CMO Letter to Reduce Unnecessary Antibiotic Prescribing and Broad Spectrum Prescribing Winter 2018-9 (CMO2018-9)
2020年3月2日 更新者:Public Health England
A Randomized Controlled Trial of Behaviourally Informed Feedback Letters Sent by the Chief Medical Officer on the Amount of Antibiotics and the Percentage of Broad Spectrum Antibiotics Prescribed in Primary Care
This trial aims to reduce unnecessary prescription of antibiotics and broad spectrum antibiotics by general practitioners (GPs) in England.
Unnecessary prescriptions are defined as those that do not improve patient health outcomes.
The intervention is to send GPs a letter from the Chief Medical Officer (CMO) that gives feedback on their practice's prescribing levels.
Specifically the sample was GPs whose practices whose prescribed more than 1.161 items per STAR-PU or whose practices prescribed more that .965
items per STAR-PU and greater than 10% broad spectrum items.
The intervention groups received a letter telling them they are among the highest prescribers of either their total or broad spectrum antibiotics, with a graph showing their prescribing compared to average prescribing ("their peers").
The letter also contained a leaflet to help GPs discuss self-care advice with patients and some advice to use delayed prescriptions.
The investigators hypothesize that the antibiotic prescribing rate in will be lower for the treatment group compared to the control group, following the receipt of the letter.
研究概览
地位
完全的
条件
研究类型
介入性
注册 (实际的)
7000
阶段
- 不适用
联系人和位置
本节提供了进行研究的人员的详细联系信息,以及有关进行该研究的地点的信息。
学习地点
-
-
-
London、英国、SE1
- Public Health England
-
-
参与标准
研究人员寻找符合特定描述的人,称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。
资格标准
适合学习的年龄
- 孩子
- 成人
- 年长者
接受健康志愿者
是的
有资格学习的性别
全部
描述
Inclusion Criteria:
- GP practices that prescribed more than 1.161 Antibacterial Items/STAR-PU for the twelve months (June 2017 - May 2018)
- GP practices that prescribed more than 0.965 Antibacterial Items/STAR-PU and also more than 10% broad spectrum items for the twelve months (June 2017 - May 2018).
Exclusion Criteria:
- none
学习计划
本节提供研究计划的详细信息,包括研究的设计方式和研究的衡量标准。
研究是如何设计的?
设计细节
- 主要用途:其他
- 分配:随机化
- 介入模型:并行分配
- 屏蔽:无(打开标签)
武器和干预
参与者组/臂 |
干预/治疗 |
---|---|
实验性的:high total and high broad spectrum prescribing letter
social norm feedback letter with bar chart GPs who prescribe more than 1.161 Antibacterial Items/ STAR-PU and more than 10% broad spectrum receive a letter that has specific information about the percentile they are on for broad spectrum prescribing and a bar chart representing their broad spectrum prescribing compared to the average
|
letter with the percentile prescribing the practice is on and a bar chart, comparing prescribing to the national average
|
有源比较器:high total and high broad spectrum prescribing control
standard social norm feedback letter GPs who prescribe more than 1.161 Antibacterial Items/ STAR-PU and more than 10% broad spectrum receive the standard practice overall prescribing letter as a control
|
social norm feedback letter used as standard practice, without specific information about the prescribing percentile
|
实验性的:high total prescribing only intervention letter
social norm feedback letter with bar chart GPs who prescribe more than 1.161 Antibacterial Items/ STAR-PU and less than 10% broad spectrum receive a letter that has specific information about the percentile they are on for overall prescribing and a bar chart representing their overall prescribing compared to the average
|
letter with the percentile prescribing the practice is on and a bar chart, comparing prescribing to the national average
|
有源比较器:high total prescribing control letter
standard social norm feedback letter GPs who prescribe more than 1.161 Antibacterial Items/ STAR-PU and less than 10% broad spectrum receive the standard practice overall prescribing letter as a control
|
social norm feedback letter used as standard practice, without specific information about the prescribing percentile
|
实验性的:moderate total prescribing and high broad spectrum letter
social norm feedback letter with bar chart GPs who prescribe more than 0.965 but less than 1.161 Antibacterial Items/ STAR-PU and more than 10% broad spectrum will receive a letter that has specific information about the percentile they are on for broad spectrum prescribing and a bar chart representing their broad spectrum prescribing compared to the average
|
letter with the percentile prescribing the practice is on and a bar chart, comparing prescribing to the national average
|
无干预:moderate total prescribing and high broad spectrum control
GPs who prescribe more than 0.965 but less than 1.161 Antibacterial Items/ STAR-PU and more than 10% broad spectrum receive no letter, which is standard practice, as a control.
|
研究衡量的是什么?
主要结果指标
结果测量 |
措施说明 |
大体时间 |
---|---|---|
total antibiotic prescribing weighted by Specific Therapeutic group Age-sex Related Prescribing Unit (STAR-PU) in November for each GP practice
大体时间:1 month
|
antibiotic prescribing weighted by Specific Therapeutic group Age-sex Related Prescribing Unit (STAR-PU)
|
1 month
|
total broad spectrum antibiotic prescribing weighted by STAR-PU in November for each GP practice
大体时间:1 month
|
broad spectrum antibiotic prescribing weighted by Specific Therapeutic group Age-sex Related Prescribing Unit (STAR-PU)
|
1 month
|
percentage broad spectrum antibiotic prescribing in November for each GP practice
大体时间:1 month
|
percentage broad spectrum antibiotic prescribing
|
1 month
|
total non-broad spectrum antibiotic prescribing weighted by STAR-PU in November for each GP practice
大体时间:1 month
|
total overall antibiotic prescribing minus total broad spectrum antibiotic prescribing
|
1 month
|
total antibiotic prescribing weighted by STAR-PU in December for each GP practice
大体时间:2 months
|
antibiotic prescribing weighted by Specific Therapeutic group Age-sex Related Prescribing Unit (STAR-PU)
|
2 months
|
total broad spectrum antibiotic prescribing weighted by STAR-PU in December for each GP practice
大体时间:2 months
|
2 months
|
|
percentage broad spectrum antibiotic prescribing in December for each GP practice
大体时间:2 months
|
2 months
|
|
total non-broad spectrum antibiotic prescribing weighted by STAR-PU in December for each GP practice
大体时间:2 months
|
2 months
|
|
total antibiotic prescribing in January weighted by STAR-PU for each GP practice
大体时间:3 months
|
3 months
|
|
total broad spectrum antibiotic prescribing weighted by STAR-PU in January for each GP practice
大体时间:3 months
|
3 months
|
|
percentage broad spectrum antibiotic prescribing in January for each GP practice
大体时间:3 months
|
3 months
|
|
total non-broad spectrum antibiotic prescribing weighted by STAR-PU in January for each GP practice
大体时间:3 months
|
3 months
|
|
total antibiotic prescribing weighted by STAR-PU in February for each GP practice
大体时间:4 months
|
4 months
|
|
total broad spectrum antibiotic prescribing weighted by STAR-PU in February for each GP practice
大体时间:4 months
|
4 months
|
|
percentage broad spectrum antibiotic prescribing in February for each GP practice
大体时间:4 months
|
4 months
|
|
total non-broad spectrum antibiotic prescribing weighted by STAR-PU in February for each GP practice
大体时间:4 months
|
4 months
|
|
total antibiotic prescribing weighted by STAR-PU in March for each GP practice
大体时间:5 months
|
5 months
|
|
total broad spectrum antibiotic prescribing weighted by STAR-PU in March for each GP practice
大体时间:5 months
|
5 months
|
|
percentage broad spectrum antibiotic prescribing in March for each GP practice
大体时间:5 months
|
5 months
|
|
total non-broad spectrum antibiotic prescribing weighted by STAR-PU in March for each GP practice
大体时间:5 months
|
5 months
|
|
total antibiotic prescribing weighted by STAR-PU in April for each GP practice
大体时间:6 months
|
6 months
|
|
total broad spectrum antibiotic prescribing weighted by STAR-PU in April for each GP practice
大体时间:6 months
|
6 months
|
|
percentage broad spectrum antibiotic prescribing in April for each GP practice
大体时间:6 months
|
6 months
|
|
total non-broad spectrum antibiotic prescribing weighted by STAR-PU in April for each GP practice
大体时间:6 months
|
6 months
|
合作者和调查者
在这里您可以找到参与这项研究的人员和组织。
出版物和有用的链接
负责输入研究信息的人员自愿提供这些出版物。这些可能与研究有关。
研究记录日期
这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查,以确保它们在发布到公共网站之前符合特定的质量控制标准。
研究主要日期
学习开始 (实际的)
2018年11月1日
初级完成 (实际的)
2019年4月30日
研究完成 (实际的)
2019年5月30日
研究注册日期
首次提交
2019年2月27日
首先提交符合 QC 标准的
2019年3月1日
首次发布 (实际的)
2019年3月5日
研究记录更新
最后更新发布 (实际的)
2020年3月3日
上次提交的符合 QC 标准的更新
2020年3月2日
最后验证
2018年12月1日
更多信息
与本研究相关的术语
其他研究编号
- R&D 193
药物和器械信息、研究文件
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不
研究美国 FDA 监管的设备产品
不
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