolis, Indiana, Verenigde Staten, 46256
        • Community Cancer Center North
      • Indianapolis, Indiana, Verenigde Staten, 46202
        • Sidney and Lois Eskenazi Hospital
      • Indianapolis, Indiana, Verenigde Staten, 46290
        • Springmill Medical Center
      • Kokomo, Indiana, Verenigde Staten, 46904
        • Community Howard Regional Health
      • Lafayette, Indiana, Verenigde Staten, 47904
        • IU Health Arnett Cancer Care
      • Michigan City, Indiana, Verenigde Staten, 46360
        • Franciscan Saint Anthony Health-Michigan City
      • Michigan City, Indiana, Verenigde Staten, 46360
        • Woodland Cancer Care Center
      • Mishawaka, Indiana, Verenigde Staten, 46545
        • Memorial Regional Cancer Center Day Road
      • Mishawaka, Indiana, Verenigde Staten, 46545
        • Michiana Hematology Oncology PC-Mishawaka
      • New Albany, Indiana, Verenigde Staten, 47150
        • Baptist Health Floyd
      • Newburgh, Indiana, Verenigde Staten, 47630
        • Chancellor Center for Oncology
      • Plymouth, Indiana, Verenigde Staten, 46563
        • Michiana Hematology Oncology PC-Plymouth
      • Richmond, Indiana, Verenigde Staten, 47374
        • Reid Health
      • South Bend, Indiana, Verenigde Staten, 46601
        • Memorial Hospital of South Bend
      • Westville, Indiana, Verenigde Staten, 46391
        • Michiana Hematology Oncology PC-Westville
    • Iowa
      • Ames, Iowa, Verenigde Staten, 50010
        • Mary Greeley Medical Center
      • Ames, Iowa, Verenigde Staten, 50010
        • McFarland Clinic - Ames
      • Boone, Iowa, Verenigde Staten, 50036
        • McFarland Clinic - Boone
      • Carroll, Iowa, Verenigde Staten, 51401
        • Saint Anthony Regional Hospital
      • Cedar Rapids, Iowa, Verenigde Staten, 52403
        • Mercy Hospital
      • Cedar Rapids, Iowa, Verenigde Staten, 52403
        • Oncology Associates at Mercy Medical Center
      • Cedar Rapids, Iowa, Verenigde Staten, 52402
        • Physicians' Clinic of Iowa PC
      • Clive, Iowa, Verenigde Staten, 50325
        • Mercy Cancer Center-West Lakes
      • Clive, Iowa, Verenigde Staten, 50325
        • UI Health Care Mission Cancer and Blood - West Des Moines Clinic
      • Council Bluffs, Iowa, Verenigde Staten, 51503
        • Alegent Health Mercy Hospital
      • Council Bluffs, Iowa, Verenigde Staten, 51503
        • Heartland Oncology and Hematology LLP
      • Council Bluffs, Iowa, Verenigde Staten, 51503
        • Methodist Jennie Edmundson Hospital
      • Creston, Iowa, Verenigde Staten, 50801
        • Greater Regional Medical Center
      • Des Moines, Iowa, Verenigde Staten, 50309
        • Iowa Methodist Medical Center
      • Des Moines, Iowa, Verenigde Staten, 50314
        • Mercy Medical Center - Des Moines
      • Des Moines, Iowa, Verenigde Staten, 50314
        • Broadlawns Medical Center
      • Des Moines, Iowa, Verenigde Staten, 50316
        • Iowa Lutheran Hospital
      • Des Moines, Iowa, Verenigde Staten, 50309
        • UI Health Care Mission Cancer and Blood - Des Moines Clinic
      • Des Moines, Iowa, Verenigde Staten, 50314
        • UI Health Care Mission Cancer and Blood - Laurel Clinic
      • Fairfield, Iowa, Verenigde Staten, 52556
        • JCHC McCreery Cancer Center
      • Fort Dodge, Iowa, Verenigde Staten, 50501
        • McFarland Clinic - Trinity Cancer Center
      • Fort Dodge, Iowa, Verenigde Staten, 50501
        • UI Healthcare Mission Cancer and Blood - Fort Dodge
      • Jefferson, Iowa, Verenigde Staten, 50129
        • McFarland Clinic - Jefferson
      • Marshalltown, Iowa, Verenigde Staten, 50158
        • McFarland Clinic - Marshalltown
      • Ottumwa, Iowa, Verenigde Staten, 52501
        • Ottumwa Regional Health Center
      • Sioux City, Iowa, Verenigde Staten, 51101
        • Siouxland Regional Cancer Center
      • West Des Moines, Iowa, Verenigde Staten, 50266-7700
        • Methodist West Hospital
      • West Des Moines, Iowa, Verenigde Staten, 50266
        • Mercy Medical Center-West Lakes
    • Kansas
      • Coffeyville, Kansas, Verenigde Staten, 67337
        • Coffeyville Regional Medical Center
      • Emporia, Kansas, Verenigde Staten, 66801
        • Newman Regional Health
      • Fairway, Kansas, Verenigde Staten, 66205
        • University of Kansas Clinical Research Center
      • Garden City, Kansas, Verenigde Staten, 67846
        • Central Care Cancer Center - Garden City
      • Garden City, Kansas, Verenigde Staten, 67846
        • Saint Catherine Hospital
      • Great Bend, Kansas, Verenigde Staten, 67530
        • Central Care Cancer Center - Great Bend
      • Great Bend, Kansas, Verenigde Staten, 67530
        • Saint Rose Ambulatory and Surgery Center
      • Hays, Kansas, Verenigde Staten, 67601
        • HaysMed
      • Kansas City, Kansas, Verenigde Staten, 66160
        • University of Kansas Cancer Center
      • Kansas City, Kansas, Verenigde Staten, 66112
        • University of Kansas Cancer Center-West
      • Lawrence, Kansas, Verenigde Staten, 66044
        • Lawrence Memorial Hospital
      • Lenexa, Kansas, Verenigde Staten, 66219
        • Kansas Institute of Medicine Cancer and Blood Center
      • Lenexa, Kansas, Verenigde Staten, 66219
        • Minimally Invasive Surgery Hospital
      • Olathe, Kansas, Verenigde Staten, 66061
        • The University of Kansas Cancer Center - Olathe
      • Overland Park, Kansas, Verenigde Staten, 66210
        • University of Kansas Cancer Center-Overland Park
      • Overland Park, Kansas, Verenigde Staten, 66209
        • Menorah Medical Center
      • Overland Park, Kansas, Verenigde Staten, 66213
        • Saint Luke's South Hospital
      • Pittsburg, Kansas, Verenigde Staten, 66762
        • Mercy Hospital Pittsburg
      • Salina, Kansas, Verenigde Staten, 67401
        • Salina Regional Health Center
      • Topeka, Kansas, Verenigde Staten, 66606
        • University of Kansas Health System Saint Francis Campus
      • Westwood, Kansas, Verenigde Staten, 66205
        • University of Kansas Hospital-Westwood Cancer Center
    • Kentucky
      • Bardstown, Kentucky, Verenigde Staten, 40004
        • CommonSpirit Saint Joseph Hospital - Bardstown
      • Corbin, Kentucky, Verenigde Staten, 40701
        • Baptist Health Corbin
      • Corbin, Kentucky, Verenigde Staten, 40701
        • Commonwealth Cancer Center-Corbin
      • Crestview Hills, Kentucky, Verenigde Staten, 41017
        • Oncology Hematology Care Inc-Crestview
      • Edgewood, Kentucky, Verenigde Staten, 41017
        • Saint Elizabeth Healthcare Edgewood
      • Elizabethtown, Kentucky, Verenigde Staten, 42701
        • Baptist Health Hardin
      • Fort Thomas, Kentucky, Verenigde Staten, 41075
        • Saint Elizabeth Healthcare Fort Thomas
      • Lexington, Kentucky, Verenigde Staten, 40536
        • University of Kentucky/Markey Cancer Center
      • Lexington, Kentucky, Verenigde Staten, 40504
        • Saint Joseph Radiation Oncology Resource Center
      • Lexington, Kentucky, Verenigde Staten, 40503
        • Baptist Health Lexington
      • Lexington, Kentucky, Verenigde Staten, 40509
        • CommonSpirit Saint Joseph Medical Center - East Lexington
      • London, Kentucky, Verenigde Staten, 40741
        • CommonSpirit Saint Joseph Hospital London
      • Louisville, Kentucky, Verenigde Staten, 40202
        • The James Graham Brown Cancer Center at University of Louisville
      • Louisville, Kentucky, Verenigde Staten, 40202
        • Jewish Hospital
      • Louisville, Kentucky, Verenigde Staten, 40245
        • UofL Health Medical Center Northeast
      • Louisville, Kentucky, Verenigde Staten, 40207
        • Baptist Health Louisville
      • Louisville, Kentucky, Verenigde Staten, 40215
        • Saints Mary and Elizabeth Hospital
      • Madisonville, Kentucky, Verenigde Staten, 42431
        • Baptist Health Madisonville/Merle Mahr Cancer Center
      • Paducah, Kentucky, Verenigde Staten, 42003
        • Baptist Health Paducah
      • Shepherdsville, Kentucky, Verenigde Staten, 40165
        • Jewish Hospital Medical Center South
    • Louisiana
      • Baton Rouge, Louisiana, Verenigde Staten, 70805
        • LSU Health Baton Rouge-North Clinic
      • Baton Rouge, Louisiana, Verenigde Staten, 70809
        • Louisiana Hematology Oncology Associates LLC
      • Baton Rouge, Louisiana, Verenigde Staten, 70809
        • Mary Bird Perkins Cancer Center
      • Baton Rouge, Louisiana, Verenigde Staten, 70809
        • Ochsner Health Center-Summa
      • Baton Rouge, Louisiana, Verenigde Staten, 70816
        • Medical Center of Baton Rouge
      • Baton Rouge, Louisiana, Verenigde Staten, 70836
        • Ochsner High Grove
      • Baton Rouge, Louisiana, Verenigde Staten, 70806
        • Baton Rouge General Medical Center
      • Baton Rouge, Louisiana, Verenigde Staten, 70809
        • Hematology/Oncology Clinic PLLC
      • Baton Rouge, Louisiana, Verenigde Staten, 70808
        • Our Lady of The Lake
      • Baton Rouge, Louisiana, Verenigde Staten, 70817
        • Our Lady of the Lake Medical Oncology
      • Baton Rouge, Louisiana, Verenigde Staten, 70810
        • The NeuroMedical Center-Clinic
      • Baton Rouge, Louisiana, Verenigde Staten, 70808
        • Our Lady of the Lake Physician Group
      • Covington, Louisiana, Verenigde Staten, 70433
        • Mary Bird Perkins Cancer Center - Covington
      • Covington, Louisiana, Verenigde Staten, 70433
        • Northshore Oncology Associates-Covington
      • Covington, Louisiana, Verenigde Staten, 70433
        • Ochsner Hematology Oncology North Shore - Covington (West Region)
      • Covington, Louisiana, Verenigde Staten, 70433
        • Women's Cancer Care-Covington
      • Gretna, Louisiana, Verenigde Staten, 70056
        • Ochsner Medical Center West Bank
      • Houma, Louisiana, Verenigde Staten, 70360
        • Mary Bird Perkins Cancer Center - Houma
      • Houma, Louisiana, Verenigde Staten, 70360
        • Terrebonne General Medical Center
      • Houma, Louisiana, Verenigde Staten, 70360
        • Oncology Center of The South Incorporated
      • Kenner, Louisiana, Verenigde Staten, 70065
        • Ochsner Medical Center Kenner
      • Marrero, Louisiana, Verenigde Staten, 70072
        • West Jefferson Medical Center
      • Metairie, Louisiana, Verenigde Staten, 70006
        • East Jefferson General Hospital
      • Metairie, Louisiana, Verenigde Staten, 70006
        • Robert Veith MD LLC
      • Monroe, Louisiana, Verenigde Staten, 71202
        • Ochsner LSU Health Monroe Medical Center
      • New Orleans, Louisiana, Verenigde Staten, 70112
        • Tulane University School of Medicine
      • New Orleans, Louisiana, Verenigde Staten, 70121
        • Ochsner Medical Center Jefferson
      • New Orleans, Louisiana, Verenigde Staten, 70112
        • University Medical Center New Orleans
      • New Orleans, Louisiana, Verenigde Staten, 70112
        • Louisiana State University Health Science Center
      • Shreveport, Louisiana, Verenigde Staten, 71103
        • LSU Health Sciences Center at Shreveport
      • Shreveport, Louisiana, Verenigde Staten, 71105
        • CHRISTUS Highland Medical Center
    • Maine
      • Augusta, Maine, Verenigde Staten, 04330
        • Harold Alfond Center for Cancer Care
      • Bangor, Maine, Verenigde Staten, 04401
        • Eastern Maine Medical Center
      • Belfast, Maine, Verenigde Staten, 04915
        • MaineHealth Waldo Hospital
      • Biddeford, Maine, Verenigde Staten, 04005
        • MaineHealth Maine Medical Center - Biddeford
      • Brewer, Maine, Verenigde Staten, 04412
        • Lafayette Family Cancer Center-EMMC
      • Kennebunk, Maine, Verenigde Staten, 04043
        • New England Cancer Specialists - Kennebunk
      • Norway, Maine, Verenigde Staten, 04268
        • MaineHealth Stephens Hospital
      • Rockport, Maine, Verenigde Staten, 04856
        • Penobscot Bay Medical Center
      • Sanford, Maine, Verenigde Staten, 04073
        • MaineHealth Cancer Care and IV Therapy - Sanford
      • Scarborough, Maine, Verenigde Staten, 04074
        • MaineHealth Maine Medical Center- Scarborough
      • South Portland, Maine, Verenigde Staten, 04106
        • MaineHealth Cancer Care and IV Therapy - South Portland
      • Topsham, Maine, Verenigde Staten, 04086
        • New England Cancer Specialists - Topsham
      • Westbrook, Maine, Verenigde Staten, 04092
        • New England Cancer Specialists
    • Maryland
      • Annapolis, Maryland, Verenigde Staten, 21401
        • Luminis Health Anne Arundel Medical Center
      • Baltimore, Maryland, Verenigde Staten, 21237
        • MedStar Franklin Square Medical Center/Weinberg Cancer Institute
      • Baltimore, Maryland, Verenigde Staten, 21287
        • Johns Hopkins University/Sidney Kimmel Cancer Center
      • Baltimore, Maryland, Verenigde Staten, 21215
        • Sinai Hospital of Baltimore
      • Baltimore, Maryland, Verenigde Staten, 21204
        • Greater Baltimore Medical Center
      • Baltimore, Maryland, Verenigde Staten, 21201
        • University of Maryland/Greenebaum Cancer Center
      • Baltimore, Maryland, Verenigde Staten, 21218
        • MedStar Union Memorial Hospital
      • Baltimore, Maryland, Verenigde Staten, 21239
        • MedStar Good Samaritan Hospital
      • Bethesda, Maryland, Verenigde Staten, 20892
        • National Institutes of Health Clinical Center
      • Bethesda, Maryland, Verenigde Staten, 20889-5600
        • Walter Reed National Military Medical Center
      • Cumberland, Maryland, Verenigde Staten, 21502
        • UPMC Western Maryland
      • Easton, Maryland, Verenigde Staten, 21601
        • University of Maryland Shore Medical Center at Easton
      • Elkton, Maryland, Verenigde Staten, 21921
        • Christiana Care - Union Hospital
      • Frederick, Maryland, Verenigde Staten, 21701
        • Frederick Memorial Hospital
      • Frederick, Maryland, Verenigde Staten, 21702
        • FMH James M Stockman Cancer Institute
      • Olney, Maryland, Verenigde Staten, 20832
        • MedStar Montgomery Medical Center
      • Randallstown, Maryland, Verenigde Staten, 21133
        • Northwest Hospital Center
      • Salisbury, Maryland, Verenigde Staten, 21801
        • TidalHealth Peninsula Regional
      • Silver Spring, Maryland, Verenigde Staten, 20910
        • Holy Cross Hospital
      • Westminster, Maryland, Verenigde Staten, 21157
        • William E Kahlert Regional Cancer Center/Sinai Hospital
    • Massachusetts
      • Beverly, Massachusetts, Verenigde Staten, 01915
        • Beverly Hospital
      • Boston, Massachusetts, Verenigde Staten, 02215
        • Beth Israel Deaconess Medical Center
      • Boston, Massachusetts, Verenigde Staten, 02215
        • Dana-Farber Cancer Institute
      • Boston, Massachusetts, Verenigde Staten, 02111
        • Tufts Medical Center
      • Boston, Massachusetts, Verenigde Staten, 02118
        • Boston Medical Center
      • Boston, Massachusetts, Verenigde Staten, 02114
        • Massachusetts General Hospital Cancer Center
      • Burlington, Massachusetts, Verenigde Staten, 01805
        • Lahey Clinic
      • Fitchburg, Massachusetts, Verenigde Staten, 01420
        • Simonds-Sinon Regional Cancer Center
      • Framingham, Massachusetts, Verenigde Staten, 01702
        • MetroWest Medical Center-Framingham Union Hospital
      • Gloucester, Massachusetts, Verenigde Staten, 01930
        • Addison Gilbert Hospital
      • Lowell, Massachusetts, Verenigde Staten, 01854
        • Lowell General Hospital
      • Peabody, Massachusetts, Verenigde Staten, 01960
        • Lahey Clinic Peabody
      • Springfield, Massachusetts, Verenigde Staten, 01199
        • Baystate Medical Center
      • Springfield, Massachusetts, Verenigde Staten, 01104
        • Mercy Medical Center
      • Winchester, Massachusetts, Verenigde Staten, 01890
        • Beth Israel Deaconess Medical Center/Winchester Center for Cancer Care
      • Worcester, Massachusetts, Verenigde Staten, 01655
        • UMass Memorial Medical Center - University Campus
    • Michigan
      • Adrian, Michigan, Verenigde Staten, 49221
        • Hickman Cancer Center
      • Ann Arbor, Michigan, Verenigde Staten, 48109
        • C S Mott Children's Hospital
      • Ann Arbor, Michigan, Verenigde Staten, 48109
        • University of Michigan Rogel Cancer Center
      • Ann Arbor, Michigan, Verenigde Staten, 48106
        • Trinity Health Saint Joseph Mercy Hospital Ann Arbor
      • Battle Creek, Michigan, Verenigde Staten, 49017
        • Bronson Battle Creek
      • Brighton, Michigan, Verenigde Staten, 48114
        • Trinity Health IHA Medical Group Hematology Oncology - Brighton
      • Brighton, Michigan, Verenigde Staten, 48114
        • Trinity Health Medical Center - Brighton
      • Brownstown, Michigan, Verenigde Staten, 48183
        • Henry Ford Cancer Institute-Downriver
      • Canton, Michigan, Verenigde Staten, 48188
        • Trinity Health IHA Medical Group Hematology Oncology - Canton
      • Canton, Michigan, Verenigde Staten, 48188
        • Trinity Health Medical Center - Canton
      • Caro, Michigan, Verenigde Staten, 48723
        • Caro Cancer Center
      • Chelsea, Michigan, Verenigde Staten, 48118
        • Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital
      • Chelsea, Michigan, Verenigde Staten, 48118
        • Chelsea Hospital
      • Clarkston, Michigan, Verenigde Staten, 48346
        • Hematology Oncology Consultants-Clarkston
      • Clarkston, Michigan, Verenigde Staten, 48346
        • Newland Medical Associates-Clarkston
      • Clinton Township, Michigan, Verenigde Staten, 48038
        • Henry Ford Macomb Hospital-Clinton Township
      • Clinton Township, Michigan, Verenigde Staten, 48038
        • Henry Ford Hematology Oncology - Hayes
      • Dearborn, Michigan, Verenigde Staten, 48126
        • Henry Ford Medical Center-Fairlane
      • Dearborn, Michigan, Verenigde Staten, 48124
        • Corewell Health Dearborn Hospital
      • Detroit, Michigan, Verenigde Staten, 48202
        • Henry Ford Hospital
      • Detroit, Michigan, Verenigde Staten, 48201
        • Wayne State University/Karmanos Cancer Institute
      • Detroit, Michigan, Verenigde Staten, 48236
        • Henry Ford Health Saint John Hospital
      • East China Township, Michigan, Verenigde Staten, 48054
        • Henry Ford River District Hospital
      • East Lansing, Michigan, Verenigde Staten, 48823
        • Michigan State University
      • Escanaba, Michigan, Verenigde Staten, 49829
        • OSF Saint Francis Hospital and Medical Group
      • Farmington Hills, Michigan, Verenigde Staten, 48336
        • Corewell Health Farmington Hills Hospital
      • Flint, Michigan, Verenigde Staten, 48503
        • Hurley Medical Center
      • Flint, Michigan, Verenigde Staten, 48503
        • Genesee Hematology Oncology PC
      • Flint, Michigan, Verenigde Staten, 48503
        • Genesys Hurley Cancer Institute
      • Flint, Michigan, Verenigde Staten, 48503
        • Cancer Hematology Centers - Flint
      • Grand Rapids, Michigan, Verenigde Staten, 49503
        • Trinity Health Grand Rapids Hospital
      • Grand Rapids, Michigan, Verenigde Staten, 49503
        • Corewell Health Grand Rapids Hospitals - Butterworth Hospital
      • Grand Rapids, Michigan, Verenigde Staten, 49503
        • Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital
      • Grosse Pointe, Michigan, Verenigde Staten, 48230
        • William Beaumont Hospital-Grosse Pointe
      • Grosse Pointe Woods, Michigan, Verenigde Staten, 48236
        • Henry Ford Saint John Hospital - Academic
      • Grosse Pointe Woods, Michigan, Verenigde Staten, 48236
        • Henry Ford Saint John Hospital - Breast
      • Grosse Pointe Woods, Michigan, Verenigde Staten, 48236
        • Henry Ford Saint John Hospital - Van Elslander
      • Jackson, Michigan, Verenigde Staten, 49201
        • Allegiance Health
      • Kalamazoo, Michigan, Verenigde Staten, 49007
        • West Michigan Cancer Center
      • Kalamazoo, Michigan, Verenigde Staten, 49007
        • Bronson Methodist Hospital
      • Kalamazoo, Michigan, Verenigde Staten, 49048
        • Beacon Kalamazoo
      • Lansing, Michigan, Verenigde Staten, 48910
        • Karmanos Cancer Institute at McLaren Greater Lansing
      • Lansing, Michigan, Verenigde Staten, 48912
        • University of Michigan Health - Sparrow Lansing
      • Livonia, Michigan, Verenigde Staten, 48154
        • Trinity Health Saint Mary Mercy Livonia Hospital
      • Livonia, Michigan, Verenigde Staten, 48154
        • Hope Cancer Clinic
      • Macomb, Michigan, Verenigde Staten, 48044
        • Henry Ford Warren Hospital - Breast Macomb
      • Macomb, Michigan, Verenigde Staten, 48044
        • Henry Ford Saint John Hospital - Macomb Medical
      • Marlette, Michigan, Verenigde Staten, 48453
        • Saint Mary's Oncology/Hematology Associates of Marlette
      • Midland, Michigan, Verenigde Staten, 48670
        • MyMichigan Medical Center Midland
      • Monroe, Michigan, Verenigde Staten, 48162
        • Toledo Clinic Cancer Centers-Monroe
      • Monroe, Michigan, Verenigde Staten, 48162
        • Monroe Cancer Center
      • Muskegon, Michigan, Verenigde Staten, 49444
        • Trinity Health Muskegon Hospital
      • Niles, Michigan, Verenigde Staten, 49120
        • Corewell Health Lakeland Hospitals - Niles Hospital
      • Norton Shores, Michigan, Verenigde Staten, 49444
        • Cancer and Hematology Centers of Western Michigan - Norton Shores
      • Novi, Michigan, Verenigde Staten, 48377
        • Henry Ford Medical Center-Columbus
      • Novi, Michigan, Verenigde Staten, 48374
        • Henry Ford Health Providence Novi Hospital
      • Pontiac, Michigan, Verenigde Staten, 48341
        • Hope Cancer Center
      • Pontiac, Michigan, Verenigde Staten, 48341
        • Trinity Health Saint Joseph Mercy Oakland Hospital
      • Pontiac, Michigan, Verenigde Staten, 48341
        • Michigan Healthcare Professionals Pontiac
      • Pontiac, Michigan, Verenigde Staten, 48341
        • Trinity Health IHA Medical Group-Alice Gustafson Center
      • Port Huron, Michigan, Verenigde Staten, 48060
        • Lake Huron Medical Center
      • Port Huron, Michigan, Verenigde Staten, 48060
        • Huron Medical Center PC
      • Reed City, Michigan, Verenigde Staten, 49677
        • Corewell Health Reed City Hospital
      • Rochester Hills, Michigan, Verenigde Staten, 48309
        • Henry Ford Rochester Hospital
      • Roseville, Michigan, Verenigde Staten, 48066
        • Michigan Cancer Specialists
      • Royal Oak, Michigan, Verenigde Staten, 48073
        • Cancer Care Associates PC
      • Royal Oak, Michigan, Verenigde Staten, 48073
        • Comprehensive Medical Center PLLC
      • Royal Oak, Michigan, Verenigde Staten, 48073
        • Oakland Medical Group
      • Royal Oak, Michigan, Verenigde Staten, 48067
        • Oakland Colon Rectal Associates
      • Royal Oak, Michigan, Verenigde Staten, 48073
        • Hematology Oncology Consultants PC-Royal Oak
      • Royal Oak, Michigan, Verenigde Staten, 48073
        • Corewell Health William Beaumont University Hospital
      • Royal Oak, Michigan, Verenigde Staten, 48073
        • Corewell Health Children's
      • Saginaw, Michigan, Verenigde Staten, 48604
        • Oncology Hematology Associates of Saginaw Valley PC
      • Saginaw, Michigan, Verenigde Staten, 48601
        • MyMichigan Medical Center Saginaw
      • Saint Joseph, Michigan, Verenigde Staten, 49085
        • Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center
      • Saint Joseph, Michigan, Verenigde Staten, 49085
        • Corewell Health Lakeland Hospitals - Saint Joseph Hospital
      • Shelby, Michigan, Verenigde Staten, 48315
        • Henry Ford Macomb Health Center - Shelby Township
      • Southfield, Michigan, Verenigde Staten, 48075
        • Henry Ford Health Providence Southfield Hospital
      • Sterling Heights, Michigan, Verenigde Staten, 48312
        • Bhadresh Nayak MD PC-Sterling Heights
      • Sterling Heights, Michigan, Verenigde Staten, 48312
        • Premier Hematology Oncology Care
      • Sterling Heights, Michigan, Verenigde Staten, 48314
        • Mitchell Folbe MD PC
      • Tawas City, Michigan, Verenigde Staten, 48764
        • MyMichigan Medical Center Tawas
      • Traverse City, Michigan, Verenigde Staten, 49684
        • Munson Medical Center
      • Troy, Michigan, Verenigde Staten, 48084
        • Michigan Institute of Urology-Town Center
      • Troy, Michigan, Verenigde Staten, 48085
        • Claudia BR Herke MD PC
      • Troy, Michigan, Verenigde Staten, 48098
        • Hematology Oncology Consultants PC-Troy
      • Troy, Michigan, Verenigde Staten, 48085
        • Corewell Health Beaumont Troy Hospital
      • Warren, Michigan, Verenigde Staten, 48088
        • Advanced Breast Care Center PLLC
      • Warren, Michigan, Verenigde Staten, 48093
        • Macomb Hematology Oncology PC
      • Warren, Michigan, Verenigde Staten, 48093
        • Henry Ford Madison Heights Hospital - Breast
      • Warren, Michigan, Verenigde Staten, 48093
        • Henry Ford Health Warren Hospital
      • Warren, Michigan, Verenigde Staten, 48093
        • Henry Ford Warren Hospital - GLCMS
      • West Bloomfield, Michigan, Verenigde Staten, 48322
        • Henry Ford West Bloomfield Hospital
      • West Branch, Michigan, Verenigde Staten, 48661
        • Saint Mary's Oncology/Hematology Associates of West Branch
      • Wyandotte, Michigan, Verenigde Staten, 48192
        • Henry Ford Wyandotte Hospital
      • Wyoming, Michigan, Verenigde Staten, 49519
        • University of Michigan Health - West
      • Ypsilanti, Michigan, Verenigde Staten, 48197
        • Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus
      • Ypsilanti, Michigan, Verenigde Staten, 48106
        • Huron Gastroenterology PC
    • Minnesota
      • Aitkin, Minnesota, Verenigde Staten, 56431
        • Riverwood Healthcare Center
      • Baxter, Minnesota, Verenigde Staten, 56425
        • Essentia Health - Baxter Clinic
      • Bemidji, Minnesota, Verenigde Staten, 56601
        • Sanford Joe Lueken Cancer Center
      • Brainerd, Minnesota, Verenigde Staten, 56401
        • Essentia Health Saint Joseph's Medical Center
      • Burnsville, Minnesota, Verenigde Staten, 55337
        • Fairview Ridges Hospital
      • Burnsville, Minnesota, Verenigde Staten, 55337
        • Minnesota Oncology - Burnsville
      • Cambridge, Minnesota, Verenigde Staten, 55008
        • Cambridge Medical Center
      • Coon Rapids, Minnesota, Verenigde Staten, 55433
        • Mercy Hospital
      • Deer River, Minnesota, Verenigde Staten, 56636
        • Essentia Health - Deer River Clinic
      • Detroit Lakes, Minnesota, Verenigde Staten, 56501
        • Essentia Health Saint Mary's - Detroit Lakes Clinic
      • Duluth, Minnesota, Verenigde Staten, 55805
        • Essentia Health Cancer Center
      • Duluth, Minnesota, Verenigde Staten, 55805
        • Essentia Health Saint Mary's Medical Center
      • Duluth, Minnesota, Verenigde Staten, 55805
        • Miller-Dwan Hospital
      • Edina, Minnesota, Verenigde Staten, 55435
        • Fairview Southdale Hospital
      • Ely, Minnesota, Verenigde Staten, 55731
        • Essentia Health - Ely Clinic
      • Fergus Falls, Minnesota, Verenigde Staten, 56537
        • Lake Region Healthcare Corporation-Cancer Care
      • Fosston, Minnesota, Verenigde Staten, 56542
        • Essentia Health - Fosston
      • Fridley, Minnesota, Verenigde Staten, 55432
        • Unity Hospital
      • Hibbing, Minnesota, Verenigde Staten, 55746
        • Essentia Health Hibbing Clinic
      • International Falls, Minnesota, Verenigde Staten, 56649
        • Essentia Health - International Falls Clinic
      • Maple Grove, Minnesota, Verenigde Staten, 55369
        • Fairview Clinics and Surgery Center Maple Grove
      • Maplewood, Minnesota, Verenigde Staten, 55109
        • Saint John's Hospital - Healtheast
      • Maplewood, Minnesota, Verenigde Staten, 55109
        • Minnesota Oncology Hematology PA-Maplewood
      • Minneapolis, Minnesota, Verenigde Staten, 55415
        • Hennepin County Medical Center
      • Minneapolis, Minnesota, Verenigde Staten, 55407
        • Abbott-Northwestern Hospital
      • Minneapolis, Minnesota, Verenigde Staten, 55454
        • Health Partners Inc
      • Minneapolis, Minnesota, Verenigde Staten, 55455
        • University of Minnesota/Masonic Cancer Center
      • Monticello, Minnesota, Verenigde Staten, 55362
        • Monticello Cancer Center
      • Moose Lake, Minnesota, Verenigde Staten, 55767
        • Essentia Health - Moose Lake Clinic
      • New Ulm, Minnesota, Verenigde Staten, 56073
        • New Ulm Medical Center
      • Park Rapids, Minnesota, Verenigde Staten, 56470
        • Essentia Health - Park Rapids
      • Princeton, Minnesota, Verenigde Staten, 55371
        • Fairview Northland Medical Center
      • Robbinsdale, Minnesota, Verenigde Staten, 55422
        • North Memorial Medical Health Center
      • Rochester, Minnesota, Verenigde Staten, 55905
        • Mayo Clinic in Rochester
      • Saint Louis Park, Minnesota, Verenigde Staten, 55416
        • Park Nicollet Clinic - Saint Louis Park
      • Saint Paul, Minnesota, Verenigde Staten, 55101
        • Regions Hospital
      • Saint Paul, Minnesota, Verenigde Staten, 55102
        • United Hospital
      • Sandstone, Minnesota, Verenigde Staten, 55072
        • Essentia Health Sandstone
      • Shakopee, Minnesota, Verenigde Staten, 55379
        • Saint Francis Regional Medical Center
      • Stillwater, Minnesota, Verenigde Staten, 55082
        • Lakeview Hospital
      • Virginia, Minnesota, Verenigde Staten, 55792
        • Essentia Health Virginia Clinic
      • Waconia, Minnesota, Verenigde Staten, 55387
        • Ridgeview Medical Center
      • Willmar, Minnesota, Verenigde Staten, 56201
        • Rice Memorial Hospital
      • Woodbury, Minnesota, Verenigde Staten, 55125
        • Minnesota Oncology Hematology PA-Woodbury
      • Worthington, Minnesota, Verenigde Staten, 56187
        • Sanford Cancer Center Worthington
      • Wyoming, Minnesota, Verenigde Staten, 55092
        • Fairview Lakes Medical Center
    • Mississippi
      • Columbus, Mississippi, Verenigde Staten, 39705
        • Baptist Memorial Hospital and Cancer Center-Golden Triangle
      • Grenada, Mississippi, Verenigde Staten, 38901
        • Baptist Cancer Center-Grenada
      • Hattiesburg, Mississippi, Verenigde Staten, 39401
        • Hattiesburg Clinic - Hematology/Oncology Clinic
      • Hattiesburg, Mississippi, Verenigde Staten, 39404
        • Forrest General Hospital / Cancer Center
      • Jackson, Mississippi, Verenigde Staten, 39216
        • University of Mississippi Medical Center
      • New Albany, Mississippi, Verenigde Staten, 38652
        • Baptist Memorial Hospital and Cancer Center-Union County
      • Oxford, Mississippi, Verenigde Staten, 38655
        • Baptist Memorial Hospital and Cancer Center-Oxford
      • Pascagoula, Mississippi, Verenigde Staten, 39581
        • Singing River Hospital
      • Southhaven, Mississippi, Verenigde Staten, 38671
        • Baptist Memorial Hospital and Cancer Center-Desoto
    • Missouri
      • Bolivar, Missouri, Verenigde Staten, 65613
        • Central Care Cancer Center - Bolivar
      • Bonne Terre, Missouri, Verenigde Staten, 63628
        • Parkland Health Center-Bonne Terre
      • Branson, Missouri, Verenigde Staten, 65616
        • Cox Cancer Center Branson
      • Cape Girardeau, Missouri, Verenigde Staten, 63703
        • Saint Francis Medical Center
      • Cape Girardeau, Missouri, Verenigde Staten, 63703
        • Mercy Cancer Center - Cape Girardeau
      • Chesterfield, Missouri, Verenigde Staten, 63017
        • Saint Luke's Hospital
      • City of Saint Peters, Missouri, Verenigde Staten, 63376
        • Siteman Cancer Center at Saint Peters Hospital
      • Columbia, Missouri, Verenigde Staten, 65212
        • MU Health - University Hospital/Ellis Fischel Cancer Center
      • Creve Coeur, Missouri, Verenigde Staten, 63141
        • Siteman Cancer Center at West County Hospital
      • Farmington, Missouri, Verenigde Staten, 63640
        • Parkland Health Center - Farmington
      • Independence, Missouri, Verenigde Staten, 64057
        • Centerpoint Medical Center LLC
      • Jefferson City, Missouri, Verenigde Staten, 65109
        • MU Health Care Goldschmidt Cancer Center
      • Joplin, Missouri, Verenigde Staten, 64804
        • Freeman Health System
      • Joplin, Missouri, Verenigde Staten, 64804
        • Mercy Hospital Joplin
      • Kansas City, Missouri, Verenigde Staten, 64154
        • University of Kansas Cancer Center - North
      • Kansas City, Missouri, Verenigde Staten, 64131
        • The University of Kansas Cancer Center-South
      • Kansas City, Missouri, Verenigde Staten, 64111
        • Saint Luke's Hospital of Kansas City
      • Kansas City, Missouri, Verenigde Staten, 64132
        • Research Medical Center
      • Kansas City, Missouri, Verenigde Staten, 64108
        • University Health Truman Medical Center
      • Lee's Summit, Missouri, Verenigde Staten, 64064
        • University of Kansas Cancer Center - Lee's Summit
      • Lee's Summit, Missouri, Verenigde Staten, 64086
        • Saint Luke's East - Lee's Summit
      • Liberty, Missouri, Verenigde Staten, 64068
        • Liberty Hospital
      • North Kansas City, Missouri, Verenigde Staten, 64116
        • University of Kansas Cancer Center at North Kansas City Hospital
      • Rolla, Missouri, Verenigde Staten, 65401
        • Mercy Clinic-Rolla-Cancer and Hematology
      • Rolla, Missouri, Verenigde Staten, 65401
        • Phelps Health Delbert Day Cancer Institute
      • Saint Joseph, Missouri, Verenigde Staten, 64506
        • Heartland Regional Medical Center
      • Sainte Genevieve, Missouri, Verenigde Staten, 63670
        • Sainte Genevieve County Memorial Hospital
      • Springfield, Missouri, Verenigde Staten, 65807
        • CoxHealth South Hospital
      • Springfield, Missouri, Verenigde Staten, 65804
        • Mercy Hospital Springfield
      • St Louis, Missouri, Verenigde Staten, 63110
        • Washington University School of Medicine
      • St Louis, Missouri, Verenigde Staten, 63129
        • Siteman Cancer Center-South County
      • St Louis, Missouri, Verenigde Staten, 63136
        • Siteman Cancer Center at Christian Hospital
      • St Louis, Missouri, Verenigde Staten, 63131
        • Missouri Baptist Medical Center
      • St Louis, Missouri, Verenigde Staten, 63109
        • Mercy Infusion Center - Chippewa
      • St Louis, Missouri, Verenigde Staten, 63141
        • Mercy Hospital Saint Louis
      • St Louis, Missouri, Verenigde Staten, 63128
        • Mercy Hospital South
      • Sullivan, Missouri, Verenigde Staten, 63080
        • Missouri Baptist Sullivan Hospital
    • Montana
      • Anaconda, Montana, Verenigde Staten, 59711
        • Community Hospital of Anaconda
      • Billings, Montana, Verenigde Staten, 59101
        • Billings Clinic Cancer Center
      • Billings, Montana, Verenigde Staten, 59101
        • Saint Vincent Healthcare
      • Billings, Montana, Verenigde Staten, 59102
        • Saint Vincent Frontier Cancer Center
      • Bozeman, Montana, Verenigde Staten, 59715
        • Bozeman Health Deaconess Hospital
      • Butte, Montana, Verenigde Staten, 59701
        • Saint James Community Hospital and Cancer Treatment Center
      • Great Falls, Montana, Verenigde Staten, 59405
        • Benefis Sletten Cancer Institute
      • Helena, Montana, Verenigde Staten, 59601
        • Saint Peter's Community Hospital
      • Kalispell, Montana, Verenigde Staten, 59901
        • Logan Health Medical Center
      • Missoula, Montana, Verenigde Staten, 59802
        • Saint Patrick Hospital - Community Hospital
      • Missoula, Montana, Verenigde Staten, 59804
        • Community Medical Center
    • Nebraska
      • Bellevue, Nebraska, Verenigde Staten, 68123
        • Nebraska Medicine-Bellevue
      • Grand Island, Nebraska, Verenigde Staten, 68803
        • Nebraska Cancer Specialists/Oncology Hematology West PC
      • Kearney, Nebraska, Verenigde Staten, 68847
        • CHI Health Good Samaritan
      • Kearney, Nebraska, Verenigde Staten, 68845
        • Fred and Pamela Buffett Cancer Center - Kearney
      • Lincoln, Nebraska, Verenigde Staten, 68506
        • Nebraska Hematology and Oncology
      • Lincoln, Nebraska, Verenigde Staten, 68510
        • Nebraska Cancer Research Center
      • Lincoln, Nebraska, Verenigde Staten, 68510
        • Saint Elizabeth Regional Medical Center
      • Lincoln, Nebraska, Verenigde Staten, 68516
        • Cancer Partners of Nebraska
      • Norfolk, Nebraska, Verenigde Staten, 68701
        • Faith Regional Health Services Carson Cancer Center
      • North Platte, Nebraska, Verenigde Staten, 69101
        • Great Plains Health Callahan Cancer Center
      • Omaha, Nebraska, Verenigde Staten, 68114
        • Nebraska Methodist Hospital
      • Omaha, Nebraska, Verenigde Staten, 68198
        • University of Nebraska Medical Center
      • Omaha, Nebraska, Verenigde Staten, 68124
        • Alegent Health Bergan Mercy Medical Center
      • Omaha, Nebraska, Verenigde Staten, 68118
        • Nebraska Medicine-Village Pointe
      • Omaha, Nebraska, Verenigde Staten, 68122
        • Alegent Health Immanuel Medical Center
      • Omaha, Nebraska, Verenigde Staten, 68130
        • Alegent Health Lakeside Hospital
      • Omaha, Nebraska, Verenigde Staten, 68124
        • Nebraska Cancer Specialists - Omaha
      • Omaha, Nebraska, Verenigde Staten, 68130
        • Oncology Hematology West PC
      • Omaha, Nebraska, Verenigde Staten, 68122
        • Hematology and Oncology Consultants PC
      • Omaha, Nebraska, Verenigde Staten, 68114
        • Oncology Associates PC
      • Omaha, Nebraska, Verenigde Staten, 68114
        • Nebraska Cancer Specialists/Oncology Hematology West PC - MECC
      • Papillion, Nebraska, Verenigde Staten, 68046
        • Midlands Community Hospital
      • Scottsbluff, Nebraska, Verenigde Staten, 69361
        • Regional West Medical Center Cancer Center
    • Nevada
      • Carson City, Nevada, Verenigde Staten, 89703
        • Carson Tahoe Regional Medical Center
      • Henderson, Nevada, Verenigde Staten, 89052
        • Comprehensive Cancer Centers of Nevada - Henderson
      • Henderson, Nevada, Verenigde Staten, 89052
        • Cancer and Blood Specialists-Henderson
      • Henderson, Nevada, Verenigde Staten, 89052
        • Las Vegas Cancer Center-Henderson
      • Henderson, Nevada, Verenigde Staten, 89074
        • Comprehensive Cancer Centers of Nevada-Southeast Henderson
      • Henderson, Nevada, Verenigde Staten, 89052
        • Comprehensive Cancer Centers of Nevada-Horizon Ridge
      • Henderson, Nevada, Verenigde Staten, 89074
        • Las Vegas Urology - Green Valley
      • Henderson, Nevada, Verenigde Staten, 89074
        • Las Vegas Urology - Pebble
      • Henderson, Nevada, Verenigde Staten, 89074
        • Urology Specialists of Nevada - Green Valley
      • Henderson, Nevada, Verenigde Staten, 89074
        • Oncology Las Vegas - Henderson
      • Las Vegas, Nevada, Verenigde Staten, 89144
        • Summerlin Hospital Medical Center
      • Las Vegas, Nevada, Verenigde Staten, 89109
        • Sunrise Hospital and Medical Center
      • Las Vegas, Nevada, Verenigde Staten, 89102
        • OptumCare Cancer Care at Charleston
      • Las Vegas, Nevada, Verenigde Staten, 89106
        • Radiation Oncology Centers of Nevada Central
      • Las Vegas, Nevada, Verenigde Staten, 89119
        • Radiation Oncology Centers of Nevada Southeast
      • Las Vegas, Nevada, Verenigde Staten, 89128
        • Comprehensive Cancer Centers of Nevada - Northwest
      • Las Vegas, Nevada, Verenigde Staten, 89128
        • OptumCare Cancer Care at MountainView
      • Las Vegas, Nevada, Verenigde Staten, 89135
        • Alliance for Childhood Diseases/Cure 4 the Kids Foundation
      • Las Vegas, Nevada, Verenigde Staten, 89144
        • Comprehensive Cancer Centers of Nevada - Town Center
      • Las Vegas, Nevada, Verenigde Staten, 89144
        • Comprehensive Cancer Centers of Nevada-Summerlin
      • Las Vegas, Nevada, Verenigde Staten, 89148
        • Comprehensive Cancer Centers of Nevada
      • Las Vegas, Nevada, Verenigde Staten, 89169
        • Comprehensive Cancer Centers of Nevada - Central Valley
      • Las Vegas, Nevada, Verenigde Staten, 89102
        • University Medical Center of Southern Nevada
      • Las Vegas, Nevada, Verenigde Staten, 89106
        • Cancer and Blood Specialists-Shadow
      • Las Vegas, Nevada, Verenigde Staten, 89109
        • HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway
      • Las Vegas, Nevada, Verenigde Staten, 89113
        • HealthCare Partners Medical Group Oncology/Hematology-San Martin
      • Las Vegas, Nevada, Verenigde Staten, 89121
        • Cancer Therapy and Integrative Medicine
      • Las Vegas, Nevada, Verenigde Staten, 89128
        • Cancer and Blood Specialists-Tenaya
      • Las Vegas, Nevada, Verenigde Staten, 89128
        • HealthCare Partners Medical Group Oncology/Hematology-Tenaya
      • Las Vegas, Nevada, Verenigde Staten, 89148-2405
        • Las Vegas Cancer Center-Medical Center
      • Las Vegas, Nevada, Verenigde Staten, 89149
        • HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills
      • Las Vegas, Nevada, Verenigde Staten, 89128
        • Ann M Wierman MD LTD
      • Las Vegas, Nevada, Verenigde Staten, 89074
        • Las Vegas Urology - Pecos
      • Las Vegas, Nevada, Verenigde Staten, 89102
        • Desert West Surgery
      • Las Vegas, Nevada, Verenigde Staten, 89106
        • Urology Specialists of Nevada - Central
      • Las Vegas, Nevada, Verenigde Staten, 89113
        • Las Vegas Prostate Cancer Center
      • Las Vegas, Nevada, Verenigde Staten, 89113
        • Las Vegas Urology - Sunset
      • Las Vegas, Nevada, Verenigde Staten, 89128
        • Las Vegas Urology - Cathedral Rock
      • Las Vegas, Nevada, Verenigde Staten, 89128
        • Las Vegas Urology - Smoke Ranch
      • Las Vegas, Nevada, Verenigde Staten, 89128
        • Urology Specialists of Nevada - Northwest
      • Las Vegas, Nevada, Verenigde Staten, 89113
        • Urology Specialists of Nevada - Southwest
      • Las Vegas, Nevada, Verenigde Staten, 89128
        • Oncology Las Vegas - Tenaya
      • Las Vegas, Nevada, Verenigde Staten, 89183
        • OptumCare Cancer Care at Fort Apache
      • Pahrump, Nevada, Verenigde Staten, 89048
        • Hope Cancer Care of Nevada-Pahrump
      • Reno, Nevada, Verenigde Staten, 89502
        • Renown Regional Medical Center
      • Reno, Nevada, Verenigde Staten, 89503
        • Saint Mary's Regional Medical Center
      • Reno, Nevada, Verenigde Staten, 89509
        • Radiation Oncology Associates
      • Reno, Nevada, Verenigde Staten, 89502
        • Center of Hope at Renown Medical Center
    • New Hampshire
      • Concord, New Hampshire, Verenigde Staten, 03301
        • New Hampshire Oncology Hematology PA-Concord
      • Lebanon, New Hampshire, Verenigde Staten, 03756
        • Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center
      • Manchester, New Hampshire, Verenigde Staten, 03103
        • Solinsky Center for Cancer Care
      • Manchester, New Hampshire, Verenigde Staten, 03103
        • Elliot Hospital
      • Manchester, New Hampshire, Verenigde Staten, 03104
        • Dartmouth Cancer Center - Manchester/ DCC Manchester
      • Nashua, New Hampshire, Verenigde Staten, 03063
        • Dartmouth Cancer Center - Nashua
    • New Jersey
      • Brick, New Jersey, Verenigde Staten, 08724
        • Ocean University Medical Center
      • Cape May Court House, New Jersey, Verenigde Staten, 08210
        • AtlantiCare Health Park-Cape May Court House
      • Egg Harbor, New Jersey, Verenigde Staten, 08234
        • AtlantiCare Surgery Center
      • Elizabeth, New Jersey, Verenigde Staten, 07207
        • Trinitas Hospital and Comprehensive Cancer Center - Williamson Street Campus
      • Flemington, New Jersey, Verenigde Staten, 08822
        • Hunterdon Medical Center
      • Hackensack, New Jersey, Verenigde Staten, 07601
        • Hackensack University Medical Center
      • Holmdel, New Jersey, Verenigde Staten, 07733
        • Bayshore Community Hospital
      • Lakewood, New Jersey, Verenigde Staten, 08701
        • Monmouth Medical Center Southern Campus
      • Livingston, New Jersey, Verenigde Staten, 07039
        • Cooperman Barnabas Medical Center
      • Long Branch, New Jersey, Verenigde Staten, 07740
        • Monmouth Medical Center
      • Manahawkin, New Jersey, Verenigde Staten, 08050
        • Southern Ocean County Medical Center
      • Middletown, New Jersey, Verenigde Staten, 07748
        • Memorial Sloan Kettering Monmouth
      • Morristown, New Jersey, Verenigde Staten, 07960
        • Morristown Medical Center
      • Mullica Hill, New Jersey, Verenigde Staten, 08062
        • Inspira Medical Center Mullica Hill
      • Neptune City, New Jersey, Verenigde Staten, 07753
        • Jersey Shore Medical Center
      • New Brunswick, New Jersey, Verenigde Staten, 08903
        • Rutgers Cancer Institute of New Jersey
      • Newark, New Jersey, Verenigde Staten, 07112
        • Newark Beth Israel Medical Center
      • Pennington, New Jersey, Verenigde Staten, 08534
        • Capital Health Medical Center-Hopewell
      • Red Bank, New Jersey, Verenigde Staten, 07701
        • Riverview Medical Center/Booker Cancer Center
      • Sewell, New Jersey, Verenigde Staten, 08080
        • Sidney Kimmel Cancer Center Washington Township
      • Summit, New Jersey, Verenigde Staten, 07902
        • Overlook Hospital
      • Vineland, New Jersey, Verenigde Staten, 08360
        • Inspira Medical Center Vineland
    • New Mexico
      • Albuquerque, New Mexico, Verenigde Staten, 87106
        • Southwest Gynecologic Oncology Associates Inc
      • Albuquerque, New Mexico, Verenigde Staten, 87102
        • Lovelace Medical Center-Downtown
      • Albuquerque, New Mexico, Verenigde Staten, 87109
        • New Mexico Oncology Hematology Consultants
      • Albuquerque, New Mexico, Verenigde Staten, 87106
        • University of New Mexico Cancer Center
      • Albuquerque, New Mexico, Verenigde Staten, 87110
        • Presbyterian Kaseman Hospital
      • Las Cruces, New Mexico, Verenigde Staten, 88011
        • Memorial Medical Center-Las Cruces
      • Rio Rancho, New Mexico, Verenigde Staten, 87124
        • Presbyterian Rust Medical Center/Jorgensen Cancer Center
      • Santa Fe, New Mexico, Verenigde Staten, 87505
        • Christus Saint Vincent Regional Cancer Center
    • New York
      • Bay Shore, New York, Verenigde Staten, 11706
        • South Shore University Hospital
      • Brooklyn, New York, Verenigde Staten, 11203
        • State University of New York Downstate Medical Center
      • Buffalo, New York, Verenigde Staten, 14263
        • Roswell Park Cancer Institute
      • Elmira, New York, Verenigde Staten, 14905
        • Arnot Ogden Medical Center/Falck Cancer Center
      • Glens Falls, New York, Verenigde Staten, 12801
        • Glens Falls Hospital
      • Harrison, New York, Verenigde Staten, 10604
        • Memorial Sloan Kettering Westchester
      • Lake Success, New York, Verenigde Staten, 11042
        • Northwell Health/Center for Advanced Medicine
      • Manhasset, New York, Verenigde Staten, 11030
        • North Shore University Hospital
      • New Hyde Park, New York, Verenigde Staten, 11040
        • Long Island Jewish Medical Center
      • New York, New York, Verenigde Staten, 10065
        • Memorial Sloan Kettering Cancer Center
      • New York, New York, Verenigde Staten, 10029
        • Mount Sinai Hospital
      • New York, New York, Verenigde Staten, 10032
        • NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center
      • New York, New York, Verenigde Staten, 10065
        • NYP/Weill Cornell Medical Center
      • New York, New York, Verenigde Staten, 10075
        • Lenox Hill Hospital
      • New York, New York, Verenigde Staten, 10065
        • Manhattan Eye Ear and Throat Hospital
      • Rochester, New York, Verenigde Staten, 14642
        • University of Rochester
      • Rochester, New York, Verenigde Staten, 14621
        • Rochester General Hospital
      • Stony Brook, New York, Verenigde Staten, 11794
        • Stony Brook University Medical Center
      • Syracuse, New York, Verenigde Staten, 13210
        • State University of New York Upstate Medical University
      • Syracuse, New York, Verenigde Staten, 13215
        • SUNY Upstate Medical Center-Community Campus
      • The Bronx, New York, Verenigde Staten, 10461
        • Montefiore Medical Center-Einstein Campus
      • The Bronx, New York, Verenigde Staten, 10467
        • Children's Hospital at Montefiore
      • The Bronx, New York, Verenigde Staten, 10467
        • Montefiore Medical Center - Moses Campus
      • The Bronx, New York, Verenigde Staten, 10461
        • Montefiore Medical Center-Weiler Hospital
      • White Plains, New York, Verenigde Staten, 10601
        • Dickstein Cancer Treatment Center
    • North Carolina
      • Asheville, North Carolina, Verenigde Staten, 28801
        • Mission Hospital
      • Asheville, North Carolina, Verenigde Staten, 28816
        • Hope Women's Cancer Centers-Asheville
      • Asheville, North Carolina, Verenigde Staten, 28806
        • Messino Cancer Centers
      • Asheville, North Carolina, Verenigde Staten, 28803
        • AdventHealth Infusion Center Asheville
      • Cary, North Carolina, Verenigde Staten, 27518
        • Waverly Hematology Oncology
      • Chapel Hill, North Carolina, Verenigde Staten, 27599
        • UNC Lineberger Comprehensive Cancer Center
      • Charlotte, North Carolina, Verenigde Staten, 28204
        • Novant Health Presbyterian Medical Center
      • Charlotte, North Carolina, Verenigde Staten, 28207
        • Oncology Specialists of Charlotte
      • Charlotte, North Carolina, Verenigde Staten, 28262
        • Southern Oncology Specialists-Charlotte
      • Charlotte, North Carolina, Verenigde Staten, 28207
        • Novant Health Carolina Surgical - Randolph
      • Clinton, North Carolina, Verenigde Staten, 28328
        • Southeastern Medical Oncology Center-Clinton
      • Clyde, North Carolina, Verenigde Staten, 28721
        • AdventHealth Infusion Center Haywood
      • Durham, North Carolina, Verenigde Staten, 27710
        • Duke University Medical Center
      • Durham, North Carolina, Verenigde Staten, 27705
        • Durham VA Medical Center
      • Goldsboro, North Carolina, Verenigde Staten, 27534
        • Southeastern Medical Oncology Center-Goldsboro
      • Goldsboro, North Carolina, Verenigde Staten, 27534
        • Wayne Memorial Hospital
      • Greensboro, North Carolina, Verenigde Staten, 27403
        • Novant Health Breast Surgery - Greensboro
      • Hendersonville, North Carolina, Verenigde Staten, 28791
        • Margaret R Pardee Memorial Hospital
      • Hendersonville, North Carolina, Verenigde Staten, 28792
        • AdventHealth Hendersonville
      • Huntersville, North Carolina, Verenigde Staten, 28078
        • Novant Health Cancer Institute - Huntersville
      • Huntersville, North Carolina, Verenigde Staten, 28078
        • Southern Oncology Specialists-Huntersville
      • Huntersville, North Carolina, Verenigde Staten, 28078
        • Novant Health Presbyterian Medical Center Huntersville
      • Jacksonville, North Carolina, Verenigde Staten, 28546
        • Southeastern Medical Oncology Center-Jacksonville
      • Jacksonville, North Carolina, Verenigde Staten, 28546
        • Onslow Memorial Hospital
      • Kernersville, North Carolina, Verenigde Staten, 27284
        • Novant Health Cancer Institute - Kernersville
      • Matthews, North Carolina, Verenigde Staten, 28105
        • Matthews Radiation Oncology Center
      • Matthews, North Carolina, Verenigde Staten, 28105
        • Novant Health Cancer Institute - Matthews
      • Mooresville, North Carolina, Verenigde Staten, 28117
        • Novant Health Cancer Institute - Mooresville
      • Mount Airy, North Carolina, Verenigde Staten, 27030
        • Novant Health Cancer Institute - Mount Airy
      • North Wilkesboro, North Carolina, Verenigde Staten, 28659
        • Novant Health Cancer Institute - Wilkesboro
      • Pinehurst, North Carolina, Verenigde Staten, 28374
        • FirstHealth of the Carolinas-Moore Regional Hospital
      • Raleigh, North Carolina, Verenigde Staten, 27609
        • Duke Cancer Center Raleigh
      • Salisbury, North Carolina, Verenigde Staten, 28144
        • Novant Health Cancer Institute - Rowan
      • Salisbury, North Carolina, Verenigde Staten, 28144
        • Rowan Regional Medical Center
      • Statesville, North Carolina, Verenigde Staten, 28625
        • Novant Health Cancer Institute - Statesville
      • Thomasville, North Carolina, Verenigde Staten, 27360
        • Novant Health Cancer Institute - Thomasville
      • Washington, North Carolina, Verenigde Staten, 27889
        • Marion L Shepard Cancer Center - ECU Health Beaufort Hospital
      • Weaverville, North Carolina, Verenigde Staten, 28787
        • AdventHealth Infusion Center Weaverville
      • Winston-Salem, North Carolina, Verenigde Staten, 27157
        • Wake Forest University Health Sciences
      • Winston-Salem, North Carolina, Verenigde Staten, 27103
        • Novant Health Forsyth Medical Center
      • Winston-Salem, North Carolina, Verenigde Staten, 27103
        • Winston-Salem Health Care
    • North Dakota
      • Bismarck, North Dakota, Verenigde Staten, 58501
        • Sanford Bismarck Medical Center
      • Fargo, North Dakota, Verenigde Staten, 58122
        • Sanford Roger Maris Cancer Center
      • Fargo, North Dakota, Verenigde Staten, 58103
        • Essentia Health Cancer Center-South University Clinic
      • Fargo, North Dakota, Verenigde Staten, 58122
        • Sanford Broadway Medical Center
      • Fargo, North Dakota, Verenigde Staten, 58103
        • Sanford South University Medical Center
      • Jamestown, North Dakota, Verenigde Staten, 58401
        • Essentia Health - Jamestown Clinic
      • Minot, North Dakota, Verenigde Staten, 58701
        • Trinity Cancer Care Center
    • Ohio
      • Alliance, Ohio, Verenigde Staten, 44601
        • Aultman Alliance Community Hospital
      • Beachwood, Ohio, Verenigde Staten, 44122
        • UHHS-Chagrin Highlands Medical Center
      • Beavercreek, Ohio, Verenigde Staten, 45431
        • Indu and Raj Soin Medical Center
      • Belpre, Ohio, Verenigde Staten, 45714
        • Strecker Cancer Center-Belpre
      • Boardman, Ohio, Verenigde Staten, 44512
        • Saint Elizabeth Boardman Hospital
      • Canton, Ohio, Verenigde Staten, 44708
        • Cleveland Clinic Mercy Hospital
      • Canton, Ohio, Verenigde Staten, 44710
        • Aultman Health Foundation
      • Centerville, Ohio, Verenigde Staten, 45459
        • Miami Valley Hospital South
      • Centerville, Ohio, Verenigde Staten, 45459
        • Dayton Physicians LLC-Miami Valley South
      • Chardon, Ohio, Verenigde Staten, 44024
        • Geauga Hospital
      • Chillicothe, Ohio, Verenigde Staten, 45601
        • Adena Regional Medical Center
      • Cincinnati, Ohio, Verenigde Staten, 45229
        • Cincinnati Children's Hospital Medical Center
      • Cincinnati, Ohio, Verenigde Staten, 45219
        • The Christ Hospital
      • Cincinnati, Ohio, Verenigde Staten, 45220
        • Good Samaritan Hospital - Cincinnati
      • Cincinnati, Ohio, Verenigde Staten, 45242
        • Bethesda North Hospital
      • Cincinnati, Ohio, Verenigde Staten, 45242
        • Oncology Hematology Care Inc-Blue Ash
      • Cincinnati, Ohio, Verenigde Staten, 45202
        • Oncology Hematology Care Inc-Eden Park
      • Cincinnati, Ohio, Verenigde Staten, 45211
        • Oncology Hematology Care Inc-Mercy West
      • Cincinnati, Ohio, Verenigde Staten, 45230
        • Oncology Hematology Care Inc-Anderson
      • Cincinnati, Ohio, Verenigde Staten, 45236
        • Oncology Hematology Care Inc-Kenwood
      • Cincinnati, Ohio, Verenigde Staten, 45247
        • TriHealth Cancer Institute-Westside
      • Cincinnati, Ohio, Verenigde Staten, 45255
        • TriHealth Cancer Institute-Anderson
      • Cleveland, Ohio, Verenigde Staten, 44106
        • Case Western Reserve University
      • Cleveland, Ohio, Verenigde Staten, 44109
        • MetroHealth Medical Center
      • Cleveland, Ohio, Verenigde Staten, 44195
        • Cleveland Clinic Foundation
      • Columbus, Ohio, Verenigde Staten, 43214
        • Riverside Methodist Hospital
      • Columbus, Ohio, Verenigde Staten, 43210
        • Ohio State University Comprehensive Cancer Center
      • Columbus, Ohio, Verenigde Staten, 43219
        • The Mark H Zangmeister Center
      • Columbus, Ohio, Verenigde Staten, 43214
        • Columbus Oncology and Hematology Associates Inc
      • Columbus, Ohio, Verenigde Staten, 43228
        • Doctors Hospital
      • Columbus, Ohio, Verenigde Staten, 43213
        • Mount Carmel East Hospital
      • Columbus, Ohio, Verenigde Staten, 43215
        • Grant Medical Center
      • Columbus, Ohio, Verenigde Staten, 43222
        • Mount Carmel Health Center West
      • Dayton, Ohio, Verenigde Staten, 45406
        • Good Samaritan Hospital - Dayton
      • Dayton, Ohio, Verenigde Staten, 45409
        • Miami Valley Hospital
      • Dayton, Ohio, Verenigde Staten, 45415
        • Miami Valley Hospital North
      • Dayton, Ohio, Verenigde Staten, 45415
        • Dayton Physician LLC - Englewood
      • Delaware, Ohio, Verenigde Staten, 43015
        • Delaware Health Center-Grady Cancer Center
      • Delaware, Ohio, Verenigde Staten, 43015
        • Delaware Radiation Oncology
      • Delaware, Ohio, Verenigde Staten, 43015
        • Grady Memorial Hospital
      • Dublin, Ohio, Verenigde Staten, 43016
        • Dublin Methodist Hospital
      • Dublin, Ohio, Verenigde Staten, 43016
        • Columbus Oncology and Hematology Associates
      • Elyria, Ohio, Verenigde Staten, 44035
        • Mercy Cancer Center-Elyria
      • Elyria, Ohio, Verenigde Staten, 44035
        • Hematology Oncology Center Incorporated
      • Fairfield, Ohio, Verenigde Staten, 45014
        • Oncology Hematology Care Inc-Healthplex
      • Findlay, Ohio, Verenigde Staten, 45840
        • Blanchard Valley Hospital
      • Findlay, Ohio, Verenigde Staten, 45840
        • Armes Family Cancer Center
      • Findlay, Ohio, Verenigde Staten, 45840
        • Orion Cancer Care
      • Franklin, Ohio, Verenigde Staten, 45005-1066
        • Atrium Medical Center-Middletown Regional Hospital
      • Franklin, Ohio, Verenigde Staten, 45005
        • Dayton Physicians LLC-Atrium
      • Greenville, Ohio, Verenigde Staten, 45331
        • Wayne Hospital
      • Greenville, Ohio, Verenigde Staten, 45331
        • Dayton Physicians LLC-Wayne
      • Grove City, Ohio, Verenigde Staten, 43123
        • Mount Carmel Grove City Hospital
      • Kettering, Ohio, Verenigde Staten, 45429
        • Kettering Medical Center
      • Kettering, Ohio, Verenigde Staten, 45409
        • Greater Dayton Cancer Center
      • Kettering, Ohio, Verenigde Staten, 45420
        • First Dayton Cancer Care
      • Lancaster, Ohio, Verenigde Staten, 43130
        • Fairfield Medical Center
      • Lima, Ohio, Verenigde Staten, 45801
        • Saint Rita's Medical Center
      • Marietta, Ohio, Verenigde Staten, 45750
        • Marietta Memorial Hospital
      • Marion, Ohio, Verenigde Staten, 43302
        • OhioHealth Marion General Hospital
      • Maumee, Ohio, Verenigde Staten, 43537
        • Toledo Clinic Cancer Centers-Maumee
      • Maumee, Ohio, Verenigde Staten, 43537
        • Toledo Radiation Oncology at Northwest Ohio Onocolgy Center
      • Mayfield Heights, Ohio, Verenigde Staten, 44124
        • UH Seidman Cancer Center at Landerbrook Health Center
      • Mentor, Ohio, Verenigde Staten, 44060
        • UH Seidman Cancer Center at Lake Health Mentor Campus
      • Middleburg Heights, Ohio, Verenigde Staten, 44130
        • UH Seidman Cancer Center at Southwest General Hospital
      • Middletown, Ohio, Verenigde Staten, 45042
        • Dayton Physicians LLC-Signal Point
      • Mount Vernon, Ohio, Verenigde Staten, 43050
        • Knox Community Hospital
      • Newark, Ohio, Verenigde Staten, 43055
        • Licking Memorial Hospital
      • Newark, Ohio, Verenigde Staten, 43055
        • Newark Radiation Oncology
      • Oregon, Ohio, Verenigde Staten, 43616
        • Saint Charles Hospital
      • Parma, Ohio, Verenigde Staten, 44129
        • University Hospitals Parma Medical Center
      • Perrysburg, Ohio, Verenigde Staten, 43551
        • Mercy Health - Perrysburg Hospital
      • Portsmouth, Ohio, Verenigde Staten, 45662
        • Southern Ohio Medical Center
      • Sandusky, Ohio, Verenigde Staten, 44870
        • UH Seidman Cancer Center at Firelands Regional Medical Center
      • Sidney, Ohio, Verenigde Staten, 45365
        • Dayton Physicians LLC-Wilson
      • Springfield, Ohio, Verenigde Staten, 45504
        • Springfield Regional Cancer Center
      • Springfield, Ohio, Verenigde Staten, 45504
        • Springfield Regional Medical Center
      • Steubenville, Ohio, Verenigde Staten, 43952
        • Trinity's Tony Teramana Cancer Center
      • Sylvania, Ohio, Verenigde Staten, 43560
        • ProMedica Flower Hospital
      • Toledo, Ohio, Verenigde Staten, 43606
        • ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital
      • Toledo, Ohio, Verenigde Staten, 43623
        • Mercy Health - Saint Anne Hospital
      • Toledo, Ohio, Verenigde Staten, 43623
        • Toledo Clinic Cancer Centers-Toledo
      • Toledo, Ohio, Verenigde Staten, 43614
        • University of Toledo
      • Toledo, Ohio, Verenigde Staten, 43608
        • Mercy Health - Saint Vincent Hospital
      • Troy, Ohio, Verenigde Staten, 45373
        • Upper Valley Medical Center
      • Troy, Ohio, Verenigde Staten, 45373
        • Dayton Physicians LLC - Troy
      • Wadsworth, Ohio, Verenigde Staten, 44281
        • University Hospitals Sharon Health Center
      • Warren, Ohio, Verenigde Staten, 44484
        • Saint Joseph Warren Hospital
      • Westerville, Ohio, Verenigde Staten, 43081
        • Saint Ann's Hospital
      • Westlake, Ohio, Verenigde Staten, 44145
        • UH Seidman Cancer Center at Saint John Medical Center
      • Westlake, Ohio, Verenigde Staten, 44145
        • UHHS-Westlake Medical Center
      • Youngstown, Ohio, Verenigde Staten, 44501
        • Saint Elizabeth Youngstown Hospital
      • Zanesville, Ohio, Verenigde Staten, 43701
        • Genesis Healthcare System Cancer Care Center
    • Oklahoma
      • Lawton, Oklahoma, Verenigde Staten, 73505
        • Cancer Centers of Southwest Oklahoma Research
      • Oklahoma City, Oklahoma, Verenigde Staten, 73104
        • University of Oklahoma Health Sciences Center
      • Oklahoma City, Oklahoma, Verenigde Staten, 73120
        • Mercy Hospital Oklahoma City
      • Oklahoma City, Oklahoma, Verenigde Staten, 73109
        • Integris Southwest Medical Center
      • Oklahoma City, Oklahoma, Verenigde Staten, 73142
        • Integris Cancer Institute of Oklahoma
      • Tulsa, Oklahoma, Verenigde Staten, 74146
        • Oklahoma Cancer Specialists and Research Institute-Tulsa
      • Tulsa, Oklahoma, Verenigde Staten, 74133
        • Cancer Treatment Centers of America
    • Oregon
      • Baker City, Oregon, Verenigde Staten, 97814
        • Saint Alphonsus Cancer Care Center-Baker City
      • Bend, Oregon, Verenigde Staten, 97701
        • Saint Charles Health System
      • Clackamas, Oregon, Verenigde Staten, 97015
        • Clackamas Radiation Oncology Center
      • Clackamas, Oregon, Verenigde Staten, 97015
        • Providence Cancer Institute Clackamas Clinic
      • Coos Bay, Oregon, Verenigde Staten, 97420
        • Bay Area Hospital
      • Corvallis, Oregon, Verenigde Staten, 97330
        • Good Samaritan Hospital
      • Gresham, Oregon, Verenigde Staten, 97030
        • Legacy Mount Hood Medical Center
      • Newberg, Oregon, Verenigde Staten, 97132
        • Providence Newberg Medical Center
      • Ontario, Oregon, Verenigde Staten, 97914
        • Saint Alphonsus Cancer Care Center-Ontario
      • Oregon City, Oregon, Verenigde Staten, 97045
        • Providence Willamette Falls Medical Center
      • Portland, Oregon, Verenigde Staten, 97210
        • Legacy Good Samaritan Hospital and Medical Center
      • Portland, Oregon, Verenigde Staten, 97213
        • Providence Portland Medical Center
      • Portland, Oregon, Verenigde Staten, 97225
        • Providence Saint Vincent Medical Center
      • Portland, Oregon, Verenigde Staten, 97227
        • Kaiser Permanente Northwest
      • Redmond, Oregon, Verenigde Staten, 97756
        • Saint Charles Health System-Redmond
      • Tualatin, Oregon, Verenigde Staten, 97062
        • Legacy Meridian Park Hospital
    • Pennsylvania
      • Abington, Pennsylvania, Verenigde Staten, 19001
        • Jefferson Abington Hospital
      • Allentown, Pennsylvania, Verenigde Staten, 18103
        • Lehigh Valley Hospital-Cedar Crest
      • Altoona, Pennsylvania, Verenigde Staten, 16601
        • UPMC Altoona
      • Beaver, Pennsylvania, Verenigde Staten, 15009
        • UPMC-Heritage Valley Health System Beaver
      • Bethlehem, Pennsylvania, Verenigde Staten, 18017
        • Lehigh Valley Hospital - Muhlenberg
      • Bryn Mawr, Pennsylvania, Verenigde Staten, 19010
        • Bryn Mawr Hospital
      • Butler, Pennsylvania, Verenigde Staten, 16001
        • UPMC Hillman Cancer Center at Butler Health System
      • Camp Hill, Pennsylvania, Verenigde Staten, 17011
        • UPMC Camp Hill
      • Carlisle, Pennsylvania, Verenigde Staten, 17015
        • Carlisle Regional Cancer Center
      • Chadds Ford, Pennsylvania, Verenigde Staten, 19317
        • Christiana Care Health System-Concord Health Center
      • Chambersburg, Pennsylvania, Verenigde Staten, 17201
        • Chambersburg Hospital
      • Collegeville, Pennsylvania, Verenigde Staten, 19426
        • Main Line Health Center-Collegeville
      • Cranberry Township, Pennsylvania, Verenigde Staten, 16066
        • UPMC Hillman Cancer Center - Passavant - Cranberry
      • Danville, Pennsylvania, Verenigde Staten, 17822
        • Geisinger Medical Center
      • Doylestown, Pennsylvania, Verenigde Staten, 18901
        • Doylestown Hospital
      • East Stroudsburg, Pennsylvania, Verenigde Staten, 18301
        • Pocono Medical Center
      • Easton, Pennsylvania, Verenigde Staten, 18042
        • Easton Hospital
      • Ephrata, Pennsylvania, Verenigde Staten, 17522
        • Ephrata Cancer Center
      • Ephrata, Pennsylvania, Verenigde Staten, 17522
        • Ephrata Community Hospital
      • Erie, Pennsylvania, Verenigde Staten, 16505
        • UPMC Hillman Cancer Center Erie
      • Erie, Pennsylvania, Verenigde Staten, 16550
        • UPMC Hamot
      • Exton, Pennsylvania, Verenigde Staten, 19341
        • Main Line Health Center-Exton
      • Farrell, Pennsylvania, Verenigde Staten, 16121
        • UPMC Cancer Center at UPMC Horizon
      • Gettysburg, Pennsylvania, Verenigde Staten, 17325
        • Adams Cancer Center
      • Greensburg, Pennsylvania, Verenigde Staten, 15601
        • UPMC Cancer Centers - Arnold Palmer Pavilion
      • Greenville, Pennsylvania, Verenigde Staten, 16125
        • UPMC Hillman Cancer Center in Greenville/UPMC Horizon
      • Hanover, Pennsylvania, Verenigde Staten, 17331
        • WellSpan Medical Oncology and Hematology
      • Harrisburg, Pennsylvania, Verenigde Staten, 17109
        • UPMC Pinnacle Cancer Center/Community Osteopathic Campus
      • Harrisburg, Pennsylvania, Verenigde Staten, 17101
        • UPMC Pinnacle Harrisburg
      • Hazleton, Pennsylvania, Verenigde Staten, 18201
        • Geisinger Medical Center-Cancer Center Hazleton
      • Hazleton, Pennsylvania, Verenigde Staten, 18201
        • Lehigh Valley Hospital-Hazleton
      • Hershey, Pennsylvania, Verenigde Staten, 17033-0850
        • Penn State Milton S Hershey Medical Center
      • Indiana, Pennsylvania, Verenigde Staten, 15701
        • IRMC Cancer Center
      • Johnstown, Pennsylvania, Verenigde Staten, 15901
        • UPMC-Johnstown/John P. Murtha Regional Cancer Center
      • Kittanning, Pennsylvania, Verenigde Staten, 16201
        • Armstrong Center for Medicine and Health
      • Lancaster, Pennsylvania, Verenigde Staten, 17601
        • Lancaster General Ann B Barshinger Cancer Institute
      • Lancaster, Pennsylvania, Verenigde Staten, 17602
        • Lancaster General Hospital
      • Lebanon, Pennsylvania, Verenigde Staten, 17042
        • Sechler Family Cancer Center
      • Lewisburg, Pennsylvania, Verenigde Staten, 17837
        • Geisinger Medical Oncology-Lewisburg
      • Lewistown, Pennsylvania, Verenigde Staten, 17044
        • Lewistown Hospital
      • McKeesport, Pennsylvania, Verenigde Staten, 15132
        • UPMC Cancer Center at UPMC McKeesport
      • Meadowbrook, Pennsylvania, Verenigde Staten, 19046
        • Redeemer Health
      • Mechanicsburg, Pennsylvania, Verenigde Staten, 17050
        • UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion
      • Media, Pennsylvania, Verenigde Staten, 19063
        • Riddle Memorial Hospital
      • Monroeville, Pennsylvania, Verenigde Staten, 15146
        • Forbes Hospital
      • Monroeville, Pennsylvania, Verenigde Staten, 15146
        • UPMC Hillman Cancer Center - Monroeville
      • Moon Township, Pennsylvania, Verenigde Staten, 15108
        • UPMC Hillman Cancer Center in Coraopolis
      • Mount Pleasant, Pennsylvania, Verenigde Staten, 15666
        • UPMC Hillman Cancer Center - Part of Frick Hospital
      • N. Huntingdon, Pennsylvania, Verenigde Staten, 15642
        • Arnold Palmer Cancer Center Medical Oncology Norwin
      • Natrona Heights, Pennsylvania, Verenigde Staten, 15065
        • Allegheny Valley Hospital
      • Natrona Heights, Pennsylvania, Verenigde Staten, 15065
        • UPMC Cancer Center-Natrona Heights
      • New Castle, Pennsylvania, Verenigde Staten, 16105
        • UPMC Hillman Cancer Center - New Castle
      • Norristown, Pennsylvania, Verenigde Staten, 19401
        • Suburban Community Hospital and Cancer Center
      • Paoli, Pennsylvania, Verenigde Staten, 19301
        • Paoli Memorial Hospital
      • Philadelphia, Pennsylvania, Verenigde Staten, 19111
        • Fox Chase Cancer Center
      • Philadelphia, Pennsylvania, Verenigde Staten, 19107
        • Thomas Jefferson University Hospital
      • Philadelphia, Pennsylvania, Verenigde Staten, 19114
        • Jefferson Torresdale Hospital
      • Philadelphia, Pennsylvania, Verenigde Staten, 19102
        • Drexel University School of Medicine
      • Philadelphia, Pennsylvania, Verenigde Staten, 19124
        • Eastern Regional Medical Center
      • Philadelphia, Pennsylvania, Verenigde Staten, 19152
        • Nazareth Hospital
      • Phoenixville, Pennsylvania, Verenigde Staten, 19460
        • Reading Hospital McGlinn Cancer Institute at Phoenixville
      • Pittsburgh, Pennsylvania, Verenigde Staten, 15212
        • Allegheny General Hospital
      • Pittsburgh, Pennsylvania, Verenigde Staten, 15224
        • West Penn Hospital
      • Pittsburgh, Pennsylvania, Verenigde Staten, 15232
        • UPMC Hillman Cancer Center
      • Pittsburgh, Pennsylvania, Verenigde Staten, 15213
        • UPMC-Magee Womens Hospital
      • Pittsburgh, Pennsylvania, Verenigde Staten, 15215
        • UPMC-Saint Margaret
      • Pittsburgh, Pennsylvania, Verenigde Staten, 15237
        • UPMC-Passavant Hospital
      • Pittsburgh, Pennsylvania, Verenigde Staten, 15243
        • UPMC-Saint Clair Hospital Cancer Center
      • Pittsburgh, Pennsylvania, Verenigde Staten, 15215
        • Oncology Hematology Association
      • Pittsburgh, Pennsylvania, Verenigde Staten, 15219
        • UPMC-Mercy Hospital
      • Pottsville, Pennsylvania, Verenigde Staten, 17901
        • Geisinger Cancer Services-Pottsville
      • Reading, Pennsylvania, Verenigde Staten, 19605
        • Penn State Health Saint Joseph Medical Center
      • Sayre, Pennsylvania, Verenigde Staten, 18840
        • Guthrie Medical Group PC-Robert Packer Hospital
      • Scranton, Pennsylvania, Verenigde Staten, 18510
        • Community Medical Center
      • Scranton, Pennsylvania, Verenigde Staten, 18508
        • Hematology and Oncology Associates of North East Pennsylvania
      • Selinsgrove, Pennsylvania, Verenigde Staten, 17870
        • Geisinger Medical Oncology-Selinsgrove
      • Seneca, Pennsylvania, Verenigde Staten, 16346
        • UPMC Cancer Center at UPMC Northwest
      • State College, Pennsylvania, Verenigde Staten, 16801
        • Geisinger Medical Group
      • State College, Pennsylvania, Verenigde Staten, 16803
        • Mount Nittany Medical Center
      • Uniontown, Pennsylvania, Verenigde Staten, 15401
        • UPMC Cancer Center-Uniontown
      • Washington, Pennsylvania, Verenigde Staten, 15301
        • UPMC Cancer Center-Washington
      • West Chester, Pennsylvania, Verenigde Staten, 19380
        • Chester County Hospital
      • West Mifflin, Pennsylvania, Verenigde Staten, 15122
        • UPMC West Mifflin-Cancer Center Jefferson
      • West Reading, Pennsylvania, Verenigde Staten, 19611
        • Reading Hospital
      • Wilkes-Barre, Pennsylvania, Verenigde Staten, 18711
        • Geisinger Wyoming Valley/Henry Cancer Center
      • Williamsport, Pennsylvania, Verenigde Staten, 17701
        • UPMC Susquehanna
      • Williamsport, Pennsylvania, Verenigde Staten, 17754
        • Divine Providence Hospital
      • Willow Grove, Pennsylvania, Verenigde Staten, 19090
        • Asplundh Cancer Pavilion
      • Wynnewood, Pennsylvania, Verenigde Staten, 19096
        • Lankenau Medical Center
      • York, Pennsylvania, Verenigde Staten, 17403
        • WellSpan Health-York Cancer Center
      • York, Pennsylvania, Verenigde Staten, 17403
        • WellSpan Health-York Hospital
      • York, Pennsylvania, Verenigde Staten, 17403
        • Cancer Care Associates of York
      • York, Pennsylvania, Verenigde Staten, 17408
        • UPMC Memorial
    • Rhode Island
      • Newport, Rhode Island, Verenigde Staten, 02840
        • Newport Hospital
      • Providence, Rhode Island, Verenigde Staten, 02903
        • Rhode Island Hospital
      • Providence, Rhode Island, Verenigde Staten, 02905
        • Women and Infants Hospital
      • Providence, Rhode Island, Verenigde Staten, 02906
        • Miriam Hospital
      • Westerly, Rhode Island, Verenigde Staten, 02891
        • Smilow Cancer Hospital Care Center - Westerly
    • South Carolina
      • Anderson, South Carolina, Verenigde Staten, 29621
        • AnMed Health Cancer Center
      • Beaufort, South Carolina, Verenigde Staten, 29902
        • Beaufort Memorial Hospital
      • Boiling Springs, South Carolina, Verenigde Staten, 29316
        • Prisma Health Cancer Institute - Spartanburg
      • Charleston, South Carolina, Verenigde Staten, 29425
        • Medical University of South Carolina
      • Charleston, South Carolina, Verenigde Staten, 29401
        • Roper Hospital
      • Charleston, South Carolina, Verenigde Staten, 29406
        • Lowcountry Hematology Oncology PA-North Charleston
      • Charleston, South Carolina, Verenigde Staten, 29414
        • Bon Secours Saint Francis Hospital
      • Charleston, South Carolina, Verenigde Staten, 29403
        • Charleston Oncology - Roper
      • Charleston, South Carolina, Verenigde Staten, 29414
        • Charleston Oncology - Saint Francis
      • Charleston, South Carolina, Verenigde Staten, 29414
        • Lowcountry Oncology Associates - West Ashley
      • Easley, South Carolina, Verenigde Staten, 29640
        • Prisma Health Cancer Institute - Easley
      • Florence, South Carolina, Verenigde Staten, 29506
        • McLeod Regional Medical Center
      • Gaffney, South Carolina, Verenigde Staten, 29341
        • Gibbs Cancer Center-Gaffney
      • Georgetown, South Carolina, Verenigde Staten, 29440
        • Tidelands Georgetown Memorial Hospital
      • Greenville, South Carolina, Verenigde Staten, 29605
        • Prisma Health Cancer Institute - Faris
      • Greenville, South Carolina, Verenigde Staten, 29607
        • Saint Francis Cancer Center
      • Greenville, South Carolina, Verenigde Staten, 29615
        • Prisma Health Cancer Institute - Eastside
      • Greenville, South Carolina, Verenigde Staten, 29605
        • Prisma Health Cancer Institute - Butternut
      • Greenville, South Carolina, Verenigde Staten, 29601
        • Saint Francis Hospital
      • Greenville, South Carolina, Verenigde Staten, 29605
        • Prisma Health Greenville Memorial Hospital
      • Greenville, South Carolina, Verenigde Staten, 29601
        • Greenville Health System Cancer Institute-Andrews
      • Greenwood, South Carolina, Verenigde Staten, 29646
        • Self Regional Healthcare
      • Greer, South Carolina, Verenigde Staten, 29650
        • Prisma Health Cancer Institute - Greer
      • Greer, South Carolina, Verenigde Staten, 29651
        • Gibbs Cancer Center-Pelham
      • Hilton Head Island, South Carolina, Verenigde Staten, 29926
        • The Radiation Oncology Center-Hilton Head/Bluffton
      • Hilton Head Island, South Carolina, Verenigde Staten, 29926-3827
        • South Carolina Cancer Specialists PC
      • Mt. Pleasant, South Carolina, Verenigde Staten, 29464
        • Lowcountry Oncology Associates - Mount Pleasant
      • Seneca, South Carolina, Verenigde Staten, 29672
        • Prisma Health Cancer Institute - Seneca
      • Spartanburg, South Carolina, Verenigde Staten, 29303
        • Spartanburg Medical Center
      • Spartanburg, South Carolina, Verenigde Staten, 29307
        • Spartanburg Medical Center - Mary Black Campus
      • Spartanburg, South Carolina, Verenigde Staten, 29303
        • North Grove Medical Park
      • Union, South Carolina, Verenigde Staten, 29379
        • SMC Center for Hematology Oncology Union
    • South Dakota
      • Aberdeen, South Dakota, Verenigde Staten, 57401
        • Avera Cancer Institute-Aberdeen
      • Rapid City, South Dakota, Verenigde Staten, 57701
        • Rapid City Regional Hospital
      • Sioux Falls, South Dakota, Verenigde Staten, 57105
        • Avera Cancer Institute
      • Sioux Falls, South Dakota, Verenigde Staten, 57117-5134
        • Sanford USD Medical Center - Sioux Falls
      • Sioux Falls, South Dakota, Verenigde Staten, 57104
        • Sanford Cancer Center Oncology Clinic
    • Tennessee
      • Chattanooga, Tennessee, Verenigde Staten, 37404
        • Memorial Hospital
      • Collierville, Tennessee, Verenigde Staten, 38017
        • Integrity Oncology PLLC-Collierville
      • Cookeville, Tennessee, Verenigde Staten, 38501
        • Cookeville Regional Medical Center
      • Franklin, Tennessee, Verenigde Staten, 37067
        • Vanderbilt-Ingram Cancer Center Cool Springs
      • Hixson, Tennessee, Verenigde Staten, 37343
        • Pulmonary Medicine Center of Chattanooga-Hixson
      • Knoxville, Tennessee, Verenigde Staten, 37909
        • Tennessee Cancer Specialists-Dowell Springs
      • Knoxville, Tennessee, Verenigde Staten, 37916
        • Covenant Health Cancer Centers
      • Knoxville, Tennessee, Verenigde Staten, 37932
        • Covenant Health Cancer Centers - West
      • Maryville, Tennessee, Verenigde Staten, 37804
        • Covenant Health Oncology Group - Maryville
      • Memphis, Tennessee, Verenigde Staten, 38120
        • Baptist Memorial Hospital and Cancer Center-Memphis
      • Nashville, Tennessee, Verenigde Staten, 37232
        • Vanderbilt University/Ingram Cancer Center
      • Nashville, Tennessee, Verenigde Staten, 37204
        • Vanderbilt Breast Center at One Hundred Oaks
      • Nashville, Tennessee, Verenigde Staten, 37208
        • Meharry Medical College
      • Oak Ridge, Tennessee, Verenigde Staten, 37830
        • Covenant Health Oncology Group - Oak Ridge
      • Ooltewah, Tennessee, Verenigde Staten, 37363
        • Memorial GYN Plus
    • Texas
      • Austin, Texas, Verenigde Staten, 78701
        • Dell Seton Medical Center at The University of Texas
      • Bryan, Texas, Verenigde Staten, 77802
        • Saint Joseph Regional Cancer Center
      • Conroe, Texas, Verenigde Staten, 77384
        • UT MD Anderson - The Woodlands
      • Dallas, Texas, Verenigde Staten, 75235
        • Parkland Memorial Hospital
      • Dallas, Texas, Verenigde Staten, 75390
        • UT Southwestern/Simmons Cancer Center-Dallas
      • Dallas, Texas, Verenigde Staten, 75246
        • Baylor University Medical Center
      • Fort Worth, Texas, Verenigde Staten, 76104
        • UT Southwestern/Simmons Cancer Center-Fort Worth
      • Houston, Texas, Verenigde Staten, 77030
        • UT MD Anderson Cancer Center
      • Houston, Texas, Verenigde Staten, 77030
        • Houston Methodist Hospital
      • Houston, Texas, Verenigde Staten, 77030
        • Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center
      • Houston, Texas, Verenigde Staten, 77030
        • Memorial Hermann Texas Medical Center
      • Houston, Texas, Verenigde Staten, 77079
        • UT MD Anderson - West Houston
      • Humble, Texas, Verenigde Staten, 77338
        • Memorial Hermann Northeast Hospital
      • League City, Texas, Verenigde Staten, 77573
        • UT MD Anderson - League City
      • Lubbock, Texas, Verenigde Staten, 79410
        • Covenant Medical Center-Lakeside
      • Richardson, Texas, Verenigde Staten, 75080
        • UT Southwestern Clinical Center at Richardson/Plano
      • San Antonio, Texas, Verenigde Staten, 78229
        • University Hospital
      • San Antonio, Texas, Verenigde Staten, 78229
        • University of Texas Health Science Center at San Antonio
      • San Antonio, Texas, Verenigde Staten, 78229
        • Methodist Children's Hospital of South Texas
      • Sugar Land, Texas, Verenigde Staten, 77478
        • UT MD Anderson - Sugar Land
      • The Woodlands, Texas, Verenigde Staten, 77380
        • Memorial Hermann The Woodlands Hospital
    • Utah
      • American Fork, Utah, Verenigde Staten, 84003
        • American Fork Hospital / Huntsman Intermountain Cancer Center
      • Cedar City, Utah, Verenigde Staten, 84720
        • Sandra L Maxwell Cancer Center
      • Farmington, Utah, Verenigde Staten, 84025
        • Farmington Health Center
      • Logan, Utah, Verenigde Staten, 84321
        • Logan Regional Hospital
      • Murray, Utah, Verenigde Staten, 84107
        • Intermountain Medical Center
      • Ogden, Utah, Verenigde Staten, 84403
        • McKay-Dee Hospital Center
      • Provo, Utah, Verenigde Staten, 84604
        • Utah Valley Regional Medical Center
      • Riverton, Utah, Verenigde Staten, 84065
        • Riverton Hospital
      • Salt Lake City, Utah, Verenigde Staten, 84112
        • Huntsman Cancer Institute/University of Utah
      • Salt Lake City, Utah, Verenigde Staten, 84106
        • Utah Cancer Specialists-Salt Lake City
      • Salt Lake City, Utah, Verenigde Staten, 84143
        • LDS Hospital
      • Salt Lake City, Utah, Verenigde Staten, 84106
        • University of Utah Sugarhouse Health Center
      • South Jordan, Utah, Verenigde Staten, 84009
        • South Jordan Health Center
      • St. George, Utah, Verenigde Staten, 84770
        • Saint George Regional Medical Center
    • Vermont
      • Berlin Corners, Vermont, Verenigde Staten, 05602
        • Central Vermont Medical Center/National Life Cancer Treatment
      • Burlington, Vermont, Verenigde Staten, 05401
        • University of Vermont Medical Center
      • Burlington, Vermont, Verenigde Staten, 05405
        • University of Vermont and State Agricultural College
      • Saint Johnsbury, Vermont, Verenigde Staten, 05819
        • Dartmouth Cancer Center - North
    • Virginia
      • Danville, Virginia, Verenigde Staten, 24541
        • Danville Regional Medical Center
      • Fairfax, Virginia, Verenigde Staten, 22031
        • Inova Schar Cancer Institute
      • Fairfax, Virginia, Verenigde Staten, 22033
        • Inova Fair Oaks Hospital
      • Falls Church, Virginia, Verenigde Staten, 22042
        • Inova Fairfax Hospital
      • Fishersville, Virginia, Verenigde Staten, 22939
        • Augusta Health Center for Cancer and Blood Disorders
      • Fredericksburg, Virginia, Verenigde Staten, 22408
        • Hematology Oncology Associates of Fredericksburg Inc
      • Lynchburg, Virginia, Verenigde Staten, 24501
        • Centra Alan B Pearson Regional Cancer Center
      • Martinsville, Virginia, Verenigde Staten, 24112
        • Sovah Health Martinsville
      • Mechanicsville, Virginia, Verenigde Staten, 23116
        • Bon Secours Memorial Regional Medical Center
      • Midlothian, Virginia, Verenigde Staten, 23114
        • Bon Secours Saint Francis Medical Center
      • Midlothian, Virginia, Verenigde Staten, 23113
        • Bon Secours Westchester Emergency Center
      • Norfolk, Virginia, Verenigde Staten, 23507
        • Children's Hospital of The King's Daughters
      • Richmond, Virginia, Verenigde Staten, 23235
        • VCU Massey Cancer Center at Stony Point
      • Richmond, Virginia, Verenigde Staten, 23229
        • Virginia Cancer Institute
      • Richmond, Virginia, Verenigde Staten, 23226
        • Bon Secours Saint Mary's Hospital
      • Richmond, Virginia, Verenigde Staten, 23230
        • Bon Secours Cancer Institute at Reynolds Crossing
      • Richmond, Virginia, Verenigde Staten, 23298
        • VCU Massey Comprehensive Cancer Center
    • Washington
      • Aberdeen, Washington, Verenigde Staten, 98520
        • Providence Regional Cancer System-Aberdeen
      • Anacortes, Washington, Verenigde Staten, 98221
        • Cancer Care Center at Island Hospital
      • Auburn, Washington, Verenigde Staten, 98001
        • MultiCare Auburn Medical Center
      • Bainbridge Island, Washington, Verenigde Staten, 98110
        • Virginia Mason Bainbridge Island Medical Center
      • Bellevue, Washington, Verenigde Staten, 98004
        • Overlake Medical Center
      • Bellingham, Washington, Verenigde Staten, 98225
        • PeaceHealth Saint Joseph Medical Center
      • Burien, Washington, Verenigde Staten, 98166
        • Saint Anne Hospital
      • Centralia, Washington, Verenigde Staten, 98531
        • Providence Regional Cancer System-Centralia
      • Edmonds, Washington, Verenigde Staten, 98026
        • Swedish Cancer Institute-Edmonds
      • Enumclaw, Washington, Verenigde Staten, 98022
        • Saint Elizabeth Hospital
      • Everett, Washington, Verenigde Staten, 98201
        • Providence Regional Cancer Partnership
      • Federal Way, Washington, Verenigde Staten, 98002
        • Virginia Mason Federal Way Medical Center
      • Federal Way, Washington, Verenigde Staten, 98003
        • Saint Francis Hospital
      • Gig Harbor, Washington, Verenigde Staten, 98332
        • Tacoma/Valley Radiation Oncology Centers-Gig Harbor
      • Gig Harbor, Washington, Verenigde Staten, 98335
        • MultiCare Gig Harbor Medical Park
      • Issaquah, Washington, Verenigde Staten, 98029
        • Swedish Cancer Institute-Issaquah
      • Kennewick, Washington, Verenigde Staten, 99336
        • Kadlec Clinic Hematology and Oncology
      • Kennewick, Washington, Verenigde Staten, 99336
        • Northwest Cancer Clinic
      • Lacey, Washington, Verenigde Staten, 98503
        • Providence Regional Cancer System-Lacey
      • Lakewood, Washington, Verenigde Staten, 98499
        • Saint Clare Hospital
      • Longview, Washington, Verenigde Staten, 98632
        • PeaceHealth Saint John Medical Center
      • Lynnwood, Washington, Verenigde Staten, 98036
        • Virginia Mason Lynnwood Medical Center
      • Mount Vernon, Washington, Verenigde Staten, 98274
        • Skagit Valley Hospital
      • Mount Vernon, Washington, Verenigde Staten, 98274
        • Skagit Regional Health Cancer Care Center
      • Port Townsend, Washington, Verenigde Staten, 98368
        • Jefferson Healthcare
      • Poulsbo, Washington, Verenigde Staten, 98370
        • Harrison HealthPartners Hematology and Oncology-Poulsbo
      • Poulsbo, Washington, Verenigde Staten, 98370
        • Peninsula Cancer Center
      • Puyallup, Washington, Verenigde Staten, 98372
        • MultiCare Good Samaritan Hospital
      • Puyallup, Washington, Verenigde Staten, 98372
        • Tacoma/Valley Radiation Oncology Centers-Puyallup
      • Renton, Washington, Verenigde Staten, 98055
        • Valley Medical Center
      • Seattle, Washington, Verenigde Staten, 98101
        • Virginia Mason Medical Center
      • Seattle, Washington, Verenigde Staten, 98107
        • Swedish Medical Center-Ballard Campus
      • Seattle, Washington, Verenigde Staten, 98122
        • Swedish Medical Center-First Hill
      • Seattle, Washington, Verenigde Staten, 98195
        • University of Washington Medical Center - Montlake
      • Seattle, Washington, Verenigde Staten, 98112
        • Kaiser Permanente Washington
      • Seattle, Washington, Verenigde Staten, 98104
        • Minor and James Medical PLLC
      • Seattle, Washington, Verenigde Staten, 98104
        • Pacific Gynecology Specialists
      • Seattle, Washington, Verenigde Staten, 98122-5711
        • Swedish Medical Center-Cherry Hill
      • Seattle, Washington, Verenigde Staten, 98109
        • Fred Hutchinson Cancer Center
      • Sedro-Woolley, Washington, Verenigde Staten, 98284
        • PeaceHealth United General Medical Center
      • Shelton, Washington, Verenigde Staten, 98584
        • Providence Regional Cancer System-Shelton
      • Silverdale, Washington, Verenigde Staten, 98383
        • Saint Joseph Medical Center Hematology and Oncology - Silverdale
      • Spokane, Washington, Verenigde Staten, 99204
        • Providence Sacred Heart Medical Center and Children's Hospital
      • Spokane, Washington, Verenigde Staten, 99218
        • Evergreen Hematology and Oncology PS
      • Spokane, Washington, Verenigde Staten, 99208
        • Spokane Valley Cancer Center-Mayfair
      • Spokane, Washington, Verenigde Staten, 99204
        • MultiCare Deaconess Cancer and Blood Specialty Center - Downtown
      • Spokane, Washington, Verenigde Staten, 99218
        • MultiCare Deaconess Cancer and Blood Specialty Center - North
      • Spokane, Washington, Verenigde Staten, 99216
        • Spokane Valley Cancer Center-Mission
      • Spokane Valley, Washington, Verenigde Staten, 99216
        • MultiCare Deaconess Cancer and Blood Specialty Center - Valley
      • Tacoma, Washington, Verenigde Staten, 98405
        • Mary Bridge Children's Hospital and Health Center
      • Tacoma, Washington, Verenigde Staten, 98405
        • Northwest Medical Specialties PLLC
      • Tacoma, Washington, Verenigde Staten, 98405
        • MultiCare Tacoma General Hospital
      • Tacoma, Washington, Verenigde Staten, 98405
        • Tacoma/Valley Radiation Oncology Centers-Saint Joe's
      • Tacoma, Washington, Verenigde Staten, 97405
        • Tacoma/Valley Radiation Oncology Centers-Jackson Hall
      • Tacoma, Washington, Verenigde Staten, 98405
        • Franciscan Research Center-Northwest Medical Plaza
      • Vancouver, Washington, Verenigde Staten, 98686
        • Legacy Salmon Creek Hospital
      • Vancouver, Washington, Verenigde Staten, 98664
        • PeaceHealth Southwest Medical Center
      • Vancouver, Washington, Verenigde Staten, 98684
        • Legacy Cancer Institute Medical Oncology and Day Treatment
      • Walla Walla, Washington, Verenigde Staten, 99362
        • Providence Saint Mary Regional Cancer Center
      • Wenatchee, Washington, Verenigde Staten, 98801
        • Wenatchee Valley Hospital and Clinics
      • Yakima, Washington, Verenigde Staten, 98902
        • North Star Lodge Cancer Center at Yakima Valley Memorial Hospital
      • Yelm, Washington, Verenigde Staten, 98597
        • Providence Regional Cancer System-Yelm
    • West Virginia
      • Bridgeport, West Virginia, Verenigde Staten, 26330
        • United Hospital Center
      • Charleston, West Virginia, Verenigde Staten, 25304
        • Vandalia Health/CAMC Institute for Academic Medicine
      • Huntington, West Virginia, Verenigde Staten, 25701
        • Edwards Comprehensive Cancer Center
      • Martinsburg, West Virginia, Verenigde Staten, 25401
        • WVUH-Berkely Medical Center
      • Morgantown, West Virginia, Verenigde Staten, 26506
        • West Virginia University Healthcare
      • Morgantown, West Virginia, Verenigde Staten, 26505
        • Monongalia Hospital
      • Parkersburg, West Virginia, Verenigde Staten, 26101
        • Camden Clark Medical Center
      • Wheeling, West Virginia, Verenigde Staten, 26003
        • Wheeling Hospital/Schiffler Cancer Center
    • Wisconsin
      • Antigo, Wisconsin, Verenigde Staten, 54409
        • Aspirus Cancer Care-Antigo-Volm Cancer Center
      • Appleton, Wisconsin, Verenigde Staten, 54915
        • Ascension Northeast Wisconsin-Saint Elizabeth Cancer Center-Appleton
      • Ashland, Wisconsin, Verenigde Staten, 54806
        • Duluth Clinic Ashland
      • Ashland, Wisconsin, Verenigde Staten, 54806
        • Northwest Wisconsin Cancer Center
      • Brookfield, Wisconsin, Verenigde Staten, 53045
        • Ascension Southeast Wisconsin Hospital-Elmbrook Campus-Brookfield
      • Burlington, Wisconsin, Verenigde Staten, 53105
        • Aurora Cancer Care-Southern Lakes VLCC
      • Chilton, Wisconsin, Verenigde Staten, 53014
        • Ascension Calumet Hospital-Chilton
      • Chippewa Falls, Wisconsin, Verenigde Staten, 54729
        • Marshfield Clinic-Chippewa Center
      • Cudahy, Wisconsin, Verenigde Staten, 53110
        • Aurora Saint Luke's South Shore
      • Eau Claire, Wisconsin, Verenigde Staten, 54701
        • Marshfield Medical Center-EC Cancer Center
      • Eau Claire, Wisconsin, Verenigde Staten, 54701
        • HSHS Sacred Heart Hospital
      • Eau Claire, Wisconsin, Verenigde Staten, 54701
        • Marshfield Clinic Cancer Center at Sacred Heart
      • Fond du Lac, Wisconsin, Verenigde Staten, 54937
        • Aurora Health Center-Fond du Lac
      • Franklin, Wisconsin, Verenigde Staten, 53132
        • Ascension Southeast Wisconsin Hospital - Franklin
      • Franklin, Wisconsin, Verenigde Staten, 53132
        • Reiman Cancer Center-Ascension Wisconsin Health Center-Rawson
      • Germantown, Wisconsin, Verenigde Staten, 53022
        • Aurora Health Care Germantown Health Center
      • Grafton, Wisconsin, Verenigde Staten, 53024
        • Aurora Cancer Care-Grafton
      • Green Bay, Wisconsin, Verenigde Staten, 54311
        • Aurora BayCare Medical Center
      • Green Bay, Wisconsin, Verenigde Staten, 54301
        • Saint Vincent Hospital Cancer Center Green Bay
      • Green Bay, Wisconsin, Verenigde Staten, 54303
        • Saint Vincent Hospital Cancer Center at Saint Mary's
      • Janesville, Wisconsin, Verenigde Staten, 53548
        • Mercyhealth Hospital and Cancer Center - Janesville
      • Kenosha, Wisconsin, Verenigde Staten, 53142
        • Aurora Cancer Care-Kenosha South
      • La Crosse, Wisconsin, Verenigde Staten, 54601
        • Gundersen Lutheran Medical Center
      • Ladysmith, Wisconsin, Verenigde Staten, 54848
        • Marshfield Medical Center - Ladysmith
      • Madison, Wisconsin, Verenigde Staten, 53792
        • University of Wisconsin Carbone Cancer Center - University Hospital
      • Manitowoc, Wisconsin, Verenigde Staten, 54221
        • Holy Family Memorial Hospital
      • Marinette, Wisconsin, Verenigde Staten, 54143
        • Aurora Bay Area Medical Group-Marinette
      • Marshfield, Wisconsin, Verenigde Staten, 54449
        • Marshfield Medical Center-Marshfield
      • Marshfield, Wisconsin, Verenigde Staten, 54449
        • Marshfield Medical Center
      • Medford, Wisconsin, Verenigde Staten, 54451
        • Aspirus Medford Hospital
      • Mequon, Wisconsin, Verenigde Staten, 53097
        • Ascension Columbia Saint Mary's Hospital-Ozaukee Campus-Mequon
      • Milwaukee, Wisconsin, Verenigde Staten, 53226
        • Medical College of Wisconsin
      • Milwaukee, Wisconsin, Verenigde Staten, 53209
        • Aurora Cancer Care-Milwaukee
      • Milwaukee, Wisconsin, Verenigde Staten, 53215
        • Aurora Saint Luke's Medical Center
      • Milwaukee, Wisconsin, Verenigde Staten, 53233
        • Aurora Sinai Medical Center
      • Milwaukee, Wisconsin, Verenigde Staten, 53210
        • Ascension Southeast Wisconsin Hospital-Saint Joseph-Milwaukee
      • Milwaukee, Wisconsin, Verenigde Staten, 53211
        • Ascension Columbia Saint Mary's Hospital-Milwaukee Campus
      • Milwaukee, Wisconsin, Verenigde Staten, 53215
        • Ascension Saint Francis Hospital-Milwaukee
      • Minocqua, Wisconsin, Verenigde Staten, 54548
        • Marshfield Medical Center - Minocqua
      • Mukwonago, Wisconsin, Verenigde Staten, 53149
        • ProHealth D N Greenwald Center
      • New Richmond, Wisconsin, Verenigde Staten, 54017
        • Cancer Center of Western Wisconsin
      • Oconomowoc, Wisconsin, Verenigde Staten, 53066
        • ProHealth Oconomowoc Memorial Hospital
      • Oconto Falls, Wisconsin, Verenigde Staten, 54154
        • Saint Vincent Hospital Cancer Center at Oconto Falls
      • Oshkosh, Wisconsin, Verenigde Staten, 54904
        • Vince Lombardi Cancer Clinic - Oshkosh
      • Oshkosh, Wisconsin, Verenigde Staten, 54904
        • Ascension Northeast Wisconsin-Mercy Hospital-Oshkosh
      • Racine, Wisconsin, Verenigde Staten, 53406
        • Aurora Cancer Care-Racine
      • Racine, Wisconsin, Verenigde Staten, 53405
        • Ascension All Saints Hospital-Spring Street-Racine
      • Rhinelander, Wisconsin, Verenigde Staten, 54501
        • Saint Mary's Hospital
      • Rhinelander, Wisconsin, Verenigde Staten, 54501
        • Aspirus Cancer Care-Rhinelander-James Beck Cancer Center
      • Rice Lake, Wisconsin, Verenigde Staten, 54868
        • Marshfield Medical Center-Rice Lake
      • Rice Lake, Wisconsin, Verenigde Staten, 54868
        • Lakeview Medical Center-Marshfield Clinic
      • Sheboygan, Wisconsin, Verenigde Staten, 53081
        • Vince Lombardi Cancer Clinic-Sheboygan
      • Sheboygan, Wisconsin, Verenigde Staten, 53081
        • HSHS Saint Nicholas Hospital
      • Stevens Point, Wisconsin, Verenigde Staten, 54482
        • Marshfield Medical Center-River Region at Stevens Point
      • Stevens Point, Wisconsin, Verenigde Staten, 54481
        • Aspirus Cancer Care - Stevens Point
      • Sturgeon Bay, Wisconsin, Verenigde Staten, 54235-1495
        • Saint Vincent Hospital Cancer Center at Sturgeon Bay
      • Summit, Wisconsin, Verenigde Staten, 53066
        • Aurora Medical Center in Summit
      • Two Rivers, Wisconsin, Verenigde Staten, 54241
        • Vince Lombardi Cancer Clinic-Two Rivers
      • Waukesha, Wisconsin, Verenigde Staten, 53188
        • UW Cancer Center at ProHealth Care
      • Waukesha, Wisconsin, Verenigde Staten, 53188
        • ProHealth Waukesha Memorial Hospital
      • Waukesha, Wisconsin, Verenigde Staten, 53188
        • Aurora Cancer Care-Waukesha
      • Wausau, Wisconsin, Verenigde Staten, 54401
        • Marshfield Clinic-Wausau Center
      • Wausau, Wisconsin, Verenigde Staten, 54401
        • Aspirus Cancer Care-Wausau
      • Wauwatosa, Wisconsin, Verenigde Staten, 53226
        • Aurora Cancer Care-Milwaukee West
      • Wauwatosa, Wisconsin, Verenigde Staten, 53226
        • Ascension Southeast Wisconsin Hospital-Mayfair Road-Wauwatosa
      • West Allis, Wisconsin, Verenigde Staten, 53227
        • Aurora West Allis Medical Center
      • Weston, Wisconsin, Verenigde Staten, 54476
        • Marshfield Medical Center - Weston
      • Wisconsin Rapids, Wisconsin, Verenigde Staten, 54494
        • Aspirus Cancer Care - Wisconsin Rapids
      • Wisconsin Rapids, Wisconsin, Verenigde Staten, 54494
        • Marshfield Clinic - Wisconsin Rapids Center
    • Wyoming
      • Cheyenne, Wyoming, Verenigde Staten, 82001
        • Cheyenne Regional Medical Center-West
      • Cody, Wyoming, Verenigde Staten, 82414
        • Big Horn Basin Cancer Center
      • Cody, Wyoming, Verenigde Staten, 82414
        • Billings Clinic-Cody
      • Sheridan, Wyoming, Verenigde Staten, 82801
        • Welch Cancer Center

Deelname Criteria

Onderzoekers zoeken naar mensen die aan een bepaalde beschrijving voldoen, de zogenaamde geschiktheidscriteria. Enkele voorbeelden van deze criteria zijn iemands algemene gezondheidstoestand of eerdere behandelingen.

Geschiktheidscriteria

Geschiktheidscriteria

De belangrijkste eisen waaraan mensen die willen deelnemen aan een klinische studie moeten voldoen of de eigenschappen die ze moeten hebben. Geschiktheidscriteria bestaan ​​uit zowel inclusiecriteria (die vereist zijn voor een persoon om deel te nemen aan het onderzoek) als uitsluitingscriteria (die voorkomen dat een persoon deelneemt). Soorten geschiktheidscriteria zijn onder meer of een onderzoek gezonde vrijwilligers accepteert, leeftijds- of leeftijdsgroepvereisten heeft, of wordt beperkt door geslacht.

Leeftijden die in aanmerking komen voor studie

18 jaar en ouder (Volwassen, Oudere volwassene)

Accepteert gezonde vrijwilligers

Nee

Geslachten die in aanmerking komen voor studie

Allemaal

Beschrijving

Inclusion Criteria:

  • ELIGIBILITY CRITERIA FOR SCREENING BIOPSY (STEP 0)

  • Patients must be >= 18 years of age. Because no dosing or adverse event data are currently available on the use of study investigational agents in patients < 18 years of age, children are excluded from this study

  • Patients of childbearing potential must have a negative serum pregnancy test within 2 weeks prior to registration; patients that are pregnant or breast feeding are excluded; a patient of childbearing potential is anyone, regardless of whether they have undergone tubal ligation, who meets the following criteria:

    • Has achieved menarche at some point
    • Has not undergone a hysterectomy or bilateral oophorectomy; or
    • Has not been naturally postmenopausal for at least 24 consecutive months (i.e., has had menses at any time in the preceding 24 consecutive months)

  • Patients must not expect to conceive or father children by using accepted and effective method(s) of contraception or by abstaining from sexual intercourse prior to study entry, for the duration of study participation, and for 4 months after completion of study; should a patient or partner of the patient become pregnant or suspect a pregnancy while participating in this study, the treating physician should be informed immediately

  • Patients must have histologically documented solid tumors or histologically confirmed diagnosis of lymphoma or multiple myeloma requiring therapy and meet one of the following criteria:

    • Patients must have progressed following at least one line of standard systemic therapy and there must not be other approval/standard therapy available that has been shown to prolong overall survival (i.e. in a randomized trial against another standard treatment or by comparison to historical controls); patients who cannot receive other standard therapy that has been shown to prolong overall survival due to medical issues will be eligible, if other eligibility criteria are met; if the patient is currently receiving therapy, the clinician must have assessed that the current therapy is no longer benefitting the patient prior to enrolling on MATCH, regardless of whether it is considered standard OR
    • Patients for whose disease no standard treatment exists that has been shown to prolong overall survival
    • NOTE: No other prior malignancy is allowed except for the following:
    • Adequately treated basal cell or squamous cell skin cancer
    • In situ cervical cancer
    • Adequately treated stage I or II cancer from which the patient is currently in complete remission
    • Any other cancer from which the patient has been disease-free for 5 years

  • Patients must have measurable disease

  • Patients must meet the criteria below

    • Tumor tissue for the confirmation of "rare variant" by the MATCH assay is to be submitted, preferably from the same time of collection as that used to determine patient candidacy for treatment arm assignment

      • Registration to Step 0 must occur after stopping prior systemic anti-cancer therapy. There is no specific duration for which patients must be off treatment prior to registration to Step 0, as long as all eligibility criteria are met

      • Patients may have received other non-targeted, immunotherapy or targeted treatment between the prior genetic testing at the outside lab and registration to Step 0. The decision to stop such treatment in favor of participation in MATCH, if no further clinical benefit is expected, is per the treating physician's discretion. Documentation of a lack of response to the prior treatment is not required in these cases

      • Patients with an applicable "rare variant" must be able to meet the eligibility criteria for the appropriate subprotocols within 4 weeks following notification of treatment assignment

      • Patient meets one of the following criteria:

        • Patient is a candidate for Z1M based on local Clinical Laboratory Improvement Act (CLIA) assessment of mismatch repair deficiency (MMRd) by immunohistochemistry (IHC) or microsatellite instability (MSI) status by polymerase chain reaction (PCR), adequate tumor tissue is available for submission for mandatory central screening IHC and the patient will be able to meet the eligibility criteria for Z1M within 4 weeks following notification of treatment assignment OR
        • The sites have received results from one of the designated outside laboratories indicating a "rare variant" that is an actionable Mutation of Interest (aMOI) for specific select subprotocols

    • NOTE: There is no particular window of time after receiving the sequencing report notification of potential eligibility from an outside lab in which the patient must be registered to Step 0, but treatment slots will be assigned on a first come, first serve basis to those who do register to Step 0, and are not held for those notified of potential eligibility who do not register to Step 0

    • NOTE: Treatment assignment (and the start of the associated deadline for Step 1 registration) may occur shortly after Step 0 registration. Note that certain "rare variant" arms require submission of archival tissue for central IHC testing to determine treatment assignment. For those arms, adequate tissue for the central IHC is required to be available for submission

    • NOTE: Other potential aMOIs that would be eligibility criteria for "NON RARE" arms, as determined by the designated laboratories, are not applicable for this process in MATCH

  • Patient must not require the use of full dose coumarin-derivative anticoagulants such as warfarin; low molecular weight heparin is permitted for prophylactic or therapeutic use; factor X inhibitors are permitted

    • NOTE: Warfarin may not be started while enrolled in the EAY131 study
    • Stopping the anticoagulation for biopsy should be per site standard operating procedure (SOP)

  • Patients must have Eastern Cooperative Oncology Group (ECOG) performance status =< 1 and a life expectancy of at least 3 months

  • Patients must not currently be receiving any other investigational agents

  • Patients must not have any uncontrolled intercurrent illness including, but not limited to:

    • Symptomatic congestive heart failure (New York Heart Association [NYHA] classification of III/IV)
    • Unstable angina pectoris or coronary angioplasty, or stenting within 6 months prior to registration to Step 0, 2, 4, 6
    • Cardiac arrhythmia (ongoing cardiac dysrhythmias of National Cancer Institute [NCI] Common Terminology Criteria for Adverse Events [CTCAE] version [v]4 grade >= 2)
    • Psychiatric illness/social situations that would limit compliance with study requirements
    • Intra-cardiac defibrillators
    • Known cardiac metastases
    • Abnormal cardiac valve morphology (>= grade 2) documented by echocardiogram (ECHO) (as clinically indicated); (subjects with grade 1 abnormalities [i.e., mild regurgitation/stenosis] can be entered on study); subjects with moderate valvular thickening should not be entered on study
    • NOTE: To receive an agent, patient must not have any uncontrolled intercurrent illness such as ongoing or active infection; patients with infections unlikely to be resolved within 2 weeks following screening should not be considered for the trial

  • Patients must be able to swallow tablets or capsules; a patient with any gastrointestinal disease that would impair ability to swallow, retain, or absorb drug is not eligible

  • Patients who are human immunodeficiency virus (HIV)-positive are eligible if:

    • CD4+ cell count greater or equal to 250 cells/mm^3
    • If patient is on antiretroviral therapy, there must be minimal interactions or overlapping toxicity of the antiretroviral therapy with the experimental cancer treatment; for experimental cancer therapeutics with CYP3A/4 interactions, protease inhibitor therapy is disallowed; suggested regimens to replace protease inhibitor therapy include dolutegravir given with tenofovir/emtricitabine; raltegravir given with tenofovir and emtricitabine; once daily combinations that use pharmacologic boosters may not be used
    • No history of non-malignancy acquired immune deficiency syndrome (AIDS)-defining conditions other than historical low CD4+ cell counts
    • Probable long-term survival with HIV if cancer were not present

  • Any prior therapy, radiotherapy (except palliative radiation therapy of 30 gray [Gy] or less), or major surgery must have been completed >= 4 weeks prior to start of treatment; all adverse events due to prior therapy have resolved to a grade 1 or better (except alopecia and lymphopenia) by start of treatment; palliative radiation therapy must have been completed at least 2 weeks prior to start of treatment; the radiotherapy must not be to a lesion that is included as measurable disease

    • NOTE: Prostate cancer patients may continue their luteinizing hormone-releasing hormone (LHRH) agonist
    • NOTE: For patients entering the study via the original screening process, patients may receive non-protocol treatment after biopsy (if clinically indicated) until they receive notification of results; however, lack of response must be documented prior to registration to Step 1; new non-protocol treatment will NOT be permitted as intervening therapy after registration to Step 0; the only intervening treatment permitted is prior therapy that the patient already received prior to Step 0 registration; the decision to stop the intervening non-protocol treatment will be left up to the treating physician if patient has an aMOI; however, patients will need to be off such therapy for at least 4 weeks before receiving any MATCH protocol treatment
    • NOTE: For patients entering the study via a designated outside laboratory, no intervening systemic non-protocol treatment is permitted after Step 0 registration; all other eligibility requirements still apply to these patients, including the washouts for prior therapy noted above in this section, the time restrictions outlined, and the eligibility criteria for the intended subprotocol

  • Patients with brain metastases or primary brain tumors must have completed treatment, surgery or radiation therapy >= 4 weeks prior to start of treatment

  • Patients must have discontinued steroids >= 1 week prior to registration to Step 0 and remain off steroids thereafter, except as permitted; patients with glioblastoma (GBM) must have been on stable dose of steroids, or be off steroids, for one week prior to registration to treatment (Step 1, 3, 5, 7)

    • NOTE: The following steroids are permitted (low dose steroid use is defined as prednisone 10 mg daily or less, or bioequivalent dose of other corticosteroid):

      • Temporary steroid use: e.g. for CT imaging in setting of contrast allergy

      • Low dose steroid use for appetite

      • Chronic inhaled steroid use

      • Steroid injections for joint disease

      • Stable dose of replacement steroid for adrenal insufficiency or low doses for non-malignant disease

      • Topical steroid

      • Steroids required to manage toxicity related to study treatment, as described in the subprotocols

      • Steroids required as pre- or post-chemotherapy medication for acceptable intervening chemotherapy

        • NOTE: Steroids must be completed alongside last dose of chemotherapy

  • Leukocytes >= 3,000/mcL (within 2 weeks prior to screening step registration and within 4 weeks prior to treatment step registration)

  • Absolute neutrophil count (ANC) >= 1,500/mcL (within 2 weeks prior to screening step registration and within 4 weeks prior to treatment step registration)

  • Platelets >= 100,000/mcL (within 2 weeks prior to screening step registration and within 4 weeks prior to treatment step registration)

  • NOTE: Patients with documented bone marrow involvement by lymphoma are not required to meet the above hematologic parameters, but must have a platelet count of at least 75,000/mcL and neutrophil count of at least 1,000/mcL

  • Total bilirubin =< 1.5 x institutional upper limit of normal (ULN) (unless documented Gilbert's syndrome, for which bilirubin =< 3 x institutional ULN is permitted) (within 2 weeks prior to screening step registration and within 4 weeks prior to treatment step registration)

  • Aspartate aminotransferase (AST) (serum glutamic oxaloacetic transaminase [SGOT])/alanine aminotransferase (ALT) (serum glutamate pyruvate transaminase [SGPT]) =< 2.5 x institutional ULN (up to 5 times ULN in presence of liver metastases) (within 2 weeks prior to screening step registration and within 4 weeks prior to treatment step registration)

  • Creatinine clearance >= 45 mL/min/1.73 m^2 for patients with creatinine levels above institutional ULN

    • As defined by the Cockcroft-Gault equation (within 2 weeks prior to screening step registration and within 4 weeks prior to treatment step registration)

  • Patients must have an electrocardiogram (ECG) within 8 weeks prior to registration to screening step and must meet the following cardiac criteria:

    • Resting corrected QT interval (QTc) =< 480 msec

      • NOTE: If the first recorded QTc exceeds 480 msec, two additional, consecutive ECGs are required and must result in a mean resting QTc =< 480 msec; it is recommended that there are 10-minute (+/- 5 minutes) breaks between the ECGs

    • The following only need to be assessed if the mean QTc > 480 msec

      • Check potassium and magnesium serum levels
      • Correct any identified hypokalemia and/or hypomagnesemia and may repeat ECG to confirm exclusion of patient due to QTc
      • For patients with heart rate (HR) 60-100 beats per minute (bpm), no manual read of QTc is required
      • For patients with baseline HR < 60 or > 100 bpm, manual read of QT by trained personnel is required, with Fridericia correction applied to determine QTc
      • Patient must not have hypokalemia (value < institutional lower limit of normal)

    • No factors that increase the risk of QTc prolongation or risk of arrhythmic events such as heart failure, congenital long QT syndrome, family history of long QT syndrome or unexplained sudden death under 40 years of age or any concomitant medication known to prolong the QT interval

      • NOTE: Patient must be taken off prohibited medication prior to registration to the screening step (Step 0, 2, 4, 6) and remain off these medications thereafter, unless permitted on a subprotocol for the management of treatment related toxicity; patient must be off the drug for at least 5 half-lives prior to registration to the treatment step (Step 1, 3, 5, 7); the medication half-life can be found in the package insert for Food and Drug Administration (FDA) approved drugs

  • ELIGIBILITY CRITERIA FOR FIRST TREATMENT (STEP 1)

  • NOTE: For patients entering step 0 with assay results from outside laboratories, no systemic treatment is allowed after step 0 registration

  • As MATCH is designed to add additional subprotocols, implement limited expansions of accrual for certain subprotocols, and/or amend existing arm-specific eligibility criteria, some patients entering under the original screening method may be eligible to have their results rerun in MATCHbox, even if they did not match to a treatment initially or did not receive a treatment assignment due to a lack of available assignment slots; patients whose sequence results will be rerun through MATCHbox must also meet the following criteria:

    • Samples must have been collected within 5 months of the activation of the addendum, as there is an additional month needed to get the patients on trial

    • Patient has not had treatment within the 5 months that resulted in a PR or better after the performance of the screening assessment

    • Patient must meet eligibility criteria, including performance status 1 or better and life expectancy of at least 3 months

    • Patients must meet the eligibility requirements with the following exceptions:

      • Patients may have received other non-targeted, immunotherapy or targeted treatment, which could be stopped in favor of returning to MATCH, if no response to the interim treatment has occurred and no further benefit is expected from this interim treatment, per the treating physician's discretion; documentation of a lack of response to the interim treatment is not required in these cases; however, the following restrictions apply:

        • Enrollment onto another investigational therapeutic study is not permitted
        • Patient cannot be responding to interim treatment, since the benefit of the MATCH treatment is unknown and may deprive patient of an effective treatment if it were given when a patient is responding to another treatment

    • NOTE: Patients meeting these criteria will NOT be biopsied at this time point; instead, their step 0 results will be re-interrogated to determine if another treatment is available

  • ELIGIBILITY CRITERIA FOR SECOND SCREENING (STEP 2)

  • Patient's disease has progressed on Step 1 treatment or patient could not tolerate assigned treatment

    • NOTE: PATIENTS ENTERING STEP 1 WITH A "RARE VARIANT" FROM AN "OUTSIDE" LAB ARE NOT ELIGIBLE FOR STEP 2

  • No response and progression (or inability to tolerate further treatment) occurred < 6 months from start of step 1 treatment

    • NOTE: Patients meeting these criteria will NOT be biopsied at this time point; instead, their step 0 MATCH assay results will be re-interrogated to determine if another treatment is available upon registration to this study step; it is not necessary to confirm the availability of another potential treatment assignment in advance; only aMOIs detected by the MATCH assay may be used for the determination of eligibility to a relevant subprotocol OR

  • Progression (or inability to tolerate further treatment) occurred after a (1) response OR (2) after >= 6 months from start of step 1 treatment; patient must have tumor amenable to percutaneous biopsy and be willing and able to undergo a tumor biopsy or bone marrow aspirate for collection and submission of tumor tissue OR patient will be undergoing a procedure due to medical necessity during which the tissue may be collected for the central determination of the presence of one or more of the specific "actionable" mutations/amplifications of interest (aMOI); archived specimens cannot be accepted

  • Patients must meet eligibility criteria as defined in step 0

  • Patient must not have been assigned to step 1 treatment based on a "rare variant" determined by a designated outside laboratory

  • ELIGIBILITY CRITERIA FOR SECOND TREATMENT (STEP 3)

  • NOTE: If screening biopsy samples were submitted during step 2, patients may receive non-protocol treatment after biopsy (if clinically indicated) until they receive notification of results however, lack of response must be documented prior to registration to step 3; new non-protocol treatment will NOT be permitted as intervening therapy after registration to step 2; the decision to stop the intervening nonprotocol treatment will be left up to the treating physician if patient has an aMOI; waiting periods as described will apply

  • ELIGIBILITY CRITERIA FOR THIRD SCREENING (STEP 4)

  • Patient's disease has progressed on step 3 treatment or patient could not tolerate assigned treatment

    • Patient must meet one of the following criteria:

      • No response and progression (or inability to tolerate further treatment) occurred < 6 months from start of step 3 (second) treatment AND a biopsy was performed at step 2 screening

        • NOTE: Patients meeting these criteria will NOT be biopsied at this time point; instead, their latest MATCH assay results will be re-interrogated to determine if another treatment is available upon registration to this study step; it is not necessary to confirm the availability of another potential treatment assignment in advance OR

      • Progression (or inability to tolerate further treatment) occurred on step 3 treatment and a biopsy was not performed at step 2 screening (due to presence of a

Studie plan

Dit gedeelte bevat details van het studieplan, inclusief hoe de studie is opgezet en wat de studie meet.

Hoe is de studie opgezet?

Ontwerpdetails

  • Primair doel: Screening
  • Toewijzing: Niet-gerandomiseerd
  • Interventioneel model: Parallelle opdracht
  • Masker: Geen (open label)

Wapens en interventies

Deelnemersgroep / Arm

Deelnemersgroep / Arm

Een groep of subgroep van deelnemers aan een klinische studie die een specifieke interventie/behandeling krijgt, of geen interventie, volgens het protocol van de studie.
Interventie / Behandeling

Interventie / Behandeling

Een proces of actie die centraal staat in een klinische studie. Interventies omvatten medicijnen, medische hulpmiddelen, procedures, vaccins en andere producten die in onderzoek zijn of al beschikbaar zijn. Interventies kunnen ook niet-invasieve benaderingen omvatten, zoals onderwijs of het aanpassen van voeding en lichaamsbeweging.
Experimenteel: Subprotocol A (EGFR activating mutation)

Patients with EGFR activating mutation receive afatinib orally (PO) once daily (QD) on days 1-28 of each cycle. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity. Additionally, patients undergo CT or MRI during screening and on study, as well as during follow-up as clinically necessary. Patients may also undergo ECHO or nuclear study throughout the trial as clinically necessary. Patients undergo biopsies and blood sample collection on study.
Procedure: Biospecimen Collection

Undergo collection of blood samples

Andere namen:
  • Biologische monsterverzameling
  • Biospecimen verzameld
  • Specimenverzameling
  • Monsterverzameling
Geneesmiddel: Afatinib

Given PO

Andere namen:
  • BIBW 2992
  • BIBW2992
  • BIBW-2992
Geneesmiddel: Afatinib Dimaleate

Given PO

Andere namen:
  • (2E)-N-(4-((3-chloor-4-fluorfenyl)amino)-7-(((3S)-tetrahydrofuran-3-yl)oxy)chinazoline-6-yl)-4-(dimethylamino) but-2-eenamide bis(waterstof (2Z)-but-2-eendioaat)
  • BIBW 2992MA2
  • BIBW2992 MA2
  • Gilotrif
Procedure: Biopsy Procedure

Undergo tumor biopsy

Andere namen:
  • Bx
  • BIOSY_TYPE
  • Biopsie
Procedure: Computed Tomography

Undergo computed tomography (CT)

Andere namen:
  • CT
  • KAT
  • CT-scan
  • Axiale computertomografie
  • Computergestuurde axiale tomografie
  • Computergestuurde tomografie
  • tomografie
  • Geautomatiseerde axiale tomografie (procedure)
  • Computertomografie (CT)-scan
  • Diagnostische kattencan
  • Diagnostisch CAT -scanservice type
Ander: Cytology Specimen Collection Procedure

Optional correlative studies

Andere namen:
  • Cytologische bemonstering
Procedure: Echocardiography Test

Undergo echocardiography (ECHO)

Andere namen:
  • Echocardiografie
  • EG
Ander: Laboratory Biomarker Analysis

Undergo molecular analysis

Procedure: Magnetic Resonance Imaging

Undergo magnetic resonance imaging (MRI)

Andere namen:
  • MRI
  • Magnetische resonantie
  • Magnetic Resonance Imaging-scan
  • Medische beeldvorming, magnetische resonantie / nucleaire magnetische resonantie
  • DHR
  • MR-beeldvorming
  • MRI scan
  • NMR-beeldvorming
  • NMRI
  • Nucleaire magnetische resonantie beeldvorming
  • Magnetische resonantiebeeldvorming (MRI)
  • sMRI
  • Magnetische resonantiebeeldvorming (procedure)
  • MRI's
  • Structurele MRI
Procedure: Radionuclide Imaging

Undergo nuclear study

Andere namen:
  • NM
  • Nucleair medicijn
  • scan van de nucleaire geneeskunde
  • radiografie
  • Scannen van radionucliden
  • Scannen
  • Scintigrafie
  • Gamma Scan
Experimenteel: Subprotocol B (HER2 activating mutation)

Patients with HER2 activating mutation receive afatinib PO QD on days 1-28. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity.
Geneesmiddel: Afatinib

Given PO

Andere namen:
  • BIBW 2992
  • BIBW2992
  • BIBW-2992
Geneesmiddel: Afatinib Dimaleate

Given PO

Andere namen:
  • (2E)-N-(4-((3-chloor-4-fluorfenyl)amino)-7-(((3S)-tetrahydrofuran-3-yl)oxy)chinazoline-6-yl)-4-(dimethylamino) but-2-eenamide bis(waterstof (2Z)-but-2-eendioaat)
  • BIBW 2992MA2
  • BIBW2992 MA2
  • Gilotrif
Ander: Cytology Specimen Collection Procedure

Optional correlative studies

Andere namen:
  • Cytologische bemonstering
Ander: Laboratory Biomarker Analysis

Undergo molecular analysis
Experimenteel: Subprotocol C1 (MET amplification)

Patients with MET amplification receive crizotinib PO BID on days 1-28. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity. Patients also undergo radiologic evaluation and collection of blood samples throughout the study. Patients may undergo biopsy at screening, on study, and/or at end of treatment.
Geneesmiddel: Crizotinib

Given PO

Andere namen:
  • MET-tyrosinekinaseremmer PF-02341066
  • PF-02341066
  • PF-2341066
  • Xalkori
  • PF02341066
  • PF 02341066
  • Alkixen
  • Crizocent
Procedure: Biospecimen Collection

Undergo collection of blood samples

Andere namen:
  • Biologische monsterverzameling
  • Biospecimen verzameld
  • Specimenverzameling
  • Monsterverzameling
Procedure: Biopsy Procedure

Undergo tumor biopsy

Andere namen:
  • Bx
  • BIOSY_TYPE
  • Biopsie
Ander: Cytology Specimen Collection Procedure

Optional correlative studies

Andere namen:
  • Cytologische bemonstering
Ander: Laboratory Biomarker Analysis

Undergo molecular analysis

Procedure: Radiologic Examination

Undergo radiologic evaluation

Andere namen:
  • Radiologische evaluatie
  • Radiologisch onderzoek
Experimenteel: Subprotocol C2 (MET exon 14 deletion/mutation)

Patients with MET exon 14 deletion or other mutations that disrupt exon 14 receive crizotinib PO BID on days 1-28. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity. Patients undergo tumor biopsy on study and undergo radiologic evaluation and blood sample collection throughout the study.
Geneesmiddel: Crizotinib

Given PO

Andere namen:
  • MET-tyrosinekinaseremmer PF-02341066
  • PF-02341066
  • PF-2341066
  • Xalkori
  • PF02341066
  • PF 02341066
  • Alkixen
  • Crizocent
Procedure: Biospecimen Collection

Undergo collection of blood samples

Andere namen:
  • Biologische monsterverzameling
  • Biospecimen verzameld
  • Specimenverzameling
  • Monsterverzameling
Procedure: Biopsy Procedure

Undergo tumor biopsy

Andere namen:
  • Bx
  • BIOSY_TYPE
  • Biopsie
Ander: Cytology Specimen Collection Procedure

Optional correlative studies

Andere namen:
  • Cytologische bemonstering
Ander: Laboratory Biomarker Analysis

Undergo molecular analysis

Procedure: Radiologic Examination

Undergo radiologic evaluation

Andere namen:
  • Radiologische evaluatie
  • Radiologisch onderzoek
Experimenteel: Subprotocol E (EGFR T790M or rare activating mutation)

Patients with EGFR T790M or rare activating mutation receive osimertinib (AZD9291) PO QD on days 1-28 of each cycle. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity. Patients also undergo radiologic evaluation throughout the trial, ECHO or multigated acquisition scan (MUGA) during screening, and biopsy and collection of blood samples on trial and at end of treatment.
Procedure: Multigated Acquisition Scan

Undergo MUGA

Andere namen:
  • Blood Pool-scan
  • Equilibrium radionuclide angiografie
  • Gated Blood Pool-beeldvorming
  • MUGA
  • Radionuclide ventriculografie
  • RNVG
  • SYMA scannen
  • Gesynchroniseerde Multigated Acquisitie Scannen
  • MUGA-scan
  • Multi-Gated Acquisitie Scan
  • Radionuclide ventriculogram scan
  • Gated Heart Pool-scan
  • RNV-scan
Procedure: Biospecimen Collection

Undergo collection of blood samples

Andere namen:
  • Biologische monsterverzameling
  • Biospecimen verzameld
  • Specimenverzameling
  • Monsterverzameling
Procedure: Biopsy Procedure

Undergo tumor biopsy

Andere namen:
  • Bx
  • BIOSY_TYPE
  • Biopsie
Ander: Cytology Specimen Collection Procedure

Optional correlative studies

Andere namen:
  • Cytologische bemonstering
Procedure: Echocardiography Test

Undergo echocardiography (ECHO)

Andere namen:
  • Echocardiografie
  • EG
Ander: Laboratory Biomarker Analysis

Undergo molecular analysis

Procedure: Radiologic Examination

Undergo radiologic evaluation

Andere namen:
  • Radiologische evaluatie
  • Radiologisch onderzoek
Geneesmiddel: Osimertinib

Given PO

Andere namen:
  • AZD-9291
  • AZD9291
  • Mereletinib
  • AZD 9291
Experimenteel: Subprotocol F (ALK translocation)

Patients with ALK translocation receive crizotinib PO twice daily (BID) on days 1-28. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity.
Geneesmiddel: Crizotinib

Given PO

Andere namen:
  • MET-tyrosinekinaseremmer PF-02341066
  • PF-02341066
  • PF-2341066
  • Xalkori
  • PF02341066
  • PF 02341066
  • Alkixen
  • Crizocent
Ander: Cytology Specimen Collection Procedure

Optional correlative studies

Andere namen:
  • Cytologische bemonstering
Ander: Laboratory Biomarker Analysis

Undergo molecular analysis
Experimenteel: Subprotocol G (ROS1 translocation or inversion)

Patients with ROS1 translocation or inversion receive crizotinib PO BID on days 1-28. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity.
Geneesmiddel: Crizotinib

Given PO

Andere namen:
  • MET-tyrosinekinaseremmer PF-02341066
  • PF-02341066
  • PF-2341066
  • Xalkori
  • PF02341066
  • PF 02341066
  • Alkixen
  • Crizocent
Ander: Cytology Specimen Collection Procedure

Optional correlative studies

Andere namen:
  • Cytologische bemonstering
Ander: Laboratory Biomarker Analysis

Undergo molecular analysis
Experimenteel: Subprotocol H (BRAF V600E/R/K/D mutation)

Patients with BRAF V600E/R/K/D mutation receive dabrafenib PO BID and trametinib PO QD on days 1-28. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity.
Geneesmiddel: Trametinib

Given PO

Andere namen:
  • GSK1120212
  • JTP-74057
  • MEK-remmer GSK1120212
  • GSK-1120212
  • GSK 212
  • GSK-212
  • GSK212
  • JTP74057
Geneesmiddel: Dabrafenib Mesylate

Given PO

Andere namen:
  • Dabrafenib methaansulfonaat
  • GSK2118436 Methaansulfonaatzout
  • GSK2118436B
  • Tafinlar
Ander: Cytology Specimen Collection Procedure

Optional correlative studies

Andere namen:
  • Cytologische bemonstering
Ander: Laboratory Biomarker Analysis

Undergo molecular analysis

Geneesmiddel: Dabrafenib

Given PO

Andere namen:
  • GSK2118436
  • BRAF-remmer GSK2118436
  • GSK-2118436
  • GSK-2118436A
  • GSK2118436A
Experimenteel: Subprotocol I (PIK3CA mutation)

Patients with PIK3CA mutation without RAS mutation or PTEN loss receive taselisib PO QD on days 1-28. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity.
Ander: Cytology Specimen Collection Procedure

Optional correlative studies

Andere namen:
  • Cytologische bemonstering
Ander: Laboratory Biomarker Analysis

Undergo molecular analysis

Geneesmiddel: Taselisib

Given PO

Andere namen:
  • GDC-0032
  • RO5537381
Experimenteel: Subprotocol J (HER2 amplification >= 7 copy numbers)

Patients receive pertuzumab IV over 30-60 minutes and trastuzumab IV over 30 minutes on day 1 of each cycle. Cycles repeat every 3 weeks in the absence of disease progression or unacceptable toxicity. Patients also undergo radiologic evaluation throughout the trial, ECHO at screening and end of treatment, and biopsy and collection of blood samples on trial and at end of treatment.
Biologisch: Trastuzumab

Given IV

Andere namen:
  • Herceptin
  • ABP 980
  • ALT02
  • Herceptin Biosimilar PF-05280014
  • Herceptin Trastuzumab Biosimilar PF-05280014
  • Herzuma
  • Ogivr
  • Ontruzant
  • PF-05280014
  • rhuMAb HER2
  • RO0452317
  • SB3
  • Trastuzumab Biosimilar ABP 980
  • Trastuzumab Biosimilar ALT02
  • trastuzumab biosimilar EG12014
  • Trastuzumab Biosimilar HLX02
  • Trastuzumab Biosimilar PF-05280014
  • Trastuzumab Biosimilar SB3
  • Trastuzumab-dkst
  • Trastuzumab-dttb
  • Trastuzumab-pkrb
  • Trazimera
  • Kanjinti
  • Trastuzumab Biosimilar SIBP-01
  • Trastuzumab-anns
  • Trastuzumab-qyyp
  • Herclon
  • Zercepac
  • QL 1701
  • QL-1701
  • QL1701
  • Trastuzumab Biosimilar QL1701
  • CT-P06
  • CT-P6
  • Trastuzumab Biosimilar CT-P6
  • Biceltis
  • CANMab
  • Hertraz
  • Hercessi
  • Trastuzumab-strf
  • Herwenda
  • Trastuzumab-herw
  • Trastuzumab-zerc
  • HLX 02
  • HLX-02
  • HLX02
  • PF 05280014
  • PF05280014
  • Trastuzumab-tuzn
  • Tuznue
Biologisch: Pertuzumab

Given IV

Andere namen:
  • Perjeta
  • 2C4
  • 2C4 antilichaam
  • EG1206A
  • HLX11
  • HS627
  • MoAb 2C4
  • Monoklonaal antilichaam 2C4
  • Omnitarg
  • Pertuzumab Biosimilar EG1206A
  • Pertuzumab Biosimilar HLX11
  • Pertuzumab Biosimilar HS627
  • rhuMAb2C4
  • RO4368451
  • BCD-178
  • Pertuzumab Biosimilar BCD-178
  • Rhumab 2C4
  • Pertuzumab Biosimilar TQB2440
  • TQB 2440
  • TQB-2440
  • TQB2440
  • Pertuzumab-dpzb
  • Poherdy
Procedure: Biospecimen Collection

Undergo collection of blood samples

Andere namen:
  • Biologische monsterverzameling
  • Biospecimen verzameld
  • Specimenverzameling
  • Monsterverzameling
Procedure: Biopsy Procedure

Undergo tumor biopsy

Andere namen:
  • Bx
  • BIOSY_TYPE
  • Biopsie
Procedure: Echocardiography Test

Undergo echocardiography (ECHO)

Andere namen:
  • Echocardiografie
  • EG
Ander: Laboratory Biomarker Analysis

Undergo molecular analysis

Procedure: Radiologic Examination

Undergo radiologic evaluation

Andere namen:
  • Radiologische evaluatie
  • Radiologisch onderzoek
Experimenteel: Subprotocol K1 (FGFR amplification)

Patients with FGFR amplification receive erdafitinib PO QD on days 1-28. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity. Patients also undergo CT and MRI throughout study. Patients may also undergo blood sample collection and tumor biopsy throughout the trial.
Procedure: Biospecimen Collection

Undergo collection of blood samples

Andere namen:
  • Biologische monsterverzameling
  • Biospecimen verzameld
  • Specimenverzameling
  • Monsterverzameling
Procedure: Biopsy Procedure

Undergo tumor biopsy

Andere namen:
  • Bx
  • BIOSY_TYPE
  • Biopsie
Procedure: Computed Tomography

Undergo computed tomography (CT)

Andere namen:
  • CT
  • KAT
  • CT-scan
  • Axiale computertomografie
  • Computergestuurde axiale tomografie
  • Computergestuurde tomografie
  • tomografie
  • Geautomatiseerde axiale tomografie (procedure)
  • Computertomografie (CT)-scan
  • Diagnostische kattencan
  • Diagnostisch CAT -scanservice type
Ander: Cytology Specimen Collection Procedure

Optional correlative studies

Andere namen:
  • Cytologische bemonstering
Ander: Laboratory Biomarker Analysis

Undergo molecular analysis

Procedure: Magnetic Resonance Imaging

Undergo magnetic resonance imaging (MRI)

Andere namen:
  • MRI
  • Magnetische resonantie
  • Magnetic Resonance Imaging-scan
  • Medische beeldvorming, magnetische resonantie / nucleaire magnetische resonantie
  • DHR
  • MR-beeldvorming
  • MRI scan
  • NMR-beeldvorming
  • NMRI
  • Nucleaire magnetische resonantie beeldvorming
  • Magnetische resonantiebeeldvorming (MRI)
  • sMRI
  • Magnetische resonantiebeeldvorming (procedure)
  • MRI's
  • Structurele MRI
Geneesmiddel: Erdafitinib

Given PO

Andere namen:
  • Balversa
  • JNJ-42756493
  • JNJ42756493
Experimenteel: Subprotocol K2 (FGFR mutation or fusion)

Patients with FGFR mutation or fusion receive erdafitinib PO QD on days 1-28. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity. Additionally, patients undergo blood sample collection, CT or MRI, and tumor biopsy throughout the study.
Procedure: Biospecimen Collection

Undergo collection of blood samples

Andere namen:
  • Biologische monsterverzameling
  • Biospecimen verzameld
  • Specimenverzameling
  • Monsterverzameling
Procedure: Biopsy Procedure

Undergo tumor biopsy

Andere namen:
  • Bx
  • BIOSY_TYPE
  • Biopsie
Procedure: Computed Tomography

Undergo computed tomography (CT)

Andere namen:
  • CT
  • KAT
  • CT-scan
  • Axiale computertomografie
  • Computergestuurde axiale tomografie
  • Computergestuurde tomografie
  • tomografie
  • Geautomatiseerde axiale tomografie (procedure)
  • Computertomografie (CT)-scan
  • Diagnostische kattencan
  • Diagnostisch CAT -scanservice type
Ander: Cytology Specimen Collection Procedure

Optional correlative studies

Andere namen:
  • Cytologische bemonstering
Ander: Laboratory Biomarker Analysis

Undergo molecular analysis

Procedure: Magnetic Resonance Imaging

Undergo magnetic resonance imaging (MRI)

Andere namen:
  • MRI
  • Magnetische resonantie
  • Magnetic Resonance Imaging-scan
  • Medische beeldvorming, magnetische resonantie / nucleaire magnetische resonantie
  • DHR
  • MR-beeldvorming
  • MRI scan
  • NMR-beeldvorming
  • NMRI
  • Nucleaire magnetische resonantie beeldvorming
  • Magnetische resonantiebeeldvorming (MRI)
  • sMRI
  • Magnetische resonantiebeeldvorming (procedure)
  • MRI's
  • Structurele MRI
Geneesmiddel: Erdafitinib

Given PO

Andere namen:
  • Balversa
  • JNJ-42756493
  • JNJ42756493
Experimenteel: Subprotocol L (mTOR mutation)

Patients with mTOR mutation receive sapanisertib PO daily on days 1-28. Cycles repeat every 3 weeks in the absence of disease progression or unacceptable toxicity.
Ander: Cytology Specimen Collection Procedure

Optional correlative studies

Andere namen:
  • Cytologische bemonstering
Ander: Laboratory Biomarker Analysis

Undergo molecular analysis

Geneesmiddel: Sapanisertib

Given PO

Andere namen:
  • INKT-128
  • INK128
  • MLN-0128
  • MLN0128
  • TAK-228
Experimenteel: Subprotocol M (TSC1 or TSC2 mutation)

Patients with TSC1 or TSC2 mutation receive sapanisertib PO daily on days 1-28. Cycles repeat every 3 weeks in the absence of disease progression or unacceptable toxicity.
Ander: Cytology Specimen Collection Procedure

Optional correlative studies

Andere namen:
  • Cytologische bemonstering
Ander: Laboratory Biomarker Analysis

Undergo molecular analysis

Geneesmiddel: Sapanisertib

Given PO

Andere namen:
  • INKT-128
  • INK128
  • MLN-0128
  • MLN0128
  • TAK-228
Experimenteel: Subprotocol N (PTEN mutation or deletion and PTEN expression)

Patients with PTEN mutation or deletion and PTEN expression receive PI3K-beta inhibitor GSK2636771 PO QD on days 1-28. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity.
Ander: Cytology Specimen Collection Procedure

Optional correlative studies

Andere namen:
  • Cytologische bemonstering
Ander: Laboratory Biomarker Analysis

Undergo molecular analysis

Geneesmiddel: PI3K-beta Inhibitor GSK2636771

Given PO

Andere namen:
  • GSK-2636771
  • GSK2636771
Experimenteel: Subprotocol P (PTEN loss)

Patients with PTEN loss receive PI3K-beta inhibitor GSK2636771 PO QD on days 1-28. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity.
Ander: Cytology Specimen Collection Procedure

Optional correlative studies

Andere namen:
  • Cytologische bemonstering
Ander: Laboratory Biomarker Analysis

Undergo molecular analysis

Geneesmiddel: PI3K-beta Inhibitor GSK2636771

Given PO

Andere namen:
  • GSK-2636771
  • GSK2636771
Experimenteel: Subprotocol Q (HER2 amplification)

Patients with HER2 amplification receive trastuzumab emtansine intravenously (IV) over 30-90 minutes on day 1. Cycles repeat every 21 days in the absence of disease progression or unacceptable toxicity.
Biologisch: Trastuzumab

Given IV

Andere namen:
  • Herceptin
  • ABP 980
  • ALT02
  • Herceptin Biosimilar PF-05280014
  • Herceptin Trastuzumab Biosimilar PF-05280014
  • Herzuma
  • Ogivr
  • Ontruzant
  • PF-05280014
  • rhuMAb HER2
  • RO0452317
  • SB3
  • Trastuzumab Biosimilar ABP 980
  • Trastuzumab Biosimilar ALT02
  • trastuzumab biosimilar EG12014
  • Trastuzumab Biosimilar HLX02
  • Trastuzumab Biosimilar PF-05280014
  • Trastuzumab Biosimilar SB3
  • Trastuzumab-dkst
  • Trastuzumab-dttb
  • Trastuzumab-pkrb
  • Trazimera
  • Kanjinti
  • Trastuzumab Biosimilar SIBP-01
  • Trastuzumab-anns
  • Trastuzumab-qyyp
  • Herclon
  • Zercepac
  • QL 1701
  • QL-1701
  • QL1701
  • Trastuzumab Biosimilar QL1701
  • CT-P06
  • CT-P6
  • Trastuzumab Biosimilar CT-P6
  • Biceltis
  • CANMab
  • Hertraz
  • Hercessi
  • Trastuzumab-strf
  • Herwenda
  • Trastuzumab-herw
  • Trastuzumab-zerc
  • HLX 02
  • HLX-02
  • HLX02
  • PF 05280014
  • PF05280014
  • Trastuzumab-tuzn
  • Tuznue
Ander: Cytology Specimen Collection Procedure

Optional correlative studies

Andere namen:
  • Cytologische bemonstering
Ander: Laboratory Biomarker Analysis

Undergo molecular analysis

Biologisch: Trastuzumab Emtansine

Given IV

Andere namen:
  • RO5304020
  • Kadcyla
  • Ado Trastuzumab Emtansine
  • ADO-trastuzumab-emtansine
  • PRO132365
  • T-DM1
  • Trastuzumab-DM1
  • Trastuzumab-MCC-DM1
  • Trastuzumab-MCC-DM1 antilichaam-medicijnconjugaat
  • Trastuzumab-MCC-DM1 Immunoconjugaat
  • TDM1
  • PRO-132365
Experimenteel: Subprotocol R (BRAF fusion or BRAF non-V600 mutation)

Patients with BRAF fusion or BRAF non-V600 mutation receive trametinib PO QD on days 1-28. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity.
Geneesmiddel: Trametinib

Given PO

Andere namen:
  • GSK1120212
  • JTP-74057
  • MEK-remmer GSK1120212
  • GSK-1120212
  • GSK 212
  • GSK-212
  • GSK212
  • JTP74057
Ander: Cytology Specimen Collection Procedure

Optional correlative studies

Andere namen:
  • Cytologische bemonstering
Ander: Laboratory Biomarker Analysis

Undergo molecular analysis
Experimenteel: Subprotocol S1 (NF1 mutation)

Patients with NF1 mutation receive trametinib PO QD on days 1-28. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity.
Geneesmiddel: Trametinib

Given PO

Andere namen:
  • GSK1120212
  • JTP-74057
  • MEK-remmer GSK1120212
  • GSK-1120212
  • GSK 212
  • GSK-212
  • GSK212
  • JTP74057
Ander: Cytology Specimen Collection Procedure

Optional correlative studies

Andere namen:
  • Cytologische bemonstering
Ander: Laboratory Biomarker Analysis

Undergo molecular analysis
Experimenteel: Subprotocol S2 (GNAQ or GNA11 mutation)

Patients with GNAQ or GNA11 mutation receive trametinib PO QD on days 1-28. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity.
Geneesmiddel: Trametinib

Given PO

Andere namen:
  • GSK1120212
  • JTP-74057
  • MEK-remmer GSK1120212
  • GSK-1120212
  • GSK 212
  • GSK-212
  • GSK212
  • JTP74057
Ander: Cytology Specimen Collection Procedure

Optional correlative studies

Andere namen:
  • Cytologische bemonstering
Ander: Laboratory Biomarker Analysis

Undergo molecular analysis
Experimenteel: Subprotocol T (SMO or PTCH1 mutation)

Patients with SMO or PTCH1 mutation receive vismodegib PO QD on days 1-28. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity. Patients undergo ECHO or nuclear study during screening, tumor biopsy on study and CT scan, MRI and blood sample collection throughout the study.
Procedure: Biospecimen Collection

Undergo collection of blood samples

Andere namen:
  • Biologische monsterverzameling
  • Biospecimen verzameld
  • Specimenverzameling
  • Monsterverzameling
Procedure: Biopsy Procedure

Undergo tumor biopsy

Andere namen:
  • Bx
  • BIOSY_TYPE
  • Biopsie
Procedure: Computed Tomography

Undergo computed tomography (CT)

Andere namen:
  • CT
  • KAT
  • CT-scan
  • Axiale computertomografie
  • Computergestuurde axiale tomografie
  • Computergestuurde tomografie
  • tomografie
  • Geautomatiseerde axiale tomografie (procedure)
  • Computertomografie (CT)-scan
  • Diagnostische kattencan
  • Diagnostisch CAT -scanservice type
Ander: Cytology Specimen Collection Procedure

Optional correlative studies

Andere namen:
  • Cytologische bemonstering
Procedure: Echocardiography Test

Undergo echocardiography (ECHO)

Andere namen:
  • Echocardiografie
  • EG
Ander: Laboratory Biomarker Analysis

Undergo molecular analysis

Procedure: Magnetic Resonance Imaging

Undergo magnetic resonance imaging (MRI)

Andere namen:
  • MRI
  • Magnetische resonantie
  • Magnetic Resonance Imaging-scan
  • Medische beeldvorming, magnetische resonantie / nucleaire magnetische resonantie
  • DHR
  • MR-beeldvorming
  • MRI scan
  • NMR-beeldvorming
  • NMRI
  • Nucleaire magnetische resonantie beeldvorming
  • Magnetische resonantiebeeldvorming (MRI)
  • sMRI
  • Magnetische resonantiebeeldvorming (procedure)
  • MRI's
  • Structurele MRI
Procedure: Radionuclide Imaging

Undergo nuclear study

Andere namen:
  • NM
  • Nucleair medicijn
  • scan van de nucleaire geneeskunde
  • radiografie
  • Scannen van radionucliden
  • Scannen
  • Scintigrafie
  • Gamma Scan
Geneesmiddel: Vismodegib

Given PO

Andere namen:
  • Erivedge
  • GDC-0449
  • Egel-antagonist GDC-0449
  • GDC0449
  • GDC 0449
Experimenteel: Subprotocol U (NF2 inactivating mutation)

Patients with NF2 inactivating mutation receive defactinib PO BID on days 1-28. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity.
Ander: Cytology Specimen Collection Procedure

Optional correlative studies

Andere namen:
  • Cytologische bemonstering
Ander: Laboratory Biomarker Analysis

Undergo molecular analysis

Geneesmiddel: Defactinib

Given PO

Andere namen:
  • PF-04554878
  • VS-6063
Geneesmiddel: Defactinib Hydrochloride

Given PO
Experimenteel: Subprotocol V (cKIT exon 9, 11, 13, or 14 mutation)

Patients with cKIT exon 9, 11, 13, or 14 mutation receive sunitinib PO QD on days 1-28 of each cycle. Cycles repeat every 42 days in the absence of disease progression or unacceptable toxicity. Additionally, patients undergo CT or MRI during screening and on study, as well as during follow-up as clinically necessary. Patients also undergo ECHO or nuclear study throughout the trial as clinically necessary. Patients undergo biopsies and blood sample collection on study.
Procedure: Biospecimen Collection

Undergo collection of blood samples

Andere namen:
  • Biologische monsterverzameling
  • Biospecimen verzameld
  • Specimenverzameling
  • Monsterverzameling
Procedure: Biopsy Procedure

Undergo tumor biopsy

Andere namen:
  • Bx
  • BIOSY_TYPE
  • Biopsie
Procedure: Computed Tomography

Undergo computed tomography (CT)

Andere namen:
  • CT
  • KAT
  • CT-scan
  • Axiale computertomografie
  • Computergestuurde axiale tomografie
  • Computergestuurde tomografie
  • tomografie
  • Geautomatiseerde axiale tomografie (procedure)
  • Computertomografie (CT)-scan
  • Diagnostische kattencan
  • Diagnostisch CAT -scanservice type
Ander: Cytology Specimen Collection Procedure

Optional correlative studies

Andere namen:
  • Cytologische bemonstering
Procedure: Echocardiography Test

Undergo echocardiography (ECHO)

Andere namen:
  • Echocardiografie
  • EG
Ander: Laboratory Biomarker Analysis

Undergo molecular analysis

Procedure: Magnetic Resonance Imaging

Undergo magnetic resonance imaging (MRI)

Andere namen:
  • MRI
  • Magnetische resonantie
  • Magnetic Resonance Imaging-scan
  • Medische beeldvorming, magnetische resonantie / nucleaire magnetische resonantie
  • DHR
  • MR-beeldvorming
  • MRI scan
  • NMR-beeldvorming
  • NMRI
  • Nucleaire magnetische resonantie beeldvorming
  • Magnetische resonantiebeeldvorming (MRI)
  • sMRI
  • Magnetische resonantiebeeldvorming (procedure)
  • MRI's
  • Structurele MRI
Procedure: Radionuclide Imaging

Undergo nuclear study

Andere namen:
  • NM
  • Nucleair medicijn
  • scan van de nucleaire geneeskunde
  • radiografie
  • Scannen van radionucliden
  • Scannen
  • Scintigrafie
  • Gamma Scan
Geneesmiddel: Sunitinib Malate

Given PO

Andere namen:
  • Sutent
  • SU011248
  • SU11248
  • sunitinib
  • SU 11248
  • SU 011248
  • SU-011248
  • SU-11248
Experimenteel: Subprotocol W (FGFR pathway aberrations)

Patients with FGFR1-3 mutation or translocation receive FGFR Inhibitor AZD4547 PO BID on days 1-28. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity.
Ander: Cytology Specimen Collection Procedure

Optional correlative studies

Andere namen:
  • Cytologische bemonstering
Ander: Laboratory Biomarker Analysis

Undergo molecular analysis

Geneesmiddel: Fexagratinib

Given PO

Andere namen:
  • ABSK-091
  • ABSK091
  • AZD4547
  • KB-74810
  • FGFR-remmer AZD4547
Experimenteel: Subprotocol X (DDR2 S768R, I638F, or L239R mutation)

Patients with DDR2 S768R, I638F, or L239R mutation receive dasatinib PO QD on days 1-28. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity.
Geneesmiddel: Dasatinib

Given PO

Andere namen:
  • BMS-354825
  • Dasatinib hydraat
  • Dasatinib-monohydraat
  • Sprycel
  • GBS 354825
  • BMS354825
Ander: Cytology Specimen Collection Procedure

Optional correlative studies

Andere namen:
  • Cytologische bemonstering
Ander: Laboratory Biomarker Analysis

Undergo molecular analysis
Experimenteel: Subprotocol Y (Akt mutation)

Patients with Akt mutation receive capivasertib PO BID on days 1-4, 8-11, 15-18, and 22-25. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity.
Ander: Cytology Specimen Collection Procedure

Optional correlative studies

Andere namen:
  • Cytologische bemonstering
Ander: Laboratory Biomarker Analysis

Undergo molecular analysis

Geneesmiddel: Capivasertib

Given PO

Andere namen:
  • AZD5363
  • Truqap
  • AZD 5363
  • AZD-5363
Experimenteel: Subprotocol Z1A (NRAS mutation in codon 12, 13, or 61)

Patients with NRAS mutation in codon 12, 13, or 61 receive binimetinib PO BID on days 1-28. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity.
Ander: Cytology Specimen Collection Procedure

Optional correlative studies

Andere namen:
  • Cytologische bemonstering
Ander: Laboratory Biomarker Analysis

Undergo molecular analysis

Geneesmiddel: Binimetinib

Given PO

Andere namen:
  • ARRY-162
  • ARRY-438162
  • MEK162
  • Mektovi
  • ARRY 438162
  • ARRY 162
  • ARRY162
  • ARRY438162
  • MEK 162
  • MEK-162
Experimenteel: Subprotocol Z1B (CCND1, 2, or 3 amplification with Rb by IHC)

Patients with CCND1, 2, or 3 amplification that have tumor Rb expression by IHC receive palbociclib PO QD for 21 days. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity.
Ander: Cytology Specimen Collection Procedure

Optional correlative studies

Andere namen:
  • Cytologische bemonstering
Ander: Laboratory Biomarker Analysis

Undergo molecular analysis

Geneesmiddel: Palbociclib

Given PO

Andere namen:
  • Ibrance
  • 6-Acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazine-1-yl)pyridine-2-yl)amino)-8h-pyrido(2,3-d)pyrimidine-7-on
  • PD 0332991
  • PD 332991
  • PD 991
  • PD-0332991
  • PD0332991
Experimenteel: Subprotocol Z1C (CDK4 or CDK6 amplification and Rb protein)

Patients with CDK4 or CDK6 amplification and tumor Rb protein receive palbociclib PO QD on days 1-21. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity.
Ander: Cytology Specimen Collection Procedure

Optional correlative studies

Andere namen:
  • Cytologische bemonstering
Ander: Laboratory Biomarker Analysis

Undergo molecular analysis

Geneesmiddel: Palbociclib

Given PO

Andere namen:
  • Ibrance
  • 6-Acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazine-1-yl)pyridine-2-yl)amino)-8h-pyrido(2,3-d)pyrimidine-7-on
  • PD 0332991
  • PD 332991
  • PD 991
  • PD-0332991
  • PD0332991
Experimenteel: Subprotocol Z1D (Loss of MLH1 or MSH2 by IHC)

Patients with mismatch repair deficiency (loss of MLH1 or MSH2 by IHC) receive nivolumab IV over 30 minutes on days 1 and 15 for 4 cycles and then on day 1 every 28 days. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity.
Biologisch: Nivolumab

Given IV

Andere namen:
  • BMS-936558
  • MDX-1106
  • NIVO
  • ONO-4538
  • Optie
  • CMAB819
  • Nivolumab Biosimilar CMAB819
  • MDX 1106
  • MDX1106
  • GBS 936558
  • ABP 206
  • Nivolumab Biosimilar ABP 206
  • BCD-263
  • Nivolumab Biosimilar BCD-263
  • BMS936558
  • ONO 4538
  • ONO4538
Ander: Cytology Specimen Collection Procedure

Optional correlative studies

Andere namen:
  • Cytologische bemonstering
Ander: Laboratory Biomarker Analysis

Undergo molecular analysis
Experimenteel: Subprotocol Z1E (NTRK1, NTRK2 or NTRK3 gene fusion)

Patients with NTRK1, NTRK2, or NTRK3 gene fusion receive larotrectinib (LOXO-101) PO BID on days 1-28 of each cycle. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity. Additionally, patients undergo CT or MRI during screening and on study, as well as during follow-up as clinically necessary. Patients also undergo biopsies and blood sample collection on study.
Procedure: Biospecimen Collection

Undergo collection of blood samples

Andere namen:
  • Biologische monsterverzameling
  • Biospecimen verzameld
  • Specimenverzameling
  • Monsterverzameling
Procedure: Biopsy Procedure

Undergo tumor biopsy

Andere namen:
  • Bx
  • BIOSY_TYPE
  • Biopsie
Procedure: Computed Tomography

Undergo computed tomography (CT)

Andere namen:
  • CT
  • KAT
  • CT-scan
  • Axiale computertomografie
  • Computergestuurde axiale tomografie
  • Computergestuurde tomografie
  • tomografie
  • Geautomatiseerde axiale tomografie (procedure)
  • Computertomografie (CT)-scan
  • Diagnostische kattencan
  • Diagnostisch CAT -scanservice type
Ander: Cytology Specimen Collection Procedure

Optional correlative studies

Andere namen:
  • Cytologische bemonstering
Ander: Laboratory Biomarker Analysis

Undergo molecular analysis

Procedure: Magnetic Resonance Imaging

Undergo magnetic resonance imaging (MRI)

Andere namen:
  • MRI
  • Magnetische resonantie
  • Magnetic Resonance Imaging-scan
  • Medische beeldvorming, magnetische resonantie / nucleaire magnetische resonantie
  • DHR
  • MR-beeldvorming
  • MRI scan
  • NMR-beeldvorming
  • NMRI
  • Nucleaire magnetische resonantie beeldvorming
  • Magnetische resonantiebeeldvorming (MRI)
  • sMRI
  • Magnetische resonantiebeeldvorming (procedure)
  • MRI's
  • Structurele MRI
Geneesmiddel: Larotrectinib

Given PO

Andere namen:
  • ARRY 470
  • LOXO 101
  • LOXO-101
  • LOXO101
Geneesmiddel: Larotrectinib Sulfate

Given PO

Andere namen:
  • ARRY 470 Sulfaat
  • LOXO 101 Sulfaat
  • LOXO-101 Sulfaat
  • Vitrakvi
Experimenteel: Subprotocol Z1F (PIK3CA mutation)

Patients receive copanlisib IV over 1 hour on days 1, 8, and 15 of each cycle. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity. Patients also undergo tumor biopsies at screening and end of treatment as well as CT or MRI at baseline and repeated every 2 cycles for the first 26 cycles then every 3 cycles thereafter until progressive disease or start of another MATCH treatment step.
Procedure: Biopsy Procedure

Undergo tumor biopsy

Andere namen:
  • Bx
  • BIOSY_TYPE
  • Biopsie
Procedure: Computed Tomography

Undergo computed tomography (CT)

Andere namen:
  • CT
  • KAT
  • CT-scan
  • Axiale computertomografie
  • Computergestuurde axiale tomografie
  • Computergestuurde tomografie
  • tomografie
  • Geautomatiseerde axiale tomografie (procedure)
  • Computertomografie (CT)-scan
  • Diagnostische kattencan
  • Diagnostisch CAT -scanservice type
Ander: Cytology Specimen Collection Procedure

Optional correlative studies

Andere namen:
  • Cytologische bemonstering
Procedure: Magnetic Resonance Imaging

Undergo magnetic resonance imaging (MRI)

Andere namen:
  • MRI
  • Magnetische resonantie
  • Magnetic Resonance Imaging-scan
  • Medische beeldvorming, magnetische resonantie / nucleaire magnetische resonantie
  • DHR
  • MR-beeldvorming
  • MRI scan
  • NMR-beeldvorming
  • NMRI
  • Nucleaire magnetische resonantie beeldvorming
  • Magnetische resonantiebeeldvorming (MRI)
  • sMRI
  • Magnetische resonantiebeeldvorming (procedure)
  • MRI's
  • Structurele MRI
Geneesmiddel: Copanlisib

Given IV

Andere namen:
  • BAAI 80-6946
  • PI3K-remmer BAY 80-6946
  • Baai 80 6946
  • BAAI 806946
  • BAY-80-6946
  • BAY806946
Geneesmiddel: Copanlisib Hydrochloride

Given IV

Andere namen:
  • 5-Pyrimidinecarboxamide, 2-Amino-N-(2,3-dihydro-7-methoxy-8-(3-(4-morfolinyl)propoxy)imidazo(1,2-C)chinazoline-5-yl)-, hydrochloride (1:2)
  • Aliqopa
  • BAY 80-6946 dihydrochloride
  • BAY-80-6946 Dihydrochloride
  • Copanlisib-dihydrochloride
Experimenteel: Subprotocol Z1G (PTEN loss)

Patients with PTEN loss receive copanlisib IV over 1 hour on days 1, 8, and 15. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity.
Ander: Cytology Specimen Collection Procedure

Optional correlative studies

Andere namen:
  • Cytologische bemonstering
Ander: Laboratory Biomarker Analysis

Undergo molecular analysis

Geneesmiddel: Copanlisib

Given IV

Andere namen:
  • BAAI 80-6946
  • PI3K-remmer BAY 80-6946
  • Baai 80 6946
  • BAAI 806946
  • BAY-80-6946
  • BAY806946
Geneesmiddel: Copanlisib Hydrochloride

Given IV

Andere namen:
  • 5-Pyrimidinecarboxamide, 2-Amino-N-(2,3-dihydro-7-methoxy-8-(3-(4-morfolinyl)propoxy)imidazo(1,2-C)chinazoline-5-yl)-, hydrochloride (1:2)
  • Aliqopa
  • BAY 80-6946 dihydrochloride
  • BAY-80-6946 Dihydrochloride
  • Copanlisib-dihydrochloride
Experimenteel: Subprotocol Z1H (PTEN mutation)

Patients with PTEN mutation receive copanlisib IV over 1 hour on days 1, 8, and 15. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity.
Ander: Cytology Specimen Collection Procedure

Optional correlative studies

Andere namen:
  • Cytologische bemonstering
Ander: Laboratory Biomarker Analysis

Undergo molecular analysis

Geneesmiddel: Copanlisib

Given IV

Andere namen:
  • BAAI 80-6946
  • PI3K-remmer BAY 80-6946
  • Baai 80 6946
  • BAAI 806946
  • BAY-80-6946
  • BAY806946
Geneesmiddel: Copanlisib Hydrochloride

Given IV

Andere namen:
  • 5-Pyrimidinecarboxamide, 2-Amino-N-(2,3-dihydro-7-methoxy-8-(3-(4-morfolinyl)propoxy)imidazo(1,2-C)chinazoline-5-yl)-, hydrochloride (1:2)
  • Aliqopa
  • BAY 80-6946 dihydrochloride
  • BAY-80-6946 Dihydrochloride
  • Copanlisib-dihydrochloride
Experimenteel: Subprotocol Z1I (BRCA1 or BRCA2 gene mutation)

Patients with BRCA1 or BRCA2 gene mutation receive adavosertib PO QD for 5 days for 2 weeks. Cycles repeat every 21 days in the absence of disease progression or unacceptable toxicity.
Ander: Cytology Specimen Collection Procedure

Optional correlative studies

Andere namen:
  • Cytologische bemonstering
Ander: Laboratory Biomarker Analysis

Undergo molecular analysis

Geneesmiddel: Adavosertib

Given PO

Andere namen:
  • AZD-1775
  • AZD1775
  • MK-1775
  • MK1775
  • AZD 1775
  • MK 1775
Experimenteel: Subprotocol Z1K (AKT mutation)

Patients receive ipatasertib PO QD. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity.
Ander: Cytology Specimen Collection Procedure

Optional correlative studies

Andere namen:
  • Cytologische bemonstering
Ander: Laboratory Biomarker Analysis

Undergo molecular analysis

Geneesmiddel: Ipatasertib

Given PO

Andere namen:
  • GDC-0068
  • RG7440
  • RG-7440
  • GDC 0068
  • GDC0068
  • RG 7440
Experimenteel: Subprotocol Z1L (BRAF fusion, aberration or non-V600 mutation)

Patients with a BRAF non-V600 mutation or BRAF fusion, or another BRAF aberration receive ulixertinib (BVD-523FB) PO BID on days 1-28. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity.
Ander: Cytology Specimen Collection Procedure

Optional correlative studies

Andere namen:
  • Cytologische bemonstering
Ander: Laboratory Biomarker Analysis

Undergo molecular analysis

Geneesmiddel: Ulixertinib

Give PO

Andere namen:
  • BVD-523
  • VRT752271
Experimenteel: Subprotocol Z1M (LAG-3 expression >= 1%)

Patients receive nivolumab IV over 30 minutes and relatlimab IV over 30 minutes on day 1.Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity.
Biologisch: Nivolumab

Given IV

Andere namen:
  • BMS-936558
  • MDX-1106
  • NIVO
  • ONO-4538
  • Optie
  • CMAB819
  • Nivolumab Biosimilar CMAB819
  • MDX 1106
  • MDX1106
  • GBS 936558
  • ABP 206
  • Nivolumab Biosimilar ABP 206
  • BCD-263
  • Nivolumab Biosimilar BCD-263
  • BMS936558
  • ONO 4538
  • ONO4538
Ander: Cytology Specimen Collection Procedure

Optional correlative studies

Andere namen:
  • Cytologische bemonstering
Ander: Laboratory Biomarker Analysis

Undergo molecular analysis

Biologisch: Relatlimab

Given IV

Andere namen:
  • BMS-986016
  • BMS986016
  • Immunoglobuline G4, anti-(menselijk lymfocytactiveringsgen-3-eiwit) (menselijke zware keten), disulfide met menselijke lichte keten, dimeer
  • GBS 986016

Wat meet het onderzoek?

Primaire uitkomstmaten

Primaire uitkomstmaten

In het protocol van een klinische studie, de geplande uitkomstmaat die het belangrijkst is voor het evalueren van het effect van een interventie/behandeling. De meeste klinische onderzoeken hebben één primaire uitkomstmaat, maar sommige hebben er meer dan één.
Uitkomstmaat
Maatregel Beschrijving
Tijdsspanne
Objective response rate (ORR)
Tijdsspanne: Up to 3 years

ORR is defined as the percentage of patients whose tumors have a complete or partial response to treatment among analyzable patients. Objective response is defined consistent with Response Evaluation Criteria in Solid Tumors version 1.1, the Cheson (2014) criteria for lymphoma patients, and the Response Assessment in Neuro-Oncology criteria for glioblastoma patients. 90% two-sided confidence interval is calculated for ORR. For the purposes of this study, patients should be re-evaluated for response:

  • For treatments given in 21 day (3 week) cycles: every 3 cycles (9 weeks) for the first 33 cycles, and every 4 cycles thereafter (12 weeks)
  • For treatments given in 28 day (4 week) cycles: every 2 cycles (8 weeks) for the first 26 cycles, and every three cycles thereafter (12 weeks)
  • For treatments given in 42 day (6 week) cycles: every 2 cycles (12 weeks)
Up to 3 years

Secundaire uitkomstmaten

Secundaire uitkomstmaten

In het protocol van een klinische studie, een geplande uitkomstmaat die niet zo belangrijk is als de primaire uitkomstmaat voor het evalueren van het effect van een interventie, maar die nog steeds van belang is. De meeste klinische onderzoeken hebben meer dan één secundaire uitkomstmaat.
Uitkomstmaat
Maatregel Beschrijving
Tijdsspanne
Overall survival (OS)
Tijdsspanne: From start of treatment on that step until death, or censored at the date of last contact, assessed up to 3 years

Will be evaluated specifically for each drug (or step). OS will be estimated using the Kaplan-Meier method.
From start of treatment on that step until death, or censored at the date of last contact, assessed up to 3 years
6-month progression free survival (PFS) rate
Tijdsspanne: From start of treatment on that step until determination of disease progression or death from any cause, censored at the date of last disease assessment for patients who have not progressed, assessed at 6 months

Progression free survival is defined as time from treatment start date to date of progression or death from any cause, whichever occurs first. Disease progression was evaluated using the Response Evaluation Criteria in Solid Tumors version 1.1, the Cheson (2014) criteria for lymphoma patients, and the Response Assessment in Neuro-Oncology criteria for glioblastoma patients. Please refer to the protocol for detailed definitions of disease progression. 6 month PFS rate was estimated using the Kaplan-Meier method, which can provide a point estimate for any specific time point.
From start of treatment on that step until determination of disease progression or death from any cause, censored at the date of last disease assessment for patients who have not progressed, assessed at 6 months
Progression free survival
Tijdsspanne: From start of treatment on that step until determination of disease progression or death from any cause, censored at the date of last disease assessment for patients who have not progressed, assessed up to 3 years

PFS was defined as time from treatment start date to date of disease progression or death from any causes, whichever occurred first. Median PFS was estimated using the Kaplan-Meier method. Disease progression was evaluated using the Response Evaluation Criteria in Solid Tumors version 1.1, the Cheson (2014) criteria for lymphoma patients, and the Response Assessment in Neuro-Oncology criteria for glioblastoma patients. Please refer to the protocol for detailed definitions of disease progression.
From start of treatment on that step until determination of disease progression or death from any cause, censored at the date of last disease assessment for patients who have not progressed, assessed up to 3 years

Medewerkers en onderzoekers

Hier vindt u mensen en organisaties die betrokken zijn bij dit onderzoek.

Sponsor

Sponsor

De organisatie of persoon die het onderzoek initieert en die autoriteit en controle heeft over het onderzoek.
National Cancer Institute (NCI)

Onderzoekers

Onderzoekers

Een onderzoeker die betrokken is bij een klinische studie. Verwante termen zijn onder meer hoofdonderzoeker van de locatie, subonderzoeker van de locatie, onderzoeksvoorzitter, onderzoeksleider en hoofdonderzoeker van de studie.
  • Hoofdonderzoeker: Keith T Flaherty, ECOG-ACRIN Cancer Research Group

Publicaties en nuttige links

De persoon die verantwoordelijk is voor het invoeren van informatie over het onderzoek stelt deze publicaties vrijwillig ter beschikking. Dit kan gaan over alles wat met het onderzoek te maken heeft.

Algemene publicaties

Nuttige links

Studie record data

Deze datums volgen de voortgang van het onderzoeksdossier en de samenvatting van de ingediende resultaten bij ClinicalTrials.gov. Studieverslagen en gerapporteerde resultaten worden beoordeeld door de National Library of Medicine (NLM) om er zeker van te zijn dat ze voldoen aan specifieke kwaliteitscontrolenormen voordat ze op de openbare website worden geplaatst.

Bestudeer belangrijke data

Studie start (Werkelijk)

Studie start

De daadwerkelijke datum waarop de eerste deelnemer aan een klinische studie deelnam. De "verwachte" startdatum van de studie is de datum waarvan de onderzoekers denken dat deze de startdatum van de studie zal zijn.
17 augustus 2015

Primaire voltooiing (Geschat)

Primaire voltooiing

De datum waarop de laatste deelnemer aan een klinische studie is onderzocht of een interventie heeft ondergaan om definitieve gegevens voor de primaire uitkomstmaat te verzamelen. Of de klinische studie volgens het protocol is beëindigd of is beëindigd, heeft geen invloed op deze datum. Voor klinische onderzoeken met meer dan één primaire uitkomstmaat met verschillende voltooiingsdata verwijst deze term naar de datum waarop de gegevensverzameling voor alle primaire uitkomstmaten is voltooid. De "verwachte" primaire voltooiingsdatum is de datum waarvan de onderzoekers denken dat deze de primaire voltooiingsdatum voor het onderzoek zal zijn.
31 december 2027

Studie voltooiing (Geschat)

Studie voltooiing

De datum waarop de laatste deelnemer aan een klinisch onderzoek is onderzocht of een interventie/behandeling heeft ondergaan om definitieve gegevens te verzamelen voor de primaire uitkomstmaten, secundaire uitkomstmaten en bijwerkingen (d.w.z. het laatste bezoek van de laatste deelnemer). De "verwachte" voltooiingsdatum van de studie is de datum waarvan de onderzoekers denken dat deze de voltooiingsdatum van de studie zal zijn.
31 december 2027

Studieregistratiedata

Eerst ingediend

Eerst ingediend

De datum waarop de onderzoekssponsor of onderzoeker voor het eerst een onderzoeksdossier heeft ingediend bij ClinicalTrials.gov. Er is meestal een vertraging van een paar dagen tussen de eerste ingediende datum en de beschikbaarheid van het dossier op ClinicalTrials.gov (de eerste geposte datum).
3 juni 2015

Eerst ingediend dat voldeed aan de QC-criteria

Eerst ingediend dat voldeed aan de QC-criteria

De datum waarop de onderzoekssponsor of onderzoeker voor het eerst een onderzoeksdossier indient dat consistent is met de beoordelingscriteria voor kwaliteitscontrole (QC) van de National Library of Medicine (NLM). De sponsor of onderzoeker moet mogelijk een of meerdere keren een onderzoeksdossier herzien en indienen voordat aan de QC-beoordelingscriteria van NLM wordt voldaan. Het is de verantwoordelijkheid van de sponsor of onderzoeker om ervoor te zorgen dat het onderzoeksdossier consistent is met de NLM QC-beoordelingscriteria.
3 juni 2015

Eerst geplaatst (Geschat)

Eerst geplaatst

De datum waarop het onderzoeksdossier voor het eerst beschikbaar was op ClinicalTrials.gov nadat de beoordeling van de kwaliteitscontrole (QC) van de National Library of Medicine (NLM) is afgerond. Er is meestal een vertraging van een paar dagen tussen de datum waarop de onderzoekssponsor of onderzoeker het onderzoeksdossier heeft ingediend en de eerste geposte datum.
8 juni 2015

Updates van studierecords

Laatste update geplaatst (Werkelijk)

Laatste update geplaatst

De meest recente datum waarop wijzigingen in een onderzoeksdossier beschikbaar zijn gemaakt op ClinicalTrials.gov. Er kan een vertraging optreden tussen het moment waarop de wijzigingen zijn ingediend bij ClinicalTrials.gov door de sponsor of onderzoeker van het onderzoek (de datum waarop de laatste update is ingediend) en de datum waarop de laatste update is gepost.
26 oktober 2026

Laatste update ingediend die voldeed aan QC-criteria

Laatste update ingediend die voldeed aan QC-criteria

De meest recente datum waarop de onderzoekssponsor of onderzoeker wijzigingen in een onderzoeksdossier heeft ingediend die in overeenstemming zijn met de beoordelingscriteria voor kwaliteitscontrole (QC) van de National Library of Medicine (NLM). Het is de verantwoordelijkheid van de sponsor of onderzoeker om ervoor te zorgen dat het onderzoeksdossier consistent is met de NLM QC-beoordelingscriteria.
23 oktober 2026

Laatst geverifieerd

Laatst geverifieerd

De meest recente datum waarop de onderzoekssponsor of onderzoeker de informatie over een klinisch onderzoek op ClinicalTrials.gov als nauwkeurig en actueel heeft bevestigd. Indien een studie met een wervingsstatus van werving; nog niet aan het werven; of actief, geen rekrutering is niet bevestigd in de afgelopen 2 jaar, de rekruteringsstatus van de studie wordt weergegeven als onbekend.
1 september 2026

Meer informatie

Termen gerelateerd aan deze studie

Aanvullende relevante MeSH-voorwaarden

Andere studie-ID-nummers

Andere studie-ID-nummers

Identificatoren of ID-nummers anders dan het NCT-nummer die aan een klinisch onderzoek zijn toegewezen door de sponsor, financiers of anderen van het onderzoek. Deze nummers kunnen unieke identificatoren van andere onderzoeksregisters en subsidienummers van de National Institutes of Health bevatten.
  • NCI-2015-00054
  • U10CA180820 (Subsidie/contract van de Amerikaanse NIH)
  • U24CA196172 (Subsidie/contract van de Amerikaanse NIH)
  • NCI-2015-00054 (Register-ID: CTRP (Clinical Trial Reporting Program))
  • EAY131 (Andere identificatie: CTEP)
  • EAY131 (Andere identificatie: ECOG-ACRIN Cancer Research Group)

Informatie over medicijnen en apparaten, studiedocumenten

Bestudeert een door de Amerikaanse FDA gereguleerd geneesmiddel

Ja

Bestudeert een door de Amerikaanse FDA gereguleerd apparaatproduct

Nee

product vervaardigd in en geëxporteerd uit de V.S.

Nee

Deze informatie is zonder wijzigingen rechtstreeks van de website clinicaltrials.gov gehaald. Als u verzoeken heeft om uw onderzoeksgegevens te wijzigen, te verwijderen of bij te werken, neem dan contact op met register@clinicaltrials.gov. Zodra er een wijziging wordt doorgevoerd op clinicaltrials.gov, wordt deze ook automatisch bijgewerkt op onze website .

Cookie-instellingen

We gebruiken cookies om ervoor te zorgen dat we u de beste ervaring op onze website bieden. Lees ons privacy- en cookiebeleid voor meer informatie. ...>>>U kunt uw voorkeuren op elk moment wijzigen of uw toestemming intrekken door de cookies van uw website of computer te verwijderen zoals beschreven in het beleid. Accepteer het en kies uw voorkeuren door de overeenkomstige vakjes aan te vinken in het gedeelte "Instellingen beheren" hieronder. Lees onze Servicevoorwaarden zorgvuldig door voordat u verder gaat met het gebruiken van enig onderdeel van deze website.
«Beheer instellingen