Effects of Repeated Memory Training on Memory Function and Addiction Related Processes
2020年1月8日 更新者：Johns Hopkins University
Prospective memory is the ability to implement an intention to the future (e.g.
remember to take medication, attend a scheduled meeting), and has receive little attention in addiction.
The investigators propose that prospective memory plays a critical, yet unrecognized, role in major human behavior change such as that required in addiction treatment.
This study will determine the preliminary efficacy of prospective memory training in improving memory and executive functions while reducing illicit drug use in methadone patients.
Participants will be randomly assigned to one of three conditions: an experimental memory training program or one of two comparator memory training programs.
研究概览
地位
终止
条件
研究类型
介入性
注册 (实际的)
1
阶段
- 不适用
联系人和位置
本节提供了进行研究的人员的详细联系信息，以及有关进行该研究的地点的信息。
学习地点
-
-
Maryland
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Baltimore、Maryland、美国、21224
- Johns Hopkins University School of Medicine, Bayview Campus
-
-
参与标准
研究人员寻找符合特定描述的人，称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。
资格标准
适合学习的年龄
18年 至 55年 (成人)
接受健康志愿者
不
有资格学习的性别
全部
描述
Inclusion Criteria:
- Age 18-55; provision of written consent
- Enrolled in a substance use treatment program
- Sex with ≥ 2 partners in the last 30 days and sex without a condom on at least one occasion in the last year
Exclusion Criteria:
- Severe psychiatric conditions associated with psychosis or any unstable psychiatric condition
- History of medical, psychiatric, or neurological conditions associated with significant cognitive impairment
学习计划
本节提供研究计划的详细信息，包括研究的设计方式和研究的衡量标准。
研究是如何设计的？
设计细节
- 主要用途：治疗
- 分配：随机化
- 介入模型：并行分配
- 屏蔽：双倍的
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
|
实验性的：Experimental Memory Training
Experimental memory training program
|
The experimental memory training will be implemented as a computer program that uses state-of-the-art immersive technology to simulate prospective memory in everyday life in which one must remember to carry out tasks throughout the day, while engaging in current ongoing activity.
Participants are asked to imagine they have a work-at-home job (ongoing activity), which is an independent program (CogMed QM) designed to train working memory, but that they also need to remember to carry out a number of tasks throughout the day.
Using a touch screen, participants will need to touch objects in the simulated environment to appropriately interact with these stimuli according to their pre-assigned tasks.
|
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有源比较器：Comparator Memory Training 1
Comparator memory training program
|
The first comparator memory training intervention will utilize the same overall structure and immersive computer environment as the experimental memory intervention, but will not challenge the same aspects of cognition.
|
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有源比较器：Comparator Memory Training 2
Alternative comparator memory training program
|
The second comparator memory training intervention will utilize the same overall structure and immersive computer environment as the experimental memory intervention, but will not challenge the same aspects of cognition.
|
研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Change in prospective memory over course of training
大体时间：one month
|
Prospective memory will be evaluated within the program itself and measured as the percentage of correct responses within the program.
Higher percentages are indicative of greater prospective memory performance.
|
one month
|
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Change in drug use and substance abuse over course of training.
大体时间：one month
|
Drug use will be evaluated by urinalysis.
Negative screens are indicative of drug abstinence.
|
one month
|
合作者和调查者
在这里您可以找到参与这项研究的人员和组织。
调查人员
- 首席研究员：Matthew W Johnson, Ph.D.、Johns Hopkins University
研究记录日期
这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查，以确保它们在发布到公共网站之前符合特定的质量控制标准。
研究主要日期
学习开始 (实际的)
2018年5月1日
初级完成 (实际的)
2019年10月1日
研究完成 (实际的)
2019年10月1日
研究注册日期
首次提交
2017年9月8日
首先提交符合 QC 标准的
2017年9月12日
首次发布 (实际的)
2017年9月15日
研究记录更新
最后更新发布 (实际的)
2020年1月10日
上次提交的符合 QC 标准的更新
2020年1月8日
最后验证
2020年1月1日
更多信息
与本研究相关的术语
其他研究编号
- IRB00138474
计划个人参与者数据 (IPD)
计划共享个人参与者数据 (IPD)？
未定
药物和器械信息、研究文件
研究美国 FDA 监管的药品
不
研究美国 FDA 监管的设备产品
不
此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.
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-
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Experimental memory training的临床试验
-
Karolinska InstitutetMinistry of Health and Social Affairs, Sweden完全的
-
Southern Methodist UniversityKing's College London完全的
-
Mental Health Services in the Capital Region, DenmarkCopenhagen Trial Unit, Center for Clinical Intervention Research; Center for Clinical Intervention...完全的
-
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