Pilot RCT of Computer-based Eye Movement Training (CRYSTAL)
3. august 2026 oppdatert av: Glasgow Caledonian University
Computer-based Eye Movement Training for Stroke-related Visual Field Loss: a Pilot Randomised Controlled Trial
The goal of this study is to learn whether NeuroEyeCoach, a computer-based eye movement training programme, can help stroke survivors with visual field loss. The study will also assess whether a larger clinical trial is feasible. The main questions it aims to answer are:
- Can stroke survivors be successfully recruited, randomised and followed up in a larger trial?
- Is NeuroEyeCoach acceptable and practical to use?
- Is there early evidence that NeuroEyeCoach improves vision-related functioning and wellbeing? Researchers will compare NeuroEyeCoach plus usual care with usual care alone.
Participants will:
- Be randomly assigned to receive NeuroEyeCoach plus usual care or usual care alone
- Complete six weeks of training if allocated to NeuroEyeCoach
- Complete questionnaires and tests of vision, daily activities, quality of life, confidence and wellbeing
- Take part in follow-up assessments over six months This pilot trial will include 60 stroke survivors living with visual field loss after stroke. Findings will be used to inform the design of a larger study.
Studieoversikt
Status
Har ikke rekruttert ennå
Forhold
Intervensjon / Behandling
Studietype
Intervensjonell
Registrering (Antatt)
60
Fase
- Ikke aktuelt
Kontakter og plasseringer
Denne delen inneholder kontaktinformasjon for de som utfører studien, og informasjon om hvor denne studien blir utført.
Studiekontakt
- Navn: Christine Hazelton, PhD
- Telefonnummer: 0141 331 8181
- E-post: christine.hazelton@gcu.ac.uk
Deltakelseskriterier
Forskere ser etter personer som passer til en bestemt beskrivelse, kalt kvalifikasjonskriterier. Noen eksempler på disse kriteriene er en persons generelle helsetilstand eller tidligere behandlinger.
Kvalifikasjonskriterier
Alder som er kvalifisert for studier
- Voksen
- Eldre voksen
Tar imot friske frivillige
Nei
Beskrivelse
Inclusion Criteria:
- adult (>18 years)
- stroke survivor
- stroke-related homonymous VFL (minimum quadrantanopia)
- sufficient language, cognitive, and upper limb ability to participate in trial activities.
Exclusion Criteria:
- pre-existing (ie pre-stroke) registration as sight impaired (partially sighted) or severely sight impaired (blind)
- • history of seizure disorders, especially those of a photosensitive nature
Studieplan
Denne delen gir detaljer om studieplanen, inkludert hvordan studien er utformet og hva studien måler.
Hvordan er studiet utformet?
Designdetaljer
- Primært formål: Annen
- Tildeling: Randomisert
- Intervensjonsmodell: Parallell tildeling
- Masking: Enkelt
Våpen og intervensjoner
Deltakergruppe / Arm |
Intervensjon / Behandling |
|---|---|
|
Eksperimentell: Eye movement training + usual care
Usual post-stroke care, plus eye movement training (VISIOcoach)
|
computer based eye movement training for visual field loss in stroke
Usual post-stroke care
|
|
Annen: usual care
Usual post-stroke care
|
Usual post-stroke care
|
Hva måler studien?
Primære resultatmål
Resultatmål |
Tiltaksbeskrivelse |
Tidsramme |
|---|---|---|
|
Recruitment rate
Tidsramme: through study completion, estimated at 15 months
|
Rate of recruitment to the trial
|
through study completion, estimated at 15 months
|
Sekundære resultatmål
Resultatmål |
Tiltaksbeskrivelse |
Tidsramme |
|---|---|---|
|
Retention Rate
Tidsramme: through study completion, estimated at 15 months
|
Rate of retention of participants in the study
|
through study completion, estimated at 15 months
|
|
Screening and eligibility rate
Tidsramme: Active screening period
|
Screening and eligibility rate
|
Active screening period
|
|
Outcome measure completion rate
Tidsramme: over data collection period
|
through study completion, estimated at 15 months
|
over data collection period
|
|
intervention adherence
Tidsramme: 6 weeks
|
adherence to recommended training regime (duration)
|
6 weeks
|
|
Adverse events
Tidsramme: up to 6 weeks
|
any adverse eventa experienced
|
up to 6 weeks
|
|
Support and computer provision needs
Tidsramme: up to 6 weeks
|
To what extent must technical equipment or assistance be given
|
up to 6 weeks
|
|
NEI VFQ 25 (National Eye Institute Visual Function Questionnaire-25)
Tidsramme: baseline, 6 weeks post randomisation, 6 months post randomisation
|
Patient-reported measure of vision-related functioning.
Minimum value is 0, and maximum value is 100; higher scores mean a better outcome
|
baseline, 6 weeks post randomisation, 6 months post randomisation
|
|
EQ-5D 5L
Tidsramme: baseline, 6 weeks post randomisation, 6 months post randomisation
|
Generic health related quality of life Maximum value 1.0; better scores mean a better outcome
|
baseline, 6 weeks post randomisation, 6 months post randomisation
|
|
IReST (International Reading Speed Test)
Tidsramme: baseline, 6 weeks post randomisation, 6 months post randomisation
|
Reading test (words per minute)
|
baseline, 6 weeks post randomisation, 6 months post randomisation
|
|
Melbourne Rapid Fields
Tidsramme: baseline, 6 weeks post randomisation, 6 months post randomisation
|
visual field test
|
baseline, 6 weeks post randomisation, 6 months post randomisation
|
|
Confidence after Stroke Measure
Tidsramme: baseline, 6 weeks post randomisation, 6 months post randomisation
|
Validated questionnaire that explores self-confidence, positive attitude and social confidence Minimum score is 0 and the maximum score is 81; a higher score indicates better outcome Ref: Horne JC, Lincoln NB, Logan PA.
Measurement of confidence: the development and psychometric evaluation of a stroke-specific, measure of confidence.
Clin Rehabil.
2017 Nov;31(11):1529-1537. doi: 10.1177/0269215517705424.
Epub 2017 May 3. PMID: 28466669; PMCID: PMC5652651.
|
baseline, 6 weeks post randomisation, 6 months post randomisation
|
|
Warwick-Edinburgh Mental Wellbeing Scale
Tidsramme: baseline, 6 weeks post randomisation, 6 months post randomisation
|
Mental wellbeing questionnaire Minimum raw score is 7 and the maximum raw score is 35; higher score means a better outcome
|
baseline, 6 weeks post randomisation, 6 months post randomisation
|
|
health care resource use
Tidsramme: baseline, 6 weeks post randomisation, 6 months post randomisation
|
health care resource use, covering general, stroke specific, and vision specific resources
|
baseline, 6 weeks post randomisation, 6 months post randomisation
|
Samarbeidspartnere og etterforskere
Det er her du vil finne personer og organisasjoner som er involvert i denne studien.
Sponsor
Samarbeidspartnere
Studierekorddatoer
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Studer hoveddatoer
Studiestart (Antatt)
1. oktober 2026
Primær fullføring (Antatt)
31. juli 2027
Studiet fullført (Antatt)
31. juli 2027
Datoer for studieregistrering
Først innsendt
3. desember 2025
Først innsendt som oppfylte QC-kriteriene
3. august 2026
Først lagt ut (Faktiske)
7. august 2026
Oppdateringer av studieposter
Sist oppdatering lagt ut (Faktiske)
7. august 2026
Siste oppdatering sendt inn som oppfylte QC-kriteriene
3. august 2026
Sist bekreftet
1. august 2026
Mer informasjon
Begreper knyttet til denne studien
Ytterligere relevante MeSH-vilkår
Andre studie-ID-numre
- HLS/LS/25/032
- TCS/24/40 (Annet stipend/finansieringsnummer: Chief Scientist Office Scotland)
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IPD-planbeskrivelse
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