Neuromuscular and Cognitive Fatigue During a 24 Hour Treadmill Running Exercise

June 10, 2009 updated by: Centre Hospitalier Universitaire de Saint Etienne

Neuromuscular and Cognitive Fatigue During a 24h Treadmill Running Exercise.

The main purpose of the present study is to determine the relative contributions of central and peripheral fatigue during an ultra-endurance exercise.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

For that purpose, 14 subjects running 24 hours on a treadmill will be compared with a control group being awake during the same period. Subjects who running will have electrically evoked forces on the muscles associated EMG activity, blood samples and muscle biopsy.

Study Type

Interventional

Enrollment (Actual)

30

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • France
      • Saint-etienne, France, 42055
        • Pr André GEYSSANT

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 60 years (Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • The subjects of the experimental group will be recruited among experienced ultra-runners . They all have run at least a 12 hour race or longer.
  • The control group will be recruited among experienced ultra-runners . Age of control group will be age experimental group more or less 2 years.

Exclusion Criteria:

  • The subjects will not be selected if:

    • they were injured in the 3 months before the experiment
    • they had a tendon or joint pathology that could impair strength measurements.
    • they participate to an other experiment at the same time

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Health Services Research
  • Allocation: Non-Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: 1
patients running during 24 hours without sleep
Procedure: running during 24 hours without sleep
patients running during 24 hours without sleep
Placebo Comparator: 2
patients without sleep during 24 hours
Other: no sleeping
patients without sleep during 24 hours

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
-Voluntary and electrically evoked forces on the contracted muscles
Time Frame: 24 hours
24 hours

Secondary Outcome Measures

Outcome Measure
Time Frame
Electrically evoked forces on the relaxed muscles and associated EMG activity
Time Frame: 24 hours
24 hours
Blood samples before the exercise
Time Frame: every 4 hours
every 4 hours
Muscle biopsy (vastus lateralis)
Time Frame: before and after the exercise
before and after the exercise

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Centre Hospitalier Universitaire de Saint Etienne

Investigators

  • Study Chair: DENIS Christian, Professor, Service de médecine du sport, CHU SAINT-ETIENNE

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

September 1, 2007

Primary Completion (Actual)

December 1, 2007

Study Completion (Actual)

December 1, 2007

Study Registration Dates

First Submitted

January 29, 2007

First Submitted That Met QC Criteria

January 29, 2007

First Posted (Estimate)

January 30, 2007

Study Record Updates

Last Update Posted (Estimate)

June 11, 2009

Last Update Submitted That Met QC Criteria

June 10, 2009

Last Verified

June 1, 2009

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 0601095
  • DGS 2006-0111
  • 2006-A00312-49

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

product manufactured in and exported from the U.S.

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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